DK107382A - 5beta-hydroxy-delta6-steroider og fremgangsmaade til fremstilling heraf - Google Patents
5beta-hydroxy-delta6-steroider og fremgangsmaade til fremstilling heraf Download PDFInfo
- Publication number
- DK107382A DK107382A DK107382A DK107382A DK107382A DK 107382 A DK107382 A DK 107382A DK 107382 A DK107382 A DK 107382A DK 107382 A DK107382 A DK 107382A DK 107382 A DK107382 A DK 107382A
- Authority
- DK
- Denmark
- Prior art keywords
- beta
- steroids
- pct
- image
- hydrogen
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 150000003431 steroids Chemical class 0.000 title abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 4
- 229910052739 hydrogen Inorganic materials 0.000 abstract 4
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 3
- 125000002252 acyl group Chemical group 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 239000004593 Epoxy Substances 0.000 abstract 1
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 239000002170 aldosterone antagonist Substances 0.000 abstract 1
- 229940083712 aldosterone antagonist Drugs 0.000 abstract 1
- 150000007933 aliphatic carboxylic acids Chemical class 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 150000002431 hydrogen Chemical group 0.000 abstract 1
- 239000012442 inert solvent Substances 0.000 abstract 1
- 229910052500 inorganic mineral Inorganic materials 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 125000000325 methylidene group Chemical group [H]C([H])=* 0.000 abstract 1
- 239000011707 mineral Substances 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 125000001412 tetrahydropyranyl group Chemical group 0.000 abstract 1
- 239000011701 zinc Substances 0.000 abstract 1
- 229910052725 zinc Inorganic materials 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J21/001—Lactones
- C07J21/003—Lactones at position 17
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0003—Androstane derivatives
- C07J1/0018—Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa
- C07J1/0022—Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa the substituent being an OH group free esterified or etherified
- C07J1/0025—Esters
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
- C07J53/002—Carbocyclic rings fused
- C07J53/004—3 membered carbocyclic rings
- C07J53/008—3 membered carbocyclic rings in position 15/16
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0005—Oxygen-containing hetero ring
- C07J71/001—Oxiranes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE3026783A DE3026783C2 (de) | 1980-07-11 | 1980-07-11 | Verfahren zur Herstellung von 5β-Hydroxy-δ↑6↑-steroiden |
| PCT/DE1981/000111 WO1982000294A1 (en) | 1980-07-11 | 1981-07-02 | 5beta-hydroxy-delta 6-steroid derivatives and method for their preparation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK107382A true DK107382A (da) | 1982-03-11 |
Family
ID=6107245
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK107382A DK107382A (da) | 1980-07-11 | 1982-03-11 | 5beta-hydroxy-delta6-steroider og fremgangsmaade til fremstilling heraf |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US4472310A (OSRAM) |
| EP (1) | EP0043994B1 (OSRAM) |
| JP (1) | JPH0128760B2 (OSRAM) |
| AT (1) | ATE7791T1 (OSRAM) |
| CA (1) | CA1156646A (OSRAM) |
| DE (2) | DE3026783C2 (OSRAM) |
| DK (1) | DK107382A (OSRAM) |
| HU (1) | HU182759B (OSRAM) |
| WO (1) | WO1982000294A1 (OSRAM) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2620707B1 (fr) * | 1987-09-18 | 1989-12-08 | Roussel Uclaf | Nouveaux steroides comportant un cycle spirannique a 3, 4 ou 6 chainons en position 17, leur procede et des intermediaires de preparation, leur application comme medicaments et les compositions pharmaceutiques les renfermant |
| CN1047598C (zh) * | 1993-07-06 | 1999-12-22 | 昆明医学院 | 达玛烷型皂甙人参低元醇衍生物及制备方法 |
| US6233871B1 (en) * | 1997-06-11 | 2001-05-22 | I-Chung Ho | Design of planter inserts and water reservoirs |
| ATE403668T1 (de) | 2005-07-21 | 2008-08-15 | Bayer Schering Pharma Ag | Verfahren zur herstellung von 3-oxo-pregn-4-en-21,17-carbolactonen durch die metallfreie oxidation von 17-(3-hydroxypropyl)-3,17- dihydroxyandrostanen |
| SI1910403T1 (sl) | 2005-07-21 | 2016-08-31 | Bayer Pharma AG | Postopek za pripravo 3-okso-pregn-4-en-21,17-karbolaktonov z oksidacijo 17-(3-hidroksipropil)-3,17-dihidroksiandrostanov brez uporabe kovine |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3798213A (en) * | 1971-01-25 | 1974-03-19 | Merck & Co Inc | 7 alpha-methyl-20-spiroxane-3-ones and process |
| DE2251476A1 (de) * | 1972-10-20 | 1974-05-02 | Hoechst Ag | Verfahren zur herstellung von beta(3-keto-7 alpha-thioacyl-17 beta-hydroxy4-androsten-17 alpha -yl)-propionsaeuregamma -lactonen |
| CH609357A5 (OSRAM) * | 1973-05-25 | 1979-02-28 | Schering Ag | |
| US3890304A (en) * | 1973-11-09 | 1975-06-17 | Searle & Co | 7{60 -carbam oyl-17-hydroxy-3-oxo-17{60 -pregn-4-ene-21-carboxylic acid {65 -lactone and related compounds |
| CH626095A5 (OSRAM) * | 1976-04-06 | 1981-10-30 | Ciba Geigy Ag | |
| DE2716485C2 (de) * | 1977-04-14 | 1985-06-05 | Daimler-Benz Ag, 7000 Stuttgart | Eine Zusatzmasse zur Beeinflussung von Resonanzschwingungen aufweisender Drehmomentübertragungsstrang |
-
1980
- 1980-07-11 DE DE3026783A patent/DE3026783C2/de not_active Expired
-
1981
- 1981-07-02 JP JP56502399A patent/JPH0128760B2/ja not_active Expired
- 1981-07-02 WO PCT/DE1981/000111 patent/WO1982000294A1/de not_active Ceased
- 1981-07-02 EP EP81105132A patent/EP0043994B1/de not_active Expired
- 1981-07-02 AT AT81105132T patent/ATE7791T1/de active
- 1981-07-02 HU HU813202A patent/HU182759B/hu not_active IP Right Cessation
- 1981-07-02 US US06/359,713 patent/US4472310A/en not_active Expired - Lifetime
- 1981-07-02 DE DE8181105132T patent/DE3163971D1/de not_active Expired
- 1981-08-20 CA CA000384258A patent/CA1156646A/en not_active Expired
-
1982
- 1982-03-11 DK DK107382A patent/DK107382A/da not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EP0043994B1 (de) | 1984-06-06 |
| DE3026783A1 (de) | 1982-01-28 |
| HU182759B (en) | 1984-03-28 |
| CA1156646A (en) | 1983-11-08 |
| US4472310A (en) | 1984-09-18 |
| JPH0128760B2 (OSRAM) | 1989-06-05 |
| EP0043994A1 (de) | 1982-01-20 |
| DE3026783C2 (de) | 1982-07-29 |
| DE3163971D1 (en) | 1984-07-12 |
| ATE7791T1 (de) | 1984-06-15 |
| WO1982000294A1 (en) | 1982-02-04 |
| JPS57500979A (OSRAM) | 1982-06-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AHS | Application shelved for other reasons than non-payment |