DK1237847T3 - Fremgangsmåde til stereoselektiv syntese af cyckliske aminosyrer - Google Patents
Fremgangsmåde til stereoselektiv syntese af cyckliske aminosyrerInfo
- Publication number
- DK1237847T3 DK1237847T3 DK00980881T DK00980881T DK1237847T3 DK 1237847 T3 DK1237847 T3 DK 1237847T3 DK 00980881 T DK00980881 T DK 00980881T DK 00980881 T DK00980881 T DK 00980881T DK 1237847 T3 DK1237847 T3 DK 1237847T3
- Authority
- DK
- Denmark
- Prior art keywords
- amino acids
- cyclic amino
- stereoselective synthesis
- stereoselective
- synthesis
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/12—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/30—Preparation of optical isomers
- C07C227/32—Preparation of optical isomers by stereospecific synthesis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/28—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and containing rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/01—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
- C07C255/31—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing rings other than six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/01—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
- C07C255/32—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring
- C07C255/41—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring the carbon skeleton being further substituted by carboxyl groups, other than cyano groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C265/00—Derivatives of isocyanic acid
- C07C265/02—Derivatives of isocyanic acid having isocyanate groups bound to acyclic carbon atoms
- C07C265/06—Derivatives of isocyanic acid having isocyanate groups bound to acyclic carbon atoms of an unsaturated carbon skeleton
- C07C265/08—Derivatives of isocyanic acid having isocyanate groups bound to acyclic carbon atoms of an unsaturated carbon skeleton the carbon skeleton containing rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/08—Preparation of carboxylic acids or their salts, halides or anhydrides from nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/41—Preparation of salts of carboxylic acids
- C07C51/412—Preparation of salts of carboxylic acids by conversion of the acids, their salts, esters or anhydrides with the same carboxylic acid part
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/42—Separation; Purification; Stabilisation; Use of additives
- C07C51/43—Separation; Purification; Stabilisation; Use of additives by change of the physical state, e.g. crystallisation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/608—Esters of carboxylic acids having a carboxyl group bound to an acyclic carbon atom and having a ring other than a six-membered aromatic ring in the acid moiety
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/612—Esters of carboxylic acids having a carboxyl group bound to an acyclic carbon atom and having a six-membered aromatic ring in the acid moiety
- C07C69/616—Esters of carboxylic acids having a carboxyl group bound to an acyclic carbon atom and having a six-membered aromatic ring in the acid moiety polycyclic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
- C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Neurosurgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pain & Pain Management (AREA)
- Crystallography & Structural Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US16960299P | 1999-12-08 | 1999-12-08 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1237847T3 true DK1237847T3 (da) | 2006-09-04 |
Family
ID=22616383
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK00980881T DK1237847T3 (da) | 1999-12-08 | 2000-11-30 | Fremgangsmåde til stereoselektiv syntese af cyckliske aminosyrer |
Country Status (24)
| Country | Link |
|---|---|
| EP (1) | EP1237847B1 (da) |
| JP (1) | JP2003516378A (da) |
| KR (1) | KR20020060988A (da) |
| CN (2) | CN1407967A (da) |
| AR (1) | AR032433A1 (da) |
| AT (1) | ATE326443T1 (da) |
| AU (1) | AU1808401A (da) |
| BR (1) | BR0016201A (da) |
| CA (1) | CA2392761A1 (da) |
| CO (1) | CO5280085A1 (da) |
| DE (1) | DE60028076T2 (da) |
| DK (1) | DK1237847T3 (da) |
| EA (1) | EA004984B1 (da) |
| ES (1) | ES2264424T3 (da) |
| HU (1) | HUP0203812A3 (da) |
| IL (1) | IL149575A0 (da) |
| MX (1) | MXPA02004829A (da) |
| PE (1) | PE20010927A1 (da) |
| PL (1) | PL355787A1 (da) |
| PT (1) | PT1237847E (da) |
| UY (1) | UY26475A1 (da) |
| WO (1) | WO2001042190A1 (da) |
| YU (1) | YU41602A (da) |
| ZA (1) | ZA200203628B (da) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE390133T1 (de) | 2000-06-26 | 2008-04-15 | Warner Lambert Co | Gabapentinanaloga für schlafstörungen |
| AR031473A1 (es) * | 2000-11-20 | 2003-09-24 | Lundbeck & Co As H | Intensificadores de gaba en el tratamiento de enfermedades relacionadas con una reducida actividad neuroesteroide |
| US6818787B2 (en) | 2001-06-11 | 2004-11-16 | Xenoport, Inc. | Prodrugs of GABA analogs, compositions and uses thereof |
| US8048917B2 (en) | 2005-04-06 | 2011-11-01 | Xenoport, Inc. | Prodrugs of GABA analogs, compositions and uses thereof |
| US7186855B2 (en) | 2001-06-11 | 2007-03-06 | Xenoport, Inc. | Prodrugs of GABA analogs, compositions and uses thereof |
| CA2451267A1 (en) * | 2002-12-13 | 2004-06-13 | Warner-Lambert Company Llc | Pharmaceutical uses for alpha2delta ligands |
| PL377286A1 (pl) * | 2002-12-13 | 2006-01-23 | Warner-Lambert Company Llc | Analogi gabapentyny do włókniako-mięśniakowych i innych pokrewnych zaburzeń |
| CN101515737B (zh) * | 2008-02-20 | 2010-10-06 | 中国科学院工程热物理研究所 | 应用三甲基叠氮硅烷为发电机定子蒸发冷却介质的方法 |
| CN102557922A (zh) * | 2010-12-20 | 2012-07-11 | 上海药明康德新药开发有限公司 | 顺式-3-羟基-3-甲基环丁基甲酸的合成方法 |
| DE102010055499A1 (de) * | 2010-12-22 | 2011-06-16 | W.C. Heraeus Gmbh | Prozess zur Herstellung von Bendamustinalkylester, Bendarmustin sowie Derivaten davon |
| CN102249833B (zh) * | 2011-05-27 | 2013-12-11 | 中国科学院化学研究所 | 一种制备手性γ-氨基酸及其衍生物的方法 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR9813284B1 (pt) * | 1997-10-27 | 2012-08-21 | aminoácidos cìclicos e derivados dos mesmos úteis como agentes farmacêuticos e composição farmacêutica. |
-
2000
- 2000-11-30 IL IL14957500A patent/IL149575A0/xx unknown
- 2000-11-30 PL PL00355787A patent/PL355787A1/xx not_active Application Discontinuation
- 2000-11-30 CA CA002392761A patent/CA2392761A1/en not_active Abandoned
- 2000-11-30 ES ES00980881T patent/ES2264424T3/es not_active Expired - Lifetime
- 2000-11-30 HU HU0203812A patent/HUP0203812A3/hu unknown
- 2000-11-30 CN CN00816813A patent/CN1407967A/zh active Pending
- 2000-11-30 BR BR0016201-9A patent/BR0016201A/pt not_active IP Right Cessation
- 2000-11-30 EP EP00980881A patent/EP1237847B1/en not_active Expired - Lifetime
- 2000-11-30 AT AT00980881T patent/ATE326443T1/de not_active IP Right Cessation
- 2000-11-30 YU YU41602A patent/YU41602A/sh unknown
- 2000-11-30 AU AU18084/01A patent/AU1808401A/en not_active Abandoned
- 2000-11-30 EA EA200200463A patent/EA004984B1/ru not_active IP Right Cessation
- 2000-11-30 CN CNA2004100628430A patent/CN1607201A/zh active Pending
- 2000-11-30 DE DE60028076T patent/DE60028076T2/de not_active Expired - Fee Related
- 2000-11-30 MX MXPA02004829A patent/MXPA02004829A/es not_active Application Discontinuation
- 2000-11-30 PT PT00980881T patent/PT1237847E/pt unknown
- 2000-11-30 DK DK00980881T patent/DK1237847T3/da active
- 2000-11-30 JP JP2001543492A patent/JP2003516378A/ja active Pending
- 2000-11-30 WO PCT/US2000/032570 patent/WO2001042190A1/en not_active Application Discontinuation
- 2000-11-30 KR KR1020027007280A patent/KR20020060988A/ko not_active Application Discontinuation
- 2000-12-07 CO CO00093678A patent/CO5280085A1/es not_active Application Discontinuation
- 2000-12-07 AR ARP000106492A patent/AR032433A1/es unknown
- 2000-12-07 UY UY26475A patent/UY26475A1/es not_active Application Discontinuation
- 2000-12-07 PE PE2000001314A patent/PE20010927A1/es not_active Application Discontinuation
-
2002
- 2002-05-07 ZA ZA200203628A patent/ZA200203628B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE60028076D1 (de) | 2006-06-22 |
| ZA200203628B (en) | 2003-08-07 |
| PT1237847E (pt) | 2006-08-31 |
| ES2264424T3 (es) | 2007-01-01 |
| HUP0203812A3 (en) | 2004-12-28 |
| YU41602A (sh) | 2005-07-19 |
| KR20020060988A (ko) | 2002-07-19 |
| CA2392761A1 (en) | 2001-06-14 |
| CN1407967A (zh) | 2003-04-02 |
| IL149575A0 (en) | 2002-11-10 |
| EA004984B1 (ru) | 2004-10-28 |
| DE60028076T2 (de) | 2006-11-02 |
| PL355787A1 (en) | 2004-05-17 |
| ATE326443T1 (de) | 2006-06-15 |
| WO2001042190A1 (en) | 2001-06-14 |
| EA200200463A1 (ru) | 2002-12-26 |
| PE20010927A1 (es) | 2001-09-08 |
| EP1237847B1 (en) | 2006-05-17 |
| UY26475A1 (es) | 2001-01-31 |
| CN1607201A (zh) | 2005-04-20 |
| JP2003516378A (ja) | 2003-05-13 |
| HUP0203812A2 (hu) | 2003-03-28 |
| AU1808401A (en) | 2001-06-18 |
| MXPA02004829A (es) | 2003-10-14 |
| AR032433A1 (es) | 2003-11-12 |
| CO5280085A1 (es) | 2003-05-30 |
| BR0016201A (pt) | 2002-08-13 |
| EP1237847A1 (en) | 2002-09-11 |
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