DK1108435T3 - Forebyggende midler eller midler mod pancreatitis indeholdende anti-IL-6-receptor-antistoffer som den aktive bestanddel - Google Patents
Forebyggende midler eller midler mod pancreatitis indeholdende anti-IL-6-receptor-antistoffer som den aktive bestanddelInfo
- Publication number
- DK1108435T3 DK1108435T3 DK99938591T DK99938591T DK1108435T3 DK 1108435 T3 DK1108435 T3 DK 1108435T3 DK 99938591 T DK99938591 T DK 99938591T DK 99938591 T DK99938591 T DK 99938591T DK 1108435 T3 DK1108435 T3 DK 1108435T3
- Authority
- DK
- Denmark
- Prior art keywords
- agents
- active ingredient
- pancreatitis
- receptor antibodies
- containing anti
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/244—Interleukins [IL]
- C07K16/248—IL-6
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP25179698 | 1998-08-24 | ||
JP5430299 | 1999-03-02 | ||
PCT/JP1999/004533 WO2000010607A1 (fr) | 1998-08-24 | 1999-08-23 | Produits preventifs ou therapeutiques de la pancreatite contenant des antagonistes de il-6 comme substance active |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1108435T3 true DK1108435T3 (da) | 2007-02-05 |
Family
ID=26395047
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK99938591T DK1108435T3 (da) | 1998-08-24 | 1999-08-23 | Forebyggende midler eller midler mod pancreatitis indeholdende anti-IL-6-receptor-antistoffer som den aktive bestanddel |
Country Status (11)
Country | Link |
---|---|
US (1) | US8440196B1 (fr) |
EP (1) | EP1108435B1 (fr) |
JP (1) | JP4711507B2 (fr) |
AT (1) | ATE350060T1 (fr) |
AU (1) | AU757261B2 (fr) |
CA (1) | CA2341239C (fr) |
DE (1) | DE69934698T2 (fr) |
DK (1) | DK1108435T3 (fr) |
ES (1) | ES2276525T3 (fr) |
PT (1) | PT1108435E (fr) |
WO (1) | WO2000010607A1 (fr) |
Families Citing this family (51)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE547119T1 (de) | 1997-03-21 | 2012-03-15 | Chugai Pharmaceutical Co Ltd | Präventives oder therapeutisches mittel mit einem il-6-antagonisten als wirkstoff für durch sensibilisierte t-zellen vermittelte erkrankungen |
UA80091C2 (en) | 2001-04-02 | 2007-08-27 | Chugai Pharmaceutical Co Ltd | Remedies for infant chronic arthritis-relating diseases and still's disease which contain an interleukin-6 (il-6) antagonist |
EP3578168A1 (fr) | 2002-02-14 | 2019-12-11 | Chugai Seiyaku Kabushiki Kaisha | Formulation de solutions contenant des anticorps comprenant un sucre comme stabilisant |
GB2401040A (en) * | 2003-04-28 | 2004-11-03 | Chugai Pharmaceutical Co Ltd | Method for treating interleukin-6 related diseases |
CA2539061A1 (fr) * | 2003-09-22 | 2005-03-31 | Biovation Gmbh & Co. Kg | Utilisation d'un agoniste de l'il-6 pour le traitement de maladies mediees par l'il-6 |
AR048335A1 (es) | 2004-03-24 | 2006-04-19 | Chugai Pharmaceutical Co Ltd | Agentes terapeuticos para trastornos del oido interno que contienen un antagonista de il- 6 como un ingrediente activo |
JPWO2005090405A1 (ja) | 2004-03-24 | 2008-04-17 | 中外製薬株式会社 | インターロイキン−6受容体に対するヒト型化抗体のサブタイプ |
EP1941907B1 (fr) * | 2005-10-14 | 2016-03-23 | Fukuoka University | Inhibiteur de dysfonctionnement d'îlots transplantés dans un transplant d'îlots |
KR101239051B1 (ko) | 2005-10-21 | 2013-03-04 | 추가이 세이야쿠 가부시키가이샤 | 심장질환 치료제 |
AR057582A1 (es) | 2005-11-15 | 2007-12-05 | Nat Hospital Organization | Agentes para suprimir la induccion de linfocitos t citotoxicos |
CN101370521A (zh) | 2006-01-27 | 2009-02-18 | 学校法人庆应义塾 | 伴有脉络膜血管生成的疾病的治疗药 |
CA2648644C (fr) | 2006-04-07 | 2016-01-05 | Osaka University | Promoteur de regeneration musculaire |
US8080248B2 (en) | 2006-06-02 | 2011-12-20 | Regeneron Pharmaceuticals, Inc. | Method of treating rheumatoid arthritis with an IL-6R antibody |
ES2398076T3 (es) | 2006-06-02 | 2013-03-13 | Regeneron Pharmaceuticals, Inc. | Anticuerpos de alta afinidad contra el receptor de IL-6 humano |
MX2009001110A (es) | 2006-08-03 | 2009-05-11 | Vaccinex Inc | Anticuerpos monoclonales anti-il-6 y usos de los mismos. |
JP2010095445A (ja) * | 2006-12-27 | 2010-04-30 | Tokyo Medical & Dental Univ | Il−6アンタゴニストを有効成分とする炎症性筋疾患治療剤 |
CN101646459B (zh) | 2007-01-23 | 2014-02-12 | 国立大学法人信州大学 | 慢性排斥反应抑制剂 |
US9981415B2 (en) | 2007-09-10 | 2018-05-29 | Ehc Canada, Inc. | Method and apparatus for extrusion of thermoplastic handrail |
PE20091174A1 (es) | 2007-12-27 | 2009-08-03 | Chugai Pharmaceutical Co Ltd | Formulacion liquida con contenido de alta concentracion de anticuerpo |
CN102089326B (zh) | 2008-05-13 | 2014-12-31 | 诺维莫尼公司 | 抗白细胞介素-6/白细胞介素-6受体的抗体及其使用方法 |
WO2009148148A1 (fr) | 2008-06-05 | 2009-12-10 | 国立がんセンター総長が代表する日本国 | Inhibiteur de neuro-invasion |
US8188235B2 (en) | 2008-06-18 | 2012-05-29 | Pfizer Inc. | Antibodies to IL-6 and their uses |
EP2408454A2 (fr) | 2009-03-18 | 2012-01-25 | Resverlogix Corp. | Nouveaux agents anti-inflammatoires |
JP5813626B2 (ja) | 2009-04-22 | 2015-11-17 | レスバーロジックス コーポレイション | 新規抗炎症剤 |
ES2622366T3 (es) * | 2009-10-26 | 2017-07-06 | F. Hoffmann-La Roche Ag | Procedimiento para la producción de una inmunoglobulina glucosilada |
JO3417B1 (ar) | 2010-01-08 | 2019-10-20 | Regeneron Pharma | الصيغ المستقرة التي تحتوي على الأجسام المضادة لمضاد مستقبل( interleukin-6 (il-6r |
HRP20221490T1 (hr) | 2010-05-28 | 2023-02-03 | Chugai Seiyaku Kabushiki Kaisha | Poboljšanje antitumorskog odgovora t stanice |
EP2578233B1 (fr) * | 2010-05-28 | 2017-04-26 | National Cancer Center | Agent thérapeutique contre le cancer du pancréas |
EP3351559A3 (fr) | 2010-11-08 | 2018-10-31 | F. Hoffmann-La Roche AG | Anticorps du récepteur anti-il-6 administré par voie sous-cutanée |
WO2012067150A1 (fr) * | 2010-11-16 | 2012-05-24 | 三菱化学株式会社 | Procédé d'essai pour un infarctus cérébral par l'intermédiaire de la protéine de sous-unité bêta du récepteur de l'interleukine 6 |
TWI589299B (zh) | 2011-10-11 | 2017-07-01 | 再生元醫藥公司 | 用於治療類風濕性關節炎之組成物及其使用方法 |
KR101487935B1 (ko) | 2012-05-21 | 2015-02-02 | 한국생명공학연구원 | 곰보배추의 추출물 또는 이의 분획물을 유효성분으로 포함하는, stat3 매개 질환의 예방 또는 치료용 약학적 조성물 |
RU2674996C2 (ru) | 2013-07-04 | 2018-12-14 | Ф. Хоффманн-Ля Рош Аг | Иммуноферментный анализ с подавлением интерференции для определения антител к лекарствам в образцах сыворотки |
US9017678B1 (en) | 2014-07-15 | 2015-04-28 | Kymab Limited | Method of treating rheumatoid arthritis using antibody to IL6R |
JO3789B1 (ar) | 2015-03-13 | 2021-01-31 | Resverlogix Corp | التراكيب والوسائل العلاجية المعتمدة لمعالجة الامراض المتعلقة بالمتممة |
US10160623B2 (en) | 2015-05-07 | 2018-12-25 | Ehc Canada, Inc. | Compact composite handrails with enhanced mechanical properties |
WO2016195088A1 (fr) | 2015-06-04 | 2016-12-08 | 国立研究開発法人 国立精神・神経医療研究センター | Agent thérapeutique contre les maladies mentales ayant un inhibiteur d'il-6 comme principe actif |
CN107708960B (zh) | 2015-06-19 | 2020-08-04 | Ehc加拿大股份公司 | 用于挤出热塑性扶手的方法和设备 |
US11484591B2 (en) | 2016-02-22 | 2022-11-01 | Ohio State Innovation Foundation | Chemoprevention using controlled-release formulations of anti-interleukin 6 agents, synthetic vitamin A analogues or metabolites, and estradiol metabolites |
JP7237834B2 (ja) | 2016-12-14 | 2023-03-13 | ビオラ・セラピューティクス・インコーポレイテッド | 消化管疾病のil-12/il-23阻害薬による治療 |
EP3554541B1 (fr) | 2016-12-14 | 2023-06-07 | Biora Therapeutics, Inc. | Traitement d'une maladie du tractus gastro-intestinal avec une chimoikine/un inhibiteur du récepteur de chimiokine |
WO2018112237A1 (fr) | 2016-12-14 | 2018-06-21 | Progenity Inc. | Traitement d'une maladie du tractus gastro-intestinal avec un inhibiteur de l'il -6 r |
EP3596175A4 (fr) | 2017-03-17 | 2021-01-13 | The Ohio State Innovation Foundation | Nanoparticules pour l'administration d'agents chimiopréventifs |
EP3600416B1 (fr) | 2017-03-30 | 2023-06-07 | Biora Therapeutics, Inc. | Traitement d'une maladie du tractus gastro-intestinal avec un agent immunomodulateur libéré à l'aide d'un dispositif ingérable |
US11851486B2 (en) | 2017-05-02 | 2023-12-26 | National Center Of Neurology And Psychiatry | Method for predicting and evaluating therapeutic effect in diseases related to IL-6 and neutrophils |
KR20200074160A (ko) | 2017-10-20 | 2020-06-24 | 가꼬우호우징 효고 이카다이가쿠 | 항il-6 수용체 항체를 함유하는 수술 후의 유착을 억제하기 위한 의약 조성물 |
EP3810268A1 (fr) | 2018-06-20 | 2021-04-28 | Progenity, Inc. | Traitement d'une maladie du tractus gastro-intestinal avec un inhibiteur d'il-12/il-23 |
US20230041197A1 (en) | 2018-06-20 | 2023-02-09 | Progenity, Inc. | Treatment of a disease of the gastrointestinal tract with an immunomodulator |
US20230009902A1 (en) | 2018-06-20 | 2023-01-12 | Progenity, Inc. | Treatment of a disease or condition in a tissue orginating from the endoderm |
CN114206442A (zh) | 2019-01-31 | 2022-03-18 | 赛诺菲生物技术公司 | 用于治疗幼年特发性关节炎的抗il-6受体抗体 |
WO2020201362A2 (fr) | 2019-04-02 | 2020-10-08 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Méthodes de prédiction et de prévention du cancer chez des patients ayant des lésions prémalignes |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2898040B2 (ja) | 1990-01-26 | 1999-05-31 | 忠三 岸本 | gp130蛋白質に対する抗体 |
US5210075A (en) * | 1990-02-16 | 1993-05-11 | Tanabe Seiyaku Co., Ltd. | Interleukin 6 antagonist peptides |
US5795965A (en) | 1991-04-25 | 1998-08-18 | Chugai Seiyaku Kabushiki Kaisha | Reshaped human to human interleukin-6 receptor |
JPH05304986A (ja) * | 1992-04-28 | 1993-11-19 | Tosoh Corp | gp130蛋白質に対するモノクロ−ナル抗体 |
JP3525221B2 (ja) | 1993-02-17 | 2004-05-10 | 味の素株式会社 | 免疫抑制剤 |
RU2147442C1 (ru) | 1994-10-21 | 2000-04-20 | Кисимото Тадамицу | Фармацевтическая композиция для профилактики или лечения заболеваний, вызываемых образованием il-6 |
IT1274350B (it) | 1994-12-06 | 1997-07-17 | Angeletti P Ist Richerche Bio | Antagonisti di interleuchina-6(il-6) che consistono di forme solubili del ricettore alfa di il-6, mutate nell'interfaccia che si lega a gp 130 |
IT1274782B (it) | 1994-12-14 | 1997-07-24 | Angeletti P Ist Richerche Bio | Metodo per selezionare superagonisti, antagonisti e superantagonisti di ormoni del cui complesso recettoriale fa parte gp 130 |
AU6038196A (en) | 1995-06-07 | 1996-12-30 | Private Biologicals Corporation | Compositions and methods of treating il-6 associated disease s |
-
1999
- 1999-08-23 DE DE69934698T patent/DE69934698T2/de not_active Expired - Lifetime
- 1999-08-23 CA CA2341239A patent/CA2341239C/fr not_active Expired - Fee Related
- 1999-08-23 PT PT99938591T patent/PT1108435E/pt unknown
- 1999-08-23 DK DK99938591T patent/DK1108435T3/da active
- 1999-08-23 AT AT99938591T patent/ATE350060T1/de active
- 1999-08-23 ES ES99938591T patent/ES2276525T3/es not_active Expired - Lifetime
- 1999-08-23 EP EP99938591A patent/EP1108435B1/fr not_active Expired - Lifetime
- 1999-08-23 JP JP2000565927A patent/JP4711507B2/ja not_active Expired - Fee Related
- 1999-08-23 AU AU53049/99A patent/AU757261B2/en not_active Ceased
- 1999-08-23 US US09/762,550 patent/US8440196B1/en not_active Expired - Fee Related
- 1999-08-23 WO PCT/JP1999/004533 patent/WO2000010607A1/fr active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
US8440196B1 (en) | 2013-05-14 |
EP1108435A4 (fr) | 2002-05-08 |
DE69934698D1 (de) | 2007-02-15 |
EP1108435A1 (fr) | 2001-06-20 |
JP4711507B2 (ja) | 2011-06-29 |
ES2276525T3 (es) | 2007-06-16 |
ATE350060T1 (de) | 2007-01-15 |
CA2341239A1 (fr) | 2000-03-02 |
AU757261B2 (en) | 2003-02-13 |
EP1108435B1 (fr) | 2007-01-03 |
PT1108435E (pt) | 2007-04-30 |
AU5304999A (en) | 2000-03-14 |
WO2000010607A1 (fr) | 2000-03-02 |
DE69934698T2 (de) | 2007-10-04 |
CA2341239C (fr) | 2011-01-04 |
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