DK1257552T3 - Xanthinderivater, mellemprodukter og anvendelse til behandling af osteoporose - Google Patents

Xanthinderivater, mellemprodukter og anvendelse til behandling af osteoporose

Info

Publication number
DK1257552T3
DK1257552T3 DK01907784T DK01907784T DK1257552T3 DK 1257552 T3 DK1257552 T3 DK 1257552T3 DK 01907784 T DK01907784 T DK 01907784T DK 01907784 T DK01907784 T DK 01907784T DK 1257552 T3 DK1257552 T3 DK 1257552T3
Authority
DK
Denmark
Prior art keywords
intermediates
osteoporosis
treatment
xanthine derivatives
derivatives
Prior art date
Application number
DK01907784T
Other languages
English (en)
Inventor
Jean-Paul Vevert
Guenter Johannes Billen
Yamina Bouali
Francois Nique
Yusuke Satoh
Original Assignee
Aventis Pharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa
Application granted granted Critical
Publication of DK1257552T3 publication Critical patent/DK1257552T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/18—Drugs for disorders of the endocrine system of the parathyroid hormones
    • A61P5/20—Drugs for disorders of the endocrine system of the parathyroid hormones for decreasing, blocking or antagonising the activity of PTH
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Physical Education & Sports Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK01907784T 2000-02-15 2001-02-14 Xanthinderivater, mellemprodukter og anvendelse til behandling af osteoporose DK1257552T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0001845A FR2804958B1 (fr) 2000-02-15 2000-02-15 Derives de xanthine, leur procede de preparation et les intermediaires de ce procede, leur application comme medicament et les compositions pharmaceutiques les renfermant
PCT/FR2001/000420 WO2001060824A1 (fr) 2000-02-15 2001-02-14 Derives de xanthine, intermediaires et application au traitement de l'osteoporose

Publications (1)

Publication Number Publication Date
DK1257552T3 true DK1257552T3 (da) 2004-12-20

Family

ID=8847004

Family Applications (1)

Application Number Title Priority Date Filing Date
DK01907784T DK1257552T3 (da) 2000-02-15 2001-02-14 Xanthinderivater, mellemprodukter og anvendelse til behandling af osteoporose

Country Status (9)

Country Link
EP (1) EP1257552B1 (da)
AT (1) ATE273979T1 (da)
AU (1) AU2001235668A1 (da)
DE (1) DE60104986T2 (da)
DK (1) DK1257552T3 (da)
ES (1) ES2227134T3 (da)
FR (1) FR2804958B1 (da)
PT (1) PT1257552E (da)
WO (1) WO2001060824A1 (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4491344B2 (ja) 2002-06-17 2010-06-30 グラクソ グループ リミテッド 肝ｘ受容体アゴニストとしてのプリン誘導体
US8193182B2 (en) 2008-01-04 2012-06-05 Intellikine, Inc. Substituted isoquinolin-1(2H)-ones, and methods of use thereof
AU2009204483B2 (en) 2008-01-04 2014-03-13 Intellikine, Llc Certain chemical entities, compositions and methods
BR112013017670B1 (pt) 2011-01-10 2022-07-19 Infinity Pharmaceuticals, Inc Processos de preparação de isoquinolinonas e formas sólidas de isoquinolinonas
US8828998B2 (en) 2012-06-25 2014-09-09 Infinity Pharmaceuticals, Inc. Treatment of lupus, fibrotic conditions, and inflammatory myopathies and other disorders using PI3 kinase inhibitors
WO2015003881A1 (en) * 2013-07-08 2015-01-15 Syngenta Participations Ag Microbiocidal heterobicyclic derivatives
US20150320755A1 (en) 2014-04-16 2015-11-12 Infinity Pharmaceuticals, Inc. Combination therapies
AU2017281797A1 (en) 2016-06-24 2019-01-24 Infinity Pharmaceuticals, Inc. Combination therapies
CN109503583A (zh) * 2018-12-14 2019-03-22 南京纽邦生物科技有限公司 1,7-二甲基黄嘌呤及其中间体的制备方法、中间体

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992006976A1 (fr) * 1990-10-18 1992-04-30 Kyowa Hakko Kogyo Co., Ltd. Derive de xanthine
WO1996036638A1 (en) * 1995-05-19 1996-11-21 Chiroscience Limited Xanthines and their therapeutic use
JPH09169665A (ja) * 1995-12-21 1997-06-30 Kenichi Miyamoto 骨粗鬆症治療剤
DE59708533D1 (de) * 1996-06-07 2002-11-28 Hoechst Ag Verwendung von Theophyllinderivaten zur Behandlung und Propylaxe von Schockzuständen, neue Xanthinverbindungen und Verfahren zu deren Herstellung
GB9703044D0 (en) * 1997-02-14 1997-04-02 Glaxo Group Ltd Phenyl xanthine esters and amides
JPH1192379A (ja) * 1997-07-24 1999-04-06 Kunio Takaoka 骨疾患の予防または治療剤

Also Published As

Publication number Publication date
EP1257552B1 (fr) 2004-08-18
DE60104986D1 (de) 2004-09-23
ATE273979T1 (de) 2004-09-15
AU2001235668A1 (en) 2001-08-27
PT1257552E (pt) 2005-01-31
FR2804958A1 (fr) 2001-08-17
WO2001060824A1 (fr) 2001-08-23
ES2227134T3 (es) 2005-04-01
DE60104986T2 (de) 2005-08-25
FR2804958B1 (fr) 2005-07-08
EP1257552A1 (fr) 2002-11-20

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