DK128781B - Analogifremgangsmåde til fremstilling af 2-(5-nitro-2-furyl)-thieno[3,2-d]-pyrimidiner. - Google Patents

Analogifremgangsmåde til fremstilling af 2-(5-nitro-2-furyl)-thieno[3,2-d]-pyrimidiner.

Info

Publication number
DK128781B
DK128781B DK601570AA DK601570A DK128781B DK 128781 B DK128781 B DK 128781B DK 601570A A DK601570A A DK 601570AA DK 601570 A DK601570 A DK 601570A DK 128781 B DK128781 B DK 128781B
Authority
DK
Denmark
Prior art keywords
thieno
pyrimidines
furyl
nitro
preparation
Prior art date
Application number
DK601570AA
Other languages
Danish (da)
English (en)
Inventor
E Woitun
W Reuter
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19691959403 external-priority patent/DE1959403A1/de
Priority claimed from DE19702050814 external-priority patent/DE2050814A1/de
Priority claimed from DE19702050816 external-priority patent/DE2050816A1/de
Priority claimed from DE19702050815 external-priority patent/DE2050815A1/de
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of DK128781B publication Critical patent/DK128781B/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
DK601570AA 1969-11-26 1970-11-25 Analogifremgangsmåde til fremstilling af 2-(5-nitro-2-furyl)-thieno[3,2-d]-pyrimidiner. DK128781B (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE19691959403 DE1959403A1 (de) 1969-11-26 1969-11-26 Neue 2-(5-Nitro-2-furyl)-thieno[3,2-d]pyrimidine und Verfahren zu ihrer Herstellung
DE19702050814 DE2050814A1 (de) 1970-10-16 1970-10-16 Neue Verfahren zur Herstellung von 2-(5-Nitro-2-furyl)-thieno eckige Klammer auf 3,2-d eckige Klammer zu pyrimidinen
DE19702050816 DE2050816A1 (de) 1970-10-16 1970-10-16 Neue 2-(Nitro-2-furyl>thieno eckige Klammer auf 3,2-d eckige Klammer zu pyrimidine
DE19702050815 DE2050815A1 (de) 1970-10-16 1970-10-16 Neue 2-(5-Nitro-2-furyl)-thieno eckige Klammer auf 3,2-d eckige Klammer zu pyrimidine

Publications (1)

Publication Number Publication Date
DK128781B true DK128781B (da) 1974-07-01

Family

ID=27430978

Family Applications (1)

Application Number Title Priority Date Filing Date
DK601570AA DK128781B (da) 1969-11-26 1970-11-25 Analogifremgangsmåde til fremstilling af 2-(5-nitro-2-furyl)-thieno[3,2-d]-pyrimidiner.

Country Status (13)

Country Link
US (1) US3661908A (xx)
BE (1) BE759493A (xx)
BG (2) BG17800A3 (xx)
CA (1) CA926865A (xx)
CH (3) CH559210A5 (xx)
DK (1) DK128781B (xx)
FR (1) FR2073416B1 (xx)
GB (1) GB1321316A (xx)
IE (1) IE34765B1 (xx)
IL (1) IL35729A (xx)
NL (1) NL7017210A (xx)
NO (1) NO129954B (xx)
SE (1) SE377938B (xx)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3932642A (en) * 1971-04-10 1976-01-13 Boehringer Ingelheim Gmbh Biocidal compositions containing a 2- (5'-nitro-2'-furyl)-thieno(2,3-d) pyrimidine and methods of use
US6187777B1 (en) 1998-02-06 2001-02-13 Amgen Inc. Compounds and methods which modulate feeding behavior and related diseases
US6608053B2 (en) * 2000-04-27 2003-08-19 Yamanouchi Pharmaceutical Co., Ltd. Fused heteroaryl derivatives
US20040138238A1 (en) * 2002-08-08 2004-07-15 Dhanoa Dale S. Substituted aminopyrimidine compounds as neurokinin antagonists
GB0423653D0 (en) 2004-10-25 2004-11-24 Piramed Ltd Pharmaceutical compounds
US7846929B2 (en) 2006-04-26 2010-12-07 Genentech, Inc. Phosphoinositide 3-kinase inhibitor compounds and methods of use
CL2007001167A1 (es) 2006-04-26 2008-01-25 Genentech Inc Compuestos derivados de pirimidina condensada, inhibidores de p13-quinasa; procesos para preparar los compuestos; composicion farmaceutica que los comprende; uso de los compuestos en la preparacion de medicamentos; proceso para preparar la composicion farmaceutica; y kit que incluye a la composicionfarmaceutica.
CL2007001165A1 (es) * 2006-04-26 2008-01-25 Hoffmann La Roche 2-(1h-indazol-4-il)-6-(4-metanosulfonil-piperazin-1-ilmetil)-4-morfolin-4-il-tieno[3,2-d]pirimidina; procedimiento de preparacion; composicion farmaceutica; proceso de preparacion de dicha composicion; kit farmaceutico; y uso para tratar enfermedades tales como cancer, desordenes inmunes y enfermedades cardiovasculares.
KR101507182B1 (ko) * 2006-12-07 2015-03-30 제넨테크, 인크. 포스포이노시타이드 3-키나제 억제제 화합물 및 그의 사용 방법
KR101460816B1 (ko) 2006-12-07 2014-11-12 에프. 호프만-라 로슈 아게 포스포이노시타이드 3-키나제 억제제 화합물 및 그의 사용 방법
WO2008152390A1 (en) * 2007-06-12 2008-12-18 F.Hoffmann-La Roche Ag Thiazoliopyrimidines and their use as inhibitors of phosphatidylinositol-3 kinase
ES2399774T3 (es) * 2007-09-24 2013-04-03 Genentech, Inc. Compuestos de tiazolopirimidina inhibidores de PI3K y métodos de uso
US8354528B2 (en) 2007-10-25 2013-01-15 Genentech, Inc. Process for making thienopyrimidine compounds
GB0721095D0 (en) * 2007-10-26 2007-12-05 Piramed Ltd Pharmaceutical compounds
JP5709766B2 (ja) 2009-03-12 2015-04-30 ジェネンテック， インコーポレイテッド 造血器腫瘍の治療のためのホスホイノシチド３キナーゼ阻害剤化合物と化学療法剤の併用
CA2761445A1 (en) 2009-05-27 2010-12-02 Genentech, Inc. Bicyclic pyrimidine pi3k inhibitor compounds selective for p110 delta, and methods of use
US8158625B2 (en) * 2009-05-27 2012-04-17 Genentech, Inc. Bicyclic indole-pyrimidine PI3K inhibitor compounds selective for P110 delta, and methods of use
NZ599939A (en) * 2009-10-12 2014-02-28 Hoffmann La Roche Combinations of a pi3k inhibitor and a mek inhibitor
MX2012011887A (es) 2010-04-16 2012-11-30 Genentech Inc Foxo 3a como biomarcador predictivo para la eficacia del inhibidor de la via de quinasa pi3k/akt.
US20140004209A1 (en) 2010-12-22 2014-01-02 Genentech, Inc. Autophagy inducer and inhibitor combination therapy for the treatment of neoplasms
JP6669500B2 (ja) 2013-02-25 2020-03-18 ジェネンテック， インコーポレイテッド 薬物耐性ａｋｔ変異体を検出し治療するための方法及び組成物

Also Published As

Publication number Publication date
US3661908A (en) 1972-05-09
CH567029A5 (xx) 1975-09-30
IL35729A (en) 1974-01-14
FR2073416A1 (xx) 1971-10-01
CA926865A (en) 1973-05-22
FR2073416B1 (xx) 1975-04-18
IL35729A0 (en) 1971-01-28
BG17799A3 (xx) 1973-12-25
NO129954B (xx) 1974-06-17
SE377938B (xx) 1975-08-04
BE759493A (fr) 1971-05-25
CH559210A5 (xx) 1975-02-28
GB1321316A (en) 1973-06-27
IE34765L (en) 1971-05-26
BG17800A3 (xx) 1973-12-25
NL7017210A (xx) 1971-05-28
CH568324A5 (xx) 1975-10-31
IE34765B1 (en) 1975-08-06

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