DK139388B - Fremgangsmåde til fremstilling af 2-amino-4-hydroxy-7,7-dimethyl-7,8-dihydropteridiner eller tautomere heraf eller salte af disse forbindelser. - Google Patents

Fremgangsmåde til fremstilling af 2-amino-4-hydroxy-7,7-dimethyl-7,8-dihydropteridiner eller tautomere heraf eller salte af disse forbindelser.

Info

Publication number
DK139388B
DK139388B DK348471AA DK348471A DK139388B DK 139388 B DK139388 B DK 139388B DK 348471A A DK348471A A DK 348471AA DK 348471 A DK348471 A DK 348471A DK 139388 B DK139388 B DK 139388B
Authority
DK
Denmark
Prior art keywords
dihydropteridines
tautomers
hydroxy
dimethyl
salts
Prior art date
Application number
DK348471AA
Other languages
Danish (da)
English (en)
Other versions
DK139388C (cs
Inventor
Hamish Christopher Swan Wood
Alexander Stuart
Adrian Charles Ward Curran
Saieba Al-Hassan
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Found filed Critical Wellcome Found
Priority to DK557476A priority Critical patent/DK140633B/da
Publication of DK139388B publication Critical patent/DK139388B/da
Application granted granted Critical
Publication of DK139388C publication Critical patent/DK139388C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/47One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C201/00Preparation of esters of nitric or nitrous acid or of compounds containing nitro or nitroso groups bound to a carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C201/00Preparation of esters of nitric or nitrous acid or of compounds containing nitro or nitroso groups bound to a carbon skeleton
    • C07C201/06Preparation of nitro compounds
    • C07C201/12Preparation of nitro compounds by reactions not involving the formation of nitro groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/132Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group
    • C07C29/136Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH
    • C07C29/147Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of carboxylic acids or derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00Preparation of carboxylic acid esters
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00Preparation of carboxylic acid esters
    • C07C67/08Preparation of carboxylic acid esters by reacting carboxylic acids or symmetrical anhydrides with the hydroxy or O-metal group of organic compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48Two nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D475/00Heterocyclic compounds containing pteridine ring systems
    • C07D475/02Heterocyclic compounds containing pteridine ring systems with an oxygen atom directly attached in position 4
    • C07D475/04Heterocyclic compounds containing pteridine ring systems with an oxygen atom directly attached in position 4 with a nitrogen atom directly attached in position 2

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK348471AA 1970-07-27 1971-07-14 Fremgangsmåde til fremstilling af 2-amino-4-hydroxy-7,7-dimethyl-7,8-dihydropteridiner eller tautomere heraf eller salte af disse forbindelser. DK139388B (da)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DK557476A DK140633B (da) 1970-07-27 1976-12-10 2,4-Diamino-6-hydroxy-5-nitropyrimidinderivater og fremgangsmåde til deres fremstilling.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB3628970A GB1363064A (en) 1970-07-27 1970-07-27 Pyrimidine derivatives as intermediates in the synthesis of pteridines

Publications (2)

Publication Number Publication Date
DK139388B true DK139388B (da) 1979-02-12
DK139388C DK139388C (cs) 1979-07-30

Family

ID=10386747

Family Applications (1)

Application Number Title Priority Date Filing Date
DK348471AA DK139388B (da) 1970-07-27 1971-07-14 Fremgangsmåde til fremstilling af 2-amino-4-hydroxy-7,7-dimethyl-7,8-dihydropteridiner eller tautomere heraf eller salte af disse forbindelser.

Country Status (21)

Country Link
US (1) US3810893A (cs)
JP (1) JPS5439397B1 (cs)
AT (1) AT311355B (cs)
BE (1) BE770577A (cs)
CA (1) CA997760A (cs)
CH (1) CH569014A5 (cs)
CS (1) CS179373B2 (cs)
DD (1) DD95386A5 (cs)
DE (1) DE2137339C2 (cs)
DK (1) DK139388B (cs)
ES (1) ES393486A1 (cs)
FI (1) FI52090C (cs)
FR (1) FR2100955B1 (cs)
GB (1) GB1363064A (cs)
HU (1) HU165163B (cs)
IE (2) IE36470B1 (cs)
IL (1) IL37252A (cs)
NL (1) NL172240C (cs)
PL (1) PL75064B1 (cs)
SE (2) SE389116B (cs)
ZA (1) ZA714379B (cs)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4036961A (en) * 1972-08-01 1977-07-19 Burroughs Wellcome Co. Pharmaceutical compositions containing pteridines
GB1451043A (en) * 1972-08-01 1976-09-29 Wellcome Found Biologicylly acitve compounds and compositions
US4042589A (en) * 1972-08-01 1977-08-16 Burroughs Wellcome Co. Pteridine compounds
GB1454165A (en) * 1972-08-01 1976-10-27 Wellcome Found Biologically active compounds and compositions
US4156725A (en) * 1972-08-01 1979-05-29 Burroughs Wellcome Co. Bacteriostatic biologically active compositions
GB1453831A (en) * 1972-08-01 1976-10-27 Wellcome Found Biologically active compounds and compositions
US4073786A (en) * 1973-07-30 1978-02-14 Burroughs Wellcome Co. 2-Amino-4-hydroxy-6-hydroxymethyl-7,7-diethyl-7,8-dihydropteridine and the 7-spirocyclohexyl analogue thereof
US5196533A (en) * 1983-04-11 1993-03-23 South Alabama Medical Science Foundation, Usa Cyclization of 5 amino-pyrimidines to quinoid 6,6 disubstituted dihydropteridines
US7375093B2 (en) * 2002-07-05 2008-05-20 Intrexon Corporation Ketone ligands for modulating the expression of exogenous genes via an ecdysone receptor complex

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3635978A (en) * 1969-01-28 1972-01-18 Univ Strathclyde Amino pyrimidines

Also Published As

Publication number Publication date
FR2100955A1 (cs) 1972-03-24
DD95386A5 (cs) 1973-02-05
PL75064B1 (cs) 1974-12-31
GB1363064A (en) 1974-08-14
BE770577A (fr) 1972-01-27
NL172240B (nl) 1983-03-01
US3810893A (en) 1974-05-14
CA997760A (en) 1976-09-28
HU165163B (cs) 1974-06-28
IE36470B1 (en) 1976-11-10
FI52090C (fi) 1977-06-10
FR2100955B1 (cs) 1974-09-06
CS179373B2 (en) 1977-10-31
NL7110324A (cs) 1972-01-31
SE389116B (sv) 1976-10-25
FI52090B (cs) 1977-02-28
NL172240C (nl) 1983-08-01
ZA714379B (en) 1973-02-28
DK139388C (cs) 1979-07-30
ES393486A1 (es) 1974-10-01
IE36469B1 (en) 1976-11-10
DE2137339C2 (de) 1984-12-06
AT311355B (de) 1973-11-12
CH569014A5 (cs) 1975-11-14
SE7509609A0 (sv) 1975-08-29
IL37252A (en) 1975-02-10
IE36469L (en) 1972-01-27
DE2137339A1 (de) 1972-03-23
JPS5439397B1 (cs) 1979-11-27
IL37252A0 (en) 1971-10-20

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