DK127060B - Analogifremgangsmåde til fremstilling af terapeutisk værdifulde 0-benzyloximderivater af 1-o-formyl-eller 1-o-acetyl-phenoxy-2-hydroxy 3-isopropylaminopropan eller ikke toksiske syreadditionssalte deraf. - Google Patents
Analogifremgangsmåde til fremstilling af terapeutisk værdifulde 0-benzyloximderivater af 1-o-formyl-eller 1-o-acetyl-phenoxy-2-hydroxy 3-isopropylaminopropan eller ikke toksiske syreadditionssalte deraf.Info
- Publication number
- DK127060B DK127060B DK224468AA DK224468A DK127060B DK 127060 B DK127060 B DK 127060B DK 224468A A DK224468A A DK 224468AA DK 224468 A DK224468 A DK 224468A DK 127060 B DK127060 B DK 127060B
- Authority
- DK
- Denmark
- Prior art keywords
- isopropylaminopropane
- benzyloxime
- formyl
- phenoxy
- acetyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
- C07D213/53—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
- C07C251/72—Hydrazones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/004—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reaction with organometalhalides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/27—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation
- C07C45/29—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation of hydroxy groups
- C07C45/292—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation of hydroxy groups with chromium derivatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/51—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
- C07C45/54—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition of compounds containing doubly bound oxygen atoms, e.g. esters
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/673—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/84—Ketones containing a keto group bound to a six-membered aromatic ring containing ether groups, groups, groups, or groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
- C07D213/46—Oxygen atoms
- C07D213/50—Ketonic radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
- C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
- C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
- C07D303/22—Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
- C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
- C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
- C07D303/24—Ethers with hydroxy compounds containing no oxirane rings with polyhydroxy compounds
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB2273567 | 1967-05-16 | ||
| GB5851667 | 1967-12-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK127060B true DK127060B (da) | 1973-09-17 |
Family
ID=26256090
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK224468AA DK127060B (da) | 1967-05-16 | 1968-05-14 | Analogifremgangsmåde til fremstilling af terapeutisk værdifulde 0-benzyloximderivater af 1-o-formyl-eller 1-o-acetyl-phenoxy-2-hydroxy 3-isopropylaminopropan eller ikke toksiske syreadditionssalte deraf. |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US3875149A (no) |
| AT (2) | AT286262B (no) |
| BE (1) | BE715205A (no) |
| CH (1) | CH489467A (no) |
| DE (1) | DE1768468A1 (no) |
| DK (1) | DK127060B (no) |
| ES (1) | ES353917A1 (no) |
| FR (2) | FR7616M (no) |
| GB (1) | GB1231783A (no) |
| IE (1) | IE32174B1 (no) |
| IL (1) | IL30001A (no) |
| IS (1) | IS860B6 (no) |
| MT (1) | MTP557B (no) |
| NL (1) | NL6806946A (no) |
| NO (1) | NO125183B (no) |
| SE (1) | SE369894B (no) |
| SU (1) | SU449484A3 (no) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1501632A (en) * | 1974-06-28 | 1978-02-22 | Cm Ind | Aromatic ketones having cardiovascular activity |
| US4201790A (en) * | 1975-06-20 | 1980-05-06 | May & Baker Limited | Benzophenone derivatives |
| JPS58116450A (ja) * | 1981-12-29 | 1983-07-11 | Nippon Soda Co Ltd | ５−フエニルシクロヘキセノン誘導体、その製造方法及び選択的除草剤 |
| DE3237400A1 (de) * | 1982-10-08 | 1984-04-12 | Bayer Ag, 5090 Leverkusen | Substituierte 1-hydroxyethyl-triazolyl-derivate |
| DE3309595A1 (de) * | 1983-03-17 | 1984-09-20 | Basf Ag, 6700 Ludwigshafen | Neue aminopropanolderivate von 1-(2-hydroxy-phenyl)-3-phenyl-propanolen, verfahren zu ihrer herstellung und diese enthaltende therapeutische mittel |
| FI832377A0 (fi) * | 1983-06-29 | 1983-06-29 | Star Oy Ab | Nytt foerfarande foer framstaellning av (r)-, (s)-eller (r,s)-1-(4'-alkylamido-2'-acetyl) fenoxi-3-alkylamino-2-propanoler |
| EP0309766B1 (en) * | 1987-09-29 | 1998-04-15 | Banyu Pharmaceutical Co., Ltd. | N-acylamino acid derivatives and their use |
| US6613942B1 (en) | 1997-07-01 | 2003-09-02 | Novo Nordisk A/S | Glucagon antagonists/inverse agonists |
| JP5070797B2 (ja) * | 2005-12-08 | 2012-11-14 | Ｊｎｃ株式会社 | 側方オキシラン化合物およびその重合体 |
| CA2673683C (en) | 2007-01-11 | 2014-07-29 | Critical Outcome Technologies, Inc. | Compounds and method for treatment of cancer |
| CA2710039C (en) | 2007-12-26 | 2018-07-03 | Critical Outcome Technologies, Inc. | Semicarbazones, thiosemicarbazones and related compounds and methods for treatment of cancer |
| WO2010006438A1 (en) | 2008-07-17 | 2010-01-21 | Critical Outcome Technologies Inc. | Thiosemicarbazone inhibitor compounds and cancer treatment methods |
| US8987272B2 (en) | 2010-04-01 | 2015-03-24 | Critical Outcome Technologies Inc. | Compounds and method for treatment of HIV |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2774766A (en) * | 1954-09-08 | 1956-12-18 | Hoffmann La Roche | Basic ethers |
| BE754604A (fr) * | 1969-08-08 | 1971-02-08 | Boehringer Sohn Ingelheim | Le 1-(2-nitrilophenoxy)-2-hydroxy-3-ethyl-aminopropane et ses sels |
-
1967
- 1967-05-16 GB GB2273567A patent/GB1231783A/en not_active Expired
-
1968
- 1968-05-13 SU SU1241053A patent/SU449484A3/ru active
- 1968-05-14 DK DK224468AA patent/DK127060B/da unknown
- 1968-05-14 IS IS1741A patent/IS860B6/is unknown
- 1968-05-14 NO NO1875/68A patent/NO125183B/no unknown
- 1968-05-14 SE SE06518/68A patent/SE369894B/xx unknown
- 1968-05-15 FR FR151932A patent/FR7616M/fr not_active Expired
- 1968-05-15 MT MT557A patent/MTP557B/xx unknown
- 1968-05-15 IL IL30001A patent/IL30001A/en unknown
- 1968-05-15 FR FR151931A patent/FR1570087A/fr not_active Expired
- 1968-05-15 BE BE715205D patent/BE715205A/xx unknown
- 1968-05-15 IE IE582/68A patent/IE32174B1/xx unknown
- 1968-05-16 AT AT470768A patent/AT286262B/de not_active IP Right Cessation
- 1968-05-16 CH CH722668A patent/CH489467A/fr not_active IP Right Cessation
- 1968-05-16 ES ES353917A patent/ES353917A1/es not_active Expired
- 1968-05-16 AT AT00822/70A patent/AT289826B/de not_active IP Right Cessation
- 1968-05-16 DE DE19681768468 patent/DE1768468A1/de active Pending
- 1968-05-16 NL NL6806946A patent/NL6806946A/xx unknown
-
1972
- 1972-12-19 US US316508A patent/US3875149A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| FR1570087A (fr) | 1969-06-06 |
| NO125183B (no) | 1972-07-31 |
| SE369894B (no) | 1974-09-23 |
| FR7616M (fr) | 1970-01-19 |
| IL30001A (en) | 1973-07-30 |
| AT286262B (de) | 1970-12-10 |
| IS1741A7 (is) | 1968-11-17 |
| IE32174L (en) | 1968-11-16 |
| CH489467A (fr) | 1970-04-30 |
| AT289826B (de) | 1971-03-15 |
| SU443509A3 (ru) | 1974-09-15 |
| IL30001A0 (en) | 1968-07-25 |
| IS860B6 (is) | 1974-05-22 |
| SU449484A3 (ru) | 1974-11-05 |
| DE1768468A1 (de) | 1971-07-01 |
| NL6806946A (no) | 1968-11-18 |
| MTP557B (en) | 1969-01-04 |
| US3875149A (en) | 1975-04-01 |
| GB1231783A (en) | 1971-05-12 |
| BE715205A (fr) | 1968-11-18 |
| ES353917A1 (es) | 1969-10-16 |
| IE32174B1 (en) | 1973-05-02 |
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