DK1059939T3 - Apparat til at foröge gennemströmningshastigheder af et fluidum i et biologisk væv med mikro-porer - Google Patents

Apparat til at foröge gennemströmningshastigheder af et fluidum i et biologisk væv med mikro-porer

Info

Publication number
DK1059939T3
DK1059939T3 DK99911120T DK99911120T DK1059939T3 DK 1059939 T3 DK1059939 T3 DK 1059939T3 DK 99911120 T DK99911120 T DK 99911120T DK 99911120 T DK99911120 T DK 99911120T DK 1059939 T3 DK1059939 T3 DK 1059939T3
Authority
DK
Denmark
Prior art keywords
fluid
tissue
pores
micro
increasing
Prior art date
Application number
DK99911120T
Other languages
English (en)
Inventor
Jonathan A Eppstein
Original Assignee
Altea Therapeutics Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Altea Therapeutics Corp filed Critical Altea Therapeutics Corp
Application granted granted Critical
Publication of DK1059939T3 publication Critical patent/DK1059939T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0047—Sonopheresis, i.e. ultrasonically-enhanced transdermal delivery, electroporation of a pharmacologically active agent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/0045—Devices for taking samples of body liquids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/18—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
    • A61B18/20—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/0045—Devices for taking samples of body liquids
    • A61B2010/008—Interstitial fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00743—Type of operation; Specification of treatment sites
    • A61B2017/00747—Dermatology
    • A61B2017/00765—Decreasing the barrier function of skin tissue by radiated energy, e.g. using ultrasound, using laser for skin perforation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0092—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin using ultrasonic, sonic or infrasonic vibrations, e.g. phonophoresis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Hematology (AREA)
  • Biophysics (AREA)
  • Medical Informatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Surgical Instruments (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • External Artificial Organs (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK99911120T 1998-03-06 1999-03-05 Apparat til at foröge gennemströmningshastigheder af et fluidum i et biologisk væv med mikro-porer DK1059939T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/036,053 US6173202B1 (en) 1998-03-06 1998-03-06 Method and apparatus for enhancing flux rates of a fluid in a microporated biological tissue
EP99911120A EP1059939B1 (en) 1998-03-06 1999-03-05 Apparatus for enhancing flux rates of a fluid in a microporated biological tissue

Publications (1)

Publication Number Publication Date
DK1059939T3 true DK1059939T3 (da) 2004-12-06

Family

ID=21886346

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99911120T DK1059939T3 (da) 1998-03-06 1999-03-05 Apparat til at foröge gennemströmningshastigheder af et fluidum i et biologisk væv med mikro-porer

Country Status (10)

Country Link
US (2) US6173202B1 (da)
EP (1) EP1059939B1 (da)
JP (3) JP2002505304A (da)
AT (1) ATE273024T1 (da)
AU (1) AU747794B2 (da)
CA (2) CA2329167C (da)
DE (1) DE69919335T2 (da)
DK (1) DK1059939T3 (da)
ES (1) ES2226353T3 (da)
WO (1) WO1999044637A1 (da)

Families Citing this family (190)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060002959A1 (en) * 1996-11-14 2006-01-05 Government Of The United States Skin-sctive adjuvants for transcutaneous immuization
US6797276B1 (en) 1996-11-14 2004-09-28 The United States Of America As Represented By The Secretary Of The Army Use of penetration enhancers and barrier disruption agents to enhance the transcutaneous immune response
US20060002949A1 (en) * 1996-11-14 2006-01-05 Army Govt. Of The Usa, As Rep. By Secretary Of The Office Of The Command Judge Advocate, Hq Usamrmc. Transcutaneous immunization without heterologous adjuvant
US5980898A (en) * 1996-11-14 1999-11-09 The United States Of America As Represented By The U.S. Army Medical Research & Material Command Adjuvant for transcutaneous immunization
US8182473B2 (en) * 1999-01-08 2012-05-22 Palomar Medical Technologies Cooling system for a photocosmetic device
US6517532B1 (en) * 1997-05-15 2003-02-11 Palomar Medical Technologies, Inc. Light energy delivery head
US20060149343A1 (en) * 1996-12-02 2006-07-06 Palomar Medical Technologies, Inc. Cooling system for a photocosmetic device
US6527716B1 (en) 1997-12-30 2003-03-04 Altea Technologies, Inc. Microporation of tissue for delivery of bioactive agents
JP4056091B2 (ja) 1997-05-15 2008-03-05 パロマー・メディカル・テクノロジーズ・インコーポレーテッド 皮膚科的治療方法及び装置
US8313480B2 (en) * 2004-10-02 2012-11-20 Joseph Neev Device and method for treating skin disorders with thermal energy
US7981112B1 (en) 1997-08-12 2011-07-19 Joseph Neev Home use device and methods for treating skin conditions
US20040258703A1 (en) * 1997-11-14 2004-12-23 The Government Of The Us, As Represented By The Secretary Of The Army Skin-active adjuvants for transcutaneous immunization
US6173202B1 (en) * 1998-03-06 2001-01-09 Spectrx, Inc. Method and apparatus for enhancing flux rates of a fluid in a microporated biological tissue
EP1566149A1 (en) 1998-03-12 2005-08-24 Palomar Medical Technologies, Inc. System for electromagnetic radiation of the skin
US6391005B1 (en) 1998-03-30 2002-05-21 Agilent Technologies, Inc. Apparatus and method for penetration with shaft having a sensor for sensing penetration depth
WO1999067645A1 (en) 1998-06-24 1999-12-29 Transderm Diagnostics, Inc. Non-invasive transdermal detection of analytes
AU759738B2 (en) 1998-07-14 2003-04-17 Nitto Denko Corporation Controlled removal of biological membrane by pyrotechnic charge for transmembrane transport
US6059820A (en) 1998-10-16 2000-05-09 Paradigm Medical Corporation Tissue cooling rod for laser surgery
US6611706B2 (en) 1998-11-09 2003-08-26 Transpharma Ltd. Monopolar and bipolar current application for transdermal drug delivery and analyte extraction
US6148232A (en) 1998-11-09 2000-11-14 Elecsys Ltd. Transdermal drug delivery and analyte extraction
US6597946B2 (en) 1998-11-09 2003-07-22 Transpharma Ltd. Electronic card for transdermal drug delivery and analyte extraction
US6708060B1 (en) * 1998-11-09 2004-03-16 Transpharma Ltd. Handheld apparatus and method for transdermal drug delivery and analyte extraction
AU4188100A (en) * 1999-04-08 2000-11-14 Gregory M. Glenn Dry formulation for transcutaneous immunization
US6334851B1 (en) 1999-05-10 2002-01-01 Microfab Technologies, Inc. Method for collecting interstitial fluid from the skin
EP2168497A3 (en) * 1999-06-08 2010-12-01 Altea Therapeutics Corporation Apparatus for microporation of biological membranes using thin film tissue interface devices
US6685699B1 (en) * 1999-06-09 2004-02-03 Spectrx, Inc. Self-removing energy absorbing structure for thermal tissue ablation
US20030078499A1 (en) * 1999-08-12 2003-04-24 Eppstein Jonathan A. Microporation of tissue for delivery of bioactive agents
US6835184B1 (en) 1999-09-24 2004-12-28 Becton, Dickinson And Company Method and device for abrading skin
IL150604A0 (en) * 2000-01-25 2003-02-12 Palomar Medical Tech Inc Method and apparatus for medical treatment utilizing long duration electromagnetic radiation
WO2001076553A2 (en) * 2000-04-06 2001-10-18 Sontra Medical, Inc. Method and device for enhanced transdermal drug delivery
US20040005349A1 (en) * 2000-05-12 2004-01-08 Joseph Neev Opto-thermal material modification
US6595947B1 (en) 2000-05-22 2003-07-22 Becton, Dickinson And Company Topical delivery of vaccines
US7632522B2 (en) 2000-09-28 2009-12-15 Nanocyte Inc. Use of stinging cells/capsules for the delivery of active agents to keratinous substances
IL155097A0 (en) 2000-09-28 2003-10-31 Nanocyte Inc Methods, compositions and devices utilizing stinging cells/capsules for delivering a therapeutic or a cosmetic agent into a tissue
US6882884B1 (en) 2000-10-13 2005-04-19 Soundskin, L.L.C. Process for the stimulation of production of extracellular dermal proteins in human tissue
US8641644B2 (en) 2000-11-21 2014-02-04 Sanofi-Aventis Deutschland Gmbh Blood testing apparatus having a rotatable cartridge with multiple lancing elements and testing means
US20080183162A1 (en) * 2000-12-28 2008-07-31 Palomar Medical Technologies, Inc. Methods And Devices For Fractional Ablation Of Tissue
US20060004306A1 (en) * 2004-04-09 2006-01-05 Palomar Medical Technologies, Inc. Methods and products for producing lattices of EMR-treated islets in tissues, and uses therefor
CN103251453A (zh) * 2000-12-28 2013-08-21 帕洛玛医疗技术有限公司 用于皮肤的emr治疗处理的方法和装置
ATE398461T1 (de) * 2001-02-13 2008-07-15 Us Gov Sec Army Impstoffe zur transkutanen immunisierung gegen reisediarrhö
US6888319B2 (en) * 2001-03-01 2005-05-03 Palomar Medical Technologies, Inc. Flashlamp drive circuit
WO2002069825A2 (en) * 2001-03-02 2002-09-12 Palomar Medical Technologies, Inc. Apparatus and method for photocosmetic and photodermatological treatment
US20060206103A1 (en) * 2001-03-02 2006-09-14 Palomar Medical Technologies, Inc. Dermatological treatment device
US6790179B2 (en) 2001-08-01 2004-09-14 Johnson & Johnson Consumer Companies, Inc. Method of examining and diagnosing skin health
US6855117B2 (en) 2001-08-01 2005-02-15 Johnson & Johnson Consumer Companies, Inc. Method of treating the skin of a subject
US6840910B2 (en) 2001-08-01 2005-01-11 Johnson & Johnson Consumer Companies, Inc. Method of distributing skin care products
EP1395328B1 (en) * 2001-06-08 2006-08-16 Becton, Dickinson and Company Device for manipulating a needle or abrader array
US8337419B2 (en) 2002-04-19 2012-12-25 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
AU2002315177A1 (en) 2001-06-12 2002-12-23 Pelikan Technologies, Inc. Self optimizing lancing device with adaptation means to temporal variations in cutaneous properties
US7682318B2 (en) 2001-06-12 2010-03-23 Pelikan Technologies, Inc. Blood sampling apparatus and method
US7981056B2 (en) 2002-04-19 2011-07-19 Pelikan Technologies, Inc. Methods and apparatus for lancet actuation
US9427532B2 (en) 2001-06-12 2016-08-30 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US9226699B2 (en) 2002-04-19 2016-01-05 Sanofi-Aventis Deutschland Gmbh Body fluid sampling module with a continuous compression tissue interface surface
EP1404235A4 (en) 2001-06-12 2008-08-20 Pelikan Technologies Inc METHOD AND DEVICE FOR A LANZETTING DEVICE INTEGRATED ON A BLOOD CARTRIDGE CARTRIDGE
US9795747B2 (en) 2010-06-02 2017-10-24 Sanofi-Aventis Deutschland Gmbh Methods and apparatus for lancet actuation
ES2352998T3 (es) 2001-06-12 2011-02-24 Pelikan Technologies Inc. Accionador eléctrico de lanceta.
US7025774B2 (en) 2001-06-12 2006-04-11 Pelikan Technologies, Inc. Tissue penetration device
US20040120964A1 (en) * 2001-10-29 2004-06-24 Mikszta John A. Needleless vaccination using chimeric yellow fever vaccine-vectored vaccines against heterologous flaviviruses
EP1439870B1 (en) * 2001-10-29 2009-01-14 Becton, Dickinson and Company Device for the delivery of a substance
EP1450876B1 (en) 2001-11-07 2016-08-17 Syneron Medical Ltd. Integrated transdermal drug delivery system
US20040147984A1 (en) * 2001-11-29 2004-07-29 Palomar Medical Technologies, Inc. Methods and apparatus for delivering low power optical treatments
US20030216719A1 (en) * 2001-12-12 2003-11-20 Len Debenedictis Method and apparatus for treating skin using patterns of optical energy
US20040082940A1 (en) * 2002-10-22 2004-04-29 Michael Black Dermatological apparatus and method
WO2003057059A1 (en) * 2001-12-27 2003-07-17 Palomar Medical Technologies, Inc. Method and apparatus for improved vascular related treatment
US20040073175A1 (en) * 2002-01-07 2004-04-15 Jacobson James D. Infusion system
US7392080B2 (en) * 2002-03-11 2008-06-24 Altea Therapeutics Corporation Transdermal drug delivery patch system, method of making same and method of using same
US8116860B2 (en) * 2002-03-11 2012-02-14 Altea Therapeutics Corporation Transdermal porator and patch system and method for using same
US9918665B2 (en) 2002-03-11 2018-03-20 Nitto Denko Corporation Transdermal porator and patch system and method for using same
ATE394125T1 (de) 2002-03-26 2008-05-15 Nanocyte Inc Nesselzellen mit expression eines exogenen polynucleotids, das ein therapeutisches, diagnostisches oder kosmetisches mittel kodiert, und diese nesselzellen verwendende verfahren, zusammensetzungen und vorrichtungen oder daraus gewonnene kapseln zur abgabe des therapeutischen, diagnostischen oder kosmetischen mittels in ein gewebe
US7892185B2 (en) 2002-04-19 2011-02-22 Pelikan Technologies, Inc. Method and apparatus for body fluid sampling and analyte sensing
US7331931B2 (en) 2002-04-19 2008-02-19 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7297122B2 (en) 2002-04-19 2007-11-20 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8579831B2 (en) 2002-04-19 2013-11-12 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7909778B2 (en) 2002-04-19 2011-03-22 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7674232B2 (en) 2002-04-19 2010-03-09 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7547287B2 (en) 2002-04-19 2009-06-16 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7291117B2 (en) 2002-04-19 2007-11-06 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7229458B2 (en) 2002-04-19 2007-06-12 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7901362B2 (en) 2002-04-19 2011-03-08 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8702624B2 (en) 2006-09-29 2014-04-22 Sanofi-Aventis Deutschland Gmbh Analyte measurement device with a single shot actuator
US8784335B2 (en) 2002-04-19 2014-07-22 Sanofi-Aventis Deutschland Gmbh Body fluid sampling device with a capacitive sensor
US9314194B2 (en) 2002-04-19 2016-04-19 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US7976476B2 (en) 2002-04-19 2011-07-12 Pelikan Technologies, Inc. Device and method for variable speed lancet
US7175642B2 (en) 2002-04-19 2007-02-13 Pelikan Technologies, Inc. Methods and apparatus for lancet actuation
US7717863B2 (en) 2002-04-19 2010-05-18 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8221334B2 (en) 2002-04-19 2012-07-17 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
WO2003089043A2 (en) 2002-04-19 2003-10-30 Transpharma Medical Ltd. Handheld transdermal drug delivery and analyte extraction
US7648468B2 (en) 2002-04-19 2010-01-19 Pelikon Technologies, Inc. Method and apparatus for penetrating tissue
US7232451B2 (en) 2002-04-19 2007-06-19 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7491178B2 (en) 2002-04-19 2009-02-17 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7892183B2 (en) 2002-04-19 2011-02-22 Pelikan Technologies, Inc. Method and apparatus for body fluid sampling and analyte sensing
US9795334B2 (en) 2002-04-19 2017-10-24 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7198606B2 (en) 2002-04-19 2007-04-03 Pelikan Technologies, Inc. Method and apparatus for a multi-use body fluid sampling device with analyte sensing
US9248267B2 (en) 2002-04-19 2016-02-02 Sanofi-Aventis Deustchland Gmbh Tissue penetration device
US20070239142A1 (en) * 2006-03-10 2007-10-11 Palomar Medical Technologies, Inc. Photocosmetic device
US7135033B2 (en) * 2002-05-23 2006-11-14 Palomar Medical Technologies, Inc. Phototreatment device for use with coolants and topical substances
WO2004000098A2 (en) 2002-06-19 2003-12-31 Palomar Medical Technologies, Inc. Method and apparatus for treatment of cutaneous and subcutaneous conditions
CN100482182C (zh) * 2002-06-19 2009-04-29 帕洛玛医疗技术公司 对一定深度的组织进行光热治疗的方法和装置
US20070219605A1 (en) * 2006-03-20 2007-09-20 Palomar Medical Technologies, Inc. Treatment of tissue volume with radiant energy
US20070213792A1 (en) * 2002-10-07 2007-09-13 Palomar Medical Technologies, Inc. Treatment Of Tissue Volume With Radiant Energy
KR20050062597A (ko) * 2002-10-07 2005-06-23 팔로마 메디칼 테크놀로지스, 인코포레이티드 포토바이오스티뮬레이션을 수행하기 위한 장치 및 방법
US20050049522A1 (en) * 2002-10-30 2005-03-03 Allen John J Method of lancing skin for the extraction of blood
US7383084B2 (en) * 2002-10-31 2008-06-03 Transpharma Medical Ltd. Transdermal delivery system for dried particulate or lyophilized medications
IL152574A (en) * 2002-10-31 2009-09-22 Transpharma Medical Ltd A system for passing through the skin of dry items or dried medicines
IL152575A (en) * 2002-10-31 2008-12-29 Transpharma Medical Ltd A skin-to-skin transmission system of water-insoluble drugs
IL152573A (en) * 2002-10-31 2009-11-18 Transpharma Medical Ltd A system for the transmission through the skin of a medical preparation against vomiting and nausea
US8133505B2 (en) * 2002-10-31 2012-03-13 Transpharma Medical Ltd. Transdermal delivery system for dried particulate or lyophilized medications
US7662404B2 (en) * 2002-10-31 2010-02-16 Transpharma Medical Ltd. Transdermal delivery system for dried particulate or lyophilized peptides and polypeptides
WO2004058352A2 (en) * 2002-12-20 2004-07-15 Palomar Medical Technologies, Inc. Apparatus for light treatment of acne and other disorders of follicles
US8574895B2 (en) 2002-12-30 2013-11-05 Sanofi-Aventis Deutschland Gmbh Method and apparatus using optical techniques to measure analyte levels
AU2004213047A1 (en) * 2003-02-19 2004-09-02 Palomar Medical Technologies, Inc. Method and apparatus for treating pseudofolliculitis barbae
ES2441407T3 (es) * 2003-03-27 2014-02-04 The General Hospital Corporation Aparato para tratamiento dermatológico y rejuvenecimiento cutáneo fraccional
US20040193072A1 (en) * 2003-03-28 2004-09-30 Allen John J. Method of analyte measurement using integrated lance and strip
US20040193202A1 (en) * 2003-03-28 2004-09-30 Allen John J. Integrated lance and strip for analyte measurement
US7473264B2 (en) * 2003-03-28 2009-01-06 Lifescan, Inc. Integrated lance and strip for analyte measurement
ES2347248T3 (es) 2003-05-30 2010-10-27 Pelikan Technologies Inc. Procedimiento y aparato para la inyeccion de fluido.
DK1633235T3 (da) 2003-06-06 2014-08-18 Sanofi Aventis Deutschland Apparat til udtagelse af legemsvæskeprøver og detektering af analyt
WO2006001797A1 (en) 2004-06-14 2006-01-05 Pelikan Technologies, Inc. Low pain penetrating
WO2004112689A2 (en) * 2003-06-23 2004-12-29 Transpharma Medical Ltd. Transdermal delivery system for cosmetic agents
IL156789A0 (en) * 2003-07-06 2004-02-08 Adapter for multi-element contact-probe
EP1653876A1 (en) * 2003-07-11 2006-05-10 Reliant Technologies, Inc. Method and apparatus for fractional photo therapy of skin
US8282576B2 (en) 2003-09-29 2012-10-09 Sanofi-Aventis Deutschland Gmbh Method and apparatus for an improved sample capture device
WO2005037095A1 (en) 2003-10-14 2005-04-28 Pelikan Technologies, Inc. Method and apparatus for a variable user interface
US8016811B2 (en) 2003-10-24 2011-09-13 Altea Therapeutics Corporation Method for transdermal delivery of permeant substances
US7299082B2 (en) 2003-10-31 2007-11-20 Abbott Diabetes Care, Inc. Method of calibrating an analyte-measurement device, and associated methods, devices and systems
IL159273A0 (en) * 2003-12-09 2004-06-01 Transpharma Medical Ltd Transdermal delivery system for sustained release of polypeptides
US7822454B1 (en) 2005-01-03 2010-10-26 Pelikan Technologies, Inc. Fluid sampling device with improved analyte detecting member configuration
US7309335B2 (en) * 2003-12-31 2007-12-18 Palomar Medical Technologies, Inc. Dermatological treatment with visualization
WO2005065414A2 (en) 2003-12-31 2005-07-21 Pelikan Technologies, Inc. Method and apparatus for improving fluidic flow and sample capture
US8165651B2 (en) 2004-02-09 2012-04-24 Abbott Diabetes Care Inc. Analyte sensor, and associated system and method employing a catalytic agent
US7699964B2 (en) * 2004-02-09 2010-04-20 Abbott Diabetes Care Inc. Membrane suitable for use in an analyte sensor, analyte sensor, and associated method
US20050187525A1 (en) * 2004-02-19 2005-08-25 Hilgers Michael E. Devices and methods for extracting bodily fluid
EP2343021A1 (en) 2004-04-01 2011-07-13 The General Hospital Corporation Method and apparatus for dermatological treatment and tissue reshaping
US20080132886A1 (en) * 2004-04-09 2008-06-05 Palomar Medical Technologies, Inc. Use of fractional emr technology on incisions and internal tissues
US8828203B2 (en) 2004-05-20 2014-09-09 Sanofi-Aventis Deutschland Gmbh Printable hydrogels for biosensors
US9775553B2 (en) 2004-06-03 2017-10-03 Sanofi-Aventis Deutschland Gmbh Method and apparatus for a fluid sampling device
US7413572B2 (en) * 2004-06-14 2008-08-19 Reliant Technologies, Inc. Adaptive control of optical pulses for laser medicine
US20050284757A1 (en) * 2004-06-29 2005-12-29 Allen John J Analyte measuring system which prevents the reuse of a test strip
US20050284773A1 (en) * 2004-06-29 2005-12-29 Allen John J Method of preventing reuse in an analyte measuring system
US20060024725A1 (en) 2004-07-30 2006-02-02 Robert Hussa Oncofetal fibronectin as a marker for pregnancy-related indications
US20060253176A1 (en) * 2005-02-18 2006-11-09 Palomar Medical Technologies, Inc. Dermatological treatment device with deflector optic
US7704743B2 (en) * 2005-03-30 2010-04-27 Georgia Tech Research Corporation Electrosonic cell manipulation device and method of use thereof
US8834862B2 (en) 2005-04-19 2014-09-16 Nanocyte Inc. Methods, compositions and devices utilizing stinging cells/capsules for conditioning a tissue prior to delivery of an active agent
US7856985B2 (en) 2005-04-22 2010-12-28 Cynosure, Inc. Method of treatment body tissue using a non-uniform laser beam
US20080274166A1 (en) * 2005-06-10 2008-11-06 Transpharma Medical Ltd. Patch for Transdermal Drug Delivery
CA2622560A1 (en) 2005-09-15 2007-03-29 Palomar Medical Technologies, Inc. Skin optical characterization device
JP2009509576A (ja) * 2005-09-26 2009-03-12 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ 皮膚を介した物質抜取り及び／又は物質送出し
WO2007095183A2 (en) * 2006-02-13 2007-08-23 Reliant Technologies, Inc. Laser system for treatment of skin laxity
US20070194717A1 (en) * 2006-02-17 2007-08-23 Palomar Medical Technologies, Inc. Lamp for use in a tissue treatment device
US7885698B2 (en) * 2006-02-28 2011-02-08 Abbott Diabetes Care Inc. Method and system for providing continuous calibration of implantable analyte sensors
WO2007117580A2 (en) * 2006-04-06 2007-10-18 Palomar Medical Technologies, Inc. Apparatus and method for skin treatment with compression and decompression
EP2010276B1 (en) * 2006-04-26 2014-01-22 Covidien LP Multi-stage microporation device
US7586957B2 (en) 2006-08-02 2009-09-08 Cynosure, Inc Picosecond laser apparatus and methods for its operation and use
US20100004582A1 (en) * 2006-10-25 2010-01-07 Pantec Biosolutions Ag Wide-Area Parasystemic Treatment of Skin Related Conditions
US20080161782A1 (en) * 2006-10-26 2008-07-03 Reliant Technologies, Inc. Micropore delivery of active substances
US20080208179A1 (en) * 2006-10-26 2008-08-28 Reliant Technologies, Inc. Methods of increasing skin permeability by treatment with electromagnetic radiation
US20080161666A1 (en) * 2006-12-29 2008-07-03 Abbott Diabetes Care, Inc. Analyte devices and methods
EP2120825B8 (en) 2007-01-22 2017-05-24 Nitto Denko Corporation Transdermal porator and patch system
US20080186591A1 (en) * 2007-02-01 2008-08-07 Palomar Medical Technologies, Inc. Dermatological device having a zoom lens system
WO2008114223A1 (en) * 2007-03-19 2008-09-25 Insuline Medical Ltd. Drug delivery device
US8622991B2 (en) * 2007-03-19 2014-01-07 Insuline Medical Ltd. Method and device for drug delivery
KR20100029235A (ko) * 2007-06-08 2010-03-16 싸이노슈어, 인코포레이티드 외과용 도파관
JP5466161B2 (ja) * 2007-10-09 2014-04-09 トランスファーマ メディカル リミテッド 磁気的なパッチ連結物
CA2696227A1 (en) * 2007-10-17 2009-04-23 Transpharma Medical Ltd. Dissolution rate verification
EP2211918B1 (en) * 2007-10-29 2017-10-18 Syneron Medical Ltd. Vertical patch drying
WO2009072108A2 (en) 2007-12-05 2009-06-11 Syneron Medical Ltd. A disposable electromagnetic energy applicator and method of using it
DE202009017814U1 (de) * 2008-01-17 2010-07-01 Syneron Medical Ltd. Haarentfernungsgerät für die persönliche Anwendung
KR20100115748A (ko) * 2008-01-24 2010-10-28 시네론 메디컬 리미티드 지방 조직 치료 장치, 기기, 및 방법
WO2009124095A1 (en) * 2008-03-31 2009-10-08 Abbott Diabetes Care Inc. Shallow implantable analyte sensor with rapid physiological response
DK2626093T3 (da) * 2008-08-28 2014-02-24 Hoffmann La Roche Anordning til øget subkutan insulinabsorption
CN102159151B (zh) 2008-09-21 2014-11-12 赛诺龙医疗公司 个人皮肤处理方法及装置
US9375169B2 (en) 2009-01-30 2016-06-28 Sanofi-Aventis Deutschland Gmbh Cam drive for managing disposable penetrating member actions with a single motor and motor and control system
US8606366B2 (en) 2009-02-18 2013-12-10 Syneron Medical Ltd. Skin treatment apparatus for personal use and method for using same
US9919168B2 (en) 2009-07-23 2018-03-20 Palomar Medical Technologies, Inc. Method for improvement of cellulite appearance
US8965476B2 (en) 2010-04-16 2015-02-24 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US20120016320A1 (en) * 2010-07-13 2012-01-19 Lin Michael T Method and Device for Liquid Delivery
EP2790684B1 (en) 2011-12-16 2016-10-12 3M Innovative Properties Company Foldable adhesive composite dressing
KR102136901B1 (ko) 2012-04-18 2020-07-22 싸이노슈어, 엘엘씨 피코초 레이저 장치 및 그를 사용한 표적 조직의 치료 방법
WO2014145707A2 (en) 2013-03-15 2014-09-18 Cynosure, Inc. Picosecond optical radiation systems and methods of use
CN105899132B (zh) 2013-12-31 2020-02-18 雅培糖尿病护理公司 自供电分析物传感器以及使用其的装置
US11178823B2 (en) 2014-04-07 2021-11-23 Premier Citrus Apz, Llc Systems and methods for using light energy to facilitate penetration of substances in plants
US9265260B1 (en) 2014-04-07 2016-02-23 Gpd Technologies Llc Systems and methods for using light energy to facilitate penetration of substances in plants
US10278334B2 (en) 2014-04-07 2019-05-07 Premier Citrus Apz, Llc Systems and methods for delivering nucleic acids to a plant
US9459201B2 (en) 2014-09-29 2016-10-04 Zyomed Corp. Systems and methods for noninvasive blood glucose and other analyte detection and measurement using collision computing
US9694992B2 (en) 2014-10-02 2017-07-04 Translogic Corporation Multiple dock station for pneumatic transport system
US11191278B2 (en) 2016-03-25 2021-12-07 Premier Citrus Apz, Llc Systems and methods for delivering nucleic acids to a plant
US9554738B1 (en) 2016-03-30 2017-01-31 Zyomed Corp. Spectroscopic tomography systems and methods for noninvasive detection and measurement of analytes using collision computing
LT3245988T (lt) 2016-05-18 2024-02-12 Sonikure Holdings Limited Ultragarsu pagerinto transsklerinio vaistų pristatymo sistema
EP3759770A4 (en) 2018-02-26 2021-12-08 Cynosure, LLC Q-SWITCHED CAVITY DUMP SUBNANO CUSTOMER LASER
AU2019359469B2 (en) * 2018-10-12 2023-11-30 Immunolight, Llc Methods, devices, and compositions for measuring and inducing cell-to-cell communication, and therapeutic uses thereof

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3964482A (en) 1971-05-17 1976-06-22 Alza Corporation Drug delivery device
US4605670A (en) 1984-02-01 1986-08-12 Nitto Electric Industrial Co., Ltd. Method for percutaneously administering metoclopramide
US4775361A (en) 1986-04-10 1988-10-04 The General Hospital Corporation Controlled removal of human stratum corneum by pulsed laser to enhance percutaneous transport
ATE131081T1 (de) 1988-01-21 1995-12-15 Massachusetts Inst Technology Molekültransport durch gewebe mit der verwendung von elektroporation.
US5088977A (en) * 1988-12-21 1992-02-18 Drug Delivery Systems Inc. Electrical transdermal drug applicator with counteractor and method of drug delivery
JP2703035B2 (ja) * 1989-02-28 1998-01-26 久光製薬株式会社 イオントフォレーゼ用デバイス
EP0429842B1 (en) 1989-10-27 1996-08-28 Korea Research Institute Of Chemical Technology Device for the transdermal administration of protein or peptide drug
US5016615A (en) 1990-02-20 1991-05-21 Riverside Research Institute Local application of medication with ultrasound
US5231975A (en) 1990-02-23 1993-08-03 Cygnus Therapeutic Systems Ultrasound-enhanced delivery of materials into and through the skin
US5115805A (en) 1990-02-23 1992-05-26 Cygnus Therapeutic Systems Ultrasound-enhanced delivery of materials into and through the skin
US5527288A (en) * 1990-12-13 1996-06-18 Elan Medical Technologies Limited Intradermal drug delivery device and method for intradermal delivery of drugs
US5215520A (en) 1991-09-17 1993-06-01 Centre Internationale De Recherches Dermatologiques Galderma (C.I.R.D. Galderma) Method for delivering an active substance topically or percutaneously
US5713845A (en) * 1991-10-29 1998-02-03 Thermolase Corporation Laser assisted drug delivery
US5246437A (en) 1992-04-10 1993-09-21 Abela George S Cell treatment apparatus and method
US5643252A (en) 1992-10-28 1997-07-01 Venisect, Inc. Laser perforator
US5427585A (en) * 1993-03-29 1995-06-27 Bettinger; David S. On-demand iontophoretic system
US5445611A (en) 1993-12-08 1995-08-29 Non-Invasive Monitoring Company (Nimco) Enhancement of transdermal delivery with ultrasound and chemical enhancers
US5458140A (en) 1993-11-15 1995-10-17 Non-Invasive Monitoring Company (Nimco) Enhancement of transdermal monitoring applications with ultrasound and chemical enhancers
US5885211A (en) 1993-11-15 1999-03-23 Spectrix, Inc. Microporation of human skin for monitoring the concentration of an analyte
US5947921A (en) * 1995-12-18 1999-09-07 Massachusetts Institute Of Technology Chemical and physical enhancers and ultrasound for transdermal drug delivery
DE69624668T2 (de) 1995-07-25 2003-08-28 Massachusetts Inst Technology Verbesserter transdermaler transport unter verwendung von ultraschall
CA2199002C (en) 1995-08-29 1999-02-23 Jonathan A. Eppstein Microporation of human skin for drug delivery and monitoring applications
US6183434B1 (en) 1996-07-03 2001-02-06 Spectrx, Inc. Multiple mechanical microporation of skin or mucosa
WO1998029134A2 (en) 1996-12-31 1998-07-09 Altea Technologies, Inc. Microporation of tissue for delivery of bioactive agents
US5999847A (en) * 1997-10-21 1999-12-07 Elstrom; John A. Apparatus and method for delivery of surgical and therapeutic agents
US6022316A (en) 1998-03-06 2000-02-08 Spectrx, Inc. Apparatus and method for electroporation of microporated tissue for enhancing flux rates for monitoring and delivery applications
US6173202B1 (en) * 1998-03-06 2001-01-09 Spectrx, Inc. Method and apparatus for enhancing flux rates of a fluid in a microporated biological tissue

Also Published As

Publication number Publication date
ES2226353T3 (es) 2005-03-16
AU2984099A (en) 1999-09-20
EP1059939A1 (en) 2000-12-20
CA2637760C (en) 2015-01-06
JP2007195999A (ja) 2007-08-09
ATE273024T1 (de) 2004-08-15
AU747794B2 (en) 2002-05-23
US6173202B1 (en) 2001-01-09
CA2329167A1 (en) 1999-09-10
CA2329167C (en) 2008-11-18
JP2002505304A (ja) 2002-02-19
US6508785B1 (en) 2003-01-21
DE69919335T2 (de) 2005-08-11
CA2637760A1 (en) 1999-09-10
WO1999044637A1 (en) 1999-09-10
EP1059939B1 (en) 2004-08-11
JP2011005283A (ja) 2011-01-13
DE69919335D1 (de) 2004-09-16

Similar Documents

Publication Publication Date Title
DK1059939T3 (da) Apparat til at foröge gennemströmningshastigheder af et fluidum i et biologisk væv med mikro-porer
DK1062960T3 (da) Fremgangsmåde til bestemmelse af ydeevnen af en dialysator af en dialyseindretning og dialyseindretning til gennemförsel af fremgangsmåden
WO2000038761A3 (de) Verfahren zur bestimmung des verteilungsvolumens eines blutinhaltsstoffes während einer blutbehandlung und vorrichtung
DK0754072T3 (da) Indretning til lokal indgivelse af et lægemiddel
WO2008037410A8 (de) Vorrichtung und verfahren zur vorgabe einer dialysierflüssigkeitsrate oder blutflussrate für eine extrakorporale blutbehandlung
DE60317886D1 (de) Künstliche herzklappe
DK0867178T3 (da) Non-allosteriske GABA A agonister til behandling af søvnforstyrrelser
ATE506975T1 (de) Blutbehandlungsvorrichtung
DK1539294T3 (da) Apparat til fordeling af væske i en patients krop
ATE466605T1 (de) Blutbehandlungsvorrichtung
DK1519779T3 (da) Filter med dobbelt porøsitet
ATE380563T1 (de) Vorrichtung zur hämodialyse
WO2004064886A3 (de) Verfahren und vorrichtung zur versorgung einer dialysevorrichtung mit dialysierflüssigkeit
TW200724893A (en) Hydraulic device for a blood analysis apparatus, associated method and analysis apparatus equipped with such a device
WO2009070739A3 (en) Systems, devices, and methods for directly energizing water molecule composition
SE0202172L (sv) Anordning och metod för cirkulatorisk isolering och behandling av kroppsdel
EE200300453A (et) Seade ja meetod vedelike töötlemiseks ultraheliga
DE60317906D1 (de) Vitreoretinale tamponaden auf basis von flüssigen fluorsilikonen
EA200200300A1 (ru) Способ и устройство для создания эталонов влажности в газах
AU5126499A (en) Method and apparatus for the preparation and delivery of gas-enriched fluids
DE69513996T2 (de) Vorrichtung und verfahren zur flüssigkeitbehandlung
AU2002228314A1 (en) Means for retaining transcutaneous catheters and needles in place
SE0200381L (sv) Apparat för reducering av fettinnehåll i blod
DE69622473D1 (de) Vorrichtung zur Durchflusskontrolle von Flüssigkeiten, insbesondere zur Infusion von intravenösen Flüssigkeiten
UA3797U (uk) Спосіб лікування тяжких проникаючих поранень ока