DK1076646T3 - Fremgangsmåde til stereokemisk styret fremstilling af isomerisk rene höjt substituerede azacykliske forbindelser - Google Patents

Fremgangsmåde til stereokemisk styret fremstilling af isomerisk rene höjt substituerede azacykliske forbindelser

Info

Publication number
DK1076646T3
DK1076646T3 DK99934470T DK99934470T DK1076646T3 DK 1076646 T3 DK1076646 T3 DK 1076646T3 DK 99934470 T DK99934470 T DK 99934470T DK 99934470 T DK99934470 T DK 99934470T DK 1076646 T3 DK1076646 T3 DK 1076646T3
Authority
DK
Denmark
Prior art keywords
isomerically pure
highly substituted
controlled preparation
stereochemically controlled
azacyclic compounds
Prior art date
Application number
DK99934470T
Other languages
Danish (da)
English (en)
Inventor
Michael Reggelin
Timo Heinrich
Bernd Junker
Jochen Antel
Ulf Preuschoff
Original Assignee
Solvay Pharm Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Solvay Pharm Gmbh filed Critical Solvay Pharm Gmbh
Application granted granted Critical
Publication of DK1076646T3 publication Critical patent/DK1076646T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D291/00Heterocyclic compounds containing rings having nitrogen, oxygen and sulfur atoms as the only ring hetero atoms
    • C07D291/02Heterocyclic compounds containing rings having nitrogen, oxygen and sulfur atoms as the only ring hetero atoms not condensed with other rings
    • C07D291/04Five-membered rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C381/00Compounds containing carbon and sulfur and having functional groups not covered by groups C07C301/00 - C07C337/00
    • C07C381/10Compounds containing sulfur atoms doubly-bound to nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/12Oxygen or sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/52Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Indole Compounds (AREA)
DK99934470T 1998-05-13 1999-05-10 Fremgangsmåde til stereokemisk styret fremstilling af isomerisk rene höjt substituerede azacykliske forbindelser DK1076646T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19821418 1998-05-13

Publications (1)

Publication Number Publication Date
DK1076646T3 true DK1076646T3 (da) 2004-09-06

Family

ID=7867628

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99934470T DK1076646T3 (da) 1998-05-13 1999-05-10 Fremgangsmåde til stereokemisk styret fremstilling af isomerisk rene höjt substituerede azacykliske forbindelser

Country Status (29)

Country Link
US (1) US6900322B1 (no)
EP (1) EP1076646B1 (no)
JP (1) JP4503833B2 (no)
KR (1) KR20010043475A (no)
CN (1) CN1252052C (no)
AR (1) AR016247A1 (no)
AT (1) ATE272621T1 (no)
AU (1) AU758192B2 (no)
BR (1) BR9911770A (no)
CA (1) CA2331758C (no)
DE (2) DE19921580A1 (no)
DK (1) DK1076646T3 (no)
DZ (1) DZ2787A1 (no)
ES (1) ES2228074T3 (no)
HK (1) HK1036624A1 (no)
HU (1) HUP0101808A3 (no)
ID (1) ID26787A (no)
IL (1) IL139519A0 (no)
NO (1) NO317986B1 (no)
NZ (1) NZ508043A (no)
PL (1) PL197406B1 (no)
PT (1) PT1076646E (no)
RU (1) RU2225395C2 (no)
SK (1) SK17122000A3 (no)
TR (1) TR200003291T2 (no)
TW (1) TWI220143B (no)
UA (1) UA66859C2 (no)
WO (1) WO1999058500A1 (no)
ZA (1) ZA200006337B (no)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7119207B2 (en) 2000-04-10 2006-10-10 Pfizer Inc Benzoamide piperidine containing compounds and related compounds
KR20020087134A (ko) * 2000-04-10 2002-11-21 화이자 프로덕츠 인크. 벤조아미드 피페리딘 함유 화합물 및 관련 화합물
US7968734B2 (en) * 2004-07-01 2011-06-28 Stc.Unm Organocatalysts and methods of use in chemical synthesis
CN103096893B (zh) 2010-06-04 2016-05-04 阿尔巴尼分子研究公司 甘氨酸转运体-1抑制剂、其制备方法及其用途

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5102877A (en) * 1989-04-28 1992-04-07 Fujisawa Pharmaceutical Co., Ltd. 1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid compounds
TW214545B (no) * 1992-02-17 1993-10-11 Ciba Geigy Ag
US5252747A (en) * 1992-09-11 1993-10-12 Abbott Laboratories Chiral quinolone intermediates

Also Published As

Publication number Publication date
KR20010043475A (ko) 2001-05-25
WO1999058500A1 (de) 1999-11-18
ATE272621T1 (de) 2004-08-15
HUP0101808A3 (en) 2002-05-28
JP2002514624A (ja) 2002-05-21
EP1076646B1 (de) 2004-08-04
PT1076646E (pt) 2004-10-29
NO20005666D0 (no) 2000-11-10
US6900322B1 (en) 2005-05-31
DZ2787A1 (fr) 2003-12-01
CN1252052C (zh) 2006-04-19
BR9911770A (pt) 2001-02-06
ES2228074T3 (es) 2005-04-01
UA66859C2 (uk) 2004-06-15
JP4503833B2 (ja) 2010-07-14
NO317986B1 (no) 2005-01-17
ID26787A (id) 2001-02-08
NZ508043A (en) 2003-05-30
DE59910141D1 (de) 2004-09-09
PL344043A1 (en) 2001-09-24
PL197406B1 (pl) 2008-03-31
AR016247A1 (es) 2001-06-20
CN1299345A (zh) 2001-06-13
CA2331758A1 (en) 1999-11-18
CA2331758C (en) 2009-01-20
SK17122000A3 (sk) 2001-04-09
AU758192B2 (en) 2003-03-20
RU2225395C2 (ru) 2004-03-10
IL139519A0 (en) 2001-11-25
DE19921580A1 (de) 1999-11-25
EP1076646A1 (de) 2001-02-21
WO1999058500B1 (de) 1999-12-29
TWI220143B (en) 2004-08-11
ZA200006337B (en) 2001-05-16
HK1036624A1 (en) 2002-01-11
NO20005666L (no) 2000-11-10
HUP0101808A2 (hu) 2001-09-28
AU5025099A (en) 1999-11-29
TR200003291T2 (tr) 2001-03-21

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