DK1368348T3 - Hidtil ukendte 2,5-diazabicyclo[2.2.1]heptanderivater - Google Patents
Hidtil ukendte 2,5-diazabicyclo[2.2.1]heptanderivaterInfo
- Publication number
- DK1368348T3 DK1368348T3 DK02700189T DK02700189T DK1368348T3 DK 1368348 T3 DK1368348 T3 DK 1368348T3 DK 02700189 T DK02700189 T DK 02700189T DK 02700189 T DK02700189 T DK 02700189T DK 1368348 T3 DK1368348 T3 DK 1368348T3
- Authority
- DK
- Denmark
- Prior art keywords
- diseases
- disorders
- diazabicyclo
- heptane derivatives
- nervous system
- Prior art date
Links
- UKHJNJFJCGBKSF-UHFFFAOYSA-N 2,5-diazabicyclo[2.2.1]heptane Chemical class C1NC2CNC1C2 UKHJNJFJCGBKSF-UHFFFAOYSA-N 0.000 title abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 8
- 201000010099 disease Diseases 0.000 abstract 4
- 208000035475 disorder Diseases 0.000 abstract 4
- 210000003169 central nervous system Anatomy 0.000 abstract 2
- 210000001428 peripheral nervous system Anatomy 0.000 abstract 2
- 208000017701 Endocrine disease Diseases 0.000 abstract 1
- 206010061218 Inflammation Diseases 0.000 abstract 1
- 208000002193 Pain Diseases 0.000 abstract 1
- 208000007271 Substance Withdrawal Syndrome Diseases 0.000 abstract 1
- 230000001713 cholinergic effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 208000030172 endocrine system disease Diseases 0.000 abstract 1
- 230000004054 inflammatory process Effects 0.000 abstract 1
- 230000004770 neurodegeneration Effects 0.000 abstract 1
- 230000000144 pharmacologic effect Effects 0.000 abstract 1
- 230000003389 potentiating effect Effects 0.000 abstract 1
- 230000016160 smooth muscle contraction Effects 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/08—Bridged systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4995—Pyrazines or piperazines forming part of bridged ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Epidemiology (AREA)
- Child & Adolescent Psychology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Hospice & Palliative Care (AREA)
- Psychology (AREA)
- Obesity (AREA)
- Anesthesiology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA200100344 | 2001-03-02 | ||
| PCT/DK2002/000133 WO2002070522A1 (en) | 2001-03-02 | 2002-02-28 | Novel 2,5-diazabicyclo[2.2.1]heptane derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1368348T3 true DK1368348T3 (da) | 2005-05-23 |
Family
ID=8160337
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK02700189T DK1368348T3 (da) | 2001-03-02 | 2002-02-28 | Hidtil ukendte 2,5-diazabicyclo[2.2.1]heptanderivater |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US7329754B2 (enExample) |
| EP (1) | EP1368348B1 (enExample) |
| JP (1) | JP4294958B2 (enExample) |
| CN (1) | CN1331864C (enExample) |
| AT (1) | ATE287404T1 (enExample) |
| AU (1) | AU2002233181B2 (enExample) |
| CA (1) | CA2438815A1 (enExample) |
| DE (1) | DE60202667T2 (enExample) |
| DK (1) | DK1368348T3 (enExample) |
| MX (1) | MXPA03007895A (enExample) |
| NZ (1) | NZ527006A (enExample) |
| WO (1) | WO2002070522A1 (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7084156B2 (en) | 2001-11-27 | 2006-08-01 | Merck & Co., Inc. | 2-Aminoquinoline compounds |
| BRPI0908807A2 (pt) * | 2008-02-15 | 2015-07-28 | Hoffmann La Roche | Derivados de 3-alquil-piperazina e usos dos mesmos |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IN166416B (enExample) * | 1985-09-18 | 1990-05-05 | Pfizer | |
| US5196548A (en) * | 1989-05-11 | 1993-03-23 | Pfizer Inc. | Preparation of diazabicyclic Intermediates |
| JPH06228138A (ja) * | 1993-02-03 | 1994-08-16 | Fujisawa Pharmaceut Co Ltd | ピリドシンノリン化合物またはその塩及びこれを含有する抗菌剤 |
| US5478939A (en) * | 1994-07-20 | 1995-12-26 | American Cyanamid Company | (R,R) and (S,S) 2,5-diazabicyclo [2,2,1]heptane derivatives |
| US5561127A (en) * | 1994-12-19 | 1996-10-01 | Allelix Biopharmaceuticals, Inc. | Muscarinic receptor ligands |
| FR2786769B1 (fr) | 1998-12-04 | 2002-10-25 | Synthelabo | Derives de 2,5-diazabicyclo[2.2.1]heptane, leur preparation et leur application en therapeutique |
| DE60006213T2 (de) * | 1999-01-29 | 2004-07-29 | Abbott Laboratories, Abbott Park | Diazabicyloderivate als nikotin-acetylcholin-rezeptorliganden |
| US6852721B2 (en) * | 2000-05-25 | 2005-02-08 | Targacept, Inc. | Pharmaceutical compositions and methods for use |
| US6552015B2 (en) * | 2000-08-03 | 2003-04-22 | Pfizer Inc. | Azabicycloalkane derivatives and therapeutic uses thereof |
-
2002
- 2002-02-28 CA CA002438815A patent/CA2438815A1/en not_active Abandoned
- 2002-02-28 WO PCT/DK2002/000133 patent/WO2002070522A1/en not_active Ceased
- 2002-02-28 AT AT02700189T patent/ATE287404T1/de not_active IP Right Cessation
- 2002-02-28 JP JP2002569842A patent/JP4294958B2/ja not_active Expired - Fee Related
- 2002-02-28 US US10/250,765 patent/US7329754B2/en not_active Expired - Fee Related
- 2002-02-28 NZ NZ527006A patent/NZ527006A/en unknown
- 2002-02-28 DK DK02700189T patent/DK1368348T3/da active
- 2002-02-28 MX MXPA03007895A patent/MXPA03007895A/es active IP Right Grant
- 2002-02-28 AU AU2002233181A patent/AU2002233181B2/en not_active Ceased
- 2002-02-28 DE DE60202667T patent/DE60202667T2/de not_active Expired - Lifetime
- 2002-02-28 CN CNB028050770A patent/CN1331864C/zh not_active Expired - Fee Related
- 2002-02-28 EP EP02700189A patent/EP1368348B1/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| MXPA03007895A (es) | 2003-12-04 |
| DE60202667T2 (de) | 2005-06-16 |
| CN1331864C (zh) | 2007-08-15 |
| NZ527006A (en) | 2005-02-25 |
| DE60202667D1 (de) | 2005-02-24 |
| HK1068878A1 (en) | 2005-05-06 |
| EP1368348B1 (en) | 2005-01-19 |
| AU2002233181B2 (en) | 2007-06-07 |
| ATE287404T1 (de) | 2005-02-15 |
| CA2438815A1 (en) | 2002-09-12 |
| CN1535273A (zh) | 2004-10-06 |
| US20040181069A1 (en) | 2004-09-16 |
| EP1368348A1 (en) | 2003-12-10 |
| JP2004529901A (ja) | 2004-09-30 |
| JP4294958B2 (ja) | 2009-07-15 |
| WO2002070522A1 (en) | 2002-09-12 |
| US7329754B2 (en) | 2008-02-12 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IS7742A (is) | Nýjar kvínúklidín-afleiður og notkun þeirra | |
| DK1551835T3 (da) | Hidtil ukendte 1,4-diazabicycloalkanderivater, deres fremstilling og anvendelse | |
| ATE385497T1 (de) | 3-substituierte quinuclidin-derivate und deren verwendung als nikotinischen agonisten | |
| DK1506200T3 (da) | Diazabicykliske biarylderivater | |
| AU6583101A (en) | Aryl and heteroaryl diazabicycloalkanes, their preparation and use | |
| DK1562945T3 (da) | Hidtil ukendte diazebicykliske biarylderivater | |
| ATE289310T1 (de) | Heteroaryl-diazabicycloalkanderivaten als cns- modulatoren | |
| DK1406900T3 (da) | Hidtil ukendte forbindelser, fremstilling og anvendelse deraf | |
| ATE289607T1 (de) | Neue heteroaryl-diazabizykloalkane | |
| ATE445618T1 (de) | Neue diazabicyclische arylderivate | |
| ATE437880T1 (de) | Dimere azacyclische verbindungen und deren verwendung | |
| DE60307102D1 (de) | 3-substituierte chinuklidine und deren verwendung | |
| DE60322212D1 (de) | Neue azacyclische ethinylderivate | |
| DK1368348T3 (da) | Hidtil ukendte 2,5-diazabicyclo[2.2.1]heptanderivater | |
| DE602004031124D1 (de) | Neue chinuklidinderivative und deren pharmazeutische verwendung |