DK1146041T3 - Derivater af heterocycloalkylbenzocyclobutan og heteroarylbenzocyclobutan og deres anvendelse som inhibitorer for genoptagelse af serotonin og noradrenalin - Google Patents
Derivater af heterocycloalkylbenzocyclobutan og heteroarylbenzocyclobutan og deres anvendelse som inhibitorer for genoptagelse af serotonin og noradrenalinInfo
- Publication number
- DK1146041T3 DK1146041T3 DK01400940T DK01400940T DK1146041T3 DK 1146041 T3 DK1146041 T3 DK 1146041T3 DK 01400940 T DK01400940 T DK 01400940T DK 01400940 T DK01400940 T DK 01400940T DK 1146041 T3 DK1146041 T3 DK 1146041T3
- Authority
- DK
- Denmark
- Prior art keywords
- heterocycloalkylbenzocyclobutane
- heteroarylbenzocyclobutane
- noradrenaline
- reuptake
- serotonin
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/42—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having amino groups or hydroxy groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
- C07D209/16—Tryptamines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/40—Nitrogen atoms, not forming part of a nitro radical, e.g. isatin semicarbazone
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/70—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with ring systems containing two or more relevant rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
- C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/78—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Child & Adolescent Psychology (AREA)
- Pain & Pain Management (AREA)
- Addiction (AREA)
- Anesthesiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Furan Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0004742A FR2807753B1 (fr) | 2000-04-13 | 2000-04-13 | Nouveaux derives d'heterocycloalkylbenzocyclobutane et d'heteroarylbenzocyclobutane, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1146041T3 true DK1146041T3 (da) | 2004-03-22 |
Family
ID=8849212
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK01400940T DK1146041T3 (da) | 2000-04-13 | 2001-04-12 | Derivater af heterocycloalkylbenzocyclobutan og heteroarylbenzocyclobutan og deres anvendelse som inhibitorer for genoptagelse af serotonin og noradrenalin |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US6420413B2 (no) |
| EP (1) | EP1146041B1 (no) |
| JP (1) | JP3761796B2 (no) |
| KR (1) | KR100456795B1 (no) |
| CN (1) | CN1166659C (no) |
| AR (1) | AR028324A1 (no) |
| AT (1) | ATE254102T1 (no) |
| AU (1) | AU777825B2 (no) |
| BR (1) | BR0101444A (no) |
| CA (1) | CA2344255C (no) |
| DE (1) | DE60101177T2 (no) |
| DK (1) | DK1146041T3 (no) |
| EA (1) | EA004473B1 (no) |
| ES (1) | ES2210104T3 (no) |
| FR (1) | FR2807753B1 (no) |
| HK (1) | HK1042477B (no) |
| HU (1) | HUP0101503A3 (no) |
| MX (1) | MXPA01003553A (no) |
| NO (1) | NO318158B1 (no) |
| NZ (1) | NZ511092A (no) |
| PL (1) | PL347056A1 (no) |
| PT (1) | PT1146041E (no) |
| SI (1) | SI1146041T1 (no) |
| TR (1) | TR200302002T4 (no) |
| ZA (1) | ZA200103065B (no) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2508290C (en) * | 2002-12-20 | 2017-02-28 | Ciba Specialty Chemicals Holding Inc. | Synthesis of amines and intermediates for the synthesis thereof |
| US7803894B2 (en) * | 2003-12-05 | 2010-09-28 | 3M Innovatie Properties Company | Coating compositions with perfluoropolyetherisocyanate derived silane and alkoxysilanes |
| CN105541662B (zh) * | 2015-12-28 | 2018-04-17 | 云南大学 | 二氢萘类化合物的固相合成方法 |
| CN107445835B (zh) * | 2017-07-05 | 2020-09-22 | 江苏师范大学 | 一种1,2-二氢环丁烯并[a]萘衍生物及其前体的合成方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1738753B1 (en) * | 1993-06-28 | 2008-04-23 | Wyeth | New treatments using phenethylamine derivatives |
| US5530013A (en) * | 1994-02-14 | 1996-06-25 | American Home Products Corporation | Venlafaxine in the inducement of cognition enhancement |
| WO1995029177A1 (en) * | 1994-04-23 | 1995-11-02 | Smithkline Beecham P.L.C. | Tricyclic derivatives as 5ht2c and 5ht2b antagonists |
| US5506270A (en) * | 1995-01-30 | 1996-04-09 | American Home Products Corporation | Venlafaxine in the treatment of hypothalamic amenorrhea in non-depressed women |
| FR2775687B1 (fr) * | 1998-03-04 | 2000-04-14 | Adir | Nouveaux composes du benzocyclobutane, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
-
2000
- 2000-04-13 FR FR0004742A patent/FR2807753B1/fr not_active Expired - Fee Related
-
2001
- 2001-04-06 MX MXPA01003553A patent/MXPA01003553A/es unknown
- 2001-04-10 JP JP2001111169A patent/JP3761796B2/ja not_active Expired - Fee Related
- 2001-04-11 NO NO20011862A patent/NO318158B1/no unknown
- 2001-04-11 AR ARP010101713A patent/AR028324A1/es unknown
- 2001-04-11 BR BR0101444-7A patent/BR0101444A/pt not_active Application Discontinuation
- 2001-04-12 ZA ZA200103065A patent/ZA200103065B/xx unknown
- 2001-04-12 AT AT01400940T patent/ATE254102T1/de not_active IP Right Cessation
- 2001-04-12 DK DK01400940T patent/DK1146041T3/da active
- 2001-04-12 ES ES01400940T patent/ES2210104T3/es not_active Expired - Lifetime
- 2001-04-12 KR KR10-2001-0019542A patent/KR100456795B1/ko not_active IP Right Cessation
- 2001-04-12 PT PT01400940T patent/PT1146041E/pt unknown
- 2001-04-12 TR TR2003/02002T patent/TR200302002T4/xx unknown
- 2001-04-12 HU HU0101503A patent/HUP0101503A3/hu unknown
- 2001-04-12 DE DE60101177T patent/DE60101177T2/de not_active Expired - Fee Related
- 2001-04-12 NZ NZ511092A patent/NZ511092A/xx unknown
- 2001-04-12 AU AU35187/01A patent/AU777825B2/en not_active Ceased
- 2001-04-12 SI SI200130044T patent/SI1146041T1/xx unknown
- 2001-04-12 EA EA200100343A patent/EA004473B1/ru not_active IP Right Cessation
- 2001-04-12 EP EP01400940A patent/EP1146041B1/fr not_active Expired - Lifetime
- 2001-04-12 US US09/833,827 patent/US6420413B2/en not_active Expired - Fee Related
- 2001-04-13 CN CNB011163860A patent/CN1166659C/zh not_active Expired - Fee Related
- 2001-04-13 PL PL01347056A patent/PL347056A1/xx not_active Application Discontinuation
- 2001-04-17 CA CA002344255A patent/CA2344255C/fr not_active Expired - Fee Related
-
2002
- 2002-03-22 HK HK02102196.6A patent/HK1042477B/zh not_active IP Right Cessation
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