DK1185267T3 - Dermale bedövelsesmidler - Google Patents
Dermale bedövelsesmidlerInfo
- Publication number
- DK1185267T3 DK1185267T3 DK00941227T DK00941227T DK1185267T3 DK 1185267 T3 DK1185267 T3 DK 1185267T3 DK 00941227 T DK00941227 T DK 00941227T DK 00941227 T DK00941227 T DK 00941227T DK 1185267 T3 DK1185267 T3 DK 1185267T3
- Authority
- DK
- Denmark
- Prior art keywords
- compounds
- anesthetics
- dermal
- aminoindane
- dermal anesthetics
- Prior art date
Links
- 230000002500 effect on skin Effects 0.000 title abstract 2
- 229940035674 anesthetics Drugs 0.000 title 1
- 239000003193 general anesthetic agent Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 239000003589 local anesthetic agent Substances 0.000 abstract 2
- XJEVHMGJSYVQBQ-UHFFFAOYSA-N 2,3-dihydro-1h-inden-1-amine Chemical class C1=CC=C2C(N)CCC2=C1 XJEVHMGJSYVQBQ-UHFFFAOYSA-N 0.000 abstract 1
- DEEUGGDCCPTQEN-UHFFFAOYSA-N C1CCNCC1.C1=CC=C2C(N)CCC2=C1 Chemical class C1CCNCC1.C1=CC=C2C(N)CCC2=C1 DEEUGGDCCPTQEN-UHFFFAOYSA-N 0.000 abstract 1
- 241000124008 Mammalia Species 0.000 abstract 1
- 229960005015 local anesthetics Drugs 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/34—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/136—Amines having aromatic rings, e.g. ketamine, nortriptyline having the amino group directly attached to the aromatic ring, e.g. benzeneamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
- A61P23/02—Local anaesthetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/26—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Anesthesiology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13835399P | 1999-06-10 | 1999-06-10 | |
| US17926700P | 2000-01-31 | 2000-01-31 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1185267T3 true DK1185267T3 (da) | 2006-12-11 |
Family
ID=26836123
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK00941227T DK1185267T3 (da) | 1999-06-10 | 2000-06-06 | Dermale bedövelsesmidler |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US6413987B1 (https=) |
| EP (1) | EP1185267B1 (https=) |
| JP (1) | JP2003501469A (https=) |
| CN (1) | CN1355700A (https=) |
| AT (1) | ATE335482T1 (https=) |
| AU (1) | AU777517B2 (https=) |
| BR (1) | BR0011028A (https=) |
| CA (1) | CA2376819C (https=) |
| CY (1) | CY1105721T1 (https=) |
| DE (1) | DE60029954T2 (https=) |
| DK (1) | DK1185267T3 (https=) |
| ES (1) | ES2267546T3 (https=) |
| IL (2) | IL146190A0 (https=) |
| MX (1) | MXPA01012632A (https=) |
| NO (1) | NO323856B1 (https=) |
| NZ (1) | NZ515143A (https=) |
| PT (1) | PT1185267E (https=) |
| WO (1) | WO2000076510A1 (https=) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE60122541T2 (de) * | 2001-12-21 | 2007-09-13 | Chiesi Farmaceutici S.P.A. | 2-Indanylaminoderivate zur Therapie von chronischen, akuten oder entzündlichen Schmerzen |
| EP1566378B1 (en) * | 2002-11-26 | 2012-08-15 | Maruishi Pharmaceutical Co., Ltd. | Isoindoline derivative |
| US20060079558A1 (en) * | 2004-09-27 | 2006-04-13 | Bridge Pharma. Inc. | R-isomer of 2-{2[N-(2-indanyl)-N-phenylamino]ethyl}piperidine and other dermal anesthetics |
| WO2006036936A2 (en) * | 2004-09-27 | 2006-04-06 | Bridge Pharma, Inc. | The s-isomer of 2-{2-[n-(2-indanyl)-n-phenylamino]ethyl}piperidine and other dermal anesthetic agents |
| US20090137628A1 (en) * | 2005-09-23 | 2009-05-28 | Bridge Pharma, Inc. | Formulations of Indanylamines and the Use Thereof as Local Anesthetics and as Medication for Chronic Pain |
| US20110218218A1 (en) * | 2005-09-23 | 2011-09-08 | Bridge Pharma, Inc. | Formulations Of Indanylamines And The Use Thereof As Local Anesthetics And As Medication For Chronic Pain |
| US7592458B2 (en) * | 2006-07-21 | 2009-09-22 | Wright George E | Dermal anesthetic compounds and pharmaceutical compositions for inducing local anesthesia and mitigating neuropathic pain |
| EP3581169A1 (en) * | 2008-01-22 | 2019-12-18 | The Board Of Regents Of The University Of Texas System | Volatile anesthetic compositions comprising extractive solvents for regional anesthesia and/or pain relief |
| UA112769C2 (uk) * | 2011-02-18 | 2016-10-25 | Ендо Фармасьютікалз Інк. | Аміноінданові сполуки і їх застосування при лікуванні болю |
| US8809372B2 (en) | 2011-09-30 | 2014-08-19 | Asana Biosciences, Llc | Pyridine derivatives |
| HUE032240T2 (en) | 2011-10-24 | 2017-09-28 | Asana Biosciences Llc | cyclohexylamines |
| WO2014028675A1 (en) | 2012-08-15 | 2014-02-20 | Endo Pharmaceuticals Inc. | Use of aminoindane compounds in treating overactive bladder and interstitial cystitis |
| JP7145363B2 (ja) | 2015-11-23 | 2022-10-03 | グレイス セラピューティクス インコーポレイテッド | 局所皮膜形成スプレー |
| CN113573705A (zh) | 2018-12-19 | 2021-10-29 | 诺迪克控股公司 | 鼻内利多卡因的治疗组合物 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE760018A (fr) * | 1969-12-19 | 1971-06-08 | Christiaens Sa A | Nouveau derives du 2-amino-indane, leur preparation et leur utilisation |
| US3923813A (en) | 1969-12-19 | 1975-12-02 | Christiaens Sa A | Derivatives of 2-aminoindanes |
| AR206505A1 (es) * | 1972-09-18 | 1976-07-30 | Christiaens Sa A | Procedimiento para obtener nuevos derivados de n-fenil-n-aminoalquil-2-aminoindano |
| ZA738419B (en) | 1972-11-06 | 1974-09-25 | Christiaens Sa A | New derivatives of 2-aminoindane,the preparation and use thereof |
| GB1462036A (en) * | 1973-02-05 | 1977-01-19 | Manuf Prod Pharma | Aminoindane derivatives |
| GB1468347A (en) * | 1973-03-02 | 1977-03-23 | Christiaens Sa A | Aminoindanes |
-
2000
- 2000-06-06 AU AU55963/00A patent/AU777517B2/en not_active Ceased
- 2000-06-06 CA CA002376819A patent/CA2376819C/en not_active Expired - Fee Related
- 2000-06-06 CN CN00808753A patent/CN1355700A/zh active Pending
- 2000-06-06 IL IL14619000A patent/IL146190A0/xx unknown
- 2000-06-06 JP JP2001502843A patent/JP2003501469A/ja active Pending
- 2000-06-06 EP EP00941227A patent/EP1185267B1/en not_active Expired - Lifetime
- 2000-06-06 BR BR0011028-0A patent/BR0011028A/pt not_active Application Discontinuation
- 2000-06-06 US US09/588,582 patent/US6413987B1/en not_active Expired - Fee Related
- 2000-06-06 NZ NZ515143A patent/NZ515143A/en not_active IP Right Cessation
- 2000-06-06 PT PT00941227T patent/PT1185267E/pt unknown
- 2000-06-06 AT AT00941227T patent/ATE335482T1/de not_active IP Right Cessation
- 2000-06-06 DK DK00941227T patent/DK1185267T3/da active
- 2000-06-06 WO PCT/US2000/015490 patent/WO2000076510A1/en not_active Ceased
- 2000-06-06 DE DE60029954T patent/DE60029954T2/de not_active Expired - Fee Related
- 2000-06-06 ES ES00941227T patent/ES2267546T3/es not_active Expired - Lifetime
- 2000-06-06 MX MXPA01012632A patent/MXPA01012632A/es active IP Right Grant
-
2001
- 2001-10-25 IL IL146190A patent/IL146190A/en not_active IP Right Cessation
- 2001-12-10 NO NO20016037A patent/NO323856B1/no unknown
-
2006
- 2006-10-23 CY CY20061101516T patent/CY1105721T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PT1185267E (pt) | 2006-12-29 |
| NO20016037D0 (no) | 2001-12-10 |
| EP1185267B1 (en) | 2006-08-09 |
| EP1185267A1 (en) | 2002-03-13 |
| IL146190A0 (en) | 2002-07-25 |
| WO2000076510A1 (en) | 2000-12-21 |
| JP2003501469A (ja) | 2003-01-14 |
| US6413987B1 (en) | 2002-07-02 |
| AU777517B2 (en) | 2004-10-21 |
| NO20016037L (no) | 2002-02-11 |
| ES2267546T3 (es) | 2007-03-16 |
| CA2376819C (en) | 2008-09-02 |
| IL146190A (en) | 2008-11-03 |
| CN1355700A (zh) | 2002-06-26 |
| NO323856B1 (no) | 2007-07-16 |
| DE60029954D1 (de) | 2006-09-21 |
| CA2376819A1 (en) | 2000-12-21 |
| DE60029954T2 (de) | 2007-03-08 |
| WO2000076510A9 (en) | 2002-07-04 |
| EP1185267A4 (en) | 2003-09-03 |
| BR0011028A (pt) | 2002-02-19 |
| NZ515143A (en) | 2004-05-28 |
| ATE335482T1 (de) | 2006-09-15 |
| AU5596300A (en) | 2001-01-02 |
| CY1105721T1 (el) | 2010-12-22 |
| MXPA01012632A (es) | 2004-03-19 |
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