DK1325011T3 - Fremgangsmåder og forbindelser til behandling af proliferative sygdomme - Google Patents
Fremgangsmåder og forbindelser til behandling af proliferative sygdommeInfo
- Publication number
- DK1325011T3 DK1325011T3 DK01972948T DK01972948T DK1325011T3 DK 1325011 T3 DK1325011 T3 DK 1325011T3 DK 01972948 T DK01972948 T DK 01972948T DK 01972948 T DK01972948 T DK 01972948T DK 1325011 T3 DK1325011 T3 DK 1325011T3
- Authority
- DK
- Denmark
- Prior art keywords
- treatment
- compounds
- methods
- proliferative diseases
- formula
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
- C07D487/14—Ortho-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US23661600P | 2000-09-29 | 2000-09-29 | |
PCT/US2001/027728 WO2002028861A2 (en) | 2000-09-29 | 2001-09-24 | Methods and compounds for treating proliferative diseases |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1325011T3 true DK1325011T3 (da) | 2004-08-16 |
Family
ID=22890242
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK01972948T DK1325011T3 (da) | 2000-09-29 | 2001-09-24 | Fremgangsmåder og forbindelser til behandling af proliferative sygdomme |
Country Status (10)
Country | Link |
---|---|
US (1) | US7109229B2 (de) |
EP (1) | EP1325011B1 (de) |
AT (1) | ATE266031T1 (de) |
AU (1) | AU2001292579A1 (de) |
DE (1) | DE60103171T2 (de) |
DK (1) | DK1325011T3 (de) |
ES (1) | ES2220811T3 (de) |
PT (1) | PT1325011E (de) |
TR (1) | TR200401316T4 (de) |
WO (1) | WO2002028861A2 (de) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20050171182A1 (en) * | 2003-12-11 | 2005-08-04 | Roger Briesewitz | Methods and compositions for use in the treatment of mutant receptor tyrosine kinase driven cellular proliferative diseases |
US7169802B2 (en) | 2003-12-23 | 2007-01-30 | Cephalon, Inc. | Fused pyrrolocarbazoles |
US7241779B2 (en) * | 2003-12-23 | 2007-07-10 | Cephalon, Inc. | Fused pyrrolocarbazoles |
EP2102207B1 (de) | 2006-12-07 | 2010-06-02 | F.Hoffmann-La Roche Ag | Spiropiperidinderivate als antagonisten des via-rezeptors |
WO2008077810A2 (en) | 2006-12-22 | 2008-07-03 | F. Hoffmann-La Roche Ag | Spiro-piperidine derivatives |
AU2009298367A1 (en) * | 2008-10-01 | 2010-04-08 | The University Of North Carolina At Chapel Hill | Hematopoietic protection against chemotherapeutic compounds using selective cyclin-dependent kinase 4/6 inhibitors |
US20110224221A1 (en) * | 2008-10-01 | 2011-09-15 | Sharpless Norman E | Hematopoietic protection against ionizing radiation using selective cyclin-dependent kinase 4/6 inhibitors |
CN103965204B (zh) * | 2008-11-19 | 2016-09-07 | 赛福伦公司 | 吲唑并[5,4-a]吡咯并[3,4-c]咔唑化合物的新形式 |
JP2012526850A (ja) | 2009-05-13 | 2012-11-01 | ザ ユニバーシティ オブ ノース カロライナ アット チャペル ヒル | サイクリン依存性キナーゼ阻害剤及びその用法 |
NZ604135A (en) * | 2010-05-18 | 2015-02-27 | Cephalon Inc | Method for purifying a fused pyrrolocarbazole derivative |
EP3399026A1 (de) | 2010-06-14 | 2018-11-07 | The Scripps Research Institute | Neuprogrammierung von zellen für ein neues zellschicksal |
JP2013545758A (ja) | 2010-11-17 | 2013-12-26 | ザ ユニバーシティ オブ ノース カロライナ アット チャペル ヒル | 増殖性キナーゼcdk4及びcdk6の阻害による虚血からの腎組織の保護 |
US9487530B2 (en) | 2013-03-15 | 2016-11-08 | G1 Therapeutics, Inc. | Transient protection of normal cells during chemotherapy |
CA2906157C (en) | 2013-03-15 | 2022-05-17 | G1 Therapeutics, Inc. | Highly active anti-neoplastic and anti-proliferative agents |
US20150297607A1 (en) | 2014-04-17 | 2015-10-22 | G1 Therapeutics, Inc. | Tricyclic Lactams for Use in the Protection of Normal Cells During Chemotherapy |
WO2016040848A1 (en) | 2014-09-12 | 2016-03-17 | G1 Therapeutics, Inc. | Treatment of rb-negative tumors using topoisomerase inhibitors in combination with cyclin dependent kinase 4/6 inhibitors |
WO2016040858A1 (en) | 2014-09-12 | 2016-03-17 | G1 Therapeutics, Inc. | Combinations and dosing regimes to treat rb-positive tumors |
US11077110B2 (en) | 2016-03-18 | 2021-08-03 | Tufts Medical Center | Compositions and methods for treating and preventing metabolic disorders |
EP3606518A4 (de) | 2017-04-01 | 2021-04-07 | The Broad Institute, Inc. | Verfahren und zusammensetzungen zur detektion und zur modulation einer immuntherapieresistenzgensignatur in krebs |
US20220154282A1 (en) | 2019-03-12 | 2022-05-19 | The Broad Institute, Inc. | Detection means, compositions and methods for modulating synovial sarcoma cells |
US10988479B1 (en) | 2020-06-15 | 2021-04-27 | G1 Therapeutics, Inc. | Morphic forms of trilaciclib and methods of manufacture thereof |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE4217964A1 (de) * | 1992-05-30 | 1993-12-02 | Goedecke Ag | Indolocarbazol-Imide und deren Verwendung |
US5679694A (en) * | 1992-07-20 | 1997-10-21 | The Wellcome Foundation Ltd. | Tetracyclic compounds, intermediates for their preparation and their use as antitumor agents |
-
2001
- 2001-09-24 US US10/344,245 patent/US7109229B2/en not_active Expired - Fee Related
- 2001-09-24 ES ES01972948T patent/ES2220811T3/es not_active Expired - Lifetime
- 2001-09-24 TR TR2004/01316T patent/TR200401316T4/xx unknown
- 2001-09-24 EP EP01972948A patent/EP1325011B1/de not_active Expired - Lifetime
- 2001-09-24 DK DK01972948T patent/DK1325011T3/da active
- 2001-09-24 WO PCT/US2001/027728 patent/WO2002028861A2/en active IP Right Grant
- 2001-09-24 PT PT01972948T patent/PT1325011E/pt unknown
- 2001-09-24 AT AT01972948T patent/ATE266031T1/de not_active IP Right Cessation
- 2001-09-24 DE DE60103171T patent/DE60103171T2/de not_active Expired - Fee Related
- 2001-09-24 AU AU2001292579A patent/AU2001292579A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
US7109229B2 (en) | 2006-09-19 |
WO2002028861A2 (en) | 2002-04-11 |
DE60103171D1 (de) | 2004-06-09 |
AU2001292579A1 (en) | 2002-04-15 |
TR200401316T4 (tr) | 2004-07-21 |
ATE266031T1 (de) | 2004-05-15 |
WO2002028861A8 (en) | 2003-11-20 |
ES2220811T3 (es) | 2004-12-16 |
PT1325011E (pt) | 2004-09-30 |
US20040048915A1 (en) | 2004-03-11 |
EP1325011B1 (de) | 2004-05-06 |
DE60103171T2 (de) | 2004-11-11 |
EP1325011A2 (de) | 2003-07-09 |
WO2002028861A3 (en) | 2002-08-01 |
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