DK118482A - Fremgangsmaade til fremstilling af 2,4,5-trisubstituerede thiazoler eller salte deraf - Google Patents
Fremgangsmaade til fremstilling af 2,4,5-trisubstituerede thiazoler eller salte deraf Download PDFInfo
- Publication number
- DK118482A DK118482A DK118482A DK118482A DK118482A DK 118482 A DK118482 A DK 118482A DK 118482 A DK118482 A DK 118482A DK 118482 A DK118482 A DK 118482A DK 118482 A DK118482 A DK 118482A
- Authority
- DK
- Denmark
- Prior art keywords
- thiazols
- trisubstituted
- salts
- procedure
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
- C07D213/46—Oxygen atoms
- C07D213/50—Ketonic radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D277/24—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D277/30—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/36—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pain & Pain Management (AREA)
- Pharmacology & Pharmacy (AREA)
- Rheumatology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH183881 | 1981-03-18 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK118482A true DK118482A (da) | 1982-09-19 |
Family
ID=4219779
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK118482A DK118482A (da) | 1981-03-18 | 1982-03-17 | Fremgangsmaade til fremstilling af 2,4,5-trisubstituerede thiazoler eller salte deraf |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US4451471A (fi) |
| EP (1) | EP0061425A3 (fi) |
| JP (1) | JPS57183767A (fi) |
| KR (1) | KR830009066A (fi) |
| AU (1) | AU8166782A (fi) |
| DK (1) | DK118482A (fi) |
| ES (8) | ES510504A0 (fi) |
| FI (1) | FI820877L (fi) |
| GB (1) | GB2098203B (fi) |
| GR (1) | GR78347B (fi) |
| HU (1) | HU187684B (fi) |
| IL (1) | IL65285A (fi) |
| NO (1) | NO820881L (fi) |
| NZ (1) | NZ200038A (fi) |
| PT (1) | PT74593B (fi) |
| ZA (1) | ZA821790B (fi) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4632930A (en) * | 1984-11-30 | 1986-12-30 | E. I. Du Pont De Nemours And Company | Antihypertensive alkyl-arylimidazole, thiazole and oxazole derivatives |
| DE3508666A1 (de) * | 1985-03-12 | 1986-09-18 | Hoechst Ag, 6230 Frankfurt | Heterocyclische disulfide und ihre anwendung als immunmodulatoren |
| DE3508665A1 (de) * | 1985-03-12 | 1986-09-18 | Hoechst Ag, 6230 Frankfurt | Heterocyclische sulfide und ihre anwendung als immunmodulatoren |
| JPS6339868A (ja) * | 1986-08-04 | 1988-02-20 | Otsuka Pharmaceut Factory Inc | ジ低級アルキルフエノ−ル誘導体 |
| ES2038279T3 (es) * | 1987-07-27 | 1993-07-16 | Duphar International Research B.V | Metodo para preparar compuestos de tiazol. |
| AT392788B (de) * | 1988-02-03 | 1991-06-10 | Fisons Plc | Neue benzimidazolverbindungen, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische zubereitungen |
| DE3807232A1 (de) * | 1988-03-05 | 1989-09-14 | Bayer Ag | Substituierte acrylsaeureester |
| JP2933739B2 (ja) * | 1990-04-09 | 1999-08-16 | 明治製菓株式会社 | チアゾールまたはイミダゾール誘導体および抗潰瘍剤 |
| US5255697A (en) * | 1991-10-23 | 1993-10-26 | Working Inc. | Walking support apparatus |
| JP2636819B2 (ja) | 1994-12-20 | 1997-07-30 | 日本たばこ産業株式会社 | オキサゾール系複素環式芳香族化合物 |
| CA2381215A1 (en) | 1999-08-06 | 2001-02-15 | Takeda Chemical Industries, Ltd. | P38map kinase inhibitors |
| BRPI0706621A2 (pt) * | 2006-01-18 | 2011-04-05 | Amgen Inc | composto, composição farmacêutica, métodos para tratar um distúrbio mediado por quinase em um mamìfero e para tratar um distúrbio relacionado com a proliferação em um mamìfero, e , uso do composto |
| WO2009011871A2 (en) * | 2007-07-17 | 2009-01-22 | Amgen Inc. | Thiadiazole modulators of pkb |
| EP2872509B1 (en) | 2012-07-12 | 2016-09-14 | Chiesi Farmaceutici S.p.A. | Inhibition of enzymes |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2129012A1 (de) * | 1971-06-11 | 1973-01-04 | Merck Patent Gmbh | Azol-derivate |
| FR2146161A1 (en) * | 1971-07-22 | 1973-03-02 | Roussel Uclaf | Thiazolyl thiolacetic acids - analgesics antiinflammatories and antipyretics |
| US3888870A (en) * | 1974-03-08 | 1975-06-10 | Sandoz Ag | 2-sulfinyl-thiazoles and oxazoles |
| US4022607A (en) * | 1975-06-09 | 1977-05-10 | Sandoz, Inc. | Substituted oxazoles and thiazoles as herbicides |
-
1982
- 1982-03-08 US US06/355,989 patent/US4451471A/en not_active Expired - Fee Related
- 1982-03-12 EP EP82810111A patent/EP0061425A3/de not_active Withdrawn
- 1982-03-15 FI FI820877A patent/FI820877L/fi not_active Application Discontinuation
- 1982-03-17 NZ NZ200038A patent/NZ200038A/en unknown
- 1982-03-17 ES ES510504A patent/ES510504A0/es active Granted
- 1982-03-17 GB GB8207759A patent/GB2098203B/en not_active Expired
- 1982-03-17 NO NO820881A patent/NO820881L/no unknown
- 1982-03-17 DK DK118482A patent/DK118482A/da not_active Application Discontinuation
- 1982-03-17 HU HU82811A patent/HU187684B/hu unknown
- 1982-03-17 PT PT74593A patent/PT74593B/pt unknown
- 1982-03-17 ZA ZA821790A patent/ZA821790B/xx unknown
- 1982-03-18 JP JP57041809A patent/JPS57183767A/ja active Pending
- 1982-03-18 KR KR1019820001200A patent/KR830009066A/ko unknown
- 1982-03-18 IL IL65285A patent/IL65285A/xx unknown
- 1982-03-18 AU AU81667/82A patent/AU8166782A/en not_active Abandoned
-
1983
- 1983-05-30 GR GR67611A patent/GR78347B/el unknown
- 1983-05-31 ES ES522868A patent/ES8502980A1/es not_active Expired
- 1983-05-31 ES ES522869A patent/ES522869A0/es active Granted
- 1983-05-31 ES ES522867A patent/ES522867A0/es active Granted
-
1984
- 1984-10-31 ES ES537278A patent/ES8603499A1/es not_active Expired
- 1984-10-31 ES ES537277A patent/ES8603847A1/es not_active Expired
- 1984-11-02 ES ES537342A patent/ES8604180A1/es not_active Expired
- 1984-11-02 ES ES537343A patent/ES537343A0/es active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| ES8601171A1 (es) | 1985-10-16 |
| FI820877L (fi) | 1982-09-19 |
| ES8400102A1 (es) | 1983-10-16 |
| GB2098203B (en) | 1985-05-09 |
| ES537277A0 (es) | 1986-01-01 |
| PT74593B (de) | 1984-11-27 |
| IL65285A0 (en) | 1982-05-31 |
| ES522868A0 (es) | 1985-02-01 |
| ES537343A0 (es) | 1985-10-16 |
| ES8603498A1 (es) | 1985-12-16 |
| EP0061425A2 (de) | 1982-09-29 |
| ES537342A0 (es) | 1986-01-16 |
| ES8603847A1 (es) | 1986-01-01 |
| ES8503677A1 (es) | 1985-03-16 |
| EP0061425A3 (de) | 1982-12-15 |
| JPS57183767A (en) | 1982-11-12 |
| ES537278A0 (es) | 1985-12-16 |
| ES522867A0 (es) | 1985-12-16 |
| ZA821790B (en) | 1983-01-26 |
| ES8502980A1 (es) | 1985-02-01 |
| ES8604180A1 (es) | 1986-01-16 |
| ES510504A0 (es) | 1983-10-16 |
| ES8603499A1 (es) | 1985-12-16 |
| NZ200038A (en) | 1985-05-31 |
| IL65285A (en) | 1985-11-29 |
| ES522869A0 (es) | 1985-03-16 |
| GR78347B (fi) | 1984-09-26 |
| US4451471A (en) | 1984-05-29 |
| HU187684B (en) | 1986-02-28 |
| PT74593A (de) | 1982-04-01 |
| GB2098203A (en) | 1982-11-17 |
| NO820881L (no) | 1982-09-20 |
| AU8166782A (en) | 1982-09-23 |
| KR830009066A (ko) | 1983-12-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AHB | Application shelved due to non-payment | ||
| AHB | Application shelved due to non-payment |