AT281038B - Verfahren zur Herstellung von neuen Piperazinderivaten und ihren Salzen - Google Patents

Verfahren zur Herstellung von neuen Piperazinderivaten und ihren Salzen

Info

Publication number
AT281038B
AT281038B AT639368A AT639368A AT281038B AT 281038 B AT281038 B AT 281038B AT 639368 A AT639368 A AT 639368A AT 639368 A AT639368 A AT 639368A AT 281038 B AT281038 B AT 281038B
Authority
AT
Austria
Prior art keywords
salts
preparation
piperazine derivatives
new piperazine
new
Prior art date
Application number
AT639368A
Other languages
English (en)
Original Assignee
British Drug Houses Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by British Drug Houses Ltd filed Critical British Drug Houses Ltd
Application granted granted Critical
Publication of AT281038B publication Critical patent/AT281038B/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/06—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals
    • C07D295/073—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals with the ring nitrogen atoms and the substituents separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C17/00—Preparation of halogenated hydrocarbons
    • C07C17/093—Preparation of halogenated hydrocarbons by replacement by halogens
    • C07C17/10—Preparation of halogenated hydrocarbons by replacement by halogens of hydrogen atoms
    • C07C17/12—Preparation of halogenated hydrocarbons by replacement by halogens of hydrogen atoms in the ring of aromatic compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/092—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings with aromatic radicals attached to the chain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/04—Compounds containing oxirane rings containing only hydrogen and carbon atoms in addition to the ring oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT639368A 1967-07-05 1968-07-03 Verfahren zur Herstellung von neuen Piperazinderivaten und ihren Salzen AT281038B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB30873/67A GB1171251A (en) 1967-07-05 1967-07-05 Preparation of Piperazine Derivatives

Publications (1)

Publication Number Publication Date
AT281038B true AT281038B (de) 1970-05-11

Family

ID=10314465

Family Applications (1)

Application Number Title Priority Date Filing Date
AT639368A AT281038B (de) 1967-07-05 1968-07-03 Verfahren zur Herstellung von neuen Piperazinderivaten und ihren Salzen

Country Status (13)

Country Link
US (1) US3732229A (de)
AT (1) AT281038B (de)
CH (1) CH496005A (de)
DE (1) DE1770805A1 (de)
DK (1) DK120998B (de)
ES (1) ES355739A1 (de)
FR (1) FR1583999A (de)
GB (1) GB1171251A (de)
IE (1) IE32152B1 (de)
IL (1) IL30313A (de)
NL (1) NL6809422A (de)
NO (1) NO126082B (de)
SE (1) SE352891B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2081557B1 (de) * 1970-03-02 1973-08-10 Cerm Cent Europ Rech Mauvernay
US3951978A (en) * 1972-04-22 1976-04-20 Istituto Luso Farmaco D'italia S.R.L. 1,3-Disubstituted 3-aroylpropanes and process for the preparation thereof
DE2246279A1 (de) * 1972-09-21 1974-05-22 Goedecke Ag Neue 1-aryl-2-arylalkyl-3-(4)-eckige klammer auf 4'-(subst.-alkyl)-piperazino1' eckige klammer zu -butanole-2 bzw. butene-1 und verfahren zu ihrer herstellung
GB9308725D0 (en) * 1993-04-27 1993-06-09 Wyeth John & Brother Ltd Piperazine derivatives
AU2868601A (en) * 2000-01-27 2001-08-07 Ribotargets Ltd Biaryl compounds, their preparation and their use in therapy
JO2857B1 (en) * 2008-06-16 2015-03-15 سانوفي أفينتس Vinyl pipers with modified activity of tumor-resistant TNF

Also Published As

Publication number Publication date
NL6809422A (de) 1969-01-07
IL30313A0 (en) 1968-09-26
IL30313A (en) 1972-08-30
FR1583999A (de) 1969-12-12
ES355739A1 (es) 1969-12-16
DE1770805A1 (de) 1972-01-13
IE32152B1 (en) 1973-05-02
SE352891B (de) 1973-01-15
US3732229A (en) 1973-05-08
GB1171251A (en) 1969-11-19
IE32152L (en) 1969-01-05
NO126082B (de) 1972-12-18
DK120998B (da) 1971-08-16
CH496005A (de) 1970-09-15

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Legal Events

Date Code Title Description
ELJ Ceased due to non-payment of the annual fee