DK135808B - Analogifremgangsmåde til fremstilling af benzo(b)thiophen-derivater eller syreadditionssalte deraf. - Google Patents

Analogifremgangsmåde til fremstilling af benzo(b)thiophen-derivater eller syreadditionssalte deraf.

Info

Publication number
DK135808B
DK135808B DK251975AA DK251975A DK135808B DK 135808 B DK135808 B DK 135808B DK 251975A A DK251975A A DK 251975AA DK 251975 A DK251975 A DK 251975A DK 135808 B DK135808 B DK 135808B
Authority
DK
Denmark
Prior art keywords
benzo
preparation
acid addition
addition salts
thiophene derivatives
Prior art date
Application number
DK251975AA
Other languages
Danish (da)
English (en)
Other versions
DK251975A (fr
DK135808C (fr
Inventor
Marcel Descamps
Jean Gubin
Original Assignee
Labaz
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Labaz filed Critical Labaz
Publication of DK251975A publication Critical patent/DK251975A/da
Publication of DK135808B publication Critical patent/DK135808B/da
Application granted granted Critical
Publication of DK135808C publication Critical patent/DK135808C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/56—Radicals substituted by oxygen atoms
DK251975AA 1974-06-06 1975-06-04 Analogifremgangsmåde til fremstilling af benzo(b)thiophen-derivater eller syreadditionssalte deraf. DK135808B (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB2525674A GB1456323A (en) 1974-06-06 1974-06-06 Benzothiophenes process for preparing them and pharmaceutical compositions containing the same

Publications (3)

Publication Number Publication Date
DK251975A DK251975A (fr) 1975-12-07
DK135808B true DK135808B (da) 1977-06-27
DK135808C DK135808C (fr) 1977-11-28

Family

ID=10224753

Family Applications (1)

Application Number Title Priority Date Filing Date
DK251975AA DK135808B (da) 1974-06-06 1975-06-04 Analogifremgangsmåde til fremstilling af benzo(b)thiophen-derivater eller syreadditionssalte deraf.

Country Status (20)

Country Link
US (1) US4007204A (fr)
JP (1) JPS516958A (fr)
AR (2) AR207152A1 (fr)
AT (1) AT341517B (fr)
BE (1) BE829837A (fr)
CA (1) CA1030972A (fr)
CH (1) CH605910A5 (fr)
DE (1) DE2522655A1 (fr)
DK (1) DK135808B (fr)
ES (1) ES438303A1 (fr)
FI (1) FI751602A (fr)
GB (1) GB1456323A (fr)
HU (1) HU172820B (fr)
IT (1) IT1038094B (fr)
NL (1) NL7504921A (fr)
NO (1) NO751989L (fr)
OA (1) OA05022A (fr)
SE (1) SE7505482L (fr)
SU (1) SU578002A3 (fr)
ZA (1) ZA752871B (fr)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU509682B2 (en) * 1975-10-28 1980-05-22 Eli Lilly And Company 2-Aroyl-3-Phenylbenzothiophene Derivatives
US4133814A (en) * 1975-10-28 1979-01-09 Eli Lilly And Company 2-Phenyl-3-aroylbenzothiophenes useful as antifertility agents
US5175184A (en) * 1982-10-19 1992-12-29 Kotobuki Seiyaku Company Limited Benzothiophene derivatives and antihyperuricemia thereof
NO174506B (no) * 1984-10-30 1994-02-07 Usv Pharma Corp Analogifremgangsmaate ved fremstilling av terapeutisk aktive forbindelser
US4851554A (en) * 1987-04-06 1989-07-25 University Of Tennessee Research Corporation Certain 3-substituted 2-alkyl benzofuran derivatives
US4806663A (en) * 1987-04-06 1989-02-21 The University Of Tennessee Research Corporation Certain 3-substituted 2-alkyl benzofuran derivatives
US4912642A (en) * 1987-09-03 1990-03-27 The Boeing Company Coordinated engine autothrottle
US4831156A (en) * 1987-09-30 1989-05-16 The University Of Tennessee Research Corp. 3-substituted 2-alkyl indole derivatives
WO1989002893A1 (fr) * 1987-09-30 1989-04-06 The University Of Tennessee Research Corporation Derives d'alkyle-2 benzothiophenes substitues en position 3
JP3157882B2 (ja) * 1991-11-15 2001-04-16 帝国臓器製薬株式会社 新規なベンゾチオフエン誘導体
AU683552B2 (en) * 1994-04-11 1997-11-13 Chugai Seiyaku Kabushiki Kaisha 4,6-DI-t-butyl-2,3-dihydrobenzothiophene derivative
CO4410191A1 (es) * 1994-09-19 1997-01-09 Lilly Co Eli SINTESIS DE 3-[4-(2-AMINOETOXI)BENZOIL]-2-ARIL-6- HIDROXIBENZO [b] TIOFENOS
US6653328B1 (en) * 1995-03-10 2003-11-25 Eli Lilly And Company 3-benzyl-benzothiophenes
US6417199B1 (en) * 1995-03-10 2002-07-09 Eli Lilly And Company 3-benzyl-benzothiophenes
JP2002500618A (ja) 1995-10-31 2002-01-08 イーライ・リリー・アンド・カンパニー 抗血栓性ジアミン
JP2000506885A (ja) * 1996-03-19 2000-06-06 イーライ・リリー・アンド・カンパニー ３―［４―（２―アミノエトキシ）ベンゾイル］―２―アリール―６―ヒドロキシベンゾ［ｂ］チオフェンの合成
WO1998049160A1 (fr) 1997-04-30 1998-11-05 Eli Lilly And Company Agents antithrombotiques
AU7170898A (en) 1997-04-30 1998-11-24 Eli Lilly And Company Antithrombotic agents
WO1998049161A1 (fr) 1997-04-30 1998-11-05 Eli Lilly And Company Agents antithrombotiques
CA2287918A1 (fr) * 1997-04-30 1998-11-05 John Mcneill Mcgill Iii Procede d'alkylation regioselective pour la preparation de benzo¬b|thiophenes substitues
CA2288224A1 (fr) 1997-04-30 1998-11-05 Mary George Johnson Agents antithrombotiques
US6284756B1 (en) 1998-04-30 2001-09-04 Eli Lilly And Company Antithrombotic agents
EP0997460B1 (fr) * 1998-10-28 2002-12-11 Eli Lilly And Company Dérivés de benzothiophène comme agents antithrombotiques et produits intermédiaires
FR2864536B1 (fr) * 2003-12-24 2006-03-17 Clariant France Sa Procede de preparation de n-alkyl-2 (hydroxy-4-benzoyl)-3 benzofurannes et intermediaires pour sa mise en oeuvre
US9072745B2 (en) * 2010-08-06 2015-07-07 Tasly Pharmaceutical Group Co., Ltd Use of Salvia miltiorrhiza composition in preparing drugs for secondary prevention of coronary heart disease

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3514465A (en) * 1966-12-30 1970-05-26 Degussa Certain thiazolyl- and pyridinylaminoketones
US3706747A (en) * 1970-06-05 1972-12-19 Pfizer Benzothieno(3,2-d)- and benzofuro(3,2-d)pyrimidines

Also Published As

Publication number Publication date
FI751602A (fr) 1975-12-07
CH605910A5 (fr) 1978-10-13
OA05022A (fr) 1980-12-31
CA1030972A (fr) 1978-05-09
DK251975A (fr) 1975-12-07
DK135808C (fr) 1977-11-28
BE829837A (fr) 1975-12-04
AT341517B (de) 1978-02-10
DE2522655A1 (de) 1975-12-18
ATA431175A (de) 1977-06-15
AU8102275A (en) 1976-11-11
JPS516958A (en) 1976-01-20
AR207152A1 (es) 1976-09-15
ZA752871B (en) 1976-04-28
ES438303A1 (es) 1977-01-16
SU578002A3 (ru) 1977-10-25
SE7505482L (sv) 1975-12-08
NO751989L (fr) 1975-12-09
HU172820B (hu) 1978-12-28
GB1456323A (en) 1976-11-24
AR210265A1 (es) 1977-07-15
NL7504921A (nl) 1975-12-09
US4007204A (en) 1977-02-08
IT1038094B (it) 1979-11-20

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