DK0958371T3 - Cytopatiske vira til behandling og forebyggelse af neoplasi - Google Patents
Cytopatiske vira til behandling og forebyggelse af neoplasiInfo
- Publication number
- DK0958371T3 DK0958371T3 DK97951519T DK97951519T DK0958371T3 DK 0958371 T3 DK0958371 T3 DK 0958371T3 DK 97951519 T DK97951519 T DK 97951519T DK 97951519 T DK97951519 T DK 97951519T DK 0958371 T3 DK0958371 T3 DK 0958371T3
- Authority
- DK
- Denmark
- Prior art keywords
- replication phenotype
- cells
- neoplastic cells
- viral
- neoplastic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10322—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10341—Use of virus, viral particle or viral elements as a vector
- C12N2710/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10361—Methods of inactivation or attenuation
- C12N2710/10362—Methods of inactivation or attenuation by genetic engineering
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Virology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Plant Pathology (AREA)
- Gastroenterology & Hepatology (AREA)
- Physics & Mathematics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US3461596P | 1996-12-31 | 1996-12-31 | |
PCT/US1997/022036 WO1998029555A2 (en) | 1996-12-31 | 1997-12-10 | Cytopathic viruses for therapy and prophylaxis of neoplasia |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0958371T3 true DK0958371T3 (da) | 2004-04-13 |
Family
ID=21877522
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK97951519T DK0958371T3 (da) | 1996-12-31 | 1997-12-10 | Cytopatiske vira til behandling og forebyggelse af neoplasi |
Country Status (11)
Country | Link |
---|---|
US (1) | US6080578A (da) |
EP (1) | EP0958371B1 (da) |
JP (1) | JP4225577B2 (da) |
AT (1) | ATE256195T1 (da) |
AU (1) | AU723604B2 (da) |
CA (1) | CA2273825C (da) |
DE (1) | DE69726759T2 (da) |
DK (1) | DK0958371T3 (da) |
ES (1) | ES2212815T3 (da) |
PT (1) | PT958371E (da) |
WO (1) | WO1998029555A2 (da) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5998205A (en) | 1994-11-28 | 1999-12-07 | Genetic Therapy, Inc. | Vectors for tissue-specific replication |
US6638762B1 (en) | 1994-11-28 | 2003-10-28 | Genetic Therapy, Inc. | Tissue-vectors specific replication and gene expression |
US6326356B1 (en) | 1996-10-18 | 2001-12-04 | Board Of Regents, The University Of Texas System | Suppression of neu overexpression using a mini-E1A gene |
US20020068049A1 (en) * | 1998-09-10 | 2002-06-06 | Henderson Daniel R. | Tissue specific adenoviral vectors |
JP2002515442A (ja) * | 1998-05-15 | 2002-05-28 | オニックス ファーマシューティカルズ,インコーポレイティド | 癌を処置するためのアデノウィルス−化学治療剤のコンビネーション |
US7691370B2 (en) | 1998-10-15 | 2010-04-06 | Canji, Inc. | Selectivity replicating viral vector |
US6764674B1 (en) * | 1999-01-28 | 2004-07-20 | Onyx Pharmaceuticals Inc. | Adenovirus E1B shuttle vectors |
US20040175362A1 (en) | 1999-05-12 | 2004-09-09 | Curiel David T. | Infectivity-enhanced conditionally-replicative adenovirus and uses thereof |
US7048920B2 (en) | 2000-03-24 | 2006-05-23 | Cell Genesys, Inc. | Recombinant oncolytic adenovirus for human melanoma |
US6911200B2 (en) | 2000-03-24 | 2005-06-28 | Cell Genesys, Inc. | Methods of treating neoplasia with combination of target-cell specific adenovirus, chemotherapy and radiation |
JP2004505633A (ja) * | 2000-08-03 | 2004-02-26 | オニックス ファーマシューティカルズ,インコーポレイティド | アデノウイルスe1b−55k単一アミノ酸変異体および使用方法 |
US20040101825A1 (en) * | 2001-09-26 | 2004-05-27 | Van Meir Erwin G. | Viruses targeted to hypoxic cells and tissues |
US7285414B2 (en) * | 2000-09-26 | 2007-10-23 | Emory University | Viruses targeted to hypoxic cells and tissues |
US20030138405A1 (en) * | 2001-04-17 | 2003-07-24 | Juan Fueyo | Conditionally replicative adenovirus to target the Rb and Rb-related pathways |
AU2002346084B2 (en) * | 2001-07-23 | 2006-11-16 | Onyx Pharmaceuticals, Inc. | Viral mutants that selectively replicate in targeted human cancer cells |
JP4354814B2 (ja) * | 2001-09-29 | 2009-10-28 | ヨンセイ ユニバーシティ | 改善された疾患治療効果を有する組換えアデノウィルス及びそれを含む薬剤学的組成物 |
US20060147420A1 (en) | 2004-03-10 | 2006-07-06 | Juan Fueyo | Oncolytic adenovirus armed with therapeutic genes |
AU2003242585A1 (en) | 2002-05-27 | 2003-12-12 | Per Sonne Holm | Novel use of adenoviruses and nucleic acids coding therefor |
US7364727B2 (en) | 2002-07-22 | 2008-04-29 | Cell Genesys, Inc. | Metastatic colon cancer specific promoter and uses thereof |
WO2004042025A2 (en) | 2002-11-01 | 2004-05-21 | Cell Genesys, Inc. | Cell-specific adenovirus vector comprising ebv-specific promoter |
US20040202663A1 (en) * | 2003-01-28 | 2004-10-14 | Shanghai Sunway Biotech Co., Ltd. | Therapy for primary and metastatic cancers |
EP1646717A4 (en) * | 2003-07-18 | 2006-12-20 | Onyx Pharma Inc | ADENOVIRAL VECTORS OF SUB-GROUP B FOR THE TREATMENT OF DISEASES |
CA2546178A1 (en) | 2003-11-14 | 2005-06-09 | Per Sonne Holm | New use of adenovirus and nucleic acids coding therefor |
EP2806883B1 (en) | 2012-01-25 | 2019-04-24 | DNAtrix, Inc. | Biomarkers and combination therapies using oncolytic virus and immunomodulation |
SG10201913795TA (en) | 2012-02-02 | 2020-03-30 | Univ Texas | Adenoviruses expressing heterologous tumor-associated antigens |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5801029A (en) * | 1993-02-16 | 1998-09-01 | Onyx Pharmaceuticals, Inc. | Cytopathic viruses for therapy and prophylaxis of neoplasia |
JP3556666B2 (ja) * | 1993-02-16 | 2004-08-18 | オニックス ファーマシューティカルズ,インコーポレイテイド | 新形成の治療及び予防のための細胞障害ウイルス |
-
1997
- 1997-12-08 US US08/986,331 patent/US6080578A/en not_active Expired - Fee Related
- 1997-12-10 CA CA2273825A patent/CA2273825C/en not_active Expired - Fee Related
- 1997-12-10 AU AU55145/98A patent/AU723604B2/en not_active Ceased
- 1997-12-10 PT PT97951519T patent/PT958371E/pt unknown
- 1997-12-10 JP JP53001898A patent/JP4225577B2/ja not_active Expired - Fee Related
- 1997-12-10 AT AT97951519T patent/ATE256195T1/de active
- 1997-12-10 DK DK97951519T patent/DK0958371T3/da active
- 1997-12-10 ES ES97951519T patent/ES2212815T3/es not_active Expired - Lifetime
- 1997-12-10 DE DE1997626759 patent/DE69726759T2/de not_active Expired - Lifetime
- 1997-12-10 WO PCT/US1997/022036 patent/WO1998029555A2/en active IP Right Grant
- 1997-12-10 EP EP97951519A patent/EP0958371B1/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
JP4225577B2 (ja) | 2009-02-18 |
EP0958371A2 (en) | 1999-11-24 |
DE69726759D1 (de) | 2004-01-22 |
EP0958371B1 (en) | 2003-12-10 |
AU5514598A (en) | 1998-07-31 |
WO1998029555A2 (en) | 1998-07-09 |
CA2273825C (en) | 2011-02-08 |
DE69726759T2 (de) | 2005-01-13 |
US6080578A (en) | 2000-06-27 |
PT958371E (pt) | 2004-04-30 |
AU723604B2 (en) | 2000-08-31 |
JP2001508290A (ja) | 2001-06-26 |
ES2212815T3 (es) | 2004-08-01 |
WO1998029555A3 (en) | 1998-10-01 |
CA2273825A1 (en) | 1998-07-09 |
ATE256195T1 (de) | 2003-12-15 |
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