PL375074A1 - Ortho-substituted benzoic acid derivatives for the treatment of insulin resistance - Google Patents
Ortho-substituted benzoic acid derivatives for the treatment of insulin resistanceInfo
- Publication number
- PL375074A1 PL375074A1 PL03375074A PL37507403A PL375074A1 PL 375074 A1 PL375074 A1 PL 375074A1 PL 03375074 A PL03375074 A PL 03375074A PL 37507403 A PL37507403 A PL 37507403A PL 375074 A1 PL375074 A1 PL 375074A1
- Authority
- PL
- Poland
- Prior art keywords
- ortho
- treatment
- benzoic acid
- acid derivatives
- insulin resistance
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/32—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
- C07C235/34—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/62—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Emergency Medicine (AREA)
- Child & Adolescent Psychology (AREA)
- Vascular Medicine (AREA)
- Epidemiology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0201935A SE0201935D0 (en) | 2002-06-20 | 2002-06-20 | Therapeutic agents |
| SE0203826A SE0203826D0 (en) | 2002-12-20 | 2002-12-20 | Therapeutic agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL375074A1 true PL375074A1 (en) | 2005-11-14 |
Family
ID=30002442
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL03375074A PL375074A1 (en) | 2002-06-20 | 2003-06-17 | Ortho-substituted benzoic acid derivatives for the treatment of insulin resistance |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US7355069B2 (en) |
| EP (1) | EP1517883B8 (en) |
| JP (2) | JP3782818B2 (en) |
| KR (1) | KR20050014013A (en) |
| CN (1) | CN1319938C (en) |
| AR (1) | AR039713A1 (en) |
| AT (1) | ATE386013T1 (en) |
| AU (1) | AU2003240099B2 (en) |
| BR (1) | BR0311932A (en) |
| CA (1) | CA2489834C (en) |
| DE (1) | DE60319084T2 (en) |
| DK (1) | DK1517883T3 (en) |
| ES (1) | ES2299702T3 (en) |
| HK (1) | HK1073838A1 (en) |
| IL (1) | IL165671A0 (en) |
| IS (1) | IS7627A (en) |
| MX (1) | MXPA04012686A (en) |
| NO (1) | NO20045353L (en) |
| PL (1) | PL375074A1 (en) |
| PT (1) | PT1517883E (en) |
| RU (1) | RU2004137094A (en) |
| TW (1) | TWI282784B (en) |
| WO (1) | WO2004000790A1 (en) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6262118B1 (en) * | 1999-06-04 | 2001-07-17 | Metabolex, Inc. | Use of (-) (3-trihalomethylphenoxy) (4-halophenyl) acetic acid derivatives for treatment of insulin resistance, type 2 diabetes and hyperlipidemia |
| US7576131B2 (en) * | 1999-06-04 | 2009-08-18 | Metabolex, Inc. | Use of (-) (3-trihalomethylphenoxy) (4-halophenyl) acetic acid derivatives for treatment of insulin resistance, type 2 diabetes, hyperlipidemia and hyperuricemia |
| SE0104333D0 (en) | 2001-12-19 | 2001-12-19 | Astrazeneca Ab | Therapeutic agents |
| FR2875805B1 (en) * | 2004-09-27 | 2006-12-29 | Genfit S A | SUBSTITUTED N- (BENZYL) PHENYLACETAMIDE DERIVATIVE COMPOUNDS, PREPARATION AND USES |
| GB0522431D0 (en) * | 2005-11-03 | 2005-12-14 | Astrazeneca Ab | Chemical process |
| GB0522433D0 (en) * | 2005-11-03 | 2005-12-14 | Astrazeneca Ab | Therapeutic agents |
Family Cites Families (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK148576A (en) | 1975-04-18 | 1976-10-19 | Boehringer Mannheim Gmbh | PHENYLALCANCARBONIC ACID DERIVATIVES AND PROCEDURE FOR THEIR PREPARATION |
| DE19615263A1 (en) * | 1996-04-18 | 1997-10-23 | Bayer Ag | Benzyloxy substituted phenylglycinolamides |
| CA2306825A1 (en) | 1997-10-17 | 1999-04-29 | Avantis Pharmaceuticals Products Inc. | Therapeutic uses of quinoline derivatives |
| RU2226529C2 (en) | 1997-12-19 | 2004-04-10 | Шеринг Акциенгезельшафт | Derivatives of ortho-antranilamide as anti-coagulating agents, pharmaceutical composition and method for treatment |
| SE9801992D0 (en) | 1998-06-04 | 1998-06-04 | Astra Ab | New 3-aryl-2-hydroxypropionic acid derivative I |
| GB9822473D0 (en) | 1998-10-16 | 1998-12-09 | Glaxo Group Ltd | Chemical compounds |
| ES2287016T3 (en) | 1999-04-28 | 2007-12-16 | Sanofi-Aventis Deutschland Gmbh | DERIVATIVES OF DIARIL-ACID AS LIGANDS OF THE PPAR RECEIVER. |
| SK15522001A3 (en) | 1999-04-28 | 2002-06-04 | Aventis Pharma Deutschland Gmbh | Tri-aryl acid derivatives as ppar receptor ligands |
| JP4618845B2 (en) * | 1999-06-09 | 2011-01-26 | 杏林製薬株式会社 | Substituted phenylpropionic acid derivatives as human peroxisome proliferator-activated receptor (PPAR) alpha agonists |
| GB9919411D0 (en) | 1999-08-18 | 1999-10-20 | Zeneca Ltd | Chemical compounds |
| SE0000772D0 (en) | 2000-03-08 | 2000-03-08 | Astrazeneca Ab | Chemical compounds |
| US6509374B2 (en) | 2000-04-17 | 2003-01-21 | Novo Nordisk A/S | Compounds, their preparation and use |
| SE0003766D0 (en) | 2000-10-18 | 2000-10-18 | Astrazeneca Ab | Novel formulation |
| EG26979A (en) | 2000-12-21 | 2015-03-01 | Astrazeneca Ab | Chemical compounds |
| GB0116955D0 (en) | 2001-07-11 | 2001-09-05 | Syngenta Ltd | Weed control process |
| GB0121337D0 (en) | 2001-09-04 | 2001-10-24 | Astrazeneca Ab | Chemical compounds |
| GB0121621D0 (en) | 2001-09-07 | 2001-10-31 | Astrazeneca Ab | Chemical compounds |
| GB0121622D0 (en) | 2001-09-07 | 2001-10-31 | Astrazeneca Ab | Chemical compounds |
| PL216023B1 (en) | 2001-09-08 | 2014-02-28 | Astrazeneca Ab | Benzothiazepine and benzothiadiazepine derivatives with ileal bile acid transport (ibat) inhibitory activity for the treatment hyperlipidaemia |
| SE0104334D0 (en) | 2001-12-19 | 2001-12-19 | Astrazeneca Ab | Therapeutic agents |
| SE0104333D0 (en) | 2001-12-19 | 2001-12-19 | Astrazeneca Ab | Therapeutic agents |
| GB0229931D0 (en) | 2002-12-21 | 2003-01-29 | Astrazeneca Ab | Therapeutic agents |
| GB0209467D0 (en) | 2002-04-25 | 2002-06-05 | Astrazeneca Ab | Chemical compounds |
| GB0213669D0 (en) | 2002-06-14 | 2002-07-24 | Astrazeneca Ab | Chemical compounds |
| SE0201936D0 (en) | 2002-06-20 | 2002-06-20 | Astrazeneca Ab | Therapeutic agents |
| SE0201937D0 (en) | 2002-06-20 | 2002-06-20 | Astrazeneca Ab | Therapeutic agents |
| US7351858B2 (en) | 2002-06-20 | 2008-04-01 | Astrazeneca Ab | Ortho-substituted benzoic acid derivatives for the treatment of insulin resistance |
| GB0314130D0 (en) | 2003-06-18 | 2003-07-23 | Astrazeneca Ab | Therapeutic agents |
| GB0314136D0 (en) | 2003-06-18 | 2003-07-23 | Astrazeneca Ab | Therapeutic agents |
| GB0314075D0 (en) | 2003-06-18 | 2003-07-23 | Astrazeneca Ab | Therapeutic agents |
| GB0314129D0 (en) | 2003-06-18 | 2003-07-23 | Astrazeneca Ab | Therapeutic agents |
| GB0314078D0 (en) | 2003-06-18 | 2003-07-23 | Astrazeneca Ab | Therapeutic agents |
| GB0314131D0 (en) | 2003-06-18 | 2003-07-23 | Astrazeneca Ab | Therapeutic agents |
| GB0314260D0 (en) | 2003-06-19 | 2003-07-23 | Astrazeneca Ab | Therapeutic agents |
-
2003
- 2003-06-17 DE DE60319084T patent/DE60319084T2/en not_active Expired - Lifetime
- 2003-06-17 DK DK03732713T patent/DK1517883T3/en active
- 2003-06-17 US US10/518,007 patent/US7355069B2/en not_active Expired - Fee Related
- 2003-06-17 PL PL03375074A patent/PL375074A1/en not_active Application Discontinuation
- 2003-06-17 MX MXPA04012686A patent/MXPA04012686A/en not_active Application Discontinuation
- 2003-06-17 AT AT03732713T patent/ATE386013T1/en not_active IP Right Cessation
- 2003-06-17 WO PCT/GB2003/002584 patent/WO2004000790A1/en active IP Right Grant
- 2003-06-17 JP JP2004515007A patent/JP3782818B2/en not_active Expired - Lifetime
- 2003-06-17 RU RU2004137094/04A patent/RU2004137094A/en not_active Application Discontinuation
- 2003-06-17 BR BR0311932-7A patent/BR0311932A/en not_active IP Right Cessation
- 2003-06-17 TW TW092116378A patent/TWI282784B/en not_active IP Right Cessation
- 2003-06-17 CA CA002489834A patent/CA2489834C/en not_active Expired - Fee Related
- 2003-06-17 ES ES03732713T patent/ES2299702T3/en not_active Expired - Lifetime
- 2003-06-17 PT PT03732713T patent/PT1517883E/en unknown
- 2003-06-17 KR KR10-2004-7020670A patent/KR20050014013A/en not_active Application Discontinuation
- 2003-06-17 AU AU2003240099A patent/AU2003240099B2/en not_active Ceased
- 2003-06-17 CN CNB038194740A patent/CN1319938C/en not_active Expired - Fee Related
- 2003-06-17 EP EP03732713A patent/EP1517883B8/en not_active Expired - Lifetime
- 2003-06-20 AR ARP030102197A patent/AR039713A1/en not_active Application Discontinuation
-
2004
- 2004-12-07 NO NO20045353A patent/NO20045353L/en not_active Application Discontinuation
- 2004-12-09 IL IL16567104A patent/IL165671A0/en unknown
-
2005
- 2005-01-05 IS IS7627A patent/IS7627A/en unknown
- 2005-07-26 HK HK05106401A patent/HK1073838A1/en not_active IP Right Cessation
-
2006
- 2006-01-27 JP JP2006019068A patent/JP2006182782A/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| AU2003240099A1 (en) | 2004-01-06 |
| RU2004137094A (en) | 2005-08-10 |
| IS7627A (en) | 2005-01-05 |
| TWI282784B (en) | 2007-06-21 |
| CA2489834C (en) | 2006-10-03 |
| ATE386013T1 (en) | 2008-03-15 |
| IL165671A0 (en) | 2006-01-15 |
| ES2299702T3 (en) | 2008-06-01 |
| CN1319938C (en) | 2007-06-06 |
| NO20045353L (en) | 2005-01-20 |
| EP1517883B8 (en) | 2008-05-21 |
| AU2003240099B2 (en) | 2007-02-01 |
| DK1517883T3 (en) | 2008-05-26 |
| DE60319084D1 (en) | 2008-03-27 |
| JP2006182782A (en) | 2006-07-13 |
| US20050256198A1 (en) | 2005-11-17 |
| EP1517883A1 (en) | 2005-03-30 |
| JP3782818B2 (en) | 2006-06-07 |
| MXPA04012686A (en) | 2005-03-23 |
| KR20050014013A (en) | 2005-02-05 |
| TW200409747A (en) | 2004-06-16 |
| US7355069B2 (en) | 2008-04-08 |
| HK1073838A1 (en) | 2005-10-21 |
| EP1517883B1 (en) | 2008-02-13 |
| AR039713A1 (en) | 2005-03-09 |
| CA2489834A1 (en) | 2003-12-31 |
| CN1675171A (en) | 2005-09-28 |
| BR0311932A (en) | 2005-03-22 |
| PT1517883E (en) | 2008-04-21 |
| JP2005529970A (en) | 2005-10-06 |
| WO2004000790A1 (en) | 2003-12-31 |
| DE60319084T2 (en) | 2009-01-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| REFS | Decisions on refusal to grant patents (taken after the publication of the particulars of the applications) |