DK1145002T4 - Bioluminescenstest for agonister eller antagonister til en calciumkoblet receptor - Google Patents

Bioluminescenstest for agonister eller antagonister til en calciumkoblet receptor

Info

Publication number
DK1145002T4
DK1145002T4 DK99930956T DK99930956T DK1145002T4 DK 1145002 T4 DK1145002 T4 DK 1145002T4 DK 99930956 T DK99930956 T DK 99930956T DK 99930956 T DK99930956 T DK 99930956T DK 1145002 T4 DK1145002 T4 DK 1145002T4
Authority
DK
Denmark
Prior art keywords
calcium
coupled receptor
agonists
antagonists
bioluminescence test
Prior art date
Application number
DK99930956T
Other languages
Danish (da)
English (en)
Other versions
DK1145002T3 (da
Inventor
Vincent Dupriez
Michel Detheux
Marc Parmentier
Original Assignee
Perkinelmer Cellular Sciences
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8237065&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1145002(T4) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Perkinelmer Cellular Sciences filed Critical Perkinelmer Cellular Sciences
Publication of DK1145002T3 publication Critical patent/DK1145002T3/da
Application granted granted Critical
Publication of DK1145002T4 publication Critical patent/DK1145002T4/da

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6872—Intracellular protein regulatory factors and their receptors, e.g. including ion channels
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
DK99930956T 1998-07-06 1999-07-06 Bioluminescenstest for agonister eller antagonister til en calciumkoblet receptor DK1145002T4 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP98870149 1998-07-06
PCT/BE1999/000087 WO2000002045A2 (fr) 1998-07-06 1999-07-06 Diagnostic a haut rendement et/ou procede de dosage d'un agoniste et/ou antagoniste d'un recepteur a couplage calcium

Publications (2)

Publication Number Publication Date
DK1145002T3 DK1145002T3 (da) 2003-05-05
DK1145002T4 true DK1145002T4 (da) 2009-03-16

Family

ID=8237065

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99930956T DK1145002T4 (da) 1998-07-06 1999-07-06 Bioluminescenstest for agonister eller antagonister til en calciumkoblet receptor

Country Status (9)

Country Link
US (1) US6872538B1 (fr)
EP (1) EP1145002B2 (fr)
JP (1) JP3495987B2 (fr)
AT (1) ATE232298T1 (fr)
CA (1) CA2336929C (fr)
DE (1) DE69905291T3 (fr)
DK (1) DK1145002T4 (fr)
ES (1) ES2192060T5 (fr)
WO (1) WO2000002045A2 (fr)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6025154A (en) 1995-06-06 2000-02-15 Human Genome Sciences, Inc. Polynucleotides encoding human G-protein chemokine receptor HDGNR10
US6248542B1 (en) 1997-12-09 2001-06-19 Massachusetts Institute Of Technology Optoelectronic sensor
DE10008373C2 (de) * 2000-02-23 2002-11-28 Helmut Adelsberger Verfahren und Vorrichtung zur Bestimmung der Ionenkanalaktivität
CN100507003C (zh) 2001-02-07 2009-07-01 麻省理工学院 光电子探测系统
US8216797B2 (en) 2001-02-07 2012-07-10 Massachusetts Institute Of Technology Pathogen detection biosensor
US7422860B2 (en) 2001-02-07 2008-09-09 Massachusetts Institute Of Technology Optoelectronic detection system
WO2002075273A2 (fr) * 2001-03-20 2002-09-26 Euroscreen S.A. Dispositif et procede de triage, de diagnostic et/ou de dosage d'un agoniste et/ou antagoniste d'un recepteur couple au calcium
GB0108143D0 (en) * 2001-03-31 2001-05-23 Univ Dundee High-throughput screen
WO2003057730A1 (fr) 2002-01-07 2003-07-17 Euroscreen S.A. Ligand du recepteur gpr43 couple a une proteine g et utilisations de ce ligand
JP2006519763A (ja) 2002-11-08 2006-08-31 アブリンクス エン．ヴェー． 治療用ポリペプチドの投与法およびそのためのポリペプチド
GB0228139D0 (en) * 2002-12-03 2003-01-08 Kozlova Zwinderman Olga Fungal biosensor for contaminant detection
NZ540771A (en) 2003-01-10 2009-05-31 Ablynx Nv Recombinant VHH single domain antibody from camelidae against von willebrand factor (vWF) or against collagen
ATE485307T1 (de) 2003-11-07 2010-11-15 Ablynx Nv Camelidae schwere ketten antikörper vhhs gegen epidermalen wachstumfaktor rezeptor (egfr) und ihre verwendung
ITMI20040598A1 (it) * 2004-03-26 2004-06-26 Carlotta Giorgi Metodo per la rilevazione di parametri intracellulari con sonde proteiche luminescenti per lo screening di molecole in grado di alterare detti parametri
CA2810292C (fr) 2004-05-14 2015-09-29 Euroscreen S.A. Ligand pour recepteur fprl2 couple aux proteines g et leur utilisation
EP1888640B1 (fr) 2005-05-18 2012-03-14 Ablynx N.V. Nanocorps ameliores utilises contre le facteur-alpha de necrose tumorale
MX2007014564A (es) 2005-05-20 2008-02-07 Ablynx Nv Anticuerpos de vhh de dominio unico contra el factor de von willebrand.
WO2007100618A2 (fr) * 2006-02-23 2007-09-07 Atto Bioscience Nouveaux dosages cellulaires de la phosphodiestérase
US20080287371A1 (en) * 2007-05-17 2008-11-20 Tranzyme Pharma Inc. Macrocyclic antagonists of the motilin receptor for modulation of the migrating motor complex
JP2012533298A (ja) 2009-07-14 2012-12-27 イー・エム・デイー・ミリポア・コーポレイシヨン カルシウム親和性の増加と生物発光の増強を示す改変型発光蛋白質及びその使用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5422266A (en) 1984-12-31 1995-06-06 University Of Georgia Research Foundation, Inc. Recombinant DNA vectors capable of expressing apoaequorin
JPH01285196A (ja) 1988-05-11 1989-11-16 Chisso Corp 発光蛋白エクオリンの製造法
JPH02253162A (ja) † 1989-03-27 1990-10-11 Chisso Corp 特異的結合能を有する物質と結合したエクオリンを用いる検出法
EP0372352B1 (fr) † 1988-12-06 1995-06-07 Chisso Corporation Aéquorine fusionnée avec une protéine ayant une activité de liaison spécifique, sa préparation, sa purification et méthode de détection l'utilisant
JPH03153700A (ja) † 1989-11-09 1991-07-01 Chisso Corp 物理吸着法により担体に固定化されたエクオリン活性を示す蛋白質
US5714666A (en) † 1993-02-09 1998-02-03 Children's Hospital Of Philadelphia Measurement of intracellular calcium using bioluminescent apoaequorin expressed in mammalian cells
US5744320A (en) † 1995-06-07 1998-04-28 Promega Corporation Quenching reagents and assays for enzyme-mediated luminescence

Also Published As

Publication number Publication date
ES2192060T3 (es) 2003-09-16
DE69905291T3 (de) 2009-06-25
EP1145002B2 (fr) 2008-12-10
WO2000002045A3 (fr) 2001-11-08
CA2336929C (fr) 2005-10-04
ES2192060T5 (es) 2009-05-01
JP3495987B2 (ja) 2004-02-09
DK1145002T3 (da) 2003-05-05
CA2336929A1 (fr) 2000-01-13
EP1145002B1 (fr) 2003-02-05
WO2000002045A2 (fr) 2000-01-13
JP2002519699A (ja) 2002-07-02
DE69905291T2 (de) 2003-11-06
EP1145002A2 (fr) 2001-10-17
US6872538B1 (en) 2005-03-29
DE69905291D1 (de) 2003-03-13
ATE232298T1 (de) 2003-02-15

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