DK0981549T4 - Anvendelse af et inhiberende stof til forbedring af regenereringen af neutroner - Google Patents
Anvendelse af et inhiberende stof til forbedring af regenereringen af neutronerInfo
- Publication number
- DK0981549T4 DK0981549T4 DK98924307T DK98924307T DK0981549T4 DK 0981549 T4 DK0981549 T4 DK 0981549T4 DK 98924307 T DK98924307 T DK 98924307T DK 98924307 T DK98924307 T DK 98924307T DK 0981549 T4 DK0981549 T4 DK 0981549T4
- Authority
- DK
- Denmark
- Prior art keywords
- regeneration
- neutrons
- improve
- inhibitory agent
- neuronal
- Prior art date
Links
- 230000002401 inhibitory effect Effects 0.000 title 1
- 230000008929 regeneration Effects 0.000 title 1
- 238000011069 regeneration method Methods 0.000 title 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 230000005764 inhibitory process Effects 0.000 abstract 1
- 230000003902 lesion Effects 0.000 abstract 1
- 239000012528 membrane Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000001537 neural effect Effects 0.000 abstract 1
- 230000009689 neuronal regeneration Effects 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
- A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/164—Amides, e.g. hydroxamic acids of a carboxylic acid with an aminoalcohol, e.g. ceramides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/194—Carboxylic acids, e.g. valproic acid having two or more carboxyl groups, e.g. succinic, maleic or phthalic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/275—Nitriles; Isonitriles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/401—Proline; Derivatives thereof, e.g. captopril
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/4015—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having oxo groups directly attached to the heterocyclic ring, e.g. piracetam, ethosuximide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4402—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 2, e.g. pheniramine, bisacodyl
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Compounds Of Unknown Constitution (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Medicines Containing Plant Substances (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP97107846A EP0878480A1 (de) | 1997-05-14 | 1997-05-14 | Verfahren zur Förderung der Nerven-Regenerierung |
PCT/EP1998/002808 WO1998051708A1 (en) | 1997-05-14 | 1998-05-13 | A method for the improvement of neuronal regeneration |
Publications (2)
Publication Number | Publication Date |
---|---|
DK0981549T3 DK0981549T3 (da) | 2003-02-10 |
DK0981549T4 true DK0981549T4 (da) | 2007-10-29 |
Family
ID=8226794
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK98924307T DK0981549T4 (da) | 1997-05-14 | 1998-05-13 | Anvendelse af et inhiberende stof til forbedring af regenereringen af neutroner |
Country Status (8)
Country | Link |
---|---|
US (3) | US20020115598A1 (de) |
EP (2) | EP0878480A1 (de) |
AT (1) | ATE224915T1 (de) |
AU (1) | AU7654298A (de) |
DE (1) | DE69808281T3 (de) |
DK (1) | DK0981549T4 (de) |
ES (1) | ES2180175T5 (de) |
WO (1) | WO1998051708A1 (de) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0878480A1 (de) * | 1997-05-14 | 1998-11-18 | H.W. Prof. Dr. Müller | Verfahren zur Förderung der Nerven-Regenerierung |
US6200974B1 (en) | 1997-10-24 | 2001-03-13 | Zeneca Limited | Phenanthroline derivatives |
CN101664409A (zh) * | 2001-12-06 | 2010-03-10 | 法布罗根股份有限公司 | 低氧诱导因子(HIF)α的稳定化 |
CN100522946C (zh) * | 2001-12-06 | 2009-08-05 | 法布罗根股份有限公司 | 低氧诱导因子(HIF)α的稳定化 |
US7618940B2 (en) * | 2002-12-06 | 2009-11-17 | Fibrogen, Inc. | Fat regulation |
US8124582B2 (en) * | 2002-12-06 | 2012-02-28 | Fibrogen, Inc. | Treatment of diabetes |
DE10314082A1 (de) * | 2003-03-28 | 2004-10-21 | Mcs Micro Carrier Systems Gmbh | Biodegradierbares injizierbares Implantat |
KR20080044845A (ko) * | 2005-09-02 | 2008-05-21 | 노이락소 바이오파르마슈티컬즈 게엠베하 | 철 킬레이트제를 포함하는 약학적 조성물 |
WO2007048846A1 (de) * | 2005-10-27 | 2007-05-03 | Neuraxo Biopharmaceuticals Gmbh | Verwendung von eisen chelatisierenden verbindungen, zyklisches adenosinmonophosphat erhöhende verbindungen oder kombinationen davon zur behandlung von axonalen läsionen im zns |
EP2000134A1 (de) * | 2007-06-06 | 2008-12-10 | Neuraxo Biopharmaceuticals GmbH | Verwendung einer Substanz zur Behandlung von Verletzungen des peripheren Nervensystems |
US9649381B2 (en) | 2013-11-06 | 2017-05-16 | Wayne State University | Transporter protein-coupled nanodevices for targeted drug delivery |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4214000A (en) † | 1978-10-30 | 1980-07-22 | Johnson & Johnson | Zinc salt of all-trans-retinoic acid for the treatment of acne |
DE3002989A1 (de) | 1980-01-29 | 1981-07-30 | Hoechst Ag, 6000 Frankfurt | Hydroxyphenyl-thiazol, -thiazolin und -thiazolidin-carbonsaeuren, verfahren zu ihrer herstellung und ihre verwendung zur beeinflussung des kollagenstoffwechsels |
CA1251729A (en) * | 1982-05-19 | 1989-03-28 | Steffen Gay | In vitro diagnostic methods using monoclonal antibodies against connective tissue proteins |
DE3432094A1 (de) | 1984-08-31 | 1986-03-06 | Hoechst Ag, 6230 Frankfurt | Ester der pyridin-2,4- und -2,5- dicarbonsaeure als arzneimittel zur inhibierung der prolin- und lysinhydroxylase |
US5021404A (en) † | 1988-04-20 | 1991-06-04 | The Children's Medical Center Corporation | Angiostatic collagen modulators |
AU3943793A (en) * | 1992-04-01 | 1993-11-08 | Whittier Institute For Diabetes And Endocrinology, The | Methods of inhibiting or enhancing scar formation in the CNS |
JPH06103773A (ja) † | 1992-09-16 | 1994-04-15 | Hitachi Ltd | 半導体記憶装置 |
CA2117889A1 (en) * | 1993-02-11 | 1994-08-18 | Martin E. Schwab | A combination of neurotrophin and antibody directed toward myelin-associated neurite growth inhibitory protein promotes central nervous system regeneration |
JPH09503790A (ja) * | 1993-10-15 | 1997-04-15 | トーマス ジェファーソン ユニバーシティ | 核原発ガン遺伝子に向けられたアンチセンス化合物による細胞外マトリクス合成の阻害 |
WO1995013291A1 (en) * | 1993-11-08 | 1995-05-18 | New York University | Neuron-glia cell adhesion molecule, ng-cam, in treatment of nerve damage |
US5567609A (en) * | 1994-06-30 | 1996-10-22 | University Of Kansas Medical Center | Use of isolated domains of type IV collagen to modify cell and tissue interactions |
EP0878480A1 (de) * | 1997-05-14 | 1998-11-18 | H.W. Prof. Dr. Müller | Verfahren zur Förderung der Nerven-Regenerierung |
-
1997
- 1997-05-14 EP EP97107846A patent/EP0878480A1/de not_active Withdrawn
-
1998
- 1998-03-13 US US09/423,622 patent/US20020115598A1/en not_active Abandoned
- 1998-05-13 AT AT98924307T patent/ATE224915T1/de not_active IP Right Cessation
- 1998-05-13 EP EP98924307A patent/EP0981549B9/de not_active Expired - Lifetime
- 1998-05-13 ES ES98924307T patent/ES2180175T5/es not_active Expired - Lifetime
- 1998-05-13 WO PCT/EP1998/002808 patent/WO1998051708A1/en active IP Right Grant
- 1998-05-13 AU AU76542/98A patent/AU7654298A/en not_active Abandoned
- 1998-05-13 DK DK98924307T patent/DK0981549T4/da active
- 1998-05-13 DE DE69808281T patent/DE69808281T3/de not_active Expired - Lifetime
-
2004
- 2004-05-04 US US10/837,762 patent/US7208153B2/en not_active Expired - Fee Related
-
2007
- 2007-03-16 US US11/723,191 patent/US20070231330A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
US7208153B2 (en) | 2007-04-24 |
DE69808281T2 (de) | 2003-01-16 |
AU7654298A (en) | 1998-12-08 |
DK0981549T3 (da) | 2003-02-10 |
DE69808281D1 (de) | 2002-10-31 |
DE69808281T3 (de) | 2008-01-24 |
US20020115598A1 (en) | 2002-08-22 |
US20070231330A1 (en) | 2007-10-04 |
WO1998051708A1 (en) | 1998-11-19 |
EP0878480A1 (de) | 1998-11-18 |
ATE224915T1 (de) | 2002-10-15 |
EP0981549A1 (de) | 2000-03-01 |
EP0981549B1 (de) | 2002-09-25 |
EP0981549B2 (de) | 2007-06-27 |
US20050118177A1 (en) | 2005-06-02 |
EP0981549B9 (de) | 2008-02-27 |
ES2180175T5 (es) | 2008-02-01 |
ES2180175T3 (es) | 2003-02-01 |
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