DK1121146T3 - Påvirkning af hyperaktive T-celler med proteolytiske enzymer - Google Patents

Påvirkning af hyperaktive T-celler med proteolytiske enzymer

Info

Publication number
DK1121146T3
DK1121146T3 DK99953778T DK99953778T DK1121146T3 DK 1121146 T3 DK1121146 T3 DK 1121146T3 DK 99953778 T DK99953778 T DK 99953778T DK 99953778 T DK99953778 T DK 99953778T DK 1121146 T3 DK1121146 T3 DK 1121146T3
Authority
DK
Denmark
Prior art keywords
hyperactive
cells
influence
proteolytic enzymes
proteolytic
Prior art date
Application number
DK99953778T
Other languages
English (en)
Inventor
Karl Ransberger
Gerhard Stauder
Original Assignee
Mucos Pharma Gmbh & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mucos Pharma Gmbh & Co filed Critical Mucos Pharma Gmbh & Co
Application granted granted Critical
Publication of DK1121146T3 publication Critical patent/DK1121146T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482—Serine endopeptidases (3.4.21)
    • A61K38/4826—Trypsin (3.4.21.4) Chymotrypsin (3.4.21.1)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/4873—Cysteine endopeptidases (3.4.22), e.g. stem bromelain, papain, ficin, cathepsin H
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55—Protease inhibitors
    • A61K38/57—Protease inhibitors from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21004—Trypsin (3.4.21.4)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/22—Cysteine endopeptidases (3.4.22)
    • C12Y304/22002—Papain (3.4.22.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/22—Cysteine endopeptidases (3.4.22)
    • C12Y304/22033—Fruit bromelain (3.4.22.33), i.e. juice bromelain

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Transplantation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Enzymes And Modification Thereof (AREA)
DK99953778T 1998-10-13 1999-10-12 Påvirkning af hyperaktive T-celler med proteolytiske enzymer DK1121146T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19847114A DE19847114A1 (de) 1998-10-13 1998-10-13 Beeinflussung von hyperaktiven T-Zellen durch proteolytische Enzyme
EP99953778A EP1121146B1 (de) 1998-10-13 1999-10-12 Beeinflussung von hyperaktiven t-zellen durch proteolytische enzyme

Publications (1)

Publication Number Publication Date
DK1121146T3 true DK1121146T3 (da) 2004-10-25

Family

ID=7884290

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99953778T DK1121146T3 (da) 1998-10-13 1999-10-12 Påvirkning af hyperaktive T-celler med proteolytiske enzymer

Country Status (7)

Country Link
EP (1) EP1121146B1 (da)
AT (1) ATE270109T1 (da)
DE (2) DE19847114A1 (da)
DK (1) DK1121146T3 (da)
ES (1) ES2223187T3 (da)
PT (1) PT1121146E (da)
WO (1) WO2000021547A2 (da)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10018980A1 (de) * 2000-04-17 2001-11-08 Mucos Pharma Gmbh & Co Prophylaxe und Therapie von Diabetes mellitus I mit Hilfe proteolytischer Enzyme

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4130221C2 (de) * 1991-09-11 1997-08-07 Mucos Pharma Gmbh Verwendung von proteolytischen Enzymen zur Herstellung eines Medikaments zur Behandlung von Autoimmun-Krankheiten, an deren Entstehung Proteine mit einer C¶H¶2-Domäne beteiligt sind
DE4302060A1 (de) * 1993-01-26 1994-07-28 Mucos Pharma Gmbh & Co Verwendung von Bromelain zur Krebstherapie und/oder Metastasen-Prophylaxe
GB9412711D0 (en) * 1994-06-24 1994-08-17 Cortecs Ltd Medical use of bromelain
DE19726253C2 (de) * 1997-06-20 2000-03-16 Mucos Pharma Gmbh & Co Verwendung von mindestens einem proteolytischen Enzym und Rutosid zur Behandlung von Glomerulonephritis
DE19726255C2 (de) * 1997-06-20 2000-03-16 Mucos Pharma Gmbh & Co Beeinflussung von Cytokinen durch proteolytische Enzyme und Rutosid

Also Published As

Publication number Publication date
EP1121146B1 (de) 2004-06-30
EP1121146A2 (de) 2001-08-08
DE59909869D1 (de) 2004-08-05
WO2000021547A3 (de) 2000-09-08
WO2000021547A2 (de) 2000-04-20
DE19847114A1 (de) 2000-04-20
ATE270109T1 (de) 2004-07-15
ES2223187T3 (es) 2005-02-16
PT1121146E (pt) 2004-10-29

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