DK120898B - Fremgangsmåde til fremstilling af indolyleddikesyreforbindelser. - Google Patents
Fremgangsmåde til fremstilling af indolyleddikesyreforbindelser.Info
- Publication number
- DK120898B DK120898B DK423863AA DK423863A DK120898B DK 120898 B DK120898 B DK 120898B DK 423863A A DK423863A A DK 423863AA DK 423863 A DK423863 A DK 423863A DK 120898 B DK120898 B DK 120898B
- Authority
- DK
- Denmark
- Prior art keywords
- preparation
- acid compounds
- indoleacetic acid
- indoleacetic
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/12—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D209/22—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an aralkyl radical attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D209/26—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an acyl radical attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Indole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US222179A US3259622A (en) | 1962-09-07 | 1962-09-07 | 1-benzyl-3-indolyl-alpha-haloalkyl and alkylidenyl acetic acids |
| US45201865A | 1965-04-29 | 1965-04-29 | |
| US452015A US3399198A (en) | 1962-09-07 | 1965-04-29 | 1-pyrimidinoyl-and 1-imidazoloyl-3-haloacetyl indoles |
| US452010A US3388127A (en) | 1962-09-07 | 1965-04-29 | Alpha-halomethyl-1-pyrazine carbonyl-3-indolylacetic acids |
| US452022A US3326930A (en) | 1962-09-07 | 1965-04-29 | alpha-halomethyl-(1-oxazole-carbonylindol-3-yl) acetic acids and certain intermediates therefor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK120898B true DK120898B (da) | 1971-08-02 |
Family
ID=27539838
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK423863AA DK120898B (da) | 1962-09-07 | 1963-09-07 | Fremgangsmåde til fremstilling af indolyleddikesyreforbindelser. |
Country Status (10)
| Country | Link |
|---|---|
| US (5) | US3259622A (da) |
| AT (2) | AT263765B (da) |
| BE (2) | BE637036A (da) |
| CH (1) | CH450416A (da) |
| DE (1) | DE1470045A1 (da) |
| DK (1) | DK120898B (da) |
| FR (3) | FR1535407A (da) |
| GB (6) | GB1063383A (da) |
| NL (2) | NL297645A (da) |
| SE (1) | SE309040B (da) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3929820A (en) * | 1967-09-26 | 1975-12-30 | Bayer Ag | Process for the production of N-tritylimidazoles |
| JPS5683472A (en) * | 1979-12-12 | 1981-07-08 | Teijin Ltd | Preparation of 3-acyl-1-substituted indole derivative |
| US4499279A (en) * | 1980-04-10 | 1985-02-12 | Sandoz, Inc. | Isoxazolyl indolamines |
| JPS57159738A (en) * | 1981-03-30 | 1982-10-01 | Sagami Chem Res Center | 2-halomethylene-arylacetice acid derivative |
| EP0411150B1 (en) * | 1989-02-10 | 1996-11-27 | Otsuka Pharmaceutical Co., Ltd. | Indole derivatives, preparation thereof, and drug for preventing and treating nephritis containing same |
| US5238938A (en) * | 1989-02-10 | 1993-08-24 | Otsuka Pharmaceutical Co., Ltd. | Indole derivatives |
| US5166170A (en) * | 1989-07-03 | 1992-11-24 | Hoechst-Roussel Pharmaceuticals Incorporated | 2-(aminoaryl) indoles and indolines as topical antiinflammatory agents for the treatment of skin disorders |
| GB9004301D0 (en) * | 1990-02-26 | 1990-04-18 | Fujisawa Pharmaceutical Co | Indolebutyric acid derivatives and process for preparation thereof |
| US5283251A (en) * | 1990-02-26 | 1994-02-01 | Fujisawa Pharmaceutical Co., Ltd. | Indole derivatives |
| FR2658818B1 (fr) * | 1990-02-27 | 1993-12-31 | Adir Cie | Nouveaux derives a structure naphtalenique, leur procede de preparation et les compositions pharmaceutiques qui les contiennent. |
| US5064851A (en) * | 1990-07-24 | 1991-11-12 | Pfizer Inc. | 3-(1-substituted-pyrazoyl)-2-oxindole derivatives, compositions and use |
| JP2599665B2 (ja) * | 1991-05-01 | 1997-04-09 | 大塚製薬株式会社 | ピラジン誘導体 |
| IL109311A0 (en) * | 1993-04-16 | 1994-07-31 | Lilly Co Eli | 1H-indole-3-acetamide sPla2 inhibitors |
| CN1067054C (zh) * | 1994-04-01 | 2001-06-13 | 伊莱利利公司 | 1H-吲哚-3-乙醛酰胺sPLA2抑制剂 |
| US5641800A (en) * | 1994-07-21 | 1997-06-24 | Eli Lilly And Company | 1H-indole-1-functional sPLA2 inhibitors |
| US6214876B1 (en) | 1994-07-21 | 2001-04-10 | Eli Lilly And Company | Indene-1-acetamide sPLA2 inhibitors |
| US5604253A (en) * | 1995-05-22 | 1997-02-18 | Merck Frosst Canada, Inc. | N-benzylindol-3-yl propanoic acid derivatives as cyclooxygenase inhibitors |
| TR200003130T2 (tr) | 1998-04-28 | 2001-01-22 | Arzneimittelwerk Dresden Gmbh | Yeni hidroksiindoller, bunların fosfodiesteraz 4 inhibitörleri olarak kullanımları ve hazırlanmaları için işlemler |
| EP0980863B1 (en) * | 1998-08-17 | 2005-02-02 | Givaudan SA | Oxime carboxylic acid derivatives |
| ES2235412T3 (es) | 1998-08-17 | 2005-07-01 | Givaudan Sa | Derivados de oxima de acido carboxilico. |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB869775A (en) * | 1958-09-24 | 1961-06-07 | Upjohn Co | 3-indolyl ketones |
| US2978459A (en) * | 1959-08-05 | 1961-04-04 | Upjohn Co | Ketals of (3-indolyl)-aminoalkanones |
| US3201414A (en) * | 1963-07-22 | 1965-08-17 | Merck & Co Inc | New 1-heteroacyl-3-indolyl aliphatic acids |
| AT290523B (de) * | 1962-01-05 | 1971-06-11 | Merck & Co Inc | Verfahren zur Herstellung neuer α-(3-Indolyl)-carbonsäuren |
| US3242192A (en) * | 1962-09-07 | 1966-03-22 | Merck & Co Inc | Alpha-haloalkyl (3-indolyl) acetic acid derivatives |
-
1962
- 1962-09-07 US US222179A patent/US3259622A/en not_active Expired - Lifetime
-
1963
- 1963-08-26 GB GB33704/63A patent/GB1063383A/en not_active Expired
- 1963-08-26 DE DE19631470045 patent/DE1470045A1/de active Pending
- 1963-08-26 GB GB5704/66A patent/GB1049840A/en not_active Expired
- 1963-08-26 GB GB43065/65A patent/GB1063384A/en not_active Expired
- 1963-08-26 GB GB43066/65A patent/GB1063385A/en not_active Expired
- 1963-08-26 GB GB5705/66A patent/GB1048347A/en not_active Expired
- 1963-08-26 GB GB33705/63A patent/GB1048346A/en not_active Expired
- 1963-08-28 AT AT481266A patent/AT263765B/de active
- 1963-08-28 AT AT693363A patent/AT262274B/de active
- 1963-08-30 CH CH1075363A patent/CH450416A/de unknown
- 1963-09-05 BE BE637036D patent/BE637036A/xx unknown
- 1963-09-05 BE BE637037D patent/BE637037A/xx unknown
- 1963-09-06 FR FR946855A patent/FR1535407A/fr not_active Expired
- 1963-09-07 DK DK423863AA patent/DK120898B/da unknown
- 1963-09-09 NL NL297645D patent/NL297645A/xx unknown
- 1963-09-09 NL NL297644D patent/NL297644A/xx unknown
- 1963-12-05 FR FR956207A patent/FR3556M/fr not_active Expired
- 1963-12-05 FR FR956206A patent/FR3555M/fr not_active Expired
-
1965
- 1965-04-29 US US452018A patent/US3426038A/en not_active Expired - Lifetime
- 1965-04-29 US US452022A patent/US3326930A/en not_active Expired - Lifetime
- 1965-04-29 US US452010A patent/US3388127A/en not_active Expired - Lifetime
- 1965-04-29 US US452015A patent/US3399198A/en not_active Expired - Lifetime
- 1965-07-15 SE SE9365/65A patent/SE309040B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US3388127A (en) | 1968-06-11 |
| US3426038A (en) | 1969-02-04 |
| NL297644A (da) | 1965-11-10 |
| GB1063384A (en) | 1967-03-30 |
| AT263765B (de) | 1968-08-12 |
| CH450416A (de) | 1968-01-31 |
| BE637036A (da) | 1964-03-05 |
| FR1535407A (fr) | 1968-08-09 |
| US3326930A (en) | 1967-06-20 |
| GB1049840A (en) | 1966-11-30 |
| GB1063385A (en) | 1967-03-30 |
| FR3556M (da) | 1965-10-22 |
| SE309040B (da) | 1969-03-10 |
| AT262274B (de) | 1968-06-10 |
| BE637037A (da) | 1964-03-05 |
| US3399198A (en) | 1968-08-27 |
| NL297645A (da) | 1965-11-10 |
| GB1063383A (en) | 1967-03-30 |
| FR3555M (da) | 1965-10-22 |
| US3259622A (en) | 1966-07-05 |
| GB1048347A (en) | 1966-11-16 |
| DE1470045A1 (de) | 1969-05-29 |
| GB1048346A (en) | 1966-11-16 |
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