DK1056716T3 - Cyclohexandiolderivater - Google Patents

Cyclohexandiolderivater

Info

Publication number
DK1056716T3
DK1056716T3 DK99906250T DK99906250T DK1056716T3 DK 1056716 T3 DK1056716 T3 DK 1056716T3 DK 99906250 T DK99906250 T DK 99906250T DK 99906250 T DK99906250 T DK 99906250T DK 1056716 T3 DK1056716 T3 DK 1056716T3
Authority
DK
Denmark
Prior art keywords
cyclohexanediol derivatives
cyclohexanediol
derivatives
Prior art date
Application number
DK99906250T
Other languages
Danish (da)
English (en)
Inventor
Pierre Barbier
Franz Bauer
Peter Mohr
Marc Muller
Wolfgang Pirson
Original Assignee
Basilea Pharmaceutica Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basilea Pharmaceutica Ag filed Critical Basilea Pharmaceutica Ag
Application granted granted Critical
Publication of DK1056716T3 publication Critical patent/DK1056716T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C17/00Preparation of halogenated hydrocarbons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
    • C07C403/06Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms
    • C07C403/08Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms by hydroxy groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/27Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation
    • C07C45/29Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation of hydroxy groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/27Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation
    • C07C45/29Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation of hydroxy groups
    • C07C45/292Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation of hydroxy groups with chromium derivatives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00Compounds having —CHO groups
    • C07C47/02Saturated compounds having —CHO groups bound to acyclic carbon atoms or to hydrogen
    • C07C47/19Saturated compounds having —CHO groups bound to acyclic carbon atoms or to hydrogen containing hydroxy groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00Compounds having —CHO groups
    • C07C47/20Unsaturated compounds having —CHO groups bound to acyclic carbon atoms
    • C07C47/26Unsaturated compounds having —CHO groups bound to acyclic carbon atoms containing hydroxy groups
    • C07C47/263Unsaturated compounds having —CHO groups bound to acyclic carbon atoms containing hydroxy groups acyclic
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00Compounds having —CHO groups
    • C07C47/20Unsaturated compounds having —CHO groups bound to acyclic carbon atoms
    • C07C47/26Unsaturated compounds having —CHO groups bound to acyclic carbon atoms containing hydroxy groups
    • C07C47/273Unsaturated compounds having —CHO groups bound to acyclic carbon atoms containing hydroxy groups containing halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • C07F7/18Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804Compounds having Si-O-C linkages
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07Optical isomers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/09Geometrical isomers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/12Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK99906250T 1998-02-26 1999-02-20 Cyclohexandiolderivater DK1056716T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP98103346 1998-02-26
PCT/EP1999/001118 WO1999043646A1 (en) 1998-02-26 1999-02-20 Cyclohexanediole derivatives

Publications (1)

Publication Number Publication Date
DK1056716T3 true DK1056716T3 (da) 2003-04-07

Family

ID=8231480

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99906250T DK1056716T3 (da) 1998-02-26 1999-02-20 Cyclohexandiolderivater

Country Status (21)

Country Link
US (1) US6184422B1 (es)
EP (1) EP1056716B1 (es)
JP (1) JP3507435B2 (es)
KR (1) KR20010041313A (es)
CN (1) CN1133621C (es)
AR (1) AR018120A1 (es)
AT (1) ATE229503T1 (es)
AU (1) AU751241B2 (es)
BR (1) BR9908315A (es)
CA (1) CA2320180C (es)
CO (1) CO4980898A1 (es)
DE (1) DE69904442T2 (es)
DK (1) DK1056716T3 (es)
ES (1) ES2188134T3 (es)
MA (1) MA26609A1 (es)
MY (1) MY133520A (es)
PE (1) PE20000267A1 (es)
PT (1) PT1056716E (es)
TR (1) TR200002477T2 (es)
WO (1) WO1999043646A1 (es)
ZA (1) ZA991550B (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1329359C (zh) * 1999-04-01 2007-08-01 埃斯佩里安医疗公司 醚化合物,及其组合物和用途
US6310262B1 (en) 1999-10-18 2001-10-30 Basilea Pharmaceutica Ag Process for preparing retiferol derivatives
EP1094060B1 (en) * 1999-10-18 2004-04-28 Basilea Pharmaceutica AG New process for the preparation of retiferol derivatives
US20040077728A1 (en) * 2000-11-22 2004-04-22 Pierre Barbier Retiferol derivatives and their use in the treatment of skin diseases or conditions associated with photodamage
CA2503801A1 (en) * 2001-12-26 2003-07-10 Chugai Seiyaku Kabushiki Kaisha 2-substituted vitamin d derivatives
US6723755B2 (en) 2002-06-12 2004-04-20 Piotr Chomczynski Method of treating rosacea
US7812057B2 (en) * 2004-08-25 2010-10-12 Molecular Research Center, Inc. Cosmetic compositions
CA2620354C (en) * 2005-08-30 2013-02-05 Wisconsin Alumni Research Foundation Des-c,d analogs of 1.alpha.,25-dihydroxy-19-norvitamin d3
GB0712653D0 (en) 2007-06-28 2007-08-08 Syngenta Ltd Novel herbicides
AU2009206449B2 (en) * 2008-01-22 2014-04-24 Wisconsin Alumni Research Foundation 13,13-Dimethyl-des-C,D analogs of 1alpha, 25-dihydroxy-19-nor-vitamin D3 compounds and topical composition dosage forms and methods of treating skin conditions
AU2010208323B2 (en) * 2009-01-27 2016-03-10 Berg Llc Vitamin D3 and analogs thereof for alleviating side effects associated with chemotherapy
EP2464357B1 (en) 2009-08-14 2019-05-22 Berg LLC Vitamin d3 and analogs thereof for treating alopecia
KR20160013201A (ko) 2013-05-29 2016-02-03 버그 엘엘씨 비타민 d를 이용한 화학요법 유발 탈모증의 예방 또는 완화
CN114044788A (zh) * 2021-08-12 2022-02-15 甘肃皓天医药科技有限责任公司 一种氟骨化醇cd环的制备方法及其应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ271332A (en) 1993-07-09 2001-03-30 Theramex Vitamin D analogues and pharmaceutical use
PL174912B1 (pl) 1994-01-24 1998-10-30 Inst Farmaceutyczny Nowe związki farmakologicznie czynne z grupy witamin D i sposób ich otrzymywania
US5461116A (en) 1994-11-10 1995-10-24 Shell Oil Company Core functionalized star block copolymers
CA2288629A1 (en) * 1997-05-23 1998-11-26 F. Hoffmann-La Roche Ag Cyclohexanediol derivatives

Also Published As

Publication number Publication date
AU751241B2 (en) 2002-08-08
AR018120A1 (es) 2001-10-31
JP2002504537A (ja) 2002-02-12
WO1999043646A1 (en) 1999-09-02
MA26609A1 (fr) 2004-12-20
CN1291974A (zh) 2001-04-18
CN1133621C (zh) 2004-01-07
DE69904442T2 (de) 2003-09-25
AU2624699A (en) 1999-09-15
MY133520A (en) 2007-11-30
US6184422B1 (en) 2001-02-06
BR9908315A (pt) 2000-11-07
EP1056716A1 (en) 2000-12-06
CO4980898A1 (es) 2000-11-27
ATE229503T1 (de) 2002-12-15
CA2320180A1 (en) 1999-09-02
EP1056716B1 (en) 2002-12-11
KR20010041313A (ko) 2001-05-15
TR200002477T2 (tr) 2001-03-21
PE20000267A1 (es) 2000-04-10
JP3507435B2 (ja) 2004-03-15
ZA991550B (en) 1999-08-26
DE69904442D1 (en) 2003-01-23
CA2320180C (en) 2005-06-07
PT1056716E (pt) 2003-04-30
ES2188134T3 (es) 2003-06-16

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