DK130922B - Analogifremgangsmåde til fremstilling af alfa-(3-indolyl)-alkansyreforbindelser. - Google Patents
Analogifremgangsmåde til fremstilling af alfa-(3-indolyl)-alkansyreforbindelser.Info
- Publication number
- DK130922B DK130922B DK290564AA DK290564A DK130922B DK 130922 B DK130922 B DK 130922B DK 290564A A DK290564A A DK 290564AA DK 290564 A DK290564 A DK 290564A DK 130922 B DK130922 B DK 130922B
- Authority
- DK
- Denmark
- Prior art keywords
- indolyl
- alpha
- preparation
- acid compounds
- alkanoic acid
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D209/26—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an acyl radical attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D209/26—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an acyl radical attached to the ring nitrogen atom
- C07D209/28—1-(4-Chlorobenzoyl)-2-methyl-indolyl-3-acetic acid, substituted in position 5 by an oxygen or nitrogen atom; Esters thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (12)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US16461562A | 1962-01-05 | 1962-01-05 | |
US28693563 US3161654A (en) | 1962-01-05 | 1963-06-11 | alpha-(1-aroyl-3-indolyl) alkanoic acids |
US296451A US3201414A (en) | 1963-07-22 | 1963-07-22 | New 1-heteroacyl-3-indolyl aliphatic acids |
US31045463A | 1963-09-20 | 1963-09-20 | |
US31047763A | 1963-09-20 | 1963-09-20 | |
US314503A US3242185A (en) | 1963-10-07 | 1963-10-07 | Lower aliphatic acids, salts and derivatives thereof |
US32386363A | 1963-11-04 | 1963-11-04 | |
US321328A US3275644A (en) | 1962-01-05 | 1963-11-04 | Certain 1-azolylindol-3-ylaliphatic acids |
US321686A US3275645A (en) | 1962-01-05 | 1963-11-06 | N-(1-acyl-3-indolyl)-acids |
US437338A US3338921A (en) | 1962-01-05 | 1965-01-26 | Thenoic and furoic acids |
US442152A US3328423A (en) | 1962-01-05 | 1965-03-23 | alpha-(3-indolyl)-cyclopropyl lower aliphatic acids |
US528020A US3316267A (en) | 1962-01-05 | 1966-02-15 | Indolyl acids |
Publications (2)
Publication Number | Publication Date |
---|---|
DK130922B true DK130922B (da) | 1975-05-05 |
DK130922C DK130922C (fr) | 1975-10-13 |
Family
ID=27583773
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK290564AA DK130922B (da) | 1962-01-05 | 1964-06-10 | Analogifremgangsmåde til fremstilling af alfa-(3-indolyl)-alkansyreforbindelser. |
DK290664AA DK117068B (da) | 1962-01-05 | 1964-06-10 | Fremgangsmåde til fremstilling af N-1-aroylindolyleddikesyreforbindelser. |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK290664AA DK117068B (da) | 1962-01-05 | 1964-06-10 | Fremgangsmåde til fremstilling af N-1-aroylindolyleddikesyreforbindelser. |
Country Status (14)
Country | Link |
---|---|
US (6) | US3161654A (fr) |
AT (1) | AT290523B (fr) |
BE (3) | BE649169A (fr) |
BR (4) | BR6459899D0 (fr) |
CH (3) | CH447169A (fr) |
CS (1) | CS164201B2 (fr) |
DE (1) | DE1470069A1 (fr) |
DK (2) | DK130922B (fr) |
FI (1) | FI44910C (fr) |
FR (6) | FR1426907A (fr) |
GB (3) | GB1063230A (fr) |
IL (3) | IL21376A (fr) |
NL (3) | NL6406405A (fr) |
SE (1) | SE300985B (fr) |
Families Citing this family (117)
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US3259622A (en) * | 1962-09-07 | 1966-07-05 | Merck & Co Inc | 1-benzyl-3-indolyl-alpha-haloalkyl and alkylidenyl acetic acids |
US3376316A (en) * | 1962-12-28 | 1968-04-02 | Merck & Co Inc | Lower alkyl gamma keto acid 2-pyranyl esters |
US3306822A (en) * | 1963-05-20 | 1967-02-28 | Merck & Co Inc | Anti-inflammatory therapy with 3-indolinyl compounds |
BE659364A (fr) * | 1964-02-05 | |||
US3450814A (en) * | 1964-07-15 | 1969-06-17 | Chemway Corp | Ophthalmic compositions containing alginic acid salts of pilocarpine,atropine and physostigmine |
US3271394A (en) * | 1964-12-31 | 1966-09-06 | Merck & Co Inc | Alpha-indolyl-3-acetic acid esters |
US3417096A (en) * | 1965-07-01 | 1968-12-17 | Bristol Myers Co | Certain 5(1-benzoyl-3-indolylmethyl) tetrazoles |
US3397211A (en) * | 1966-09-09 | 1968-08-13 | Merck & Co Inc | Process for preparing 3-indolyl acetic acids |
US3471514A (en) * | 1966-11-14 | 1969-10-07 | Merck & Co Inc | Process for alpha-(5-nitroindolyl-3)-alkanoic acids |
US3468907A (en) * | 1967-04-10 | 1969-09-23 | Schering Corp | Glyceryl esters of alpha-(1-aroyl-3-indolyl)alkanoic acids |
NL6804994A (fr) * | 1967-04-11 | 1968-10-14 | ||
US3476770A (en) * | 1967-04-14 | 1969-11-04 | Parke Davis & Co | 2-methyl-7-phenylindole-3-acetic acid compounds |
US3497526A (en) * | 1967-07-26 | 1970-02-24 | Merck & Co Inc | Organo-metallic compounds |
US3501498A (en) * | 1967-07-26 | 1970-03-17 | Merck & Co Inc | Nitro- and amino-substituted 1-p-chlorobenzyl-2-methyl-3-indolylacetic acids |
HU162374B (fr) * | 1969-04-03 | 1973-02-28 | ||
US3800041A (en) * | 1971-03-02 | 1974-03-26 | Lilly Co Eli | Analgesic compositions and methods |
US3939178A (en) * | 1971-06-01 | 1976-02-17 | American Home Products Corporation | Certain pyrano [3,4-b]indoles and thiopyrano[3,4-b]indoles |
JPS49149723U (fr) * | 1973-04-25 | 1974-12-25 | ||
US4029798A (en) * | 1975-06-02 | 1977-06-14 | Sumitomo Chemical Company, Limited | Analgetic composition |
US4119638A (en) * | 1976-11-29 | 1978-10-10 | G. D. Searle & Co. | Thio-ester of 1 (p-chlorobenzoyl)-5-methoxy-2-methylindole-3-acetic acid |
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DE2935776A1 (de) * | 1979-09-05 | 1981-04-16 | Theodor Prof. Dr. 4400 Münster Eckert | Organische salze des indometacin, des naproxen und des diclofenac, ihre herstellung und sie enthaltende arzneimittel |
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CH307633A (de) * | 1952-07-23 | 1955-06-15 | Ciba Geigy | Verfahren zur Herstellung eines Anthrachinonküpenfarbstoffes. |
-
1962
- 1962-03-16 AT AT403766A patent/AT290523B/de not_active IP Right Cessation
-
1963
- 1963-06-11 US US28693563 patent/US3161654A/en not_active Expired - Lifetime
- 1963-11-04 US US321328A patent/US3275644A/en not_active Expired - Lifetime
- 1963-11-06 US US321686A patent/US3275645A/en not_active Expired - Lifetime
-
1964
- 1964-05-21 IL IL21376A patent/IL21376A/xx unknown
- 1964-05-31 IL IL21431A patent/IL21431A/xx unknown
- 1964-06-03 IL IL21454A patent/IL21454A/xx unknown
- 1964-06-05 NL NL6406405A patent/NL6406405A/xx unknown
- 1964-06-05 NL NL6406406A patent/NL6406406A/xx unknown
- 1964-06-08 GB GB23653/64A patent/GB1063230A/en not_active Expired
- 1964-06-08 GB GB23654/64A patent/GB1063247A/en not_active Expired
- 1964-06-08 GB GB23652/64A patent/GB1069775A/en not_active Expired
- 1964-06-09 DE DE19641470069 patent/DE1470069A1/de active Pending
- 1964-06-10 SE SE7077/64A patent/SE300985B/xx unknown
- 1964-06-10 FR FR977785A patent/FR1426907A/fr not_active Expired
- 1964-06-10 CH CH755064A patent/CH447169A/de unknown
- 1964-06-10 FR FR977784A patent/FR1459744A/fr not_active Expired
- 1964-06-10 CH CH755164A patent/CH446333A/de unknown
- 1964-06-10 DK DK290564AA patent/DK130922B/da unknown
- 1964-06-10 CS CS3348A patent/CS164201B2/cs unknown
- 1964-06-10 BR BR159899/64A patent/BR6459899D0/pt unknown
- 1964-06-10 BR BR159897/64A patent/BR6459897D0/pt unknown
- 1964-06-10 FR FR977783A patent/FR1452607A/fr not_active Expired
- 1964-06-10 DK DK290664AA patent/DK117068B/da unknown
- 1964-06-10 BR BR159900/64A patent/BR6459900D0/pt unknown
- 1964-06-10 CH CH754964A patent/CH455775A/de unknown
- 1964-06-10 FI FI641258A patent/FI44910C/fi active
- 1964-06-11 BE BE649169D patent/BE649169A/xx unknown
- 1964-06-11 NL NL6406640A patent/NL6406640A/xx unknown
- 1964-06-11 BE BE649166D patent/BE649166A/xx unknown
- 1964-06-11 BE BE649167D patent/BE649167A/xx unknown
- 1964-09-09 FR FR987606A patent/FR4065M/fr not_active Expired
- 1964-09-09 FR FR987607A patent/FR3933M/fr not_active Expired
- 1964-09-09 FR FR987605A patent/FR4114M/fr not_active Expired
-
1965
- 1965-01-26 US US437338A patent/US3338921A/en not_active Expired - Lifetime
- 1965-03-23 US US442152A patent/US3328423A/en not_active Expired - Lifetime
-
1966
- 1966-02-15 US US528020A patent/US3316267A/en not_active Expired - Lifetime
-
1969
- 1969-12-03 BR BR214739/69A patent/BR6914739D0/pt unknown
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