DK1121114T3 - Anvendelse af GABA-analoger til fremstilling af et medikament til behandling af mani og bipolære lidelser - Google Patents

Anvendelse af GABA-analoger til fremstilling af et medikament til behandling af mani og bipolære lidelser

Info

Publication number
DK1121114T3
DK1121114T3 DK99941238T DK99941238T DK1121114T3 DK 1121114 T3 DK1121114 T3 DK 1121114T3 DK 99941238 T DK99941238 T DK 99941238T DK 99941238 T DK99941238 T DK 99941238T DK 1121114 T3 DK1121114 T3 DK 1121114T3
Authority
DK
Denmark
Prior art keywords
mania
medication
preparation
treatment
bipolar disorders
Prior art date
Application number
DK99941238T
Other languages
English (en)
Inventor
Atul Chandra Pande
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Application granted granted Critical
Publication of DK1121114T3 publication Critical patent/DK1121114T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK99941238T 1998-10-16 1999-08-18 Anvendelse af GABA-analoger til fremstilling af et medikament til behandling af mani og bipolære lidelser DK1121114T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10453598P 1998-10-16 1998-10-16
PCT/US1999/018981 WO2000023067A1 (en) 1998-10-16 1999-08-18 Method for the treatment of mania and bipolar disorder

Publications (1)

Publication Number Publication Date
DK1121114T3 true DK1121114T3 (da) 2007-04-10

Family

ID=22300998

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99941238T DK1121114T3 (da) 1998-10-16 1999-08-18 Anvendelse af GABA-analoger til fremstilling af et medikament til behandling af mani og bipolære lidelser

Country Status (16)

Country Link
US (1) US6359005B1 (da)
EP (1) EP1121114B1 (da)
JP (1) JP2002527474A (da)
KR (1) KR100697734B1 (da)
AU (1) AU762599B2 (da)
CA (1) CA2344407C (da)
CY (1) CY1106020T1 (da)
DE (1) DE69934813T2 (da)
DK (1) DK1121114T3 (da)
ES (1) ES2279631T3 (da)
HU (1) HUP0103842A3 (da)
IL (1) IL142225A (da)
NZ (1) NZ510920A (da)
PT (1) PT1121114E (da)
WO (1) WO2000023067A1 (da)
ZA (1) ZA200102561B (da)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100491282B1 (ko) 1996-07-24 2005-05-24 워너-램버트 캄파니 엘엘씨 통증 치료용 이소부틸가바 및 그의 유도체
WO2002032376A2 (en) 2000-10-06 2002-04-25 Xenoport, Inc. Bile-acid conjugates for providing sustained systemic concentrations of drugs
EP1343805A4 (en) 2000-10-06 2005-07-20 Xenoport Inc COMPOUNDS DERIVED FROM GALLENIC ACIDS FOR THE PROVISION OF CONTINUING SYSTEMIC CONCENTRATIONS OF MEDICINAL PRODUCTS AFTER ORAL ADMINISTRATION
US7022678B2 (en) * 2001-03-30 2006-04-04 Warner-Lambert Company Pregabalin lactose conjugates
US7186855B2 (en) 2001-06-11 2007-03-06 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
US6818787B2 (en) 2001-06-11 2004-11-16 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
WO2002100344A2 (en) 2001-06-11 2002-12-19 Xenoport, Inc. Amino acid conjugates providing for sustained systemic concentrations of gaba analogues
WO2002100347A2 (en) 2001-06-11 2002-12-19 Xenoport, Inc. Prodrugs of gaba analogs, compositions and uses thereof
US8048917B2 (en) 2005-04-06 2011-11-01 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
US7232924B2 (en) 2001-06-11 2007-06-19 Xenoport, Inc. Methods for synthesis of acyloxyalkyl derivatives of GABA analogs
US6927036B2 (en) 2002-02-19 2005-08-09 Xero Port, Inc. Methods for synthesis of prodrugs from 1-acyl-alkyl derivatives and compositions thereof
WO2003099338A2 (en) 2002-05-17 2003-12-04 Xenoport, Inc. Amino acid conjugates providing for sustained systemic concentrations of gaba analogues
AU2003297927A1 (en) 2002-12-11 2004-06-30 Xenoport, Inc. Prodrugs of fused gaba analogs, pharmaceutical compositions and uses thereof
EP1572187A1 (en) * 2002-12-13 2005-09-14 Warner-Lambert Company LLC Pregabalin and derivatives thereof for the treatment of fibromyalgia and other related disorders
MXPA06003043A (es) 2003-09-17 2006-05-31 Xenoport Inc Tratamiento o prevencion del sindrome piernas inquietas utilizando prodrogas de analogos gaba.
WO2005037784A2 (en) 2003-10-14 2005-04-28 Xenoport, Inc. Crystalline form of gamma-aminobutyric acid analog
DE602005002253T2 (de) * 2004-03-12 2008-05-29 Warner-Lambert Company Llc C1-symmetrische bisphosphinliganden und deren verwendung bei der asymmetrischen synthese von pregabalin
JP2007530657A (ja) * 2004-04-01 2007-11-01 ワーナー−ランバート カンパニー リミテッド ライアビリティー カンパニー Pキラル性ホスホランの調製および不斉合成でのその使用
RS51210B (sr) * 2004-06-21 2010-12-31 Warner-Lambert Company Llc. Dobijanje pregaballina i srodnih jedinjenja
EP1811986B1 (en) 2004-11-04 2014-03-26 XenoPort, Inc. Gabapentin prodrug sustained release oral dosage forms
JP2010043063A (ja) 2008-05-09 2010-02-25 Agency For Science Technology & Research 川崎病の診断及び治療
WO2011141923A2 (en) 2010-05-14 2011-11-17 Lupin Limited Improved synthesis of optically pure (s) - 3-cyano-5-methyl-hexanoic acid alkyl ester, an intermediate of (s)- pregabalin
WO2012059797A1 (en) 2010-11-04 2012-05-10 Lupin Limited Process for synthesis of (s) - pregabalin
KR101035974B1 (ko) * 2011-02-28 2011-05-23 (주) 경화엔지니어링 하수, 폐수 및 침출수 관거용 탈취장치
AU2019271799B2 (en) 2018-05-14 2023-10-12 Xgene Pharmaceutical Inc. Crystalline forms of 1-(acyloxy)-alkyl carbamate drug conjugates of naproxen and pregabalin

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3856816B2 (ja) * 1992-05-20 2006-12-13 ノースウェスターン ユニヴァーシティ 抗発作治療用のgaba及びl−グルタミン酸類縁体
US5510381A (en) * 1995-05-15 1996-04-23 Warner-Lambert Company Method of treatment of mania and bipolar disorder
ATE361909T1 (de) * 1996-10-23 2007-06-15 Warner Lambert Co Substituierte gamma-aminobuttersäurederivate als arzneimittel
WO1999008667A2 (en) * 1997-08-19 1999-02-25 Warner-Lambert Company Methods for treating physiological conditions associated with the use, or sequelae of use, of cocaine or other psychomotor stimulants

Also Published As

Publication number Publication date
HUP0103842A2 (hu) 2002-02-28
JP2002527474A (ja) 2002-08-27
KR20010080165A (ko) 2001-08-22
NZ510920A (en) 2002-08-28
ZA200102561B (en) 2002-09-30
DE69934813D1 (de) 2007-02-22
KR100697734B1 (ko) 2007-03-22
AU5493099A (en) 2000-05-08
CA2344407C (en) 2007-01-09
DE69934813T2 (de) 2007-10-11
ES2279631T3 (es) 2007-08-16
EP1121114B1 (en) 2007-01-10
AU762599B2 (en) 2003-06-26
CY1106020T1 (el) 2011-04-06
PT1121114E (pt) 2007-03-30
CA2344407A1 (en) 2000-04-27
US6359005B1 (en) 2002-03-19
EP1121114A1 (en) 2001-08-08
WO2000023067A1 (en) 2000-04-27
HUP0103842A3 (en) 2003-04-28
IL142225A (en) 2009-09-22

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