BE768710A - Procede de preparation de nouveaux derives de la morphiname - Google Patents

Procede de preparation de nouveaux derives de la morphiname

Info

Publication number
BE768710A
BE768710A BE768710A BE768710A BE768710A BE 768710 A BE768710 A BE 768710A BE 768710 A BE768710 A BE 768710A BE 768710 A BE768710 A BE 768710A BE 768710 A BE768710 A BE 768710A
Authority
BE
Belgium
Prior art keywords
morphiname
new derivatives
preparing new
preparing
derivatives
Prior art date
Application number
BE768710A
Other languages
English (en)
French (fr)
Inventor
M Murakami
S Kawahara
N Inukai
N Nagano
H Iwamoto
Original Assignee
Yamanouchi Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP394571A external-priority patent/JPS5314558B1/ja
Application filed by Yamanouchi Pharma Co Ltd filed Critical Yamanouchi Pharma Co Ltd
Publication of BE768710A publication Critical patent/BE768710A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/18—Aralkyl radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/24—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22—Bridged ring systems
    • C07D221/28—Morphinans

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Paper (AREA)
BE768710A 1970-06-20 1971-06-18 Procede de preparation de nouveaux derives de la morphiname BE768710A (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP5391870 1970-06-20
JP394571A JPS5314558B1 (xx) 1971-02-02 1971-02-02
JP541371 1971-02-09

Publications (1)

Publication Number Publication Date
BE768710A true BE768710A (fr) 1971-11-03

Family

ID=27276046

Family Applications (1)

Application Number Title Priority Date Filing Date
BE768710A BE768710A (fr) 1970-06-20 1971-06-18 Procede de preparation de nouveaux derives de la morphiname

Country Status (10)

Country Link
US (1) US3786054A (xx)
BE (1) BE768710A (xx)
CA (1) CA919668A (xx)
DE (1) DE2128607C3 (xx)
DK (1) DK137955B (xx)
ES (1) ES392421A1 (xx)
FR (1) FR2100799B1 (xx)
GB (1) GB1301243A (xx)
NO (2) NO132279C (xx)
SE (1) SE386894B (xx)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102241630A (zh) * 2011-05-20 2011-11-16 杭州保灵集团有限公司 一种镇咳嗽药磷酸二甲啡烷的制备方法

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1406882A (en) * 1972-04-28 1975-09-17 Leo Pharm Prod Ltd Benzoic acid derivatives and benzisptjoaup'e 1.1 dopxode derovatoves
US3919237A (en) * 1972-07-07 1975-11-11 Hoffmann La Roche Preparation of isomorphinan derivative
JPS52136176A (en) * 1976-03-23 1977-11-14 Bristol Myers Co Method of improving 144hydroxymorphinan derivatives
US4058531A (en) * 1976-03-23 1977-11-15 Bristol-Myers Company Process for the preparation of 14-hydroxymorphinan derivatives
EP2987788A1 (en) 2002-05-17 2016-02-24 Taiwanj Pharmaceuticals Co., Ltd. Opioid and opioid-like compounds and uses thereof
CN101993417B (zh) * 2009-08-10 2014-09-24 北京利乐生制药科技有限公司 磷酸二甲啡烷的稳定晶型
CN103288731A (zh) * 2013-06-03 2013-09-11 四川百利药业有限责任公司 一种磷酸二甲啡烷中间体的制备方法
CN108299301A (zh) * 2018-03-12 2018-07-20 合肥医工医药有限公司 一种制备高纯度二甲啡烷的方法
CN108484502A (zh) * 2018-03-12 2018-09-04 合肥医工医药有限公司 一种制备磷酸二甲啡烷的方法
CN108383788A (zh) * 2018-03-27 2018-08-10 合肥医工医药有限公司 一种二甲啡烷异构体的制备方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1093029A (fr) * 1952-12-08 1955-04-29 Hoffmann La Roche Procédé pour la préparation de dérivés de morphinane

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102241630A (zh) * 2011-05-20 2011-11-16 杭州保灵集团有限公司 一种镇咳嗽药磷酸二甲啡烷的制备方法

Also Published As

Publication number Publication date
FR2100799B1 (xx) 1975-01-17
ES392421A1 (es) 1974-07-16
FR2100799A1 (xx) 1972-03-24
NO132279B (xx) 1975-07-07
NO141161C (no) 1980-01-23
CA919668A (en) 1973-01-23
NO141161B (no) 1979-10-15
DK137955C (xx) 1978-11-06
DE2128607C3 (de) 1980-10-02
DE2128607B2 (de) 1980-02-07
GB1301243A (xx) 1972-12-29
NO132279C (xx) 1975-10-15
DK137955B (da) 1978-06-12
NO750529L (xx) 1971-12-21
US3786054A (en) 1974-01-15
DE2128607A1 (de) 1971-12-30
SE386894B (sv) 1976-08-23

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Legal Events

Date Code Title Description
RE20 Patent expired

Owner name: YAMANOUCHI PHARMACEUTICAL CO. LTD

Effective date: 19910618