DK1179005T3 - Steroidforbindelser med en C17-alkyl-sidekæde og en aromatisk A-ring til anvendelse i terapi - Google Patents
Steroidforbindelser med en C17-alkyl-sidekæde og en aromatisk A-ring til anvendelse i terapiInfo
- Publication number
- DK1179005T3 DK1179005T3 DK00927569T DK00927569T DK1179005T3 DK 1179005 T3 DK1179005 T3 DK 1179005T3 DK 00927569 T DK00927569 T DK 00927569T DK 00927569 T DK00927569 T DK 00927569T DK 1179005 T3 DK1179005 T3 DK 1179005T3
- Authority
- DK
- Denmark
- Prior art keywords
- sup
- group
- hydrogen atom
- hydroxyl
- therapy
- Prior art date
Links
- 125000003118 aryl group Chemical group 0.000 title abstract 2
- -1 Steroid compounds Chemical class 0.000 title 1
- 238000002560 therapeutic procedure Methods 0.000 title 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 4
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 4
- 125000001931 aliphatic group Chemical group 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000004450 alkenylene group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 125000000304 alkynyl group Chemical group 0.000 abstract 1
- 125000004419 alkynylene group Chemical group 0.000 abstract 1
- 230000000125 calcaemic effect Effects 0.000 abstract 1
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 abstract 1
- 230000024245 cell differentiation Effects 0.000 abstract 1
- 230000010261 cell growth Effects 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 230000003389 potentiating effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0072—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the A ring of the steroid being aromatic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/18—Drugs for disorders of the endocrine system of the parathyroid hormones
- A61P5/20—Drugs for disorders of the endocrine system of the parathyroid hormones for decreasing, blocking or antagonising the activity of PTH
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Physical Education & Sports Medicine (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Neurology (AREA)
- Rheumatology (AREA)
- Neurosurgery (AREA)
- Dermatology (AREA)
- Pulmonology (AREA)
- Heart & Thoracic Surgery (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Cardiology (AREA)
- Gynecology & Obstetrics (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Urology & Nephrology (AREA)
- Obesity (AREA)
- Vascular Medicine (AREA)
- Pregnancy & Childbirth (AREA)
- Transplantation (AREA)
- Pain & Pain Management (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9910934.0A GB9910934D0 (en) | 1999-05-11 | 1999-05-11 | Chemical compounds |
| PCT/GB2000/001813 WO2000068246A1 (en) | 1999-05-11 | 2000-05-11 | Steroid compounds with a c17-alkyl side chain and an aromatic a-ring for use in therapy |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1179005T3 true DK1179005T3 (da) | 2004-03-01 |
Family
ID=10853250
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK00927569T DK1179005T3 (da) | 1999-05-11 | 2000-05-11 | Steroidforbindelser med en C17-alkyl-sidekæde og en aromatisk A-ring til anvendelse i terapi |
Country Status (21)
| Country | Link |
|---|---|
| US (2) | US6881730B1 (cs) |
| EP (1) | EP1179005B1 (cs) |
| JP (1) | JP2002544137A (cs) |
| KR (1) | KR100690040B1 (cs) |
| CN (1) | CN1158297C (cs) |
| AT (1) | ATE254629T1 (cs) |
| AU (1) | AU779743B2 (cs) |
| CA (1) | CA2373443A1 (cs) |
| CZ (1) | CZ297316B6 (cs) |
| DE (1) | DE60006665T2 (cs) |
| DK (1) | DK1179005T3 (cs) |
| ES (1) | ES2207509T3 (cs) |
| GB (1) | GB9910934D0 (cs) |
| HK (1) | HK1046001B (cs) |
| HU (1) | HUP0201047A3 (cs) |
| IL (2) | IL146442A0 (cs) |
| NO (1) | NO319949B1 (cs) |
| NZ (1) | NZ515482A (cs) |
| PT (1) | PT1179005E (cs) |
| WO (1) | WO2000068246A1 (cs) |
| ZA (1) | ZA200109272B (cs) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6908910B2 (en) | 1993-08-06 | 2005-06-21 | The Children's Medical Center Corporation | Estrogenic compounds as anti-mitotic agents |
| GB9910934D0 (en) * | 1999-05-11 | 1999-07-14 | Res Inst Medicine Chem | Chemical compounds |
| US7087592B1 (en) | 1999-08-23 | 2006-08-08 | Entre Med, Inc. | Compositions comprising purified 2-methoxyestradiol and methods of producing same |
| IL152728A0 (en) * | 2000-05-11 | 2003-06-24 | Res Inst Medicine Chem | 2-substituted pregna-1,3,5 (10)-triene and chola-1,3,5(10)-triene derivatives and their biological activity |
| US6995278B2 (en) | 2000-08-18 | 2006-02-07 | Entre Med, Inc. | Antiangiogenic agents |
| US7135581B2 (en) | 2000-08-18 | 2006-11-14 | Entremed, Inc. | Antiangiogenic agents |
| WO2002042319A2 (en) * | 2000-11-27 | 2002-05-30 | Entremed, Inc. | 2-substituted estrogens as antiangiogenic agents |
| WO2002092100A1 (en) * | 2001-05-11 | 2002-11-21 | Marsden, John, Christopher | 17-(c(ch3) (ch2) o-3c (r4, r5) n (r6, r7))-substituted 19-nor-pregna-1, 3, 5(10)-triene derivatives and their medical use |
| CA2527074A1 (en) | 2003-05-28 | 2005-04-07 | Entremed, Inc. | Antiangiogenic agents |
| US7498322B2 (en) | 2004-03-12 | 2009-03-03 | Entremed, Inc. | Antiangiogenic agents |
| WO2007109312A2 (en) | 2006-03-20 | 2007-09-27 | Entremed, Inc. | Disease modifying anti-arthritic activity of 2-methoxyestradiol |
| CA2690841C (en) * | 2007-06-19 | 2012-11-27 | Kythera Biopharmaceuticals, Inc. | Synthetic bile acid composition, method, and preparation |
| US8242294B2 (en) | 2007-06-19 | 2012-08-14 | Kythera Biopharmaceuticals, Inc. | Synthetic bile acid compositions and methods |
| US20080318870A1 (en) | 2007-06-19 | 2008-12-25 | Kythera Biopharmaceuticals, Inc. | Synthetic bile acid compositions and methods |
| JOP20180077A1 (ar) | 2007-06-19 | 2019-01-30 | Kythera Biopharmaceuticals Inc | تركيبات وطرق لحمض صفراوي تخليقي |
| HRP20230747T1 (hr) | 2011-09-08 | 2024-01-05 | Sage Therapeutics, Inc. | Neuroaktivni steroidi, pripravci i njihova uporaba |
| SI2968369T1 (sl) | 2013-03-13 | 2019-01-31 | Sage Therapeutics, Inc. | Nevroaktivni steroidi in metode njihove uporabe |
| EP3157528B1 (en) | 2014-06-18 | 2023-09-13 | Sage Therapeutics, Inc. | Oxysterols and methods of use thereof |
| CA2991311A1 (en) | 2015-07-06 | 2017-01-12 | Sage Therapeutics, Inc. | Oxysterols and methods of use thereof |
| PH12021551134A1 (en) | 2015-07-06 | 2024-03-25 | Sage Therapeutics Inc | Oxysterols and methods of use thereof |
| EP4599887A3 (en) | 2015-07-06 | 2025-10-15 | Sage Therapeutics, Inc. | Oxysterols and methods of use thereof |
| CA3019146C (en) | 2016-04-01 | 2024-03-26 | Sage Therapeutics, Inc. | Oxysterols and methods of use thereof |
| WO2017193046A1 (en) | 2016-05-06 | 2017-11-09 | Sage Therapeutics, Inc. | Oxysterols and methods of use thereof |
| LT3481846T (lt) | 2016-07-07 | 2021-08-25 | Sage Therapeutics, Inc. | 11-pakeistieji 24-hidroksisteroliai, skirti naudoti gydant su nmda susijusias būkles |
| BR112019006365A2 (pt) | 2016-09-30 | 2019-08-06 | Sage Therapeutics Inc | oxisteróis substituídos c7 e métodos de utilização dos mesmos |
| AU2017345399B2 (en) | 2016-10-18 | 2022-02-24 | Sage Therapeutics, Inc. | Oxysterols and methods of use thereof |
| AU2017345400B2 (en) | 2016-10-18 | 2022-02-24 | Sage Therapeutics, Inc. | Oxysterols and methods of use thereof |
| CN115040524A (zh) * | 2022-07-27 | 2022-09-13 | 深圳市中西医结合医院 | 4-胆甾烯-3-酮用于治疗多发性骨髓瘤骨病的应用 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3562260A (en) * | 1965-08-23 | 1971-02-09 | Ormonoterapia Richter Spa | 2-carbonyl-estratrienes and method of their preparation |
| GB1267915A (en) * | 1968-05-24 | 1972-03-22 | Glaxo Lab Ltd | Ring a-substituted ring a-aromatic steroids |
| FR2528434B1 (fr) * | 1982-06-11 | 1985-07-19 | Roussel Uclaf | Nouveaux 19-nor steroides substitues en 11b et eventuellement en 2, leur procede de preparation et leur application comme medicament |
| JP2623285B2 (ja) * | 1988-03-09 | 1997-06-25 | 雪印乳業株式会社 | ２（３―ハイドロキシ―１，３，５（１０）―エストリエン―１７―イル）プロピオン酸の製造法 |
| GB9910934D0 (en) * | 1999-05-11 | 1999-07-14 | Res Inst Medicine Chem | Chemical compounds |
| US6967195B2 (en) * | 2000-05-11 | 2005-11-22 | Research Institute For Medicine And Chemistry, Inc. | 2-substituted pregna-1-3,5(10) triene and chola-1,3,5(10) triene derivatives and their biological activity |
-
1999
- 1999-05-11 GB GBGB9910934.0A patent/GB9910934D0/en not_active Ceased
-
2000
- 2000-05-11 AU AU45960/00A patent/AU779743B2/en not_active Ceased
- 2000-05-11 KR KR1020017014382A patent/KR100690040B1/ko not_active Expired - Fee Related
- 2000-05-11 HK HK02105910.4A patent/HK1046001B/en not_active IP Right Cessation
- 2000-05-11 IL IL14644200A patent/IL146442A0/xx active IP Right Grant
- 2000-05-11 PT PT00927569T patent/PT1179005E/pt unknown
- 2000-05-11 CA CA002373443A patent/CA2373443A1/en not_active Abandoned
- 2000-05-11 NZ NZ515482A patent/NZ515482A/en unknown
- 2000-05-11 EP EP00927569A patent/EP1179005B1/en not_active Expired - Lifetime
- 2000-05-11 CZ CZ20014049A patent/CZ297316B6/cs not_active IP Right Cessation
- 2000-05-11 CN CNB008095175A patent/CN1158297C/zh not_active Expired - Fee Related
- 2000-05-11 DE DE60006665T patent/DE60006665T2/de not_active Expired - Fee Related
- 2000-05-11 WO PCT/GB2000/001813 patent/WO2000068246A1/en not_active Ceased
- 2000-05-11 HU HU0201047A patent/HUP0201047A3/hu unknown
- 2000-05-11 DK DK00927569T patent/DK1179005T3/da active
- 2000-05-11 AT AT00927569T patent/ATE254629T1/de not_active IP Right Cessation
- 2000-05-11 JP JP2000616220A patent/JP2002544137A/ja active Pending
- 2000-05-11 ES ES00927569T patent/ES2207509T3/es not_active Expired - Lifetime
-
2001
- 2001-11-09 ZA ZA200109272A patent/ZA200109272B/xx unknown
- 2001-11-11 IL IL146442A patent/IL146442A/en not_active IP Right Cessation
- 2001-11-12 NO NO20015520A patent/NO319949B1/no not_active IP Right Cessation
-
2003
- 2003-05-11 US US09/926,491 patent/US6881730B1/en not_active Expired - Fee Related
-
2005
- 2005-02-11 US US11/055,620 patent/US20050171075A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CA2373443A1 (en) | 2000-11-16 |
| NO319949B1 (no) | 2005-10-03 |
| ATE254629T1 (de) | 2003-12-15 |
| ES2207509T3 (es) | 2004-06-01 |
| EP1179005A1 (en) | 2002-02-13 |
| CZ20014049A3 (cs) | 2002-04-17 |
| PT1179005E (pt) | 2004-04-30 |
| HUP0201047A3 (en) | 2003-07-28 |
| HK1046001A1 (en) | 2002-12-20 |
| AU779743B2 (en) | 2005-02-10 |
| KR100690040B1 (ko) | 2007-03-09 |
| IL146442A0 (en) | 2002-07-25 |
| NO20015520L (no) | 2002-01-09 |
| AU4596000A (en) | 2000-11-21 |
| JP2002544137A (ja) | 2002-12-24 |
| US6881730B1 (en) | 2005-04-19 |
| CZ297316B6 (cs) | 2006-11-15 |
| KR20020013542A (ko) | 2002-02-20 |
| ZA200109272B (en) | 2003-02-26 |
| HUP0201047A2 (en) | 2002-08-28 |
| DE60006665D1 (de) | 2003-12-24 |
| DE60006665T2 (de) | 2004-10-07 |
| EP1179005B1 (en) | 2003-11-19 |
| WO2000068246A1 (en) | 2000-11-16 |
| GB9910934D0 (en) | 1999-07-14 |
| HK1046001B (en) | 2004-12-24 |
| CN1358193A (zh) | 2002-07-10 |
| IL146442A (en) | 2006-10-05 |
| CN1158297C (zh) | 2004-07-21 |
| US20050171075A1 (en) | 2005-08-04 |
| NZ515482A (en) | 2004-05-28 |
| NO20015520D0 (no) | 2001-11-12 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK1179005T3 (da) | Steroidforbindelser med en C17-alkyl-sidekæde og en aromatisk A-ring til anvendelse i terapi | |
| NZ505348A (en) | 11beta-halogen-7alpha-substituted estratriene derivatives | |
| BG101190A (en) | Pharmaceutical preparation containing estra-1,3,5/10/-triene derivatives | |
| NO308739B1 (no) | Imidazolderivater samt medisinsk sammensetning og anti-HIV- sammensetning omfattende samme | |
| CA2304713A1 (en) | Biphenyl-5-alkanoic acid derivatives and use thereof | |
| KR860005832A (ko) | 위치 10에 치환된 스테로이드의 제조방법 | |
| ES468119A1 (es) | Un procedimiento para la preparacion de triazinas | |
| RO82369B (ro) | Procedeu pentru prepararea unor derivati de 9-amino-dibenzopiran | |
| ATE411335T1 (de) | Östrogen-sulfamate als sulfataseinhibitoren | |
| GB8622330D0 (en) | 4-substituted 6-alkylidenandrostene-3,17-dione derivatives | |
| TR199801415T2 (xx) | Se�ici taksanlar,bunlar� haz�rlamak i�in y�ntem ve bunlar�n ila� olarak kullan�m�. | |
| NO20025392L (no) | 2-substituerte pregna-1,3-5(10)-trien og chola-1,3,5(10)- trienderivater ogderes biologiske aktivitet | |
| DE60216239T8 (de) | Verwendung von Cyclohexenon-Derivaten zur Herstellung eines Arzneimittels zur Behandlung von Dysurie | |
| CA2029509A1 (en) | Method for the Preparation of Methyl Ethers of Polyether Polyols Employing Dimethylsulfate as a Methylating Agent | |
| BE904983A (fr) | Acides propenylaminothiazolylcephalosporaniques 3-substitues et leurs esters. | |
| EP0385446A3 (en) | Osteogenesis promotion with use of vitamin d derivatives | |
| NZ231052A (en) | Substituted anthracyclinones and related glycosides | |
| DK0546547T3 (da) | Farmaceutisk præparat til forbedring af dysuri | |
| WO1990008529A3 (en) | 7-alkoxycoumarins, dihydropsoralens, and benzodipyranones as photo-activated therapeutic agents and inhibitors of epidermal growth factor | |
| DE69305684D1 (de) | Octahydronaphthalenoxim Derivate für die Inhibierung der Cholesterin Biosynthese, ihre Herstellung und Verwendung | |
| DE60026161D1 (de) | Amidin-derivate, ihre herstellung und verwendung als medikamenten | |
| MY102457A (en) | Isoquinoline derivatives | |
| TW345487B (en) | Composition for controlling noxious insects and/or mites comprising an ester compound | |
| ATE72443T1 (de) | Glucopyranose-derivate. | |
| EP0285142A3 (en) | 3-acylamino-3-deoxyallose derivatives |