DK1140200T3 - Anthraquinonbaserede antikræftmidler - Google Patents

Anthraquinonbaserede antikræftmidler

Info

Publication number
DK1140200T3
DK1140200T3 DK99959561T DK99959561T DK1140200T3 DK 1140200 T3 DK1140200 T3 DK 1140200T3 DK 99959561 T DK99959561 T DK 99959561T DK 99959561 T DK99959561 T DK 99959561T DK 1140200 T3 DK1140200 T3 DK 1140200T3
Authority
DK
Denmark
Prior art keywords
anthraquinone
anticancer agents
based anticancer
formula
tertiary
Prior art date
Application number
DK99959561T
Other languages
English (en)
Inventor
Gerard Andrew Potter
Laurence Hylton Patterson
Paul Teesdale-Spittle
Zennia Paniwynk
Original Assignee
Univ Montfort
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Montfort filed Critical Univ Montfort
Application granted granted Critical
Publication of DK1140200T3 publication Critical patent/DK1140200T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/55Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound the modifying agent being also a pharmacologically or therapeutically active agent, i.e. the entire conjugate being a codrug, i.e. a dimer, oligomer or polymer of pharmacologically or therapeutically active compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK99959561T 1998-12-24 1999-12-09 Anthraquinonbaserede antikræftmidler DK1140200T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9828670.1A GB9828670D0 (en) 1998-12-24 1998-12-24 Anthraquinone anticancer drugs
PCT/GB1999/004158 WO2000038734A1 (en) 1998-12-24 1999-12-09 Anthraquinone anticancer drugs

Publications (1)

Publication Number Publication Date
DK1140200T3 true DK1140200T3 (da) 2003-03-10

Family

ID=10845050

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99959561T DK1140200T3 (da) 1998-12-24 1999-12-09 Anthraquinonbaserede antikræftmidler

Country Status (12)

Country Link
US (1) US6465522B1 (da)
EP (1) EP1140200B1 (da)
JP (1) JP2002533418A (da)
AT (1) ATE227588T1 (da)
AU (1) AU759549B2 (da)
CA (1) CA2356399A1 (da)
DE (1) DE69903974T2 (da)
DK (1) DK1140200T3 (da)
ES (1) ES2188273T3 (da)
GB (1) GB9828670D0 (da)
PT (1) PT1140200E (da)
WO (1) WO2000038734A1 (da)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6800615B2 (en) 2002-04-15 2004-10-05 Board Of Trustees Of Michigan State University Antihelminthic anthraquinones and method of use thereof
US20040236414A1 (en) * 2003-05-23 2004-11-25 Brar Balbir S. Devices and methods for treatment of stenotic regions
US20070117784A1 (en) * 2005-03-04 2007-05-24 Novacea, Inc. Treatment of hyperproliferative diseases with anthraquinones
US20070208085A1 (en) * 2006-01-17 2007-09-06 Somanta Limited Potent cytotoxicity and inhibition of pan-cell cycle progression by an alkylating anthraquinone
US8420861B2 (en) * 2007-10-16 2013-04-16 D. Richard Ishmael Anti-tumor compounds derived from 1,4,5,8-tetrachloroanthraquinone
US9040567B2 (en) 2011-08-19 2015-05-26 Emory University BAX agonist, compositions, and methods related thereto
US9980936B2 (en) 2014-05-05 2018-05-29 Emory University BH4 antagonists and methods related thereto
CN108395379A (zh) * 2018-03-30 2018-08-14 南京医科大学康达学院 一种米托蒽醌的半合成方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES472508A1 (es) * 1977-08-15 1979-10-16 American Cyanamid Co Procedimiento para la obtencion de derivados de antraquinona
CS231079B1 (cs) * 1982-07-16 1984-09-17 Libuse Havlickova Způsob přípravy farmakologicky účinných derivátů 1,4-diaminoantrachinonu
JPS60199863A (ja) * 1984-03-23 1985-10-09 Dai Ichi Seiyaku Co Ltd アミノアンスラセン誘導体
EP0182135A3 (en) * 1984-11-19 1987-08-05 American Cyanamid Company Novel bis-(substituted amino) anthraquinones
GB8923075D0 (en) * 1989-10-13 1989-11-29 Patterson Laurence H Anti-cancer compounds
JPH07138212A (ja) * 1993-11-16 1995-05-30 Japan Tobacco Inc アミノアントラキノン化合物及びそれを含有してなる抗腫瘍剤
ATE243520T1 (de) * 1998-02-12 2003-07-15 Univ Montfort Durch hydroxylierung aktivierte wirkstofffreigabe

Also Published As

Publication number Publication date
EP1140200A1 (en) 2001-10-10
JP2002533418A (ja) 2002-10-08
DE69903974T2 (de) 2003-09-04
PT1140200E (pt) 2003-03-31
WO2000038734A1 (en) 2000-07-06
ES2188273T3 (es) 2003-06-16
EP1140200B1 (en) 2002-11-13
AU759549B2 (en) 2003-04-17
US6465522B1 (en) 2002-10-15
CA2356399A1 (en) 2000-07-06
ATE227588T1 (de) 2002-11-15
GB9828670D0 (en) 1999-02-17
AU1670100A (en) 2000-07-31
DE69903974D1 (de) 2002-12-19

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