DK244179A - Fremgangsmaade til fremstilling af krystallinsk natrium og kaliumindomethacin og trihydrater deraf - Google Patents
Fremgangsmaade til fremstilling af krystallinsk natrium og kaliumindomethacin og trihydrater derafInfo
- Publication number
- DK244179A DK244179A DK244179A DK244179A DK244179A DK 244179 A DK244179 A DK 244179A DK 244179 A DK244179 A DK 244179A DK 244179 A DK244179 A DK 244179A DK 244179 A DK244179 A DK 244179A
- Authority
- DK
- Denmark
- Prior art keywords
- potassium
- crystallinic
- trihydrates
- sodium
- procedure
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D209/26—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an acyl radical attached to the ring nitrogen atom
- C07D209/28—1-(4-Chlorobenzoyl)-2-methyl-indolyl-3-acetic acid, substituted in position 5 by an oxygen or nitrogen atom; Esters thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Indole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US91510578A | 1978-06-13 | 1978-06-13 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK244179A true DK244179A (da) | 1979-12-14 |
Family
ID=25435227
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK244179A DK244179A (da) | 1978-06-13 | 1979-06-12 | Fremgangsmaade til fremstilling af krystallinsk natrium og kaliumindomethacin og trihydrater deraf |
Country Status (3)
| Country | Link |
|---|---|
| EP (1) | EP0006223A1 (da) |
| JP (1) | JPS55396A (da) |
| DK (1) | DK244179A (da) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0248526A (ja) * | 1988-08-08 | 1990-02-19 | Sumitomo Pharmaceut Co Ltd | インドメタシン注射剤およびその製造方法 |
| US5466824A (en) * | 1989-05-22 | 1995-11-14 | Biochemical Veterinary Research Pty. Ltd. | Divalent metal complexes of indomethacin, compositions and medical methods of use thereof |
| CA2058754C (en) * | 1989-05-22 | 2002-02-19 | Hubertus L. Regtop | Divalent metal salts of indomethacin |
| FR2758819B1 (fr) * | 1997-01-29 | 2000-01-21 | Laprophan Laboratoires Pharma | Indometacine calcique et sa preparation |
| CN111848487A (zh) * | 2020-08-05 | 2020-10-30 | 河南优凯制药有限公司 | 一种吲哚美辛的纯化方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1232150B (de) * | 1961-03-22 | 1967-01-12 | Merck & Co Inc | Verfahren zur Herstellung von Indolyl-(3)-alkancarbonsaeuren und ihren Salzen |
| AT290523B (de) * | 1962-01-05 | 1971-06-11 | Merck & Co Inc | Verfahren zur Herstellung neuer α-(3-Indolyl)-carbonsäuren |
| DE1770157C3 (de) * | 1967-04-11 | 1975-01-16 | Sumitomo Chemical Co., Ltd., Osaka (Japan) | Argininsalz der l-p-Chlorbenzoyl-2-methyl-5-methoxy-3-indolylessigsäure |
| US3845210A (en) * | 1968-05-09 | 1974-10-29 | Y Mito | Solid composition comprising indolylaliphatic acid derivatives for forming an injection |
-
1979
- 1979-06-12 DK DK244179A patent/DK244179A/da not_active Application Discontinuation
- 1979-06-13 EP EP79101926A patent/EP0006223A1/en not_active Withdrawn
- 1979-06-13 JP JP7361779A patent/JPS55396A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JPS55396A (en) | 1980-01-05 |
| EP0006223A1 (en) | 1980-01-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ATS | Application withdrawn |