DK1392285T3 - Lægemiddel indeholdende en effektor for glutathion-metabolismen sammen med alfa-liponsyre til brug ved nyreerstatningsterapi - Google Patents

Lægemiddel indeholdende en effektor for glutathion-metabolismen sammen med alfa-liponsyre til brug ved nyreerstatningsterapi

Info

Publication number
DK1392285T3
DK1392285T3 DK02747189T DK02747189T DK1392285T3 DK 1392285 T3 DK1392285 T3 DK 1392285T3 DK 02747189 T DK02747189 T DK 02747189T DK 02747189 T DK02747189 T DK 02747189T DK 1392285 T3 DK1392285 T3 DK 1392285T3
Authority
DK
Denmark
Prior art keywords
effector
alpha
lipoic acid
replacement therapy
drug containing
Prior art date
Application number
DK02747189T
Other languages
English (en)
Inventor
Michael Taeger
Gerhard Fries
Dieter Koegst
Siegfried Ansorge
Original Assignee
Serumwerk Bernburg Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Serumwerk Bernburg Ag filed Critical Serumwerk Bernburg Ag
Application granted granted Critical
Publication of DK1392285T3 publication Critical patent/DK1392285T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/38Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/385Heterocyclic compounds having sulfur as a ring hetero atom having two or more sulfur atoms in the same ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/401Proline; Derivatives thereof, e.g. captopril
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • A61P39/06Free radical scavengers or antioxidants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK02747189T 2001-05-28 2002-05-24 Lægemiddel indeholdende en effektor for glutathion-metabolismen sammen med alfa-liponsyre til brug ved nyreerstatningsterapi DK1392285T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10125883A DE10125883A1 (de) 2001-05-28 2001-05-28 Arzneimittel enthaltend einen Effektor des Glutathionmetabolismus zusammen mit alpha-Liponsäure im Rahmen der Nierenersatztherapie
PCT/DE2002/001991 WO2002096414A1 (de) 2001-05-28 2002-05-24 Arzneimittel enthaltend einen effektor des glutathionmetabolismus zusammen mit alpha-liponsäure im rahmen der nierenersatztherapie

Publications (1)

Publication Number Publication Date
DK1392285T3 true DK1392285T3 (da) 2005-06-13

Family

ID=7686362

Family Applications (1)

Application Number Title Priority Date Filing Date
DK02747189T DK1392285T3 (da) 2001-05-28 2002-05-24 Lægemiddel indeholdende en effektor for glutathion-metabolismen sammen med alfa-liponsyre til brug ved nyreerstatningsterapi

Country Status (17)

Country Link
US (1) US7531567B2 (da)
EP (1) EP1392285B1 (da)
JP (1) JP4245926B2 (da)
CN (1) CN100435793C (da)
AR (1) AR034336A1 (da)
AT (1) ATE288750T1 (da)
BR (1) BR0209732A (da)
CA (1) CA2446673C (da)
DE (3) DE10125883A1 (da)
DK (1) DK1392285T3 (da)
ES (1) ES2237683T3 (da)
HK (1) HK1063606A1 (da)
MX (1) MXPA03010833A (da)
PE (1) PE20030090A1 (da)
PT (1) PT1392285E (da)
RU (1) RU2285525C2 (da)
WO (1) WO2002096414A1 (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10125882B4 (de) * 2001-05-28 2007-03-29 Esparma Gmbh Arzneimittel enthaltend Ambroxol, dessen Salze und/oder Prodrugs zusammen mit α-Liponsäure im Rahmen der Behandlung des Diabetes mellitus
DE10258239A1 (de) * 2002-12-13 2004-06-24 Degussa Ag Formulierung enthaltend alpha-Liponsäure(-Derivate) als alleinigen Wirkstoff bei nichtchronischen alkoholinduzierten Intoxikationen
DE10303229B4 (de) * 2003-01-28 2007-07-26 Keyneurotek Ag Ambroxol und Inhibitoren des Angiotensin Converting-Enzyms (ACE) umfassende Arzneimittel Arzneimittel-Zubereitung und ihre Verwendung zur Behandlung von neurodegenerativen Erkrankungen
DE10360954B3 (de) * 2003-12-23 2005-08-18 Esparma Gmbh Verwendung von Silibinin, dessen Salzen und/oder dessen Prodrugs zusammen mit α-Liponsäure zur Behandlung chronisch obstruktiver Lungenerkrankungen
WO2006058248A2 (en) * 2004-11-24 2006-06-01 Hill's Pet Nutrition, Inc. Methods for increasing the immune response in an animal
DK2638915T3 (da) * 2008-07-18 2017-01-30 A1M Pharma Ab Medicinsk anvendelse af radikalbinderen og antioxidanten alfa-1-mikroglobulin
WO2010065069A2 (en) * 2008-12-01 2010-06-10 In Vasc Therapeutics, Inc. Compositions comprising renin-angiotensin aldosterone system inhibitors and lipoic acid compounds, and the use thereof for the treatment of renin-angiotensin aldosterone system related disorders
RU2530601C2 (ru) * 2012-10-05 2014-10-10 Федеральное Государственное Бюджетное Учреждение Науки Институт Молекулярной Биологии Им. В.А. Энгельгардта Российской Академии Наук (Имб Ран) Ингибитор образования цинк-зависимых димеров бета-амилоида
CN106955270B (zh) * 2017-04-14 2018-04-27 黑龙江中桂制药有限公司 一种盐酸氨溴索口服溶液及其制备方法与新用途

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3530761A1 (de) 1985-08-28 1987-03-05 Klinge Co Chem Pharm Fab Arzneimittelkombination mit synergistischer wirkung
DE3804858A1 (de) * 1988-02-17 1989-08-31 Thomae Gmbh Dr K Mittel gegen hyperurikaemie
EP0812590A3 (de) * 1989-11-09 1999-06-09 ASTA Medica Aktiengesellschaft Verwendung von R-Alpha-Liponsäure zur Zytoprotektion
HU208949B (en) 1989-12-22 1994-02-28 Egyt Gyogyszervegyeszeti Gyar Process for producing 4-trans-/4-isopropyliden-amino/-cyclohexanol
ES2112874T3 (es) 1991-07-05 1998-04-16 Asta Medica Ag Utilizacion de acidos carboxilicos con contenido en azufre para combatir trastornos de excitacion de origen patofisiologico.
DE4343592C2 (de) 1993-12-21 1998-04-16 Asta Medica Ag Verwendung von R-(+)-alpha-Liponsäure und dessen Metaboliten in Form der freien Säure oder als Salze oder Ester oder Amide zur Behandlung von Glukosestoffwechselstörungen des zentralen Nervensystems
DE4420102A1 (de) * 1994-06-09 1995-12-14 Asta Medica Ag Arzneimittelkombinationen aus alpha-Liponsäure und herz-kreislaufaktiven Substanzen
DE4439477C2 (de) * 1994-11-08 1999-10-21 Asta Medica Ag Verwendung von R,S-(+/-)-alpha-Liponsäure, R-(+)-alpha-Liponäure, S-(-)-alpha-Liponsäure in reduzierter oder oxidierter Form oder der Metabolite sowie deren Salze, Ester, Amide zur Behandlung der diabetischen Mikroangiopathie
JP3670016B2 (ja) 1994-12-16 2005-07-13 ワーナー−ランバート・カンパニー カプレットをカプセル内に封入する方法及びかかる方法により得ることができる固体剤形
US6245350B1 (en) 1994-12-16 2001-06-12 Warner-Lambert Company Process for encapsulation of caplets in a capsule and solid dosage forms obtainable by such process
AU5347996A (en) 1995-04-26 1996-11-18 Taisho Pharmaceutical Co., Ltd. Preparation for oral administration
HUP9601442A3 (en) 1995-07-25 1999-03-29 Panacea Biotec Ltd Nes antinflammatory and analgetic pharmaceutical compositions, containing nimesulid for transdermal use, and process for producing them
DE19806354B4 (de) * 1998-02-10 2004-09-16 Bdd Group Holding Ag Verwendung von α-Liponsäure oder deren physiologisch verträgliche Salze zur Behandlung von LDL-Hypercholesterinämie
IT1311924B1 (it) 1999-04-13 2002-03-20 Nicox Sa Composti farmaceutici.
DE19933148A1 (de) 1999-07-20 2001-01-25 Boehringer Ingelheim Int Ambroxolhaltige Lutschtablette

Also Published As

Publication number Publication date
EP1392285B1 (de) 2005-02-09
CN1531429A (zh) 2004-09-22
CN100435793C (zh) 2008-11-26
US20040127550A1 (en) 2004-07-01
DE50202227D1 (de) 2005-03-17
HK1063606A1 (en) 2005-01-07
BR0209732A (pt) 2004-09-14
DE10292279D2 (de) 2004-05-06
RU2285525C2 (ru) 2006-10-20
JP4245926B2 (ja) 2009-04-02
MXPA03010833A (es) 2004-11-22
PE20030090A1 (es) 2003-04-01
CA2446673C (en) 2010-12-14
JP2004535410A (ja) 2004-11-25
PT1392285E (pt) 2005-06-30
AR034336A1 (es) 2004-02-18
ES2237683T3 (es) 2005-08-01
EP1392285A1 (de) 2004-03-03
ATE288750T1 (de) 2005-02-15
WO2002096414A1 (de) 2002-12-05
CA2446673A1 (en) 2002-12-05
US7531567B2 (en) 2009-05-12
RU2003137772A (ru) 2005-05-27
DE10125883A1 (de) 2002-12-12

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