DK0958351T3 - Chimere målmolekyler med regulerbar aktivitet - Google Patents
Chimere målmolekyler med regulerbar aktivitetInfo
- Publication number
- DK0958351T3 DK0958351T3 DK97952131.7T DK97952131T DK0958351T3 DK 0958351 T3 DK0958351 T3 DK 0958351T3 DK 97952131 T DK97952131 T DK 97952131T DK 0958351 T3 DK0958351 T3 DK 0958351T3
- Authority
- DK
- Denmark
- Prior art keywords
- molecule
- binding molecule
- chimeric
- activity
- binding
- Prior art date
Links
- 230000000694 effects Effects 0.000 title abstract 4
- 239000012491 analyte Substances 0.000 abstract 4
- 238000000034 method Methods 0.000 abstract 2
- 230000000415 inactivating effect Effects 0.000 abstract 1
- 230000001105 regulatory effect Effects 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
- G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
- C12N9/86—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in cyclic amides, e.g. penicillinase (3.5.2)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y305/00—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5)
- C12Y305/02—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5) in cyclic amides (3.5.2)
- C12Y305/02006—Beta-lactamase (3.5.2.6)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
- C07K2319/735—Fusion polypeptide containing domain for protein-protein interaction containing a domain for self-assembly, e.g. a viral coat protein (includes phage display)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- General Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Food Science & Technology (AREA)
- Cell Biology (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Bakery Products And Manufacturing Methods Therefor (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/757,425 US6500660B1 (en) | 1996-11-27 | 1996-11-27 | Chimeric target molecules having a regulatable activity |
PCT/IB1997/001643 WO1998023731A2 (en) | 1996-11-27 | 1997-11-26 | Chimeric target molecules having a regulatable activity |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0958351T3 true DK0958351T3 (da) | 2010-03-15 |
Family
ID=25047774
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK97952131.7T DK0958351T3 (da) | 1996-11-27 | 1997-11-26 | Chimere målmolekyler med regulerbar aktivitet |
Country Status (10)
Country | Link |
---|---|
US (1) | US6500660B1 (da) |
EP (1) | EP0958351B1 (da) |
JP (1) | JP4416185B2 (da) |
AT (1) | ATE449166T1 (da) |
AU (1) | AU5571998A (da) |
DE (1) | DE69739664D1 (da) |
DK (1) | DK0958351T3 (da) |
ES (1) | ES2336634T3 (da) |
PT (1) | PT958351E (da) |
WO (1) | WO1998023731A2 (da) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1349869A4 (en) * | 2000-11-08 | 2007-12-12 | Commw Scient Ind Res Org | METHOD FOR IDENTIFYING ANTIBACTERIAL COMPOUNDS |
US7705120B2 (en) | 2001-06-21 | 2010-04-27 | Millennium Pharmaceuticals, Inc. | Compositions, kits, and methods for identification, assessment, prevention, and therapy of breast cancer |
KR100428998B1 (ko) * | 2001-09-10 | 2004-04-28 | 한국과학기술원 | 모체 단백질과는 크기와 서열이 다른 단백질의 변이집단을생산하는 방법 |
GB0209878D0 (en) * | 2002-04-30 | 2002-06-05 | Glaxosmithkline Biolog Sa | Vaccine |
EP2297207B1 (en) * | 2008-06-19 | 2018-10-03 | Prothix BV | Use of anti-factor xi antibodies for prevention or treatment of thrombus formation |
DE102022000897A1 (de) | 2022-03-15 | 2023-09-21 | Ruhr-Universität Bochum, Körperschaft des öffentlichen Rechts | Implantierbarer Biosensor |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1988002757A1 (en) * | 1986-10-17 | 1988-04-21 | Saramane Pty. Ltd.; | Hybrid proteins or polypeptides |
EP0397834B1 (en) * | 1988-10-28 | 2000-02-02 | Genentech, Inc. | Method for identifying active domains and amino acid residues in polypeptides and hormone variants |
WO1992007090A1 (en) * | 1990-10-22 | 1992-04-30 | Genentech, Inc. | Methods for modifying and detecting the effects on the interaction of modified polypeptides and target substrates |
AU4238893A (en) * | 1992-05-07 | 1993-11-29 | Regents Of The University Of California, The | Novel diphtheria toxin-based molecules |
US5674681A (en) * | 1994-12-06 | 1997-10-07 | Rothenberg; Barry E. | Methods to identify hemochromatosis |
-
1996
- 1996-11-27 US US08/757,425 patent/US6500660B1/en not_active Expired - Lifetime
-
1997
- 1997-11-26 ES ES97952131T patent/ES2336634T3/es not_active Expired - Lifetime
- 1997-11-26 AU AU55719/98A patent/AU5571998A/en not_active Abandoned
- 1997-11-26 WO PCT/IB1997/001643 patent/WO1998023731A2/en active Application Filing
- 1997-11-26 DE DE69739664T patent/DE69739664D1/de not_active Expired - Lifetime
- 1997-11-26 EP EP97952131A patent/EP0958351B1/en not_active Expired - Lifetime
- 1997-11-26 AT AT97952131T patent/ATE449166T1/de active
- 1997-11-26 DK DK97952131.7T patent/DK0958351T3/da active
- 1997-11-26 PT PT97952131T patent/PT958351E/pt unknown
- 1997-11-26 JP JP52642798A patent/JP4416185B2/ja not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
DE69739664D1 (de) | 2009-12-31 |
AU5571998A (en) | 1998-06-22 |
WO1998023731A3 (en) | 1998-11-12 |
PT958351E (pt) | 2010-02-17 |
WO1998023731A2 (en) | 1998-06-04 |
EP0958351B1 (en) | 2009-11-18 |
US6500660B1 (en) | 2002-12-31 |
ES2336634T3 (es) | 2010-04-14 |
JP2001515346A (ja) | 2001-09-18 |
JP4416185B2 (ja) | 2010-02-17 |
ATE449166T1 (de) | 2009-12-15 |
EP0958351A2 (en) | 1999-11-24 |
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