DK1151297T3 - Fremgangsmåde til forøgelse af bindingsinteraktioner mellem medlemmer af specifikke bindingspar - Google Patents
Fremgangsmåde til forøgelse af bindingsinteraktioner mellem medlemmer af specifikke bindingsparInfo
- Publication number
- DK1151297T3 DK1151297T3 DK00905755.5T DK00905755T DK1151297T3 DK 1151297 T3 DK1151297 T3 DK 1151297T3 DK 00905755 T DK00905755 T DK 00905755T DK 1151297 T3 DK1151297 T3 DK 1151297T3
- Authority
- DK
- Denmark
- Prior art keywords
- members
- binding
- reactions
- specific binding
- pairs
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
- G01N33/54326—Magnetic particles
- G01N33/54333—Modification of conditions of immunological binding reaction, e.g. use of more than one type of particle, use of chemical agents to improve binding, choice of incubation time or application of magnetic field during binding reaction
Landscapes
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- Pathology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Microbiology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Materials For Medical Uses (AREA)
- Reinforced Plastic Materials (AREA)
- Die Bonding (AREA)
- Joining Of Building Structures In Genera (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Sampling And Sample Adjustment (AREA)
- Pressure Welding/Diffusion-Bonding (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/240,939 US6551843B1 (en) | 1999-01-29 | 1999-01-29 | Methods for enhancing binding interactions between members of specific binding pairs |
PCT/US2000/002034 WO2000045169A1 (en) | 1999-01-29 | 2000-01-27 | Methods for enhancing binding interactions between members of specific binding pairs |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1151297T3 true DK1151297T3 (da) | 2010-03-01 |
Family
ID=22908555
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK00905755.5T DK1151297T3 (da) | 1999-01-29 | 2000-01-27 | Fremgangsmåde til forøgelse af bindingsinteraktioner mellem medlemmer af specifikke bindingspar |
Country Status (11)
Country | Link |
---|---|
US (1) | US6551843B1 (da) |
EP (1) | EP1151297B1 (da) |
JP (2) | JP2002535677A (da) |
AT (1) | ATE449333T1 (da) |
AU (1) | AU2738900A (da) |
CA (1) | CA2359664A1 (da) |
DE (1) | DE60043335D1 (da) |
DK (1) | DK1151297T3 (da) |
ES (1) | ES2335080T3 (da) |
PT (1) | PT1151297E (da) |
WO (1) | WO2000045169A1 (da) |
Families Citing this family (54)
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US7282350B2 (en) | 1998-02-12 | 2007-10-16 | Immunivest Corporation | Labeled cell sets for use as functional controls in rare cell detection assays |
US6623982B1 (en) * | 1999-07-12 | 2003-09-23 | Immunivest Corporation | Increased separation efficiency via controlled aggregation of magnetic nanoparticles |
JP4663957B2 (ja) * | 2000-07-14 | 2011-04-06 | ベリデックス・リミテッド・ライアビリティ・カンパニー | 磁性ナノ粒子の制御された凝集による増大した分離効率 |
US7863012B2 (en) * | 2004-02-17 | 2011-01-04 | Veridex, Llc | Analysis of circulating tumor cells, fragments, and debris |
US8980568B2 (en) * | 2001-10-11 | 2015-03-17 | Aviva Biosciences Corporation | Methods and compositions for detecting non-hematopoietic cells from a blood sample |
US8986944B2 (en) | 2001-10-11 | 2015-03-24 | Aviva Biosciences Corporation | Methods and compositions for separating rare cells from fluid samples |
US7764821B2 (en) | 2002-02-14 | 2010-07-27 | Veridex, Llc | Methods and algorithms for cell enumeration in a low-cost cytometer |
CA2474509C (en) | 2002-02-14 | 2012-01-31 | Immunivest Corporation | Methods and algorithms for cell enumeration in a low-cost cytometer |
JP4593557B2 (ja) | 2003-02-27 | 2010-12-08 | ベリデックス・リミテッド・ライアビリティ・カンパニー | 循環腫瘍細胞(ctc):転移癌患者における増悪までの時間、生存および療法に対する応答の早期評価 |
US20060035242A1 (en) | 2004-08-13 | 2006-02-16 | Michelitsch Melissa D | Prion-specific peptide reagents |
US20050181353A1 (en) * | 2004-02-17 | 2005-08-18 | Rao Galla C. | Stabilization of cells and biological specimens for analysis |
US8189899B2 (en) | 2004-07-30 | 2012-05-29 | Veridex, Llc | Methods and algorithms for cell enumeration in a low-cost cytometer |
JP5537771B2 (ja) | 2004-08-17 | 2014-07-02 | ベリデックス・リミテッド・ライアビリティ・カンパニー | 循環する希少細胞の分析用の画像診断機器 |
WO2006076683A2 (en) * | 2005-01-13 | 2006-07-20 | Novartis Vaccines And Diagnostics Inc. | Isolation and detection of pathogenic prions |
CN101166976B (zh) * | 2005-01-13 | 2013-06-12 | 诺华疫苗和诊断公司 | 利用朊病毒特异性肽试剂的elisa试验 |
US7777885B2 (en) * | 2005-08-17 | 2010-08-17 | Veridex, Llc | Diagnostic imaging device for the analysis of circulating rare cells |
AU2006287299B2 (en) | 2005-09-09 | 2012-08-23 | Novartis Ag | Prion-specific peptoid reagents |
US8337755B2 (en) * | 2006-03-13 | 2012-12-25 | Veridex, Llc | Operator independent programmable sample preparation and analysis system |
CN101583722A (zh) | 2006-07-14 | 2009-11-18 | 阿维瓦生物科学股份有限公司 | 从生物学样品检测稀有细胞的方法和组合物 |
US8003314B2 (en) | 2007-04-16 | 2011-08-23 | Diagnostic Hybrids, Inc. | Methods for direct fluorescent antibody virus detection in liquids |
US7828968B2 (en) | 2007-08-30 | 2010-11-09 | Veridex, Llc | Method and apparatus for imaging target components in a biological sample using permanent magnets |
US20090061456A1 (en) * | 2007-08-30 | 2009-03-05 | Allard William J | Method for predicting progression free and overall survival at each follow-up time point during therapy of metastatic breast cancer patients using circulating tumor cells |
US8110101B2 (en) * | 2007-08-30 | 2012-02-07 | Veridex, Llc | Method and apparatus for imaging target components in a biological sample using permanent magnets |
US20090117532A1 (en) * | 2007-11-01 | 2009-05-07 | Doyle Gerald V | Pre-clinical method for monitoring serial changes in circulating breast cancer cells in mice |
KR101604649B1 (ko) * | 2007-11-27 | 2016-03-18 | 베리덱스, 엘엘씨 | 혈액 내 순환 흑색종 세포의 자동화된 계산 및 특징화 |
EP2229441B1 (en) | 2007-12-12 | 2014-10-01 | The Board of Trustees of The Leland Stanford Junior University | Method and apparatus for magnetic separation of cells |
US20090191535A1 (en) * | 2007-12-22 | 2009-07-30 | Mark Carle Connelly | Method of assessing metastatic carcinomas from circulating endothelial cells and disseminated tumor cells |
KR101384142B1 (ko) * | 2007-12-28 | 2014-04-14 | 삼성디스플레이 주식회사 | 표시기판, 이의 제조방법 및 이를 갖는 표시장치 |
US9078932B2 (en) * | 2008-02-04 | 2015-07-14 | Emmetrope, Inc. | Magnetic cells for localizing delivery and tissue repair |
AU2009243060A1 (en) * | 2008-04-30 | 2009-11-05 | Novartis Ag. | Assay for pathogenic conformers |
WO2010044005A2 (en) * | 2008-10-16 | 2010-04-22 | Koninklijke Philips Electronics N.V. | Method and device for determining the amount of magnetically labeled target components |
WO2010068812A1 (en) | 2008-12-10 | 2010-06-17 | Abqmr, Inc. | Nuclear magnetic resonance apparatus, methods and associated technology |
US20120077246A1 (en) | 2009-04-24 | 2012-03-29 | The Board Of Trustees Of The University Of Illinoi | Methods and Devices for Capturing Circulating Tumor Cells |
US8790916B2 (en) | 2009-05-14 | 2014-07-29 | Genestream, Inc. | Microfluidic method and system for isolating particles from biological fluid |
EP2496947A1 (en) | 2009-11-04 | 2012-09-12 | Novartis AG | Positively charged species as binding reagents in the separation of protein aggregates from monomers |
JP5808349B2 (ja) | 2010-03-01 | 2015-11-10 | カリス ライフ サイエンシズ スウィッツァーランド ホールディングスゲーエムベーハー | セラノーシスのためのバイオマーカー |
WO2011127219A1 (en) | 2010-04-06 | 2011-10-13 | Caris Life Sciences Luxembourg Holdings | Circulating biomarkers for disease |
US8841104B2 (en) | 2010-04-21 | 2014-09-23 | Nanomr, Inc. | Methods for isolating a target analyte from a heterogeneous sample |
US9428547B2 (en) | 2010-04-21 | 2016-08-30 | Dna Electronics, Inc. | Compositions for isolating a target analyte from a heterogeneous sample |
US9476812B2 (en) | 2010-04-21 | 2016-10-25 | Dna Electronics, Inc. | Methods for isolating a target analyte from a heterogeneous sample |
US20110262989A1 (en) | 2010-04-21 | 2011-10-27 | Nanomr, Inc. | Isolating a target analyte from a body fluid |
KR101212029B1 (ko) * | 2011-12-20 | 2012-12-13 | 한국기초과학지원연구원 | 화합물 결합단백질 검출 방법 |
US10000557B2 (en) | 2012-12-19 | 2018-06-19 | Dnae Group Holdings Limited | Methods for raising antibodies |
US9804069B2 (en) | 2012-12-19 | 2017-10-31 | Dnae Group Holdings Limited | Methods for degrading nucleic acid |
US9551704B2 (en) | 2012-12-19 | 2017-01-24 | Dna Electronics, Inc. | Target detection |
US9599610B2 (en) | 2012-12-19 | 2017-03-21 | Dnae Group Holdings Limited | Target capture system |
US9434940B2 (en) | 2012-12-19 | 2016-09-06 | Dna Electronics, Inc. | Methods for universal target capture |
US9995742B2 (en) | 2012-12-19 | 2018-06-12 | Dnae Group Holdings Limited | Sample entry |
US10900969B2 (en) | 2014-03-07 | 2021-01-26 | University Of Illinois Chicago | Biomimetic microfluid device for capturing circulating tumor cells |
EP3998335A3 (en) | 2015-05-08 | 2022-07-27 | Biomagnetic Solutions LLC | Apparatus and method for immunomagnetic cell separation |
EP3301445B1 (en) * | 2016-09-30 | 2020-03-18 | ARKRAY, Inc. | Method for magnetically labeling particles |
JP6754345B2 (ja) * | 2016-09-30 | 2020-09-09 | アークレイ株式会社 | 粒子の磁気標識方法及び標識装置 |
US11413378B2 (en) | 2018-05-08 | 2022-08-16 | Biomagnetic Solutions Llc | Rigid chamber for cell separation from a flexible disposable bag |
EP3693739A1 (de) * | 2019-02-06 | 2020-08-12 | Stefan Schreier | Verfahren und vorrichtung zur isolierung von gewünschten zellen aus einer probe nicht-magnetischer biologischer materialien |
Family Cites Families (14)
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US3970518A (en) | 1975-07-01 | 1976-07-20 | General Electric Company | Magnetic separation of biological particles |
US4018886A (en) | 1975-07-01 | 1977-04-19 | General Electric Company | Diagnostic method and device employing protein-coated magnetic particles |
US4267234A (en) | 1978-03-17 | 1981-05-12 | California Institute Of Technology | Polyglutaraldehyde synthesis and protein bonding substrates |
US4375407A (en) | 1981-06-22 | 1983-03-01 | The Franklin Institute | High gradient magnetic separation device |
US4554088A (en) | 1983-05-12 | 1985-11-19 | Advanced Magnetics Inc. | Magnetic particles for use in separations |
US4795698A (en) | 1985-10-04 | 1989-01-03 | Immunicon Corporation | Magnetic-polymer particles |
US4847193A (en) * | 1987-06-18 | 1989-07-11 | Gene-Trak Systems | Signal amplification in an assay employing a piezoelectric oscillator |
US5215926A (en) | 1988-06-03 | 1993-06-01 | Cellpro, Inc. | Procedure for designing efficient affinity cell separation processes |
US5186827A (en) | 1991-03-25 | 1993-02-16 | Immunicon Corporation | Apparatus for magnetic separation featuring external magnetic means |
WO1996007101A1 (en) * | 1994-08-31 | 1996-03-07 | First Medical, Inc. | Quantitative assays employing magnetizable particles for rate enhancement |
JP3962789B2 (ja) | 1995-02-21 | 2007-08-22 | ダブリュー. シディキー,イクバール | 磁性粒子を利用した混合/分離装置及びその方法 |
JPH08313539A (ja) * | 1995-05-16 | 1996-11-29 | Nittec Co Ltd | 容器およびこの容器を用いた液体撹拌・洗浄・磁性体微粒子捕集方法並びに該容器を用いた免疫化学検査装置 |
US5985153A (en) * | 1996-06-07 | 1999-11-16 | Immunivest Corporation | Magnetic separation apparatus and methods employing an internal magnetic capture gradient and an external transport force |
EP1362918B8 (en) * | 1998-07-01 | 2009-08-05 | Takara Bio Inc. | Gene transfer methods with retroviruses |
-
1999
- 1999-01-29 US US09/240,939 patent/US6551843B1/en not_active Expired - Fee Related
-
2000
- 2000-01-27 CA CA002359664A patent/CA2359664A1/en not_active Abandoned
- 2000-01-27 WO PCT/US2000/002034 patent/WO2000045169A1/en active Application Filing
- 2000-01-27 ES ES00905755T patent/ES2335080T3/es not_active Expired - Lifetime
- 2000-01-27 DE DE60043335T patent/DE60043335D1/de not_active Expired - Lifetime
- 2000-01-27 PT PT00905755T patent/PT1151297E/pt unknown
- 2000-01-27 AT AT00905755T patent/ATE449333T1/de active
- 2000-01-27 JP JP2000596370A patent/JP2002535677A/ja active Pending
- 2000-01-27 DK DK00905755.5T patent/DK1151297T3/da active
- 2000-01-27 EP EP00905755A patent/EP1151297B1/en not_active Expired - Lifetime
- 2000-01-27 AU AU27389/00A patent/AU2738900A/en not_active Abandoned
-
2010
- 2010-07-01 JP JP2010151171A patent/JP5442544B2/ja not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
ATE449333T1 (de) | 2009-12-15 |
WO2000045169A1 (en) | 2000-08-03 |
US6551843B1 (en) | 2003-04-22 |
JP2002535677A (ja) | 2002-10-22 |
CA2359664A1 (en) | 2000-08-03 |
DE60043335D1 (de) | 2009-12-31 |
WO2000045169A9 (en) | 2001-07-26 |
JP5442544B2 (ja) | 2014-03-12 |
EP1151297A1 (en) | 2001-11-07 |
JP2010261963A (ja) | 2010-11-18 |
EP1151297A4 (en) | 2003-04-09 |
EP1151297B1 (en) | 2009-11-18 |
PT1151297E (pt) | 2010-01-20 |
ES2335080T3 (es) | 2010-03-22 |
AU2738900A (en) | 2000-08-18 |
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