DK134488B - Analogifremgangsmåde til fremstilling af i stillingerne 4a, 10b cis-konfigurerede benzo/c//1,6/naphthyridinderivater eller syreadditionssalte deraf. - Google Patents
Analogifremgangsmåde til fremstilling af i stillingerne 4a, 10b cis-konfigurerede benzo/c//1,6/naphthyridinderivater eller syreadditionssalte deraf.Info
- Publication number
- DK134488B DK134488B DK225771A DK225771A DK134488B DK 134488 B DK134488 B DK 134488B DK 225771 A DK225771 A DK 225771A DK 225771 A DK225771 A DK 225771A DK 134488 B DK134488 B DK 134488B
- Authority
- DK
- Denmark
- Prior art keywords
- benzo
- cis
- positions
- preparation
- acid addition
- Prior art date
Links
- 239000002253 acid Substances 0.000 title 1
- 125000005605 benzo group Chemical group 0.000 title 1
- 150000005054 naphthyridines Chemical class 0.000 title 1
- 150000003839 salts Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/56—Nitrogen atoms
- C07D211/58—Nitrogen atoms attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
- C07D491/14—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH708970A CH527822A (de) | 1970-05-13 | 1970-05-13 | Verfahren zur Herstellung neuer Benzonaphtyridin-Derivate |
| CH708670A CH527196A (de) | 1970-05-13 | 1970-05-13 | Verfahren zur Herstellung neuer Benzonaphthyridinderivate |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK134488B true DK134488B (da) | 1976-11-15 |
| DK134488C DK134488C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1977-05-16 |
Family
ID=25700728
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK225771A DK134488B (da) | 1970-05-13 | 1971-05-11 | Analogifremgangsmåde til fremstilling af i stillingerne 4a, 10b cis-konfigurerede benzo/c//1,6/naphthyridinderivater eller syreadditionssalte deraf. |
Country Status (14)
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3899494A (en) * | 1970-05-13 | 1975-08-12 | Sandoz Ltd | Substituted 6-phenyl benzo-naphthyridines |
| NL7314396A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * | 1972-10-26 | 1974-05-01 | ||
| BE880455A (fr) * | 1979-01-22 | 1980-06-06 | Sandoz Sa | Compositions pharmaceutiques a base d'une benzo (c) (1,6) naphtyridine |
| AU8106598A (en) * | 1997-06-03 | 1998-12-21 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Benzonaphthyridine |
| ES2260043T3 (es) | 1999-08-21 | 2006-11-01 | Altana Pharma Ag | Combinacion sinergica de roflumilast y salmeterol. |
| US7772188B2 (en) | 2003-01-28 | 2010-08-10 | Ironwood Pharmaceuticals, Inc. | Methods and compositions for the treatment of gastrointestinal disorders |
| US7153824B2 (en) | 2003-04-01 | 2006-12-26 | Applied Research Systems Ars Holding N.V. | Inhibitors of phosphodiesterases in infertility |
| CA2565953A1 (en) * | 2004-05-12 | 2005-11-24 | Pfizer Products Inc. | Piperidine derivatives as nk1 and nk3 antagonists |
| ES2393885T7 (es) | 2007-06-04 | 2014-01-30 | Synergy Pharmaceuticals Inc. | Agonistas de la guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros trastornos |
| US8969514B2 (en) | 2007-06-04 | 2015-03-03 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases |
| CA2726917C (en) | 2008-06-04 | 2018-06-26 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
| AU2009270833B2 (en) | 2008-07-16 | 2015-02-19 | Bausch Health Ireland Limited | Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders |
| US9616097B2 (en) | 2010-09-15 | 2017-04-11 | Synergy Pharmaceuticals, Inc. | Formulations of guanylate cyclase C agonists and methods of use |
| EP3366698A1 (en) | 2011-03-01 | 2018-08-29 | Synergy Pharmaceuticals Inc. | Guanylate cyclase c agonists |
| AU2014218599C1 (en) | 2013-02-25 | 2018-09-06 | Bausch Health Ireland Limited | Guanylate cyclase receptor agonists for use in colonic cleansing |
| US9708367B2 (en) | 2013-03-15 | 2017-07-18 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase and their uses |
| JP2016514670A (ja) | 2013-03-15 | 2016-05-23 | シナジー ファーマシューティカルズ インコーポレイテッド | 他の薬物と組み合わせたグアニル酸シクラーゼ受容体アゴニスト |
| EA201592263A1 (ru) | 2013-06-05 | 2016-05-31 | Синерджи Фармасьютикалз, Инк. | Ультрачистые агонисты гуанилатциклазы c, способ их получения и использования |
| KR102456567B1 (ko) | 2013-08-09 | 2022-10-19 | 알데릭스, 인코포레이티드 | 인산염 수송을 억제하기 위한 화합물 및 방법 |
| EP3972599A1 (en) | 2019-05-21 | 2022-03-30 | Ardelyx, Inc. | Combination for lowering serum phosphate in a patient |
-
1971
- 1971-05-10 GB GB1398471A patent/GB1361441A/en not_active Expired
- 1971-05-11 SU SU1656559A patent/SU423296A3/ru active
- 1971-05-11 DK DK225771A patent/DK134488B/da unknown
- 1971-05-11 ES ES391026A patent/ES391026A1/es not_active Expired
- 1971-05-11 DE DE19712123328 patent/DE2123328A1/de not_active Ceased
- 1971-05-11 PL PL14807271A patent/PL76913B1/pl unknown
- 1971-05-11 CS CS920771A patent/CS167202B2/cs unknown
- 1971-05-11 CS CS341671A patent/CS162753B2/cs unknown
- 1971-05-11 FI FI129371A patent/FI52089C/fi active
- 1971-05-12 FR FR7117124A patent/FR2100649B1/fr not_active Expired
- 1971-05-12 JP JP3189471A patent/JPS5432799B1/ja active Pending
- 1971-05-12 NL NL7106502A patent/NL7106502A/xx not_active Application Discontinuation
- 1971-05-12 CA CA112,767A patent/CA970377A/en not_active Expired
- 1971-05-12 AT AT412471A patent/AT326674B/de not_active IP Right Cessation
- 1971-05-12 SE SE613471A patent/SE387640B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| FR2100649B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1974-08-30 |
| ES391026A1 (es) | 1974-04-01 |
| NL7106502A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1971-11-16 |
| GB1361441A (en) | 1974-07-24 |
| FI52089C (fi) | 1977-06-10 |
| DK134488C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1977-05-16 |
| FI52089B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1977-02-28 |
| SU423296A3 (ru) | 1974-04-05 |
| DE2123328A1 (de) | 1971-12-02 |
| CS162753B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1975-07-15 |
| SE387640B (sv) | 1976-09-13 |
| PL76913B1 (en) | 1975-02-28 |
| ATA412471A (de) | 1975-03-15 |
| JPS5432799B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1979-10-16 |
| CA970377A (en) | 1975-07-01 |
| AT326674B (de) | 1975-12-29 |
| CS167202B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1976-04-29 |
| FR2100649A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1972-03-24 |
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