DK1049672T3 - Azetidincarboxamid-derivater til behandling af CNS-lidelser - Google Patents
Azetidincarboxamid-derivater til behandling af CNS-lidelserInfo
- Publication number
- DK1049672T3 DK1049672T3 DK99902658T DK99902658T DK1049672T3 DK 1049672 T3 DK1049672 T3 DK 1049672T3 DK 99902658 T DK99902658 T DK 99902658T DK 99902658 T DK99902658 T DK 99902658T DK 1049672 T3 DK1049672 T3 DK 1049672T3
- Authority
- DK
- Denmark
- Prior art keywords
- treatment
- cns disorders
- carboxamide derivatives
- azetidine carboxamide
- azetidine
- Prior art date
Links
- 208000015114 central nervous system disease Diseases 0.000 title abstract 2
- 238000011282 treatment Methods 0.000 title abstract 2
- PVXOUGHWLCBJOW-UHFFFAOYSA-N azetidine-1-carboxamide Chemical class NC(=O)N1CCC1 PVXOUGHWLCBJOW-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000003118 aryl group Chemical group 0.000 abstract 2
- 208000019901 Anxiety disease Diseases 0.000 abstract 1
- 230000036506 anxiety Effects 0.000 abstract 1
- 206010015037 epilepsy Diseases 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/04—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Neurology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Addiction (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Anesthesiology (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9801500.1A GB9801500D0 (en) | 1998-01-23 | 1998-01-23 | Chemical compounds - II |
| GBGB9824457.7A GB9824457D0 (en) | 1998-11-06 | 1998-11-06 | Chemical compounds II |
| PCT/GB1999/000219 WO1999037612A1 (en) | 1998-01-23 | 1999-01-22 | Azetidinecarboxamide derivatives for treating cns disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1049672T3 true DK1049672T3 (da) | 2004-01-19 |
Family
ID=26313010
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK99902658T DK1049672T3 (da) | 1998-01-23 | 1999-01-22 | Azetidincarboxamid-derivater til behandling af CNS-lidelser |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US6403574B1 (enExample) |
| EP (1) | EP1049672B1 (enExample) |
| JP (1) | JP4542263B2 (enExample) |
| AT (1) | ATE250027T1 (enExample) |
| AU (1) | AU2287499A (enExample) |
| DE (1) | DE69911373T2 (enExample) |
| DK (1) | DK1049672T3 (enExample) |
| ES (1) | ES2207171T3 (enExample) |
| PT (1) | PT1049672E (enExample) |
| WO (1) | WO1999037612A1 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9917386D0 (en) * | 1999-07-23 | 1999-09-22 | Cerebrus Ltd | Chemical compounds-II |
| AU2004234125A1 (en) * | 2003-05-01 | 2004-11-11 | Vernalis Research Limited | Azetidinecarboxamide derivatives and their use in the treatment of CB1 receptor mediated disorders |
| US20060276452A1 (en) * | 2003-05-01 | 2006-12-07 | Vernalis Research Limited | Use of azetidinecarboxamide derivatives in therapy |
| EP1618105A1 (en) * | 2003-05-01 | 2006-01-25 | Vernalis Research Limited | Azetidinecarboxamide derivatives and their use in the treatment of cb1 receptor mediated disorders |
| US11141404B1 (en) * | 2020-11-18 | 2021-10-12 | Anebulo Pharmaceuticals, Inc. | Formulations and methods for treating acute cannabinoid overdose |
| US11795146B2 (en) | 2021-10-11 | 2023-10-24 | Anebulo Pharmaceuticals, Inc. | Crystalline forms of a cannabinoid receptor type 1 (CB1) modulator and methods of use and preparation thereof |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB872447A (en) | 1958-12-23 | 1961-07-12 | Lepetit Spa | 1-carbamyl-3-substituted azetidines |
| US4226861A (en) | 1978-04-18 | 1980-10-07 | A. H. Robins Company, Inc. | N-Lower-alkyl 3-phenoxy-1-azetidinecarboxamides |
| IL68699A (en) * | 1982-08-19 | 1986-08-31 | Robins Co Inc A H | 3-phenoxy-1-azetidine-carboxamides,their preparation and pharmaceutical compositions containing them |
| US4505907A (en) | 1982-09-02 | 1985-03-19 | A. H. Robins Company, Inc. | N-Formyl and N-hydroxymethyl-3-phenoxy-1-azetidinecarboxamides |
| IE58943B1 (en) * | 1985-02-28 | 1993-12-01 | Robins Co Inc A H | 3-Aryloxy-azetidine-carboxamides |
| US4956359A (en) * | 1985-02-28 | 1990-09-11 | A. H. Robins Company, Inc. | 3-aryloxy and 3-arylthioazetidinecarboxamides as anticonvulsants and antiepileptics |
-
1999
- 1999-01-22 US US09/600,628 patent/US6403574B1/en not_active Expired - Lifetime
- 1999-01-22 WO PCT/GB1999/000219 patent/WO1999037612A1/en not_active Ceased
- 1999-01-22 AU AU22874/99A patent/AU2287499A/en not_active Abandoned
- 1999-01-22 EP EP99902658A patent/EP1049672B1/en not_active Expired - Lifetime
- 1999-01-22 AT AT99902658T patent/ATE250027T1/de not_active IP Right Cessation
- 1999-01-22 ES ES99902658T patent/ES2207171T3/es not_active Expired - Lifetime
- 1999-01-22 DK DK99902658T patent/DK1049672T3/da active
- 1999-01-22 JP JP2000528536A patent/JP4542263B2/ja not_active Expired - Lifetime
- 1999-01-22 DE DE69911373T patent/DE69911373T2/de not_active Expired - Lifetime
- 1999-01-22 PT PT99902658T patent/PT1049672E/pt unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP4542263B2 (ja) | 2010-09-08 |
| DE69911373D1 (de) | 2003-10-23 |
| PT1049672E (pt) | 2004-02-27 |
| ES2207171T3 (es) | 2004-05-16 |
| EP1049672A1 (en) | 2000-11-08 |
| WO1999037612A1 (en) | 1999-07-29 |
| ATE250027T1 (de) | 2003-10-15 |
| AU2287499A (en) | 1999-08-09 |
| US6403574B1 (en) | 2002-06-11 |
| JP2002501045A (ja) | 2002-01-15 |
| DE69911373T2 (de) | 2004-07-01 |
| EP1049672B1 (en) | 2003-09-17 |
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