DK1334182T3 - Fremgangsmåde til fremstilling af ikke-bovint chymosin og anvendelse heraf - Google Patents

Fremgangsmåde til fremstilling af ikke-bovint chymosin og anvendelse heraf

Info

Publication number
DK1334182T3
DK1334182T3 DK01982192.5T DK01982192T DK1334182T3 DK 1334182 T3 DK1334182 T3 DK 1334182T3 DK 01982192 T DK01982192 T DK 01982192T DK 1334182 T3 DK1334182 T3 DK 1334182T3
Authority
DK
Denmark
Prior art keywords
preparation
bovine chymosin
chymosin
bovine
Prior art date
Application number
DK01982192.5T
Other languages
English (en)
Other versions
DK1334182T4 (da
Inventor
Peter Budtz
Stefan Kappeler
Zakaria Farah
Henrik Rahbek-Nielsen
Den Brink Johannes Maarten Van
Original Assignee
Eidgenoess Tech Hochschule
Chr Hansen As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24835476&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1334182(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Eidgenoess Tech Hochschule, Chr Hansen As filed Critical Eidgenoess Tech Hochschule
Publication of DK1334182T3 publication Critical patent/DK1334182T3/da
Application granted granted Critical
Publication of DK1334182T4 publication Critical patent/DK1334182T4/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
    • A23C19/00—Cheese; Cheese preparations; Making thereof
    • A23C19/02—Making cheese curd
    • A23C19/04—Making cheese curd characterised by the use of specific enzymes of vegetable or animal origin
    • A23C19/043—Enzymes other than proteolytic enzymes or milk clotting enzymes, e.g. lipase, lysosyme
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6478—Aspartic endopeptidases (3.4.23)
    • C12N9/6483—Chymosin (3.4.23.4), i.e. rennin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/23—Aspartic endopeptidases (3.4.23)
    • C12Y304/23004—Chymosin (3.4.23.4), i.e. rennin
DK01982192.5T 2000-11-06 2001-11-06 Fremgangsmåde til fremstilling af ikke-bovint chymosin og anvendelse heraf DK1334182T4 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US70591700A 2000-11-06 2000-11-06
PCT/DK2001/000731 WO2002036752A2 (en) 2000-11-06 2001-11-06 Method of producing non-bovine chymosin and use thereof

Publications (2)

Publication Number Publication Date
DK1334182T3 true DK1334182T3 (da) 2011-01-17
DK1334182T4 DK1334182T4 (da) 2021-04-26

Family

ID=24835476

Family Applications (2)

Application Number Title Priority Date Filing Date
DK01982192.5T DK1334182T4 (da) 2000-11-06 2001-11-06 Fremgangsmåde til fremstilling af ikke-bovint chymosin og anvendelse heraf
DK10185159.0T DK2365069T3 (da) 2000-11-06 2001-11-06 Fremgangsmåde til fremstilling af ikke-bovint chymosin og anvendelse heraf

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK10185159.0T DK2365069T3 (da) 2000-11-06 2001-11-06 Fremgangsmåde til fremstilling af ikke-bovint chymosin og anvendelse heraf

Country Status (10)

Country Link
US (5) US20020164696A1 (da)
EP (2) EP1334182B2 (da)
AR (1) AR031620A1 (da)
AT (1) ATE486933T1 (da)
AU (1) AU2002213838A1 (da)
DE (1) DE60143406D1 (da)
DK (2) DK1334182T4 (da)
ES (2) ES2669299T3 (da)
TR (1) TR201806782T4 (da)
WO (1) WO2002036752A2 (da)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE0004808D0 (sv) * 2000-12-20 2000-12-20 Apbiotech Ab Method for the purification of an enzyme
US20020160445A1 (en) * 2001-02-09 2002-10-31 Marianne Harboe Method of providing polypeptide preparations with reduced enzymatic side activities
WO2005089040A2 (en) * 2004-03-23 2005-09-29 Chr. Hansen A/S Method of producing chymosin c and uses thereof
WO2005093072A1 (en) 2004-03-25 2005-10-06 Iogen Bio-Products Corporation Modified xylanases exhibiting improved expression
ES2246175B1 (es) * 2004-07-30 2007-03-16 Felix Claverie Martin "procedimiento para producir quimosina caprina recombinante para la coagulacion de la leche de cabra en la fabricacion de queso".
US20080131487A1 (en) * 2006-11-30 2008-06-05 Dag Ommundsen Chymosin for the prevention and treatment of gastrointestinal disorders
WO2008098973A1 (en) * 2007-02-13 2008-08-21 Chr. Hansen A/S Coagulation of milk
ES2336171B1 (es) * 2007-07-27 2011-05-11 Universidad De Santiago De Compostela Uso de la quimosina recombinante activa.
US7963783B2 (en) * 2008-02-25 2011-06-21 Cooper Technologies Company Separable connector system with vents in bushing nose
WO2013093049A2 (en) 2011-12-23 2013-06-27 Chr. Hansen A/S Method for making cheese
DK2844750T3 (da) 2012-05-03 2018-10-01 Dsm Ip Assets Bv Forbedrede enzymvarianter
JP2015518718A (ja) 2012-05-25 2015-07-06 セーホーエル．ハンセン アクティーゼルスカブ 凝乳特性が改善されたキモシン変異体
US20160002618A1 (en) * 2013-02-05 2016-01-07 Chr. Hansen A/S Improved purification of proteins via a deglycosylation step
WO2015007638A1 (en) * 2013-07-18 2015-01-22 Chr. Hansen A/S Milk clotting aspartic protease enzyme composition
US9689016B2 (en) * 2013-12-18 2017-06-27 Caliber Biotherapeutics, Llc Method for in vivo production of deglycosylated recombinant proteins used as substrate for downstream protein glycoremodeling
RU2739004C1 (ru) * 2014-02-26 2020-12-21 Кхр. Хансен А/С Варианты химозина с улучшенными молокосвертывающими свойствами
MX2017010058A (es) * 2015-02-10 2017-11-13 Chr Hansen As Mezclas de quimosinas con propiedades de coagulacion de la leche mejoradas.
US11174473B2 (en) 2015-06-22 2021-11-16 Chr. Hansen A/S Variants of chymosin with improved properties
BR112018003493A2 (pt) * 2015-08-31 2018-09-18 Chr Hansen As variantes de quimosina com propriedades aperfeiçoadas
EP3143879A1 (en) * 2015-09-18 2017-03-22 DSM IP Assets B.V. Yogurt with reduced ripening
US11041163B2 (en) 2015-11-13 2021-06-22 Tarlan Mammedov Production of in vivo N-deglycosylated recombinant proteins by co-expression with endo H
AU2017266397B2 (en) 2016-05-19 2021-03-11 Chr. Hansen A/S Variants of Chymosin with improved milk-clotting properties
CA3024210C (en) 2016-05-19 2024-03-19 Chr. Hansen A/S Variants of chymosin with improved milk-clotting properties
MX2020007300A (es) 2018-01-15 2020-09-25 Chr Hansen As Producto de leche fermentada y preparacion del mismo usando fosfolipasa.
US11229219B1 (en) * 2020-09-18 2022-01-25 United Arab Emirates University Camel-milk products with plant-based protein additive
US10894812B1 (en) 2020-09-30 2021-01-19 Alpine Roads, Inc. Recombinant milk proteins
EP4222167A1 (en) 2020-09-30 2023-08-09 Nobell Foods, Inc. Recombinant milk proteins and food compositions comprising the same
US10947552B1 (en) 2020-09-30 2021-03-16 Alpine Roads, Inc. Recombinant fusion proteins for producing milk proteins in plants
WO2023001832A1 (en) 2021-07-20 2023-01-26 Chr. Hansen A/S Composition for clotting milk, methods and uses thereof

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59166086A (ja) 1983-03-09 1984-09-19 Teruhiko Beppu 新規な発現型プラスミドとそれらを用いて仔牛プロキモシン遺伝子を大腸菌内で発現させる方法
US5364770A (en) 1985-08-29 1994-11-15 Genencor International Inc. Heterologous polypeptides expressed in aspergillus
CA2152898C (en) * 1992-12-30 2003-04-29 Hans Israelsen Recombinant lactic acid bacterium containing an inserted promoter and method of constructing same
DE69401490T2 (de) 1993-11-10 1997-04-30 Pfizer Prozess zur Rückfaltung von (pro-)Chymosin, unter Rückführung von Harnstoff
WO1995029999A2 (en) 1994-05-03 1995-11-09 Chr. Hansen A/S A process for separating milk clotting enzymes, and stable rennet compositions
WO1996019582A1 (en) * 1994-12-21 1996-06-27 Chr. Hansen A/S Microbially derived rennin having enhanced milk clotting activity and method of producing same
CA2221271A1 (en) * 1995-05-18 1996-11-21 Genencor International, Inc. Expression of glycosyltransferase in aspergillus
US5554398A (en) * 1995-07-10 1996-09-10 Wisconsin Alumni Research Foundation Process for manufacturing reduced-fat Cheddar cheese
ES2277910T3 (es) † 2000-02-08 2007-08-01 Upfront Chromatography A/S Nuevos materiales de resina y su uso para recuperar proteinas o peptidos.

Also Published As

Publication number Publication date
US20110287137A1 (en) 2011-11-24
US9307775B2 (en) 2016-04-12
ES2354775T5 (es) 2021-12-23
TR201806782T4 (tr) 2018-06-21
US20140072670A1 (en) 2014-03-13
US7270989B2 (en) 2007-09-18
DK2365069T3 (da) 2018-04-23
EP1334182A2 (en) 2003-08-13
EP2365069B1 (en) 2018-02-21
EP2365069A1 (en) 2011-09-14
ES2669299T3 (es) 2018-05-24
AU2002213838A1 (en) 2002-05-15
WO2002036752A2 (en) 2002-05-10
US20040180410A1 (en) 2004-09-16
DE60143406D1 (de) 2010-12-16
EP1334182B2 (en) 2021-03-24
EP1334182B1 (en) 2010-11-03
US8545909B2 (en) 2013-10-01
US20080226768A1 (en) 2008-09-18
US20020164696A1 (en) 2002-11-07
WO2002036752A3 (en) 2002-09-26
ES2354775T3 (es) 2011-03-17
AR031620A1 (es) 2003-09-24
ATE486933T1 (de) 2010-11-15
DK1334182T4 (da) 2021-04-26

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