DK0970105T3 - Fremgangsmåde til fremstilling af carboxamido-4-azasteroider - Google Patents

Fremgangsmåde til fremstilling af carboxamido-4-azasteroider

Info

Publication number
DK0970105T3
DK0970105T3 DK98966861T DK98966861T DK0970105T3 DK 0970105 T3 DK0970105 T3 DK 0970105T3 DK 98966861 T DK98966861 T DK 98966861T DK 98966861 T DK98966861 T DK 98966861T DK 0970105 T3 DK0970105 T3 DK 0970105T3
Authority
DK
Denmark
Prior art keywords
pct
sec
azasteroids
carboxamido
date
Prior art date
Application number
DK98966861T
Other languages
Danish (da)
English (en)
Inventor
Achille Panzeri
Anello Matteo D
Antonio Longo
Marcella Nesi
Original Assignee
Pharmacia Italia Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia Italia Spa filed Critical Pharmacia Italia Spa
Application granted granted Critical
Publication of DK0970105T3 publication Critical patent/DK0970105T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J73/00—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J73/00—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms
    • C07J73/001—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms by one hetero atom
    • C07J73/005—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms by one hetero atom by nitrogen as hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones

Landscapes

  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Steroid Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DK98966861T 1997-12-31 1998-12-17 Fremgangsmåde til fremstilling af carboxamido-4-azasteroider DK0970105T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9727522.6A GB9727522D0 (en) 1997-12-31 1997-12-31 Process for preparing carboxamido-4-azasteroids
PCT/EP1998/008527 WO1999035161A1 (en) 1997-12-31 1998-12-17 Process for preparing carboxamido-4-azasteroids

Publications (1)

Publication Number Publication Date
DK0970105T3 true DK0970105T3 (da) 2002-05-27

Family

ID=10824341

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98966861T DK0970105T3 (da) 1997-12-31 1998-12-17 Fremgangsmåde til fremstilling af carboxamido-4-azasteroider

Country Status (19)

Country Link
US (2) US6121449A (de)
EP (1) EP0970105B1 (de)
JP (1) JP2001515518A (de)
KR (1) KR20000075845A (de)
CN (1) CN1248263A (de)
AT (1) ATE213741T1 (de)
AU (1) AU753602B2 (de)
CA (1) CA2278487A1 (de)
DE (1) DE69803979T2 (de)
DK (1) DK0970105T3 (de)
ES (1) ES2173675T3 (de)
GB (1) GB9727522D0 (de)
HU (1) HUP0001444A3 (de)
NO (1) NO312195B1 (de)
PT (1) PT970105E (de)
RU (1) RU2198176C2 (de)
TW (1) TW442491B (de)
WO (1) WO1999035161A1 (de)
ZA (1) ZA9811950B (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE39056E1 (en) 1995-09-15 2006-04-04 Merck & Co, Inc. 4-Azasteroids for treatment of hyperandrogenic conditions
US6645974B2 (en) 2001-07-31 2003-11-11 Merck & Co., Inc. Androgen receptor modulators and methods for use thereof
AU2004255749B2 (en) 2003-06-30 2008-12-18 Merck Sharp & Dohme Corp. 17-acetamido-4-azasteroid derivatives as androgen receptor modulators
CN1816370A (zh) * 2003-06-30 2006-08-09 麦克公司 用作雄激素受体调节剂的17－乙酰氨基－4－氮杂甾族化合物衍生物
AU2004255200A1 (en) * 2003-06-30 2005-01-20 Merck & Co., Inc. 17-acetamido-4-azasteroid derivatives as androgen receptor modulators
CN100528168C (zh) * 2003-06-30 2009-08-19 麦克公司 作为雄激素受体调节剂的17-乙酰氨基-4-氮杂甾类衍生物
EP1670483A4 (de) * 2003-09-10 2010-02-17 Merck & Co Inc 17-heterocyclische 4-azasteroid-derivate als androgen-rezeptormodulatoren

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5237061A (en) * 1988-10-31 1993-08-17 Merck & Co., Inc. Methods of synthesizing benign prostatic hypertropic agents and their intermediates
GB9002922D0 (en) * 1990-02-09 1990-04-04 Erba Carlo Spa 17 beta-substituted-4-aza-5 alpha-androstan-3-one derivatives and process for their preparation
GB9115676D0 (en) * 1991-07-19 1991-09-04 Erba Carlo Spa Process for the preparation of 17 beta substituted-4-aza-5 alpha-androstan-3-one derivatives
GB9216284D0 (en) * 1992-07-31 1992-09-16 Erba Carlo Spa Fluorinated 17beta-substituted 4-aza-5alpha-androstane-3-one derivatives
GB9216329D0 (en) * 1992-07-31 1992-09-16 Erba Carlo Spa 17beta-substituted 4-aza-5alpha-androstan-3-one derivatives
GB9415178D0 (en) * 1994-07-28 1994-09-21 Erba Carlo Spa 4-azasteroids with side-chain fluoroketones

Also Published As

Publication number Publication date
US6121449A (en) 2000-09-19
HUP0001444A3 (en) 2001-03-28
DE69803979T2 (de) 2003-02-06
EP0970105A1 (de) 2000-01-12
AU2514699A (en) 1999-07-26
AU753602B2 (en) 2002-10-24
JP2001515518A (ja) 2001-09-18
PT970105E (pt) 2002-07-31
DE69803979D1 (de) 2002-04-04
HUP0001444A2 (hu) 2000-11-28
ZA9811950B (en) 1999-06-30
EP0970105B1 (de) 2002-02-27
NO994199L (no) 1999-10-29
CN1248263A (zh) 2000-03-22
NO994199D0 (no) 1999-08-30
ES2173675T3 (es) 2002-10-16
NO312195B1 (no) 2002-04-08
CA2278487A1 (en) 1999-07-15
KR20000075845A (ko) 2000-12-26
TW442491B (en) 2001-06-23
ATE213741T1 (de) 2002-03-15
US6284887B1 (en) 2001-09-04
WO1999035161A1 (en) 1999-07-15
GB9727522D0 (en) 1998-02-25
RU2198176C2 (ru) 2003-02-10

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