DK1165834T3 - High-Throughput-Screening-fremgangsmåde til bestemmelse af enantioselektivitet - Google Patents
High-Throughput-Screening-fremgangsmåde til bestemmelse af enantioselektivitetInfo
- Publication number
- DK1165834T3 DK1165834T3 DK00909352T DK00909352T DK1165834T3 DK 1165834 T3 DK1165834 T3 DK 1165834T3 DK 00909352 T DK00909352 T DK 00909352T DK 00909352 T DK00909352 T DK 00909352T DK 1165834 T3 DK1165834 T3 DK 1165834T3
- Authority
- DK
- Denmark
- Prior art keywords
- throughput screening
- isotope
- enantioselectivity
- screening method
- biocatalysts
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 4
- 238000013537 high throughput screening Methods 0.000 title abstract 2
- 238000006243 chemical reaction Methods 0.000 abstract 2
- 102000004190 Enzymes Human genes 0.000 abstract 1
- 108090000790 Enzymes Proteins 0.000 abstract 1
- 239000013543 active substance Substances 0.000 abstract 1
- 239000011942 biocatalyst Substances 0.000 abstract 1
- 239000007795 chemical reaction product Substances 0.000 abstract 1
- 150000001875 compounds Chemical group 0.000 abstract 1
- 239000002638 heterogeneous catalyst Substances 0.000 abstract 1
- 239000002815 homogeneous catalyst Substances 0.000 abstract 1
- 238000011895 specific detection Methods 0.000 abstract 1
- 239000000758 substrate Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
- Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
- Analysing Materials By The Use Of Radiation (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Catalysts (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19913858A DE19913858A1 (de) | 1999-03-26 | 1999-03-26 | High-Throughput-Screening-Verfahren zur Bestimmung der Enantioselektivität asymmetrisch verlaufender Reaktionen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1165834T3 true DK1165834T3 (da) | 2005-01-24 |
Family
ID=7902585
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK00909352T DK1165834T3 (da) | 1999-03-26 | 2000-03-10 | High-Throughput-Screening-fremgangsmåde til bestemmelse af enantioselektivitet |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US6824982B1 (da) |
| EP (1) | EP1165834B1 (da) |
| JP (1) | JP2002540440A (da) |
| AT (1) | ATE276375T1 (da) |
| CA (1) | CA2368749A1 (da) |
| DE (2) | DE19913858A1 (da) |
| DK (1) | DK1165834T3 (da) |
| WO (1) | WO2000058504A1 (da) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7521216B2 (en) | 1999-12-29 | 2009-04-21 | Verenium Corporation | Nitrilases and methods for making and using them |
| US7300775B2 (en) | 1999-12-29 | 2007-11-27 | Verenium Corporation | Methods for producing α-substituted carboxylic acids using nitrilases and strecker reagents |
| US7608445B1 (en) | 1999-12-29 | 2009-10-27 | Verenium Corporation | Nitrilases, nucleic acids encoding them and methods for making and using them |
| DE10027794A1 (de) * | 2000-06-07 | 2001-12-13 | Basf Ag | Verfahren zur Analyse Enzym-katalysierter Umsetzungen mit MALDI-TOF-Massenspektrometrie |
| US20020127609A1 (en) * | 2001-02-23 | 2002-09-12 | Maxygen, Inc. | Screening for enzyme stereoselectivity utilizing mass spectrometry |
| DE10209177A1 (de) * | 2002-03-01 | 2003-09-18 | Studiengesellschaft Kohle Mbh | Ein Hoch-Durchsatz-Screening-Verfahren zur Bestimmung der Enantioselektivität von Katalysatoren, Biokatalysatoren und Agenzien |
| WO2003106415A2 (en) | 2002-06-13 | 2003-12-24 | Diversa Corporation | Processes for making (r)-ethyl 4-cyano-3-hydroxybutyric acid |
| US7335897B2 (en) * | 2004-03-30 | 2008-02-26 | Purdue Research Foundation | Method and system for desorption electrospray ionization |
| DK2115153T3 (da) | 2007-03-01 | 2013-09-08 | Bp Corp North America Inc | Nitrilaser, nucleinsyrer som koder for dem og fremgangsmåder til at fremstille og anvende disse |
| US9447135B2 (en) | 2012-12-14 | 2016-09-20 | University Of Kentucky Research Foundation | Semi-synthetic mithramycin derivatives with anti-cancer activity |
| US10024845B2 (en) | 2013-12-23 | 2018-07-17 | Basf Se | Methods for determining modulators of insect transient receptor potential V (TRPV) channel |
| CN111406065A (zh) | 2017-07-27 | 2020-07-10 | 南加利福尼亚大学 | 作为药物发现的靶标的耳蝶呤质子通道 |
| JP7376890B2 (ja) * | 2019-09-11 | 2023-11-09 | 大陽日酸株式会社 | 鏡像体過剰率の測定方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5629424A (en) * | 1995-11-29 | 1997-05-13 | The Curators Of The University Of Missouri | Stereoselective adsorptive bubble process |
| DE19731990A1 (de) * | 1997-07-25 | 1999-01-28 | Studiengesellschaft Kohle Mbh | Verfahren zur Herstellung und Identifizierung von neuen Hydrolasen mit verbesserten Eigenschaften |
| US6211370B1 (en) * | 1998-01-13 | 2001-04-03 | Harvard University | Asymmetric cycloaddition reactions |
-
1999
- 1999-03-26 DE DE19913858A patent/DE19913858A1/de not_active Withdrawn
-
2000
- 2000-03-10 AT AT00909352T patent/ATE276375T1/de not_active IP Right Cessation
- 2000-03-10 JP JP2000608782A patent/JP2002540440A/ja active Pending
- 2000-03-10 US US09/937,512 patent/US6824982B1/en not_active Expired - Fee Related
- 2000-03-10 DE DE50007782T patent/DE50007782D1/de not_active Expired - Fee Related
- 2000-03-10 EP EP00909352A patent/EP1165834B1/de not_active Expired - Lifetime
- 2000-03-10 CA CA002368749A patent/CA2368749A1/en not_active Abandoned
- 2000-03-10 DK DK00909352T patent/DK1165834T3/da active
- 2000-03-10 WO PCT/EP2000/002121 patent/WO2000058504A1/de not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| ATE276375T1 (de) | 2004-10-15 |
| EP1165834A1 (de) | 2002-01-02 |
| WO2000058504A1 (de) | 2000-10-05 |
| DE19913858A1 (de) | 2000-09-28 |
| CA2368749A1 (en) | 2000-10-05 |
| JP2002540440A (ja) | 2002-11-26 |
| EP1165834B1 (de) | 2004-09-15 |
| DE50007782D1 (de) | 2004-10-21 |
| US6824982B1 (en) | 2004-11-30 |
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