DK1127068T3 - Immunoterapeutiske fremgangsmåder ved anvendelse af epitoper af WT1 og GATA-1 - Google Patents
Immunoterapeutiske fremgangsmåder ved anvendelse af epitoper af WT1 og GATA-1Info
- Publication number
- DK1127068T3 DK1127068T3 DK99952682T DK99952682T DK1127068T3 DK 1127068 T3 DK1127068 T3 DK 1127068T3 DK 99952682 T DK99952682 T DK 99952682T DK 99952682 T DK99952682 T DK 99952682T DK 1127068 T3 DK1127068 T3 DK 1127068T3
- Authority
- DK
- Denmark
- Prior art keywords
- peptide
- gata
- epitopes
- polypeptide
- variant
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9823897.5A GB9823897D0 (en) | 1998-11-02 | 1998-11-02 | Immunotherapeutic methods and molecules |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1127068T3 true DK1127068T3 (da) | 2006-05-08 |
Family
ID=10841650
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK99952682T DK1127068T3 (da) | 1998-11-02 | 1999-11-02 | Immunoterapeutiske fremgangsmåder ved anvendelse af epitoper af WT1 og GATA-1 |
Country Status (14)
Country | Link |
---|---|
US (3) | US7326767B1 (de) |
EP (2) | EP1127068B1 (de) |
JP (2) | JP2003500004A (de) |
AT (2) | ATE405587T1 (de) |
AU (1) | AU770752B2 (de) |
CA (2) | CA2773380A1 (de) |
CY (1) | CY1105597T1 (de) |
DE (2) | DE69939406D1 (de) |
DK (1) | DK1127068T3 (de) |
ES (2) | ES2311915T3 (de) |
GB (1) | GB9823897D0 (de) |
NZ (1) | NZ511454A (de) |
WO (1) | WO2000026249A1 (de) |
ZA (1) | ZA200103943B (de) |
Families Citing this family (52)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7030212B1 (en) | 1998-07-31 | 2006-04-18 | Haruo Sugiyama | Tumor antigen based on products of the tumor suppressor gene WT1 |
US7901693B2 (en) | 1998-09-30 | 2011-03-08 | Corixa Corporation | Compositions and methods for WT1 specific immunotherapy |
US7655249B2 (en) | 1998-09-30 | 2010-02-02 | Corixa Corporation | Compositions and methods for WT1 specific immunotherapy |
US7329410B1 (en) | 1998-09-30 | 2008-02-12 | Corixa Corporation | Compositions and method for WT1 specific immunotherapy |
US7115272B1 (en) | 1998-09-30 | 2006-10-03 | Corixa Corporation | Compositions and methods for WT1 specific immunotherapy |
US20030235557A1 (en) * | 1998-09-30 | 2003-12-25 | Corixa Corporation | Compositions and methods for WT1 specific immunotherapy |
GB9930616D0 (en) | 1999-12-24 | 2000-02-16 | Mathilda & Terence Kennedy Ins | Activation and inhibition of the immune system |
WO2002051430A2 (en) | 2000-12-22 | 2002-07-04 | Synovis Limited | Methods of modulating toll-related receptor (trr) signaling |
TWI318630B (en) | 2001-03-22 | 2009-12-21 | Int Inst Cancer Immunology Inc | Wt1 modified peptide |
DE60238958D1 (de) * | 2001-06-29 | 2011-02-24 | Chugai Pharmaceutical Co Ltd | Krebsimpfstoff mit einem Krebs-Antigen auf Grundlage des Produkts aus dem Tumorunterdrückungsgen WT1 und einem kationischen Liposom |
US7553494B2 (en) | 2001-08-24 | 2009-06-30 | Corixa Corporation | WT1 fusion proteins |
WO2003028758A1 (fr) * | 2001-09-28 | 2003-04-10 | Haruo Sugiyama | Nouvelle methode d'induction de lymphocytes t specifiques d'un antigene |
JP5230891B2 (ja) | 2001-09-28 | 2013-07-10 | 株式会社癌免疫研究所 | 抗原特異的t細胞の新規な誘導方法 |
US7342092B2 (en) | 2002-09-12 | 2008-03-11 | International Institute Of Cancer Immunology, Inc. | Cancer antigen peptide formulations |
JP4498274B2 (ja) * | 2003-01-15 | 2010-07-07 | 株式会社癌免疫研究所 | 二量体化ペプチド |
US10500257B2 (en) | 2003-06-27 | 2019-12-10 | International Institute Of Cancer Immunology, Inc. | Method of selecting WT1 vaccine adaptive patient |
JP2007516966A (ja) * | 2003-12-01 | 2007-06-28 | スローン−ケターリング インスティチュート フォー キャンサー リサーチ | 合成hla結合ペプチド類似体及びその使用方法 |
GB0328363D0 (en) | 2003-12-06 | 2004-01-14 | Imp College Innovations Ltd | Therapeutically useful molecules |
GB0406415D0 (en) * | 2004-03-22 | 2004-04-21 | Inst Of Cancer Res The | Materials and methods for treatment of cancer |
EP2186896B1 (de) | 2004-03-31 | 2015-11-04 | International Institute of Cancer Immunology, Inc. | Von WT1 abgeleitete Krebs-Antigenpeptide |
PL1642905T3 (pl) * | 2004-10-02 | 2009-04-30 | Immatics Biotechnologies Gmbh | Epitopy immunogenicznych komórek pomocniczych T z antygenów guzów ludzkich oraz sposoby immunoterapeutyczne wykorzystujące te epitopy |
CA2626238C (en) | 2005-10-17 | 2015-10-06 | Sloan Kettering Institute For Cancer Research | Wt1 hla class ii-binding peptides and compositions and methods comprising same |
ES2352855T3 (es) | 2005-11-30 | 2011-02-23 | International Institute Of Cancer Immunology, Inc. | Nuevos compuestos peptídicos del tumor de wilms. |
EP2010209B1 (de) | 2006-04-10 | 2016-06-15 | Sloan Kettering Institute For Cancer Research | Immunogene wt-1-peptide und verfahren zu ihrer verwendung |
KR101323540B1 (ko) | 2007-02-07 | 2013-10-29 | 사이단호진한다이비세이부쯔뵤우겐큐우카이 | 암의 치료제 |
JP5808079B2 (ja) | 2007-03-05 | 2015-11-10 | 株式会社癌免疫研究所 | 癌抗原特異的t細胞のレセプター遺伝子およびそれによりコードされるペプチドならびにそれらの使用 |
EP2228072B1 (de) * | 2007-12-05 | 2018-06-13 | International Institute of Cancer Immunology, Inc. | Krebsimpfstoff-zusammensetzung |
GB0917094D0 (en) | 2009-09-29 | 2009-11-11 | Ucl Biomedica Plc | T-cell receptor |
EP3447140A3 (de) | 2011-06-28 | 2019-05-29 | International Institute of Cancer Immunology, Inc. | Rezeptorgen für peptid-krebs-antigenspezifische t-zellen |
WO2013018778A1 (ja) | 2011-07-29 | 2013-02-07 | 独立行政法人理化学研究所 | ウィルムス腫瘍遺伝子産物またはその断片をコードしている改変型核酸構築物を含んでいる免疫治療用細胞、当該細胞の製造方法、および当該核酸構築物 |
WO2013089252A1 (ja) | 2011-12-14 | 2013-06-20 | 国立大学法人 高知大学 | ヘルパーt細胞誘導性ポリペプチドの改変 |
WO2013106834A2 (en) | 2012-01-13 | 2013-07-18 | Memorial Sloan Kettering Cancer Center | Immunogenic wt-1 peptides and methods of use thereof |
MX361760B (es) * | 2012-05-03 | 2018-12-17 | Hutchinson Fred Cancer Res | Receptores de celulas t con afinidad aumentada y metodos para hacer los mismos. |
SI2945647T1 (sl) | 2013-01-15 | 2021-01-29 | Memorial Sloan Kettering Cancer Center | Imunogeni peptidi WT-1 in postopki za uporabo le-teh |
US10815273B2 (en) | 2013-01-15 | 2020-10-27 | Memorial Sloan Kettering Cancer Center | Immunogenic WT-1 peptides and methods of use thereof |
WO2014142102A1 (ja) | 2013-03-12 | 2014-09-18 | 大日本住友製薬株式会社 | 液体水性組成物 |
EP3461493A1 (de) | 2013-03-29 | 2019-04-03 | Sumitomo Dainippon Pharma Co., Ltd. | Wt1-antigen-peptid-konjugat-vakzin |
US10588952B2 (en) | 2013-03-29 | 2020-03-17 | Sumitomo Dainippon Pharma Co., Ltd. | Conjugate vaccine using trimming function of ERAP1 |
US10682400B2 (en) | 2014-04-30 | 2020-06-16 | President And Fellows Of Harvard College | Combination vaccine devices and methods of killing cancer cells |
US10023841B2 (en) * | 2014-05-23 | 2018-07-17 | Baylor Research Institute | Methods and compositions for treating breast cancer with dendritic cell vaccines |
WO2016022400A1 (en) | 2014-08-04 | 2016-02-11 | Fred Hutchinson Cancer Research Center | T cell immunotherapy specific for wt-1 |
US11596652B2 (en) | 2015-02-18 | 2023-03-07 | Enlivex Therapeutics R&D Ltd | Early apoptotic cells for use in treating sepsis |
US11318163B2 (en) | 2015-02-18 | 2022-05-03 | Enlivex Therapeutics Ltd | Combination immune therapy and cytokine control therapy for cancer treatment |
US11497767B2 (en) | 2015-02-18 | 2022-11-15 | Enlivex Therapeutics R&D Ltd | Combination immune therapy and cytokine control therapy for cancer treatment |
US11304976B2 (en) | 2015-02-18 | 2022-04-19 | Enlivex Therapeutics Ltd | Combination immune therapy and cytokine control therapy for cancer treatment |
IL303543A (en) | 2015-02-18 | 2023-08-01 | Enlivex Therapeutics Rdo Ltd | Combined immunotherapy and cytokine control therapy for cancer treatment |
US11000548B2 (en) | 2015-02-18 | 2021-05-11 | Enlivex Therapeutics Ltd | Combination immune therapy and cytokine control therapy for cancer treatment |
JP6803339B2 (ja) | 2015-04-21 | 2020-12-23 | エンリヴェックス セラピューティクス リミテッド | 治療用のプールされた血液アポトーシス細胞調製物及びそれらの使用 |
CN115531609A (zh) | 2016-02-06 | 2022-12-30 | 哈佛学院校长同事会 | 重塑造血巢以重建免疫 |
KR20180110141A (ko) | 2016-02-18 | 2018-10-08 | 엔리벡스 테라퓨틱스 리미티드 | 암을 치료하기 위한 면역요법과 사이토카인 조절 요법의 조합 |
EP3484448A4 (de) | 2016-07-13 | 2020-04-01 | President and Fellows of Harvard College | Antigenpräsentierende zellmimetische gerüste und verfahren zur herstellung und verwendung davon |
WO2018227205A1 (en) * | 2017-06-09 | 2018-12-13 | President And Fellows Of Harvard College | Compositions for inducing an immune response |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1991007509A1 (en) * | 1989-11-13 | 1991-05-30 | Massachusetts Institute Of Technology | Localization and characterization of the wilms's tumor gene |
US5726288A (en) | 1989-11-13 | 1998-03-10 | Massachusetts Institute Of Technology | Localization and characterization of the Wilms' tumor gene |
WO1991017509A1 (en) | 1990-05-10 | 1991-11-14 | Toshio Tsuyuki | Device and method for interchanging information |
US5731160A (en) | 1992-05-26 | 1998-03-24 | Rijksuniversiteit Leiden | Induction of antigen specific T-lymphocyte responses by stimulation with peptide loaded MHC class I molecules on antigen processing defective mammalian cell lines |
US5622835A (en) * | 1994-04-28 | 1997-04-22 | The Wistar Institute Of Anatomy & Biology | WT1 monoclonal antibodies |
WO1997026328A1 (en) | 1996-01-17 | 1997-07-24 | Imperial College Innovations Limited | Immunotherapy using cytotoxic t lymphocytes (ctl) |
JPH10218093A (ja) | 1997-02-05 | 1998-08-18 | Suzuki Motor Corp | 船外機 |
US7030212B1 (en) * | 1998-07-31 | 2006-04-18 | Haruo Sugiyama | Tumor antigen based on products of the tumor suppressor gene WT1 |
US7144581B2 (en) * | 2000-10-09 | 2006-12-05 | Corixa Corporation | Compositions and methods for WT1 specific immunotherapy |
US7063854B1 (en) * | 1998-09-30 | 2006-06-20 | Corixa Corporation | Composition and methods for WTI specific immunotherapy |
ATE399179T1 (de) * | 1998-09-30 | 2008-07-15 | Corixa Corp | Zusammensetzungen und verfahren für wt1- spezifische immunotherapie |
-
1998
- 1998-11-02 GB GBGB9823897.5A patent/GB9823897D0/en not_active Ceased
-
1999
- 1999-11-02 AU AU64797/99A patent/AU770752B2/en not_active Ceased
- 1999-11-02 JP JP2000579636A patent/JP2003500004A/ja active Pending
- 1999-11-02 CA CA2773380A patent/CA2773380A1/en not_active Abandoned
- 1999-11-02 EP EP99952682A patent/EP1127068B1/de not_active Revoked
- 1999-11-02 AT AT05023645T patent/ATE405587T1/de not_active IP Right Cessation
- 1999-11-02 DE DE69939406T patent/DE69939406D1/de not_active Expired - Lifetime
- 1999-11-02 CA CA2348956A patent/CA2348956C/en not_active Expired - Fee Related
- 1999-11-02 WO PCT/GB1999/003572 patent/WO2000026249A1/en active IP Right Grant
- 1999-11-02 DK DK99952682T patent/DK1127068T3/da active
- 1999-11-02 NZ NZ511454A patent/NZ511454A/xx not_active IP Right Cessation
- 1999-11-02 EP EP05023645A patent/EP1619202B1/de not_active Revoked
- 1999-11-02 DE DE69929533T patent/DE69929533T2/de not_active Expired - Lifetime
- 1999-11-02 AT AT99952682T patent/ATE316099T1/de active
- 1999-11-02 ES ES05023645T patent/ES2311915T3/es not_active Expired - Lifetime
- 1999-11-02 ES ES99952682T patent/ES2252982T3/es not_active Expired - Lifetime
-
2000
- 2000-07-26 US US09/625,963 patent/US7326767B1/en not_active Expired - Fee Related
-
2001
- 2001-05-15 ZA ZA200103943A patent/ZA200103943B/en unknown
-
2006
- 2006-04-03 CY CY20061100465T patent/CY1105597T1/el unknown
-
2007
- 2007-07-06 US US11/825,578 patent/US8529904B2/en not_active Expired - Fee Related
-
2012
- 2012-05-07 JP JP2012105984A patent/JP2012183067A/ja active Pending
-
2013
- 2013-08-14 US US13/966,454 patent/US20140199762A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP1619202B1 (de) | 2008-08-20 |
CA2348956A1 (en) | 2000-05-11 |
DE69929533T2 (de) | 2006-09-07 |
US20080159993A1 (en) | 2008-07-03 |
US20140199762A1 (en) | 2014-07-17 |
US8529904B2 (en) | 2013-09-10 |
ES2311915T3 (es) | 2009-02-16 |
WO2000026249A1 (en) | 2000-05-11 |
AU6479799A (en) | 2000-05-22 |
ATE316099T1 (de) | 2006-02-15 |
AU770752B2 (en) | 2004-03-04 |
US7326767B1 (en) | 2008-02-05 |
EP1127068A1 (de) | 2001-08-29 |
DE69939406D1 (de) | 2008-10-02 |
EP1127068B1 (de) | 2006-01-18 |
ATE405587T1 (de) | 2008-09-15 |
ES2252982T3 (es) | 2006-05-16 |
JP2012183067A (ja) | 2012-09-27 |
EP1619202A3 (de) | 2006-03-08 |
EP1619202A2 (de) | 2006-01-25 |
JP2003500004A (ja) | 2003-01-07 |
NZ511454A (en) | 2004-01-30 |
CA2348956C (en) | 2012-05-22 |
CY1105597T1 (el) | 2010-07-28 |
ZA200103943B (en) | 2003-08-15 |
GB9823897D0 (en) | 1998-12-30 |
CA2773380A1 (en) | 2000-05-11 |
DE69929533D1 (de) | 2006-04-06 |
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