DK1341786T3 - Substituerede derivater af aminofuran-2-yl-eddikesyre og aminothien-2-yl-eddikesyre og anvendelsen deraf til behandling af migræner og smerte - Google Patents
Substituerede derivater af aminofuran-2-yl-eddikesyre og aminothien-2-yl-eddikesyre og anvendelsen deraf til behandling af migræner og smerteInfo
- Publication number
- DK1341786T3 DK1341786T3 DK01998547T DK01998547T DK1341786T3 DK 1341786 T3 DK1341786 T3 DK 1341786T3 DK 01998547 T DK01998547 T DK 01998547T DK 01998547 T DK01998547 T DK 01998547T DK 1341786 T3 DK1341786 T3 DK 1341786T3
- Authority
- DK
- Denmark
- Prior art keywords
- acetic acid
- aminothien
- aminofuran
- migraines
- pain
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Pain & Pain Management (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Furan Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10059864A DE10059864A1 (de) | 2000-11-30 | 2000-11-30 | Substituierte Amino-furan-2-yl-essigsäure- und Amino-thien-2-yl-essigsäure-Derivate |
| PCT/EP2001/013910 WO2002044171A1 (de) | 2000-11-30 | 2001-11-28 | Substituierte amino-furan-2-yl-essigsaure- und amino-thien-2-yl-essigsaure-derivate und ihre verwendung zur behandlung von migraine bzw. schmerz |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1341786T3 true DK1341786T3 (da) | 2009-04-20 |
Family
ID=7665508
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK01998547T DK1341786T3 (da) | 2000-11-30 | 2001-11-28 | Substituerede derivater af aminofuran-2-yl-eddikesyre og aminothien-2-yl-eddikesyre og anvendelsen deraf til behandling af migræner og smerte |
Country Status (30)
| Country | Link |
|---|---|
| US (1) | US6797712B2 (cs) |
| EP (1) | EP1341786B9 (cs) |
| JP (1) | JP4340063B2 (cs) |
| KR (1) | KR20030055334A (cs) |
| CN (1) | CN1326854C (cs) |
| AR (1) | AR035658A1 (cs) |
| AT (1) | ATE418552T1 (cs) |
| AU (2) | AU2002220735B2 (cs) |
| BR (1) | BR0115883A (cs) |
| CA (1) | CA2430280A1 (cs) |
| CY (1) | CY1108871T1 (cs) |
| CZ (1) | CZ20031509A3 (cs) |
| DE (2) | DE10059864A1 (cs) |
| DK (1) | DK1341786T3 (cs) |
| EC (1) | ECSDI034631S (cs) |
| ES (1) | ES2320198T3 (cs) |
| HK (1) | HK1059080A1 (cs) |
| HU (1) | HUP0303041A3 (cs) |
| IL (2) | IL156139A0 (cs) |
| MX (1) | MXPA03004303A (cs) |
| NO (1) | NO20032340L (cs) |
| NZ (1) | NZ526554A (cs) |
| PE (1) | PE20020599A1 (cs) |
| PL (1) | PL362978A1 (cs) |
| PT (1) | PT1341786E (cs) |
| RU (1) | RU2003117703A (cs) |
| SI (1) | SI1341786T1 (cs) |
| SK (1) | SK5942003A3 (cs) |
| WO (1) | WO2002044171A1 (cs) |
| ZA (1) | ZA200305009B (cs) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6794506B2 (en) * | 2000-07-21 | 2004-09-21 | Elan Pharmaceuticals, Inc. | 3-(heteroaryl) alanine derivatives-inhibitors of leukocyte adhesion mediated by VLA-4 |
| DE10125145A1 (de) | 2001-05-22 | 2002-11-28 | Gruenenthal Gmbh | Substituierte C-Furan-2-yl-methylamin- und C-Thiophen-2-yl-methylamin-Derivate |
| GB0302094D0 (en) * | 2003-01-29 | 2003-02-26 | Pharmagene Lab Ltd | EP4 receptor antagonists |
| DE10306202A1 (de) * | 2003-02-13 | 2004-08-26 | Grünenthal GmbH | Arzneimittel enthaltend substituierte 2-Aryl-Aminoessigsäure-Verbindungen und/oder substituierte 2-Heteroaryl-Aminoessigsäure-Verbindungen |
| DE10306203A1 (de) | 2003-02-13 | 2004-08-26 | Grünenthal GmbH | Arzneimittel enthaltend substituierte 2-Heteroaryl-Aminoessigsäure-Verbindungen |
| GB0324269D0 (en) * | 2003-10-16 | 2003-11-19 | Pharmagene Lab Ltd | EP4 receptor antagonists |
| US10144736B2 (en) * | 2006-07-20 | 2018-12-04 | Gilead Sciences, Inc. | Substituted pteridines useful for the treatment and prevention of viral infections |
| CU20180011A7 (es) | 2015-03-04 | 2018-06-05 | Gilead Sciences Inc | Composiciones farmacéuticas que comprenden compuestos derivados de diaminopirido (3,2-d) como moduladores de receptor de tipo toll |
| WO2018045150A1 (en) | 2016-09-02 | 2018-03-08 | Gilead Sciences, Inc. | 4,6-diamino-pyrido[3,2-d]pyrimidine derivaties as toll like receptor modulators |
| PL3507276T3 (pl) | 2016-09-02 | 2022-02-21 | Gilead Sciences, Inc. | Związki modulatory receptorów toll-podobnych |
| TWI751516B (zh) | 2019-04-17 | 2022-01-01 | 美商基利科學股份有限公司 | 類鐸受體調節劑之固體形式 |
| TWI751517B (zh) | 2019-04-17 | 2022-01-01 | 美商基利科學股份有限公司 | 類鐸受體調節劑之固體形式 |
| TW202115056A (zh) | 2019-06-28 | 2021-04-16 | 美商基利科學股份有限公司 | 類鐸受體調節劑化合物的製備方法 |
| CN115382297B (zh) * | 2022-04-12 | 2023-10-31 | 江阴市华思诚无纺布有限公司 | 熔体直纺双组分pet纺粘液体过滤材料及其制备方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU3718397A (en) * | 1996-06-28 | 1998-01-21 | University Of Southern California | Method for the synthesis of amines and amino acids with organoboron derivatives |
| DE19907385A1 (de) * | 1999-02-20 | 2000-08-24 | Boehringer Ingelheim Pharma | Neue substituierte 3-Phenoxy- und 3-Phenylalkyloxy-2-phenyl-propylamine |
| US6441237B1 (en) | 1999-02-20 | 2002-08-27 | Boehringer Ingelheim Pharma Kg | Substituted 3-phenoxy- and 3-phenylalkyloxy-2-phenyl-propylamines |
| GB0030304D0 (en) * | 2000-12-13 | 2001-01-24 | Lilly Co Eli | Compounds |
-
2000
- 2000-11-30 DE DE10059864A patent/DE10059864A1/de not_active Ceased
-
2001
- 2001-11-26 AR ARP010105486A patent/AR035658A1/es not_active Application Discontinuation
- 2001-11-28 IL IL15613901A patent/IL156139A0/xx active IP Right Grant
- 2001-11-28 SI SI200130905T patent/SI1341786T1/sl unknown
- 2001-11-28 WO PCT/EP2001/013910 patent/WO2002044171A1/de active IP Right Grant
- 2001-11-28 EP EP01998547A patent/EP1341786B9/de not_active Expired - Lifetime
- 2001-11-28 CN CNB018197876A patent/CN1326854C/zh not_active Expired - Fee Related
- 2001-11-28 AU AU2002220735A patent/AU2002220735B2/en not_active Ceased
- 2001-11-28 RU RU2003117703/04A patent/RU2003117703A/ru not_active Application Discontinuation
- 2001-11-28 AU AU2073502A patent/AU2073502A/xx active Pending
- 2001-11-28 PL PL01362978A patent/PL362978A1/xx not_active Application Discontinuation
- 2001-11-28 DK DK01998547T patent/DK1341786T3/da active
- 2001-11-28 SK SK594-2003A patent/SK5942003A3/sk not_active Application Discontinuation
- 2001-11-28 BR BR0115883-0A patent/BR0115883A/pt not_active IP Right Cessation
- 2001-11-28 HU HU0303041A patent/HUP0303041A3/hu unknown
- 2001-11-28 JP JP2002546541A patent/JP4340063B2/ja not_active Expired - Fee Related
- 2001-11-28 NZ NZ526554A patent/NZ526554A/en unknown
- 2001-11-28 PT PT01998547T patent/PT1341786E/pt unknown
- 2001-11-28 ES ES01998547T patent/ES2320198T3/es not_active Expired - Lifetime
- 2001-11-28 CZ CZ20031509A patent/CZ20031509A3/cs unknown
- 2001-11-28 DE DE50114605T patent/DE50114605D1/de not_active Expired - Lifetime
- 2001-11-28 CA CA002430280A patent/CA2430280A1/en not_active Abandoned
- 2001-11-28 KR KR10-2003-7007315A patent/KR20030055334A/ko not_active Application Discontinuation
- 2001-11-28 AT AT01998547T patent/ATE418552T1/de active
- 2001-11-28 MX MXPA03004303A patent/MXPA03004303A/es active IP Right Grant
- 2001-11-29 PE PE2001001195A patent/PE20020599A1/es not_active Application Discontinuation
-
2003
- 2003-05-23 NO NO20032340A patent/NO20032340L/no not_active Application Discontinuation
- 2003-05-27 IL IL156139A patent/IL156139A/en not_active IP Right Cessation
- 2003-05-29 EC EC2003004631F patent/ECSDI034631S/es unknown
- 2003-05-30 US US10/448,323 patent/US6797712B2/en not_active Expired - Fee Related
- 2003-06-26 ZA ZA200305009A patent/ZA200305009B/en unknown
-
2004
- 2004-03-09 HK HK04101704.1A patent/HK1059080A1/xx not_active IP Right Cessation
-
2009
- 2009-03-12 CY CY20091100279T patent/CY1108871T1/el unknown
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