DK1337547T3 - Nuklease-baseret fremgangsmåde til detektion og kvantificering af oligonukleotider - Google Patents
Nuklease-baseret fremgangsmåde til detektion og kvantificering af oligonukleotiderInfo
- Publication number
- DK1337547T3 DK1337547T3 DK01994359.6T DK01994359T DK1337547T3 DK 1337547 T3 DK1337547 T3 DK 1337547T3 DK 01994359 T DK01994359 T DK 01994359T DK 1337547 T3 DK1337547 T3 DK 1337547T3
- Authority
- DK
- Denmark
- Prior art keywords
- oigonucleotides
- nuclease
- quantification
- detection
- based procedure
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US70558700A | 2000-11-03 | 2000-11-03 | |
| PCT/US2001/049702 WO2002059137A1 (en) | 2000-11-03 | 2001-10-23 | Nuclease-based method for detecting and quantitating oligonucleotides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1337547T3 true DK1337547T3 (da) | 2014-06-10 |
Family
ID=24834124
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK01994359.6T DK1337547T3 (da) | 2000-11-03 | 2001-10-23 | Nuklease-baseret fremgangsmåde til detektion og kvantificering af oligonukleotider |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US8163477B2 (da) |
| EP (1) | EP1337547B1 (da) |
| DK (1) | DK1337547T3 (da) |
| WO (1) | WO2002059137A1 (da) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020055479A1 (en) * | 2000-01-18 | 2002-05-09 | Cowsert Lex M. | Antisense modulation of PTP1B expression |
| US7179796B2 (en) * | 2000-01-18 | 2007-02-20 | Isis Pharmaceuticals, Inc. | Antisense modulation of PTP1B expression |
| US6261840B1 (en) * | 2000-01-18 | 2001-07-17 | Isis Pharmaceuticals, Inc. | Antisense modulation of PTP1B expression |
| KR100436554B1 (ko) * | 2001-04-17 | 2004-06-18 | 삼성전자주식회사 | 혼성화된 핵산의 검출감도를 증가시키는 방법 |
| US20060089325A1 (en) * | 2004-10-13 | 2006-04-27 | Sanjay Bhanot | Antisense modulation of PTP1B expression |
| WO2008052774A2 (en) * | 2006-10-31 | 2008-05-08 | Noxxon Pharma Ag | Methods for detection of a single- or double-stranded nucleic acid molecule |
| JP2010520747A (ja) | 2007-02-23 | 2010-06-17 | パナジェン インコーポレイテッド | 支持体に固定されたｐｎａプローブと標的核酸の混成化効率又は特異度を増加させるための方法、組成物、及びキット |
| WO2009061841A2 (en) * | 2007-11-05 | 2009-05-14 | Isis Pharmaceuticals, Inc. | Modified polynucleotides as antidotes to antisense compounds |
| JP5951752B2 (ja) | 2011-04-13 | 2016-07-13 | アイオーニス ファーマシューティカルズ， インコーポレーテッドＩｏｎｉｓ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ，Ｉｎｃ． | Ｐｔｐ１ｂ発現のアンチセンス調節 |
| US10294515B2 (en) * | 2011-07-01 | 2019-05-21 | Htg Molecular Diagnostics, Inc. | Methods of detecting gene fusions |
| WO2014201306A1 (en) * | 2013-06-12 | 2014-12-18 | Oncoimmunin, Inc. | Systemic in vivo delivery of oligonucleotides |
| DK3066219T3 (da) | 2013-11-08 | 2019-03-11 | Ionis Pharmaceuticals Inc | Fremgangsmåder til påvisning af oligonukleotider |
| CN104569394A (zh) * | 2014-12-24 | 2015-04-29 | 深圳市老年医学研究所 | 一种多重miRNA肿瘤标志物检测方法及其应用 |
| EP3256601B1 (en) * | 2015-02-11 | 2021-04-07 | Biogen MA Inc. | Methods for detecting therapeutic nucleic acids |
| CN108414760A (zh) * | 2018-03-09 | 2018-08-17 | 深圳市诺亚基因科技有限公司 | 一种利用rna核酸适配体及纳米金检测血清中的茶碱的方法 |
| US20220372560A1 (en) * | 2019-10-30 | 2022-11-24 | Takeda Pharmaceutical Company Limited | Methods for detecting oligonucleotides |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69132765T2 (de) * | 1990-12-24 | 2002-02-21 | Enzo Diagnostics Inc | Verfahren zum Nachweis eines Zielpolynukleotids in einer Probe unter Verwendung eines Reagenz, das den Hintergrund verringert, und eine dieses Reagenz enthaltende Zusammensetzung und Kit. |
| ATE189831T1 (de) * | 1991-11-14 | 2000-03-15 | Dgi Inc | Nicht-radioaktives hybridisations testverfahren und satz |
| US6136531A (en) * | 1995-05-08 | 2000-10-24 | Roche Diagnostics Gmbh | Method of quantitatively detecting nucleic acids |
| US5945290A (en) * | 1998-09-18 | 1999-08-31 | Isis Pharmaceuticals, Inc. | Antisense modulation of RhoA expression |
| US6403309B1 (en) * | 1999-03-19 | 2002-06-11 | Valigen (Us), Inc. | Methods for detection of nucleic acid polymorphisms using peptide-labeled oligonucleotides and antibody arrays |
| US6573048B1 (en) * | 2000-04-18 | 2003-06-03 | Naxcor | Degradable nucleic acid probes and nucleic acid detection methods |
| US6900013B1 (en) * | 2000-08-25 | 2005-05-31 | Aviva Biosciences Corporation | Methods and compositions for identifying nucleic acid molecules using nucleolytic activities and hybridization |
-
2001
- 2001-10-23 EP EP01994359.6A patent/EP1337547B1/en not_active Expired - Lifetime
- 2001-10-23 DK DK01994359.6T patent/DK1337547T3/da active
- 2001-10-23 WO PCT/US2001/049702 patent/WO2002059137A1/en active Application Filing
-
2003
- 2003-05-27 US US10/445,996 patent/US8163477B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP1337547A4 (en) | 2004-05-06 |
| US20040005618A1 (en) | 2004-01-08 |
| EP1337547A1 (en) | 2003-08-27 |
| US8163477B2 (en) | 2012-04-24 |
| WO2002059137A1 (en) | 2002-08-01 |
| EP1337547B1 (en) | 2014-04-30 |
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