DK1384717T3 - 2-(2'Triphenylmethyl-2'H-tetrazol-5'-yl)phenylboronsyre som mellemprodukter til syntese af AII receptorantagonister - Google Patents
2-(2'Triphenylmethyl-2'H-tetrazol-5'-yl)phenylboronsyre som mellemprodukter til syntese af AII receptorantagonisterInfo
- Publication number
- DK1384717T3 DK1384717T3 DK03018662T DK03018662T DK1384717T3 DK 1384717 T3 DK1384717 T3 DK 1384717T3 DK 03018662 T DK03018662 T DK 03018662T DK 03018662 T DK03018662 T DK 03018662T DK 1384717 T3 DK1384717 T3 DK 1384717T3
- Authority
- DK
- Denmark
- Prior art keywords
- triphenylmethyl
- tetrazol
- intermediates
- synthesis
- receptor antagonists
- Prior art date
Links
- HXITXNWTGFUOAU-UHFFFAOYSA-N phenylboronic acid Chemical compound OB(O)C1=CC=CC=C1 HXITXNWTGFUOAU-UHFFFAOYSA-N 0.000 title 2
- 230000015572 biosynthetic process Effects 0.000 title 1
- 239000000543 intermediate Substances 0.000 title 1
- 239000002464 receptor antagonist Substances 0.000 title 1
- 229940044551 receptor antagonist Drugs 0.000 title 1
- 238000003786 synthesis reaction Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
- C07F5/05—Cyclic compounds having at least one ring containing boron but no carbon in the ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
- C07F5/025—Boronic and borinic acid compounds
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/793,514 US5130439A (en) | 1991-11-18 | 1991-11-18 | Tetrazolylphenylboronic acid intermediates for the synthesis of AII receptor antagonists |
US07/911,813 US5206374A (en) | 1991-11-18 | 1992-07-10 | Process for preparing tetrazolylphenylboronic acid intermediates |
US07/911,812 US5310928A (en) | 1991-11-18 | 1992-07-10 | Process for preparing biphenyltetrazole compounds |
PCT/US1992/009979 WO1993010106A1 (en) | 1991-11-18 | 1992-11-18 | Tetrazolylphenylboronic acid intermediates for the synthesis of aii receptor antagonists |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1384717T3 true DK1384717T3 (da) | 2008-09-08 |
Family
ID=27121398
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK03018662T DK1384717T3 (da) | 1991-11-18 | 1992-11-18 | 2-(2'Triphenylmethyl-2'H-tetrazol-5'-yl)phenylboronsyre som mellemprodukter til syntese af AII receptorantagonister |
Country Status (3)
Country | Link |
---|---|
US (1) | US5206374A (da) |
DK (1) | DK1384717T3 (da) |
ES (1) | ES2306829T3 (da) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE4319041A1 (de) * | 1992-10-23 | 1994-04-28 | Bayer Ag | Trisubstituierte Biphenyle |
CA2179067A1 (en) * | 1993-12-23 | 1995-06-29 | Gordon Creston Campbell, Jr. | Polymorphs of losartan and the process for the preparation of form ii of losartan |
CN1101393C (zh) * | 1996-10-29 | 2003-02-12 | 麦克公司 | 芦沙坦的结晶方法 |
HU222773B1 (hu) * | 2000-04-21 | 2003-10-28 | Richter Gedeon Vegyészeti Gyár Rt. | Eljárás egy ismert tetrazolszármazék előállítására |
EP1458693A4 (en) * | 2001-11-14 | 2005-02-09 | Teva Pharma | Amorphous and crystalline forms of losartan potassium and method for making same |
CA2482857A1 (en) * | 2002-04-29 | 2003-11-13 | Teva Pharmaceutical Industries Ltd. | Processes for preparing losartan and losartan potassium |
GB0402262D0 (en) * | 2004-02-02 | 2004-03-10 | Novartis Ag | Process for the manufacture of organic compounds |
US20070026026A1 (en) * | 2005-08-01 | 2007-02-01 | David Delmarre | Oral liquid losartan compositions |
WO2008058402A1 (en) | 2006-11-17 | 2008-05-22 | Queen's University At Kingston | Compounds and methods for treating protein folding disorders |
CN101475564B (zh) * | 2009-01-22 | 2012-05-23 | 江苏德峰药业有限公司 | 一种氯沙坦钾的制备方法 |
WO2018002673A1 (en) | 2016-07-01 | 2018-01-04 | N4 Pharma Uk Limited | Novel formulations of angiotensin ii receptor antagonists |
CN108047208B (zh) * | 2018-01-12 | 2022-03-22 | 浙江华海药业股份有限公司 | 一种降低氯沙坦二聚物杂质的方法 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH530980A (de) * | 1969-03-05 | 1972-11-30 | Sandoz Ag | Verfahren zur Herstellung von Imidazo(2,1-a)isoindolen |
US4820843A (en) * | 1987-05-22 | 1989-04-11 | E. I. Du Pont De Nemours And Company | Tetrazole intermediates to antihypertensive compounds |
US5039814A (en) * | 1990-05-02 | 1991-08-13 | Merck & Co., Inc. | Ortho-lithiation process for the synthesis of 2-substituted 1-(tetrazol-5-yl)benzenes |
GB9017480D0 (en) * | 1990-08-09 | 1990-09-26 | Ici Plc | Chemical process |
GB9017482D0 (en) * | 1990-08-09 | 1990-09-26 | Ici Plc | Manufacturing process |
-
1992
- 1992-07-10 US US07/911,813 patent/US5206374A/en not_active Expired - Lifetime
- 1992-11-18 ES ES03018662T patent/ES2306829T3/es not_active Expired - Lifetime
- 1992-11-18 DK DK03018662T patent/DK1384717T3/da active
Also Published As
Publication number | Publication date |
---|---|
US5206374A (en) | 1993-04-27 |
ES2306829T3 (es) | 2008-11-16 |
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