DK114629B - Fremgangsmåde til fremstilling af 1-substituerede nitroimidazolforbindelser eller syreadditionssalte deraf. - Google Patents
Fremgangsmåde til fremstilling af 1-substituerede nitroimidazolforbindelser eller syreadditionssalte deraf.Info
- Publication number
- DK114629B DK114629B DK254466AA DK254466A DK114629B DK 114629 B DK114629 B DK 114629B DK 254466A A DK254466A A DK 254466AA DK 254466 A DK254466 A DK 254466A DK 114629 B DK114629 B DK 114629B
- Authority
- DK
- Denmark
- Prior art keywords
- preparation
- acid addition
- addition salts
- nitroimidazole compounds
- substituted nitroimidazole
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/91—Nitro radicals
- C07D233/92—Nitro radicals attached in position 4 or 5
- C07D233/94—Nitro radicals attached in position 4 or 5 with hydrocarbon radicals, substituted by oxygen or sulfur atoms, attached to other ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/68—Halogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/91—Nitro radicals
- C07D233/92—Nitro radicals attached in position 4 or 5
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US45721265A | 1965-05-19 | 1965-05-19 | |
| US76890868A | 1968-10-18 | 1968-10-18 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK114629B true DK114629B (da) | 1969-07-21 |
Family
ID=27038516
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK254466AA DK114629B (da) | 1965-05-19 | 1966-05-18 | Fremgangsmåde til fremstilling af 1-substituerede nitroimidazolforbindelser eller syreadditionssalte deraf. |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US3435049A (pt) |
| BE (1) | BE681144A (pt) |
| BR (1) | BR6679399D0 (pt) |
| CH (1) | CH469716A (pt) |
| DE (1) | DE1695139B2 (pt) |
| DK (1) | DK114629B (pt) |
| FR (1) | FR5448M (pt) |
| GB (3) | GB1099787A (pt) |
| IL (1) | IL25677A (pt) |
| NL (1) | NL148889B (pt) |
| SE (1) | SE337030B (pt) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3700685A (en) * | 1970-05-15 | 1972-10-24 | Merck & Co Inc | Nitroimidazole derivatives |
| US4218449A (en) * | 1978-08-21 | 1980-08-19 | John R. A. Simoons | Treatment of rheumatoid arthritis and related diseases |
| JPS5692887A (en) * | 1979-12-05 | 1981-07-27 | Sumitomo Chem Co Ltd | N-substituted imidazole derivative |
| FR2509302A1 (fr) * | 1981-03-04 | 1983-01-14 | Vyzk Ustav Zuslechtovaci | Composes d'ammonium quaternaire, procede pour leur fabrication et utilisation de ces produits dans les apprets de finissage des tissus |
| DE3218130A1 (de) * | 1982-05-14 | 1983-11-17 | Basf Ag, 6700 Ludwigshafen | Azolylmethyloxirane, verfahren zu ihrer herstellung und diese enthaltende fungizide |
| CH669494GA3 (pt) * | 1984-11-05 | 1989-03-31 | ||
| ZA858242B (en) * | 1985-01-21 | 1986-08-27 | Ciba Geigy Ag | Cationic reaction products formed from 1-aminoalkyl-imidazole compounds and epihalohydrins |
| CH672219B5 (pt) * | 1985-01-25 | 1990-05-15 | Ciba Geigy Ag | |
| FR2624736B1 (fr) * | 1987-12-16 | 1991-03-22 | Dietlin Francois | Nouvelles compositions pharmaceutiques dispersibles dans l'eau a base d'ornidazole |
| DE3825586A1 (de) * | 1988-07-28 | 1990-02-01 | Basf Ag | Substituierte imidazolylmethyloxirane und substituierte imidazolylpropene, ihre herstellung und sie enthaltende fungizide |
| FR2647448B1 (fr) * | 1989-05-23 | 1991-08-23 | Rhone Poulenc Sante | Procede de preparation du (chloro-3 hydroxy-2 propyl)-1 methyl-2 nitro-5 imidazole |
| US7368579B2 (en) * | 2002-10-15 | 2008-05-06 | Otsuka Pharmaceutical Co., Ltd. | 1-substituted-4-nitroimidazole compound and process for producing the same |
| CN100338039C (zh) * | 2004-11-29 | 2007-09-19 | 南京圣和药业有限公司 | 奥硝唑光学对映体的制备及纯化方法 |
| CN1314396C (zh) * | 2005-04-28 | 2007-05-09 | 南京圣和药业有限公司 | 左旋奥硝唑在制备抗厌氧菌感染药物的应用 |
| CN1332662C (zh) * | 2005-04-29 | 2007-08-22 | 南京圣和药业有限公司 | 左旋奥硝唑的静脉给药制剂及其制备方法 |
| CN1305469C (zh) * | 2005-07-08 | 2007-03-21 | 南京圣和药业有限公司 | 左旋奥硝唑在制备抗寄生虫感染的药物中的应用 |
| CN100368402C (zh) * | 2005-11-16 | 2008-02-13 | 沈阳中海生物技术开发有限公司 | 奥硝唑光学对映体的制备方法 |
| CN104640451A (zh) * | 2012-07-04 | 2015-05-20 | 雷蒙特亚特特拉维夫大学有限公司 | 用作除草剂的奥硝唑及相关的化合物 |
| CN103073501B (zh) * | 2012-12-07 | 2014-10-15 | 西安万隆制药股份有限公司 | 一种奥硝唑化合物 |
| CN105585532B (zh) * | 2014-10-24 | 2018-05-01 | 山东齐都药业有限公司 | 左奥硝唑反应液的后处理方法 |
| CN105061323A (zh) * | 2015-07-31 | 2015-11-18 | 珠海亿邦制药股份有限公司 | 一种奥硝唑化合物的精制方法 |
| CN107235911A (zh) * | 2016-03-28 | 2017-10-10 | 陕西合成药业股份有限公司 | 一种2-甲基-4-硝基咪唑衍生物及其制备方法和药用组合物的用途 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3275649A (en) * | 1966-09-27 | Process for the preparation of | ||
| US2061377A (en) * | 1934-06-25 | 1936-11-17 | Shell Dev | Conversion of polyhalogenated alcohols |
| US2116439A (en) * | 1936-04-21 | 1938-05-03 | Du Pont | Cyclic oxides and their preparation |
| DE1011618B (de) * | 1954-12-06 | 1957-07-04 | Bayer Ag | Verfahren zur Herstellung basischer Diepoxydharze |
| US3043819A (en) * | 1959-09-15 | 1962-07-10 | Union Carbide Corp | 2-(pyrazol)ethyl acrylates, process for their production, and polymerization products thereof |
| DE1445963A1 (de) * | 1962-04-06 | 1969-12-04 | Klosa Dipl Chem Dr Josef | Verfahren zur Herstellung eines neuen Imidazolderivates |
| FR1379915A (fr) * | 1963-12-17 | 1964-11-27 | Rhone Poulenc Sa | Procédé de préparation de dérivés de l'imidazole |
-
1965
- 1965-05-19 US US457212A patent/US3435049A/en not_active Expired - Lifetime
-
1966
- 1966-04-27 CH CH610766A patent/CH469716A/de unknown
- 1966-04-29 DE DE1966H0059257 patent/DE1695139B2/de active Granted
- 1966-05-01 IL IL25677A patent/IL25677A/en unknown
- 1966-05-11 BR BR179399/66A patent/BR6679399D0/pt unknown
- 1966-05-13 GB GB21427/66A patent/GB1099787A/en not_active Expired
- 1966-05-13 GB GB32761/67A patent/GB1099789A/en not_active Expired
- 1966-05-13 FR FR61416A patent/FR5448M/fr not_active Expired
- 1966-05-13 GB GB32760/67A patent/GB1099788A/en not_active Expired
- 1966-05-17 BE BE681144D patent/BE681144A/xx not_active IP Right Cessation
- 1966-05-18 NL NL666606853A patent/NL148889B/xx not_active IP Right Cessation
- 1966-05-18 SE SE06943/66A patent/SE337030B/xx unknown
- 1966-05-18 DK DK254466AA patent/DK114629B/da unknown
-
1968
- 1968-10-18 US US768908A patent/US3493582A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| GB1099789A (en) | 1968-01-17 |
| SE337030B (pt) | 1971-07-26 |
| GB1099787A (en) | 1968-01-17 |
| BE681144A (pt) | 1966-11-17 |
| IL25677A (en) | 1970-05-21 |
| NL6606853A (pt) | 1966-11-21 |
| DE1695139A1 (de) | 1970-12-17 |
| DE1695139B2 (de) | 1976-11-04 |
| BR6679399D0 (pt) | 1973-10-23 |
| US3435049A (en) | 1969-03-25 |
| GB1099788A (en) | 1968-01-17 |
| NL148889B (nl) | 1976-03-15 |
| CH469716A (de) | 1969-03-15 |
| US3493582A (en) | 1970-02-03 |
| FR5448M (pt) | 1967-10-09 |
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