BG99863A - Antagonists of fibrogenous receptor - Google Patents
Antagonists of fibrogenous receptorInfo
- Publication number
- BG99863A BG99863A BG99863A BG9986395A BG99863A BG 99863 A BG99863 A BG 99863A BG 99863 A BG99863 A BG 99863A BG 9986395 A BG9986395 A BG 9986395A BG 99863 A BG99863 A BG 99863A
- Authority
- BG
- Bulgaria
- Prior art keywords
- receptor
- fibrogenous
- antagonists
- compounds
- formula
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/164—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- A61K38/166—Streptokinase
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/49—Urokinase; Tissue plasminogen activator
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
Abstract
Съединенията притежават антагонистична активност по отношение на фибриногеновия рецептор. Те имат формула или напримерThe compounds have antagonistic activity with respect to the fibrinogen receptor. They have a formula or for example
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US2051793A | 1993-02-22 | 1993-02-22 | |
PCT/US1994/001881 WO1994018981A1 (en) | 1993-02-22 | 1994-02-22 | Fibrinogen receptor antagonists |
Publications (1)
Publication Number | Publication Date |
---|---|
BG99863A true BG99863A (en) | 1996-02-29 |
Family
ID=21799049
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BG99863A BG99863A (en) | 1993-02-22 | 1995-08-15 | Antagonists of fibrogenous receptor |
Country Status (15)
Country | Link |
---|---|
EP (1) | EP0684823A4 (en) |
JP (1) | JP3173792B2 (en) |
KR (1) | KR960700722A (en) |
CN (1) | CN1118139A (en) |
AU (1) | AU680240B2 (en) |
BG (1) | BG99863A (en) |
CA (1) | CA2155123A1 (en) |
CZ (1) | CZ210895A3 (en) |
FI (1) | FI953916A0 (en) |
HU (1) | HUT71796A (en) |
NO (1) | NO953270L (en) |
NZ (1) | NZ262664A (en) |
PL (1) | PL310386A1 (en) |
SK (1) | SK102495A3 (en) |
WO (1) | WO1994018981A1 (en) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5849736A (en) * | 1993-11-24 | 1998-12-15 | The Dupont Merck Pharmaceutical Company | Isoxazoline and isoxazole fibrinogen receptor antagonists |
US5494921A (en) * | 1994-09-16 | 1996-02-27 | Merck & Co., Inc. | Fibrinogen receptor antagonists |
ZA963391B (en) * | 1995-05-24 | 1997-10-29 | Du Pont Merck Pharma | Isoxazoline fibrinogen receptor antagonists. |
CN1085980C (en) * | 1995-08-30 | 2002-06-05 | G·D·瑟尔公司 | meta-guanidine, urea, thiourea or azacyclic amino benzoic acid derivatives as integrin antagonists |
US6100423A (en) * | 1995-08-30 | 2000-08-08 | G. D. Searle & Co. | Amino benzenepropanoic acid compounds and derivatives thereof |
CA2233204A1 (en) | 1995-09-29 | 1997-04-03 | Joseph A. Jakubowski | Spiro compounds as inhibitors of fibrinogen-dependent platelet aggregation |
JP2000501105A (en) * | 1995-12-22 | 2000-02-02 | デュポン ファーマシューティカルズ カンパニー | Novel integrin receptor antagonist |
WO1997035579A1 (en) * | 1996-03-27 | 1997-10-02 | Merck & Co., Inc. | A method for inhibiting clot formation |
ES2271971T3 (en) * | 1996-07-25 | 2007-04-16 | Biogen Idec Ma Inc. | INHIBITORS OF CELL ADHESION. |
US5900414A (en) * | 1996-08-29 | 1999-05-04 | Merck & Co., Inc. | Methods for administering integrin receptor antagonists |
DE19653647A1 (en) * | 1996-12-20 | 1998-06-25 | Hoechst Ag | Vitronectin receptor antagonists, their preparation and their use |
CA2279927A1 (en) * | 1997-02-06 | 1998-08-13 | Merck & Co., Inc. | Fibrinogen receptor antagonist prodrugs |
US6214834B1 (en) | 1997-03-28 | 2001-04-10 | Dupont Pharmaceuticals Company | Integrin inhibitor prodrugs |
US6303625B1 (en) * | 1998-07-27 | 2001-10-16 | Ortho-Mcneil Pharmaceutical, Inc. | Triazolopyridines for the treatment of thrombosis disorders |
AU773227B2 (en) * | 1999-07-28 | 2004-05-20 | Aventis Pharmaceuticals Inc. | Substituted oxoazaheterocyclyl compounds |
CA2510298A1 (en) * | 2002-12-20 | 2004-07-15 | Pharmacia Corporation | Acyclic pyrazole compounds |
AU2007272009A1 (en) * | 2006-07-12 | 2008-01-17 | Syngenta Limited | Triazolopyridine derivatives as herbicides |
KR20100132999A (en) * | 2008-04-04 | 2010-12-20 | 길리애드 사이언시즈, 인코포레이티드 | Triazolopyridinone derivatives for use as stearoyl coa desaturase inhibitors |
WO2010096722A1 (en) * | 2009-02-20 | 2010-08-26 | Takeda Pharmaceutical Company Limited | 3-oxo-2, 3-dihydro- [1,2, 4] triazolo [4, 3-a]pyridines as soluble epoxide hydrolase (seh) inhibitors |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5084466A (en) * | 1989-01-31 | 1992-01-28 | Hoffmann-La Roche Inc. | Novel carboxamide pyridine compounds which have useful pharmaceutical utility |
GB8913011D0 (en) * | 1989-06-06 | 1989-07-26 | Wellcome Found | Anticonvulsant pyrazines |
US5166154A (en) * | 1989-10-17 | 1992-11-24 | Boehringer Ingelheim Pharmaceuticals, Inc. | Imidazo[1,2-a]piperazines |
US5278161A (en) * | 1990-06-28 | 1994-01-11 | Hoffmann-La Roche Inc. | Amino acid derivatives useful as renin inhibitors |
-
1994
- 1994-02-22 NZ NZ262664A patent/NZ262664A/en unknown
- 1994-02-22 JP JP51922094A patent/JP3173792B2/en not_active Expired - Fee Related
- 1994-02-22 PL PL94310386A patent/PL310386A1/en unknown
- 1994-02-22 EP EP94909745A patent/EP0684823A4/en not_active Withdrawn
- 1994-02-22 HU HU9502028A patent/HUT71796A/en unknown
- 1994-02-22 WO PCT/US1994/001881 patent/WO1994018981A1/en not_active Application Discontinuation
- 1994-02-22 CA CA002155123A patent/CA2155123A1/en not_active Abandoned
- 1994-02-22 AU AU62465/94A patent/AU680240B2/en not_active Ceased
- 1994-02-22 CN CN94191248A patent/CN1118139A/en active Pending
- 1994-02-22 SK SK1024-95A patent/SK102495A3/en unknown
- 1994-02-22 CZ CZ952108A patent/CZ210895A3/en unknown
-
1995
- 1995-08-15 BG BG99863A patent/BG99863A/en unknown
- 1995-08-21 FI FI953916A patent/FI953916A0/en not_active Application Discontinuation
- 1995-08-21 NO NO953270A patent/NO953270L/en unknown
- 1995-08-21 KR KR1019950703563A patent/KR960700722A/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
PL310386A1 (en) | 1995-12-11 |
NZ262664A (en) | 1997-04-24 |
JPH08507072A (en) | 1996-07-30 |
CZ210895A3 (en) | 1996-02-14 |
JP3173792B2 (en) | 2001-06-04 |
EP0684823A4 (en) | 1997-07-09 |
KR960700722A (en) | 1996-02-24 |
NO953270D0 (en) | 1995-08-21 |
AU680240B2 (en) | 1997-07-24 |
HUT71796A (en) | 1996-02-28 |
FI953916A (en) | 1995-08-21 |
FI953916A0 (en) | 1995-08-21 |
AU6246594A (en) | 1994-09-14 |
CN1118139A (en) | 1996-03-06 |
NO953270L (en) | 1995-10-19 |
CA2155123A1 (en) | 1994-09-01 |
EP0684823A1 (en) | 1995-12-06 |
WO1994018981A1 (en) | 1994-09-01 |
HU9502028D0 (en) | 1995-09-28 |
SK102495A3 (en) | 1997-01-08 |
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