DK0948491T3 - Aminothiazolderivater egnet til fremstilling af beta-lactam-antibiotika - Google Patents

Aminothiazolderivater egnet til fremstilling af beta-lactam-antibiotika

Info

Publication number
DK0948491T3
DK0948491T3 DK97952008T DK97952008T DK0948491T3 DK 0948491 T3 DK0948491 T3 DK 0948491T3 DK 97952008 T DK97952008 T DK 97952008T DK 97952008 T DK97952008 T DK 97952008T DK 0948491 T3 DK0948491 T3 DK 0948491T3
Authority
DK
Denmark
Prior art keywords
beta
preparation
lactam antibiotics
derivatives suitable
aminothiazole derivatives
Prior art date
Application number
DK97952008T
Other languages
Danish (da)
English (en)
Inventor
Mario Leone
Maurizio Zenoni
Maurizio Serra
Mauro Filippi
Original Assignee
Ortho Mcneil Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho Mcneil Pharm Inc filed Critical Ortho Mcneil Pharm Inc
Application granted granted Critical
Publication of DK0948491T3 publication Critical patent/DK0948491T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/587—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with aliphatic hydrocarbon radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms, said aliphatic radicals being substituted in the alpha-position to the ring by a hetero atom, e.g. with m >= 0, Z being a singly or a doubly bound hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
DK97952008T 1997-10-30 1997-11-28 Aminothiazolderivater egnet til fremstilling af beta-lactam-antibiotika DK0948491T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT97MI002439A IT1295935B1 (it) 1997-10-30 1997-10-30 Derivati aminotiazolici utili nella preparazione di antibiotici b -lattamici
PCT/EP1997/006654 WO1999023082A1 (en) 1997-10-30 1997-11-28 AMINOTHIAZOLE DERIVATIVES USEFUL IN THE PREPARATION OF β-LACTAM ANTIBIOTICS

Publications (1)

Publication Number Publication Date
DK0948491T3 true DK0948491T3 (da) 2004-04-13

Family

ID=11378130

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97952008T DK0948491T3 (da) 1997-10-30 1997-11-28 Aminothiazolderivater egnet til fremstilling af beta-lactam-antibiotika

Country Status (11)

Country Link
US (1) US6255480B1 (ja)
EP (1) EP0948491B1 (ja)
JP (1) JP2001517248A (ja)
AT (1) ATE258169T1 (ja)
AU (1) AU5558198A (ja)
DE (1) DE69727315T2 (ja)
DK (1) DK0948491T3 (ja)
ES (1) ES2213229T3 (ja)
IT (1) IT1295935B1 (ja)
PT (1) PT948491E (ja)
WO (1) WO1999023082A1 (ja)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100448856C (zh) * 2006-06-26 2009-01-07 山东金城医药化工股份有限公司 一种催化合成ae-活性酯的工艺
CN103012312B (zh) * 2012-12-04 2015-05-06 山东鑫泉医药有限公司 氨噻肟酸生产废水回用的方法
CN103588790A (zh) * 2013-11-29 2014-02-19 中国科学院长春应用化学研究所 7-氨基-3-氯-3-头孢-4-羧酸-对硝基苄基酯的制备方法
CN103588789A (zh) * 2013-11-29 2014-02-19 中国科学院长春应用化学研究所 7-氨基-3-氯-3-头孢-4-羧酸的制备方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2758001A1 (de) * 1977-12-24 1979-07-12 Hoechst Ag Cephalosporinderivate und verfahren zu ihrer herstellung
US4703046A (en) * 1978-09-08 1987-10-27 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds and processes for preparation thereof
EP0037380B1 (en) 1980-03-28 1984-09-12 BIOCHEMIE Gesellschaft m.b.H. New process for the production of cephalosporin antibiotics, and novel intermediates used in such process and their production
EP0055465B1 (en) * 1980-12-31 1989-08-23 Fujisawa Pharmaceutical Co., Ltd. 7-acylaminocephalosporanic acid derivatives and processes for the preparation thereof
EP0210815A3 (en) 1985-07-25 1988-04-20 Beecham Group Plc 6-beta-(alpha-etherified oxyimino)-acylamino penicillanic-acid derivatives, their preparation and use
GB9024223D0 (en) 1990-11-07 1990-12-19 Fermentech Ltd Production of hyaluronic acid
GB9216759D0 (en) 1992-08-07 1992-09-23 Finpael Spa Process for the production of 7-amino thiazolyl cephalosporins
AT402928B (de) * 1994-12-23 1997-09-25 Biochemie Gmbh Neues verfahren zur herstellung von cefotaxim
GB9519883D0 (en) 1995-09-29 1995-11-29 Fujisawa Pharmaceutical Co New cephem compounds
MY127641A (en) 1995-10-12 2006-12-29 Essential Therapeutics Inc Cephalosporin antibiotics
IN184690B (ja) * 1996-03-18 2000-09-23 Ranbaxy Lab Ltd

Also Published As

Publication number Publication date
ITMI972439A1 (it) 1999-04-30
ATE258169T1 (de) 2004-02-15
PT948491E (pt) 2004-06-30
WO1999023082A1 (en) 1999-05-14
JP2001517248A (ja) 2001-10-02
US6255480B1 (en) 2001-07-03
EP0948491B1 (en) 2004-01-21
AU5558198A (en) 1999-05-24
ES2213229T3 (es) 2004-08-16
DE69727315D1 (de) 2004-02-26
EP0948491A1 (en) 1999-10-13
DE69727315T2 (de) 2004-11-18
IT1295935B1 (it) 1999-05-28

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