DK120998B - Analogifremgangsmåde til fremstilling af piperazinderivater eller syreadditionssalte deraf. - Google Patents

Analogifremgangsmåde til fremstilling af piperazinderivater eller syreadditionssalte deraf.

Info

Publication number
DK120998B
DK120998B DK309268AA DK309268A DK120998B DK 120998 B DK120998 B DK 120998B DK 309268A A DK309268A A DK 309268AA DK 309268 A DK309268 A DK 309268A DK 120998 B DK120998 B DK 120998B
Authority
DK
Denmark
Prior art keywords
preparation
acid addition
addition salts
piperazine derivatives
analogous process
Prior art date
Application number
DK309268AA
Other languages
English (en)
Inventor
P Bysouth
R Clarke
Original Assignee
British Drug Houses Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by British Drug Houses Ltd filed Critical British Drug Houses Ltd
Publication of DK120998B publication Critical patent/DK120998B/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/06Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals
    • C07D295/073Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals with the ring nitrogen atoms and the substituents separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C17/00Preparation of halogenated hydrocarbons
    • C07C17/093Preparation of halogenated hydrocarbons by replacement by halogens
    • C07C17/10Preparation of halogenated hydrocarbons by replacement by halogens of hydrogen atoms
    • C07C17/12Preparation of halogenated hydrocarbons by replacement by halogens of hydrogen atoms in the ring of aromatic compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/092Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings with aromatic radicals attached to the chain
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D303/00Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02Compounds containing oxirane rings
    • C07D303/04Compounds containing oxirane rings containing only hydrogen and carbon atoms in addition to the ring oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK309268AA 1967-07-05 1968-06-27 Analogifremgangsmåde til fremstilling af piperazinderivater eller syreadditionssalte deraf. DK120998B (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB30873/67A GB1171251A (en) 1967-07-05 1967-07-05 Preparation of Piperazine Derivatives

Publications (1)

Publication Number Publication Date
DK120998B true DK120998B (da) 1971-08-16

Family

ID=10314465

Family Applications (1)

Application Number Title Priority Date Filing Date
DK309268AA DK120998B (da) 1967-07-05 1968-06-27 Analogifremgangsmåde til fremstilling af piperazinderivater eller syreadditionssalte deraf.

Country Status (13)

Country Link
US (1) US3732229A (da)
AT (1) AT281038B (da)
CH (1) CH496005A (da)
DE (1) DE1770805A1 (da)
DK (1) DK120998B (da)
ES (1) ES355739A1 (da)
FR (1) FR1583999A (da)
GB (1) GB1171251A (da)
IE (1) IE32152B1 (da)
IL (1) IL30313A (da)
NL (1) NL6809422A (da)
NO (1) NO126082B (da)
SE (1) SE352891B (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2081557B1 (da) * 1970-03-02 1973-08-10 Cerm Cent Europ Rech Mauvernay
US3951978A (en) * 1972-04-22 1976-04-20 Istituto Luso Farmaco D'italia S.R.L. 1,3-Disubstituted 3-aroylpropanes and process for the preparation thereof
DE2246279A1 (de) * 1972-09-21 1974-05-22 Goedecke Ag Neue 1-aryl-2-arylalkyl-3-(4)-eckige klammer auf 4'-(subst.-alkyl)-piperazino1' eckige klammer zu -butanole-2 bzw. butene-1 und verfahren zu ihrer herstellung
GB9308725D0 (en) * 1993-04-27 1993-06-09 Wyeth John & Brother Ltd Piperazine derivatives
AU2868601A (en) * 2000-01-27 2001-08-07 Ribotargets Ltd Biaryl compounds, their preparation and their use in therapy
JO2857B1 (en) * 2008-06-16 2015-03-15 سانوفي أفينتس Vinyl pipers with modified activity of tumor-resistant TNF

Also Published As

Publication number Publication date
IL30313A (en) 1972-08-30
IE32152L (en) 1969-01-05
US3732229A (en) 1973-05-08
FR1583999A (da) 1969-12-12
NL6809422A (da) 1969-01-07
GB1171251A (en) 1969-11-19
NO126082B (da) 1972-12-18
SE352891B (da) 1973-01-15
IL30313A0 (en) 1968-09-26
IE32152B1 (en) 1973-05-02
AT281038B (de) 1970-05-11
DE1770805A1 (de) 1972-01-13
CH496005A (de) 1970-09-15
ES355739A1 (es) 1969-12-16

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