DK1211250T3 - C10-Taxanderivater samt farmaceutiske præparater - Google Patents

C10-Taxanderivater samt farmaceutiske præparater

Info

Publication number
DK1211250T3
DK1211250T3 DK02005075T DK02005075T DK1211250T3 DK 1211250 T3 DK1211250 T3 DK 1211250T3 DK 02005075 T DK02005075 T DK 02005075T DK 02005075 T DK02005075 T DK 02005075T DK 1211250 T3 DK1211250 T3 DK 1211250T3
Authority
DK
Denmark
Prior art keywords
well
pharmaceutical preparations
taxane derivatives
taxane
derivatives
Prior art date
Application number
DK02005075T
Other languages
English (en)
Inventor
Robert A Holton
Ki-Byung Chai
Original Assignee
Univ Florida State
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/005,229 external-priority patent/US5338872A/en
Application filed by Univ Florida State filed Critical Univ Florida State
Application granted granted Critical
Publication of DK1211250T3 publication Critical patent/DK1211250T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D305/00Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D407/00Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • C07F7/18Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804Compounds having Si-O-C linkages

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
DK02005075T 1993-01-15 1994-01-14 C10-Taxanderivater samt farmaceutiske præparater DK1211250T3 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US08/005,229 US5338872A (en) 1993-01-15 1993-01-15 Process for the preparation of 10-desacetoxybaccatin III and 10-desacetoxytaxol and derivatives thereof
US3485293A 1993-03-22 1993-03-22
US9454593A 1993-07-20 1993-07-20
EP94909453A EP0679082B1 (en) 1993-01-15 1994-01-14 C10 taxane derivatives and pharmaceutical compositions

Publications (1)

Publication Number Publication Date
DK1211250T3 true DK1211250T3 (da) 2004-10-25

Family

ID=27357839

Family Applications (2)

Application Number Title Priority Date Filing Date
DK94909453T DK0679082T3 (da) 1993-01-15 1994-01-14 C10-Taxanderivater og farmaceutiske præparater
DK02005075T DK1211250T3 (da) 1993-01-15 1994-01-14 C10-Taxanderivater samt farmaceutiske præparater

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK94909453T DK0679082T3 (da) 1993-01-15 1994-01-14 C10-Taxanderivater og farmaceutiske præparater

Country Status (12)

Country Link
EP (2) EP1211250B1 (da)
JP (1) JP3917173B2 (da)
CN (2) CN1244569C (da)
AT (2) ATE269315T1 (da)
AU (1) AU682852B2 (da)
CA (1) CA2153805C (da)
DE (2) DE69433856T2 (da)
DK (2) DK0679082T3 (da)
ES (2) ES2184761T3 (da)
IL (1) IL108316A (da)
PT (2) PT1211250E (da)
WO (1) WO1994015599A1 (da)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5710287A (en) 1991-09-23 1998-01-20 Florida State University Taxanes having an amino substituted side-chain and pharmaceutical compositions containing them
US5440056A (en) * 1992-04-17 1995-08-08 Abbott Laboratories 9-deoxotaxane compounds
AU682173B2 (en) * 1993-01-15 1997-09-25 Florida State University Process for the preparation of 10-desacetoxybaccatin III
IL108443A0 (en) * 1993-01-29 1994-04-12 Univ Florida State C7 taxane derivatives and pharmaceutical compositions containing them
US5677470A (en) * 1994-06-28 1997-10-14 Tanabe Seiyaku Co., Ltd. Baccatin derivatives and processes for preparing the same
CA2162759A1 (en) * 1994-11-17 1996-05-18 Kenji Tsujihara Baccatin derivatives and processes for preparing the same
JP4192208B2 (ja) * 1995-09-12 2008-12-10 セファロン リミテッド 加水分解促進性のタキサン疎水性誘導体
US5773464A (en) * 1996-09-30 1998-06-30 Bristol-Myers Squibb Company C-10 epoxy taxanes
DE60131537T2 (de) 2000-06-22 2008-10-23 Nitromed, Inc., Lexington Nitrosierte und nitrosylierte taxane, zubereitungen und methoden der verwendung
US8785669B2 (en) * 2010-06-30 2014-07-22 Gfv, Llc Taxane compounds, compositions and methods

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4960790A (en) * 1989-03-09 1990-10-02 University Of Kansas Derivatives of taxol, pharmaceutical compositions thereof and methods for the preparation thereof
US5175315A (en) * 1989-05-31 1992-12-29 Florida State University Method for preparation of taxol using β-lactam
US5243045A (en) * 1991-09-23 1993-09-07 Florida State University Certain alkoxy substituted taxanes and pharmaceutical compositions containing them
US5250683A (en) * 1991-09-23 1993-10-05 Florida State University Certain substituted taxanes and pharmaceutical compositions containing them
US5200534A (en) * 1992-03-13 1993-04-06 University Of Florida Process for the preparation of taxol and 10-deacetyltaxol
US5248796A (en) * 1992-06-18 1993-09-28 Bristol-Myers Squibb Company Taxol derivatives
CA2109861C (en) * 1992-12-04 1999-03-16 Shu-Hui Chen 6,7-modified paclitaxels
FR2707293A1 (fr) * 1993-07-08 1995-01-13 Rhone Poulenc Rorer Sa Nouveaux taxoides, leur préparation et les compositions pharmaceutiques qui les contiennent.

Also Published As

Publication number Publication date
EP0679082A1 (en) 1995-11-02
CN1125060C (zh) 2003-10-22
IL108316A0 (en) 1994-04-12
DE69431514D1 (de) 2002-11-14
DK0679082T3 (da) 2003-02-17
CN1495177A (zh) 2004-05-12
EP0679082A4 (en) 1995-12-20
AU682852B2 (en) 1997-10-23
DE69433856T2 (de) 2004-11-04
JP3917173B2 (ja) 2007-05-23
CN1244569C (zh) 2006-03-08
EP0679082B1 (en) 2002-10-09
WO1994015599A1 (en) 1994-07-21
CA2153805C (en) 2006-03-28
EP1211250A1 (en) 2002-06-05
ATE225656T1 (de) 2002-10-15
CA2153805A1 (en) 1994-07-21
PT679082E (pt) 2003-02-28
JPH08505627A (ja) 1996-06-18
PT1211250E (pt) 2004-10-29
AU6229594A (en) 1994-08-15
CN1097746A (zh) 1995-01-25
ES2184761T3 (es) 2003-04-16
EP1211250B1 (en) 2004-06-16
ES2225671T3 (es) 2005-03-16
ATE269315T1 (de) 2004-07-15
DE69433856D1 (de) 2004-07-22
IL108316A (en) 2006-10-31
DE69431514T2 (de) 2003-02-13

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