DK137955B - Analogifremgangsmåde til fremstilling af morphinan-derivater. - Google Patents

Analogifremgangsmåde til fremstilling af morphinan-derivater.

Info

Publication number
DK137955B
DK137955B DK300571AA DK300571A DK137955B DK 137955 B DK137955 B DK 137955B DK 300571A A DK300571A A DK 300571AA DK 300571 A DK300571 A DK 300571A DK 137955 B DK137955 B DK 137955B
Authority
DK
Denmark
Prior art keywords
preparation
analogous process
morphinan derivatives
morphinan
derivatives
Prior art date
Application number
DK300571AA
Other languages
Danish (da)
English (en)
Other versions
DK137955C (de
Inventor
Masuo Murakami
Shigemi Kawahara
Noriyoshi Inukai
Noriaki Nagano
Hidenori Iwamoto
Hisashi Ida
Original Assignee
Yamanouchi Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP394571A external-priority patent/JPS5314558B1/ja
Application filed by Yamanouchi Pharma Co Ltd filed Critical Yamanouchi Pharma Co Ltd
Publication of DK137955B publication Critical patent/DK137955B/da
Application granted granted Critical
Publication of DK137955C publication Critical patent/DK137955C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/18Aralkyl radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/24Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D221/00Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22Bridged ring systems
    • C07D221/28Morphinans

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Paper (AREA)
DK300571AA 1970-06-20 1971-06-18 Analogifremgangsmåde til fremstilling af morphinan-derivater. DK137955B (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP5391870 1970-06-20
JP394571A JPS5314558B1 (de) 1971-02-02 1971-02-02
JP541371 1971-02-09

Publications (2)

Publication Number Publication Date
DK137955B true DK137955B (da) 1978-06-12
DK137955C DK137955C (de) 1978-11-06

Family

ID=27276046

Family Applications (1)

Application Number Title Priority Date Filing Date
DK300571AA DK137955B (da) 1970-06-20 1971-06-18 Analogifremgangsmåde til fremstilling af morphinan-derivater.

Country Status (10)

Country Link
US (1) US3786054A (de)
BE (1) BE768710A (de)
CA (1) CA919668A (de)
DE (1) DE2128607C3 (de)
DK (1) DK137955B (de)
ES (1) ES392421A1 (de)
FR (1) FR2100799B1 (de)
GB (1) GB1301243A (de)
NO (2) NO132279C (de)
SE (1) SE386894B (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1406882A (en) * 1972-04-28 1975-09-17 Leo Pharm Prod Ltd Benzoic acid derivatives and benzisptjoaup'e 1.1 dopxode derovatoves
US3919237A (en) * 1972-07-07 1975-11-11 Hoffmann La Roche Preparation of isomorphinan derivative
JPS52136176A (en) * 1976-03-23 1977-11-14 Bristol Myers Co Method of improving 144hydroxymorphinan derivatives
US4058531A (en) * 1976-03-23 1977-11-15 Bristol-Myers Company Process for the preparation of 14-hydroxymorphinan derivatives
EP2987788A1 (de) 2002-05-17 2016-02-24 Taiwanj Pharmaceuticals Co., Ltd. Opioid und opioidähnliche verbindungen und verwendung davon
CN101993417B (zh) * 2009-08-10 2014-09-24 北京利乐生制药科技有限公司 磷酸二甲啡烷的稳定晶型
CN102241630A (zh) * 2011-05-20 2011-11-16 杭州保灵集团有限公司 一种镇咳嗽药磷酸二甲啡烷的制备方法
CN103288731A (zh) * 2013-06-03 2013-09-11 四川百利药业有限责任公司 一种磷酸二甲啡烷中间体的制备方法
CN108299301A (zh) * 2018-03-12 2018-07-20 合肥医工医药有限公司 一种制备高纯度二甲啡烷的方法
CN108484502A (zh) * 2018-03-12 2018-09-04 合肥医工医药有限公司 一种制备磷酸二甲啡烷的方法
CN108383788A (zh) * 2018-03-27 2018-08-10 合肥医工医药有限公司 一种二甲啡烷异构体的制备方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1093029A (fr) * 1952-12-08 1955-04-29 Hoffmann La Roche Procédé pour la préparation de dérivés de morphinane

Also Published As

Publication number Publication date
FR2100799B1 (de) 1975-01-17
ES392421A1 (es) 1974-07-16
FR2100799A1 (de) 1972-03-24
NO132279B (de) 1975-07-07
NO141161C (no) 1980-01-23
CA919668A (en) 1973-01-23
NO141161B (no) 1979-10-15
DK137955C (de) 1978-11-06
DE2128607C3 (de) 1980-10-02
DE2128607B2 (de) 1980-02-07
GB1301243A (de) 1972-12-29
NO132279C (de) 1975-10-15
BE768710A (fr) 1971-11-03
NO750529L (de) 1971-12-21
US3786054A (en) 1974-01-15
DE2128607A1 (de) 1971-12-30
SE386894B (sv) 1976-08-23

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Legal Events

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PUP Patent expired