DK1255747T3 - Syntese af 3,6-dialkyl-5,6-dihydro-4-hydroxy-pyran-2-on - Google Patents
Syntese af 3,6-dialkyl-5,6-dihydro-4-hydroxy-pyran-2-onInfo
- Publication number
- DK1255747T3 DK1255747T3 DK01909697T DK01909697T DK1255747T3 DK 1255747 T3 DK1255747 T3 DK 1255747T3 DK 01909697 T DK01909697 T DK 01909697T DK 01909697 T DK01909697 T DK 01909697T DK 1255747 T3 DK1255747 T3 DK 1255747T3
- Authority
- DK
- Denmark
- Prior art keywords
- pyran
- dialkyl
- dihydro
- hydroxy
- synthesis
- Prior art date
Links
- 230000015572 biosynthetic process Effects 0.000 title 1
- 238000003786 synthesis reaction Methods 0.000 title 1
- 150000001266 acyl halides Chemical class 0.000 abstract 1
- 125000000422 delta-lactone group Chemical group 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F3/00—Compounds containing elements of Groups 2 or 12 of the Periodic Table
- C07F3/02—Magnesium compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
- C07C67/31—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by introduction of functional groups containing oxygen only in singly bound form
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
- C07D305/02—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms not condensed with other rings
- C07D305/10—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms not condensed with other rings having one or more double bonds between ring members or between ring members and non-ring members
- C07D305/12—Beta-lactones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/32—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyrane Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US18056000P | 2000-02-04 | 2000-02-04 | |
PCT/EP2001/000866 WO2001057014A2 (en) | 2000-02-04 | 2001-01-26 | Synthesis of 3,6-dialkyl-5,6-dihydro-4-hydroxy-pyran-2-one |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1255747T3 true DK1255747T3 (da) | 2007-02-12 |
Family
ID=22660904
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK01909697T DK1255747T3 (da) | 2000-02-04 | 2001-01-26 | Syntese af 3,6-dialkyl-5,6-dihydro-4-hydroxy-pyran-2-on |
Country Status (14)
Country | Link |
---|---|
US (4) | US6545165B1 (zh) |
EP (1) | EP1255747B1 (zh) |
JP (1) | JP4097943B2 (zh) |
KR (1) | KR100516242B1 (zh) |
CN (2) | CN100355740C (zh) |
AT (1) | ATE341541T1 (zh) |
AU (1) | AU2001237347A1 (zh) |
CA (1) | CA2397232C (zh) |
DE (1) | DE60123579T2 (zh) |
DK (1) | DK1255747T3 (zh) |
ES (1) | ES2272446T3 (zh) |
JO (1) | JO2243B1 (zh) |
MX (1) | MXPA02007520A (zh) |
WO (1) | WO2001057014A2 (zh) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2005272033A1 (en) * | 2004-07-08 | 2006-02-16 | Merck & Co., Inc. | Formation of tetra-substituted enamides and stereoselective reduction thereof |
MX2007014494A (es) * | 2005-05-24 | 2008-02-11 | Hoffmann La Roche | Preparaciones de (s)-4-fluorometil-dihidro-furan-2-ona. |
CN101460461B (zh) * | 2006-04-03 | 2012-10-03 | 弗·哈夫曼-拉罗切有限公司 | 对映体富集的环β-芳基或杂芳基羧酸的制备方法 |
EP2069343A2 (en) * | 2006-09-15 | 2009-06-17 | F. Hoffmann-Roche AG | Process for the preparation of pyrido[2,1-a]isoquinoline derivatives by catalytic asymmetric hydrogenation of an enamine |
KR101076680B1 (ko) * | 2007-11-01 | 2011-10-26 | 한미홀딩스 주식회사 | (6r)-3-헥실-4-히드록시-6-운데실-5,6-다이히드로피란-2-온의 제조방법 및 이에 사용되는 중간체 |
KR101126084B1 (ko) * | 2008-11-04 | 2012-03-29 | 한미홀딩스 주식회사 | (3s,4s)-4-((r)-2-(벤질옥시)트라이데실)-3-헥실-2-옥세타논의 제조방법 및 이에 사용되는 중간체 |
EP2379500A1 (en) * | 2008-12-16 | 2011-10-26 | F. Hoffmann-La Roche AG | Process for the preparation of pyrollidine-3-carboxylic acids |
WO2010069778A1 (en) * | 2008-12-18 | 2010-06-24 | F. Hoffmann-La Roche Ag | Process for synthesis of amino-methyl tetraline derivatives |
US20110040091A1 (en) * | 2009-08-13 | 2011-02-17 | Stephan Bachmann | Process for the preparation of (r)-2-phenyl propionic acid derivatives |
US20110054174A1 (en) | 2009-08-28 | 2011-03-03 | Stephan Bachmann | Process for the preparation of a glucokinase activator compound |
KR101106603B1 (ko) * | 2009-11-24 | 2012-01-20 | 허성환 | 하이브리드형 낙뢰보호 장치 |
JP5915486B2 (ja) * | 2012-09-28 | 2016-05-11 | Jsr株式会社 | フォトレジスト組成物、レジストパターン形成方法及び重合体 |
US9163202B2 (en) | 2013-08-02 | 2015-10-20 | Eastman Chemical Company | Aqueous cleaning compositions including an alkyl 3-hydroxybutyrate |
US9388114B2 (en) | 2013-08-02 | 2016-07-12 | Eastman Chemical Company | Compositions including an alkyl 3-hydroxybutyrate |
US9255059B2 (en) | 2013-08-02 | 2016-02-09 | Eastman Chemical Company | Method for producing an alkyl 3-hydroxybutyrate |
US9249378B2 (en) | 2013-08-02 | 2016-02-02 | Eastman Chemical Company | Aqueous cleaning compositions having enhanced properties |
RU2702355C1 (ru) | 2013-11-15 | 2019-10-08 | Ф. Хоффманн-Ля Рош Аг | Способ получения пиримидинилциклопентановых соединений |
CN110734420A (zh) * | 2019-12-04 | 2020-01-31 | 重庆植恩药业有限公司 | 一种奥利司他杂质f及其制备方法和用途 |
CN115974634B (zh) * | 2023-02-15 | 2023-11-28 | 瑞博(苏州)制药有限公司 | 不对称催化氢化制备沙库巴曲化合物的方法 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4962242A (en) | 1986-08-27 | 1990-10-09 | Takasago Perfumery Co., Ltd. | Process for producing optically active alcohols |
DE3778857D1 (de) * | 1986-11-14 | 1992-06-11 | Takasago Perfumery Co Ltd | Katalytische produktion von optisch aktiven carbonsaeuren. |
JPH064544B2 (ja) | 1987-06-19 | 1994-01-19 | 高砂香料工業株式会社 | 光学活性アルコ−ルの製造方法 |
CA2035972C (en) | 1990-02-23 | 2006-07-11 | Martin Karpf | Process for the preparation of oxetanones |
JPH04264054A (ja) | 1990-10-15 | 1992-09-18 | Lonza Ag | 3−オキソカルボン酸エステルの製造方法 |
DE4116906A1 (de) | 1991-05-23 | 1992-11-26 | Wacker Chemie Gmbh | Verfahren zur herstellung von (beta)-ketocarbonsaeureestern |
US5274143A (en) | 1991-07-23 | 1993-12-28 | Hoffmann-La Roche Inc. | Process for the preparation of (R)-3-hexyl-5,6-dihydro-4-hydroxy-6-undecyl-2H-pyran-2-one and (R)-5,6-dihydro-6-undecyl-2H-pyran-2,4(3H)-dione |
JP3251525B2 (ja) | 1996-05-24 | 2002-01-28 | 高砂香料工業株式会社 | 3−オキソカルボン酸エステルの製造方法 |
-
2000
- 2000-09-22 US US09/668,834 patent/US6545165B1/en not_active Expired - Lifetime
-
2001
- 2001-01-04 JO JO20014A patent/JO2243B1/en active
- 2001-01-26 DE DE60123579T patent/DE60123579T2/de not_active Expired - Lifetime
- 2001-01-26 CN CNB2005100709339A patent/CN100355740C/zh not_active Expired - Lifetime
- 2001-01-26 EP EP01909697A patent/EP1255747B1/en not_active Expired - Lifetime
- 2001-01-26 DK DK01909697T patent/DK1255747T3/da active
- 2001-01-26 CN CNB01804431XA patent/CN1239493C/zh not_active Expired - Lifetime
- 2001-01-26 ES ES01909697T patent/ES2272446T3/es not_active Expired - Lifetime
- 2001-01-26 CA CA002397232A patent/CA2397232C/en not_active Expired - Lifetime
- 2001-01-26 WO PCT/EP2001/000866 patent/WO2001057014A2/en active IP Right Grant
- 2001-01-26 MX MXPA02007520A patent/MXPA02007520A/es active IP Right Grant
- 2001-01-26 AT AT01909697T patent/ATE341541T1/de active
- 2001-01-26 AU AU2001237347A patent/AU2001237347A1/en not_active Abandoned
- 2001-01-26 KR KR10-2002-7010000A patent/KR100516242B1/ko active IP Right Grant
- 2001-01-26 JP JP2001556864A patent/JP4097943B2/ja not_active Expired - Lifetime
-
2003
- 2003-02-10 US US10/364,536 patent/US6858749B2/en not_active Expired - Lifetime
- 2003-02-10 US US10/364,692 patent/US6818789B2/en not_active Expired - Lifetime
- 2003-02-10 US US10/364,547 patent/US6743927B2/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
KR100516242B1 (ko) | 2005-09-20 |
JO2243B1 (en) | 2004-10-07 |
JP4097943B2 (ja) | 2008-06-11 |
WO2001057014A2 (en) | 2001-08-09 |
US6545165B1 (en) | 2003-04-08 |
CN1239493C (zh) | 2006-02-01 |
CA2397232A1 (en) | 2001-08-09 |
DE60123579D1 (de) | 2006-11-16 |
US20030171602A1 (en) | 2003-09-11 |
US6818789B2 (en) | 2004-11-16 |
EP1255747A2 (en) | 2002-11-13 |
EP1255747B1 (en) | 2006-10-04 |
CN1680347A (zh) | 2005-10-12 |
KR20030005180A (ko) | 2003-01-17 |
ES2272446T3 (es) | 2007-05-01 |
CN100355740C (zh) | 2007-12-19 |
US20030158423A1 (en) | 2003-08-21 |
AU2001237347A1 (en) | 2001-08-14 |
CN1396919A (zh) | 2003-02-12 |
CA2397232C (en) | 2007-01-23 |
US6743927B2 (en) | 2004-06-01 |
DE60123579T2 (de) | 2007-06-21 |
WO2001057014A3 (en) | 2002-04-18 |
MXPA02007520A (es) | 2002-12-13 |
JP2003521546A (ja) | 2003-07-15 |
US6858749B2 (en) | 2005-02-22 |
ATE341541T1 (de) | 2006-10-15 |
US20030158422A1 (en) | 2003-08-21 |
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