DK0927217T3 - Antiangiogene forbindelser - Google Patents

Antiangiogene forbindelser

Info

Publication number
DK0927217T3
DK0927217T3 DK97929038T DK97929038T DK0927217T3 DK 0927217 T3 DK0927217 T3 DK 0927217T3 DK 97929038 T DK97929038 T DK 97929038T DK 97929038 T DK97929038 T DK 97929038T DK 0927217 T3 DK0927217 T3 DK 0927217T3
Authority
DK
Denmark
Prior art keywords
dendrimer
anionic
cationic
linked
linear
Prior art date
Application number
DK97929038T
Other languages
Danish (da)
English (en)
Inventor
Barry Ross Matthews
George Holan
Original Assignee
Starpharma Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Starpharma Pty Ltd filed Critical Starpharma Pty Ltd
Application granted granted Critical
Publication of DK0927217T3 publication Critical patent/DK0927217T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G69/00—Macromolecular compounds obtained by reactions forming a carboxylic amide link in the main chain of the macromolecule
    • C08G69/02—Polyamides derived from amino-carboxylic acids or from polyamines and polycarboxylic acids
    • C08G69/36—Polyamides derived from amino-carboxylic acids or from polyamines and polycarboxylic acids derived from amino acids, polyamines and polycarboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G83/00—Macromolecular compounds not provided for in groups C08G2/00 - C08G81/00
    • C08G83/002—Dendritic macromolecules
    • C08G83/003—Dendrimers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/795—Polymers containing sulfur
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G69/00—Macromolecular compounds obtained by reactions forming a carboxylic amide link in the main chain of the macromolecule
    • C08G69/02—Polyamides derived from amino-carboxylic acids or from polyamines and polycarboxylic acids
    • C08G69/08—Polyamides derived from amino-carboxylic acids or from polyamines and polycarboxylic acids derived from amino-carboxylic acids
    • C08G69/10—Alpha-amino-carboxylic acids
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S424/00—Drug, bio-affecting and body treating compositions
    • Y10S424/16—Dendrimers and dendritic polymers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Polymers & Plastics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Vascular Medicine (AREA)
  • Oncology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Optical Fibers, Optical Fiber Cores, And Optical Fiber Bundles (AREA)
  • Liquid Crystal Substances (AREA)
  • Chemical And Physical Treatments For Wood And The Like (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Polyamides (AREA)
DK97929038T 1996-07-17 1997-07-17 Antiangiogene forbindelser DK0927217T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AUPO1044A AUPO104496A0 (en) 1996-07-17 1996-07-17 Angiogenic inhibitory compounds

Publications (1)

Publication Number Publication Date
DK0927217T3 true DK0927217T3 (da) 2006-08-14

Family

ID=3795360

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97929038T DK0927217T3 (da) 1996-07-17 1997-07-17 Antiangiogene forbindelser

Country Status (15)

Country Link
US (1) US6426067B1 (enExample)
EP (1) EP0927217B1 (enExample)
JP (1) JP2000516211A (enExample)
KR (1) KR100564714B1 (enExample)
CN (1) CN1161128C (enExample)
AT (1) ATE325154T1 (enExample)
AU (1) AUPO104496A0 (enExample)
BR (1) BR9710375A (enExample)
CA (1) CA2262862C (enExample)
DE (1) DE69735810T2 (enExample)
DK (1) DK0927217T3 (enExample)
ES (1) ES2260796T3 (enExample)
NZ (1) NZ333488A (enExample)
PT (1) PT927217E (enExample)
WO (1) WO1998003573A1 (enExample)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7018637B2 (en) * 1998-02-23 2006-03-28 Aventis Pasteur, Inc Multi-oligosaccharide glycoconjugate bacterial meningitis vaccines
FR2781485B1 (fr) 1998-07-21 2003-08-08 Denis Barritault Polymeres biocompatibles leur procede de preparation et les compositions les contenant
AUPP584298A0 (en) * 1998-09-14 1998-10-08 Starpharma Limited Antimicrobial and antiparasitic agents
GB0001481D0 (en) * 2000-01-21 2000-03-15 Theryte Ltd System for delivering a medicament
WO2001072699A1 (en) * 2000-03-27 2001-10-04 The Scripps Research Institute Inhibition of angiogenesis and tumor growth
KR100413532B1 (ko) * 2001-02-14 2003-12-31 학교법인 포항공과대학교 폴리아민이 말단에 치환된 덴드리머 및 그 제조방법
AUPR412801A0 (en) 2001-03-30 2001-05-03 Starpharma Limited Agent for the prevention and treatment of sexually transmitted disease s - I
AUPR412901A0 (en) * 2001-03-30 2001-05-03 Starpharma Limited Agents for the prevention and treatment of sexually transmitted disease s - II
US20030135195A1 (en) * 2002-01-16 2003-07-17 Oscar Jimenez Highly lubricious hydrophilic coating utilizing dendrimers
US20030180250A1 (en) * 2002-03-22 2003-09-25 Council Of Scientific And Industrial Research Compositions and complexes containing a macromolecular compound as potential anti-inflammatory agents
CA2523413A1 (en) * 2003-04-25 2004-11-11 The Penn State Research Foundation Method and system for systemic delivery of growth arresting, lipid-derived bioactive compounds
CN102653515A (zh) * 2004-06-15 2012-09-05 宝利麦迪克斯股份有限公司 聚阳离子化合物及其用途
FR2876916B1 (fr) * 2004-10-25 2007-01-05 Midi Pyrenees Incubateur Produit implantable de surface fonctionnalisee au moyen de dendrimeres a terminaisons anioniques
KR100667171B1 (ko) 2005-05-10 2007-01-12 서애희 세포내 물질전달용 ｐａｍａｍ 유도체 및 이를 이용한세포내 원하는 물질의 전달방법
GR1005807B (el) * 2005-07-13 2008-02-06 Αρισταρχος Παπαγιανναρος Ρυθμιστικο λιποσωμιακο συστημα ελεγχομενης αποδεσμευσης: νεα φαρμακοτεχνικη μορφη για εγκλωβισμο αντικαρκινικων φαρμακων με βαση την τεχνολογια των λιποσωματων και των δενδριμερων
WO2007045010A1 (en) * 2005-10-21 2007-04-26 Starpharma Pty Limited Inhibitory compounds
DE102005056592A1 (de) * 2005-11-25 2007-05-31 Basf Ag Herstellung und Verwendung von hochfunktionellen, hoch-oder hyperverzweigten Polylysinen
JP5989294B2 (ja) * 2006-01-20 2016-09-07 スターファーマ・プロプライエタリー・リミテッドＳｔａｒｐｈａｒｍａ Ｐｔｙ Ｌｔｄ 修飾高分子
CN101405010B (zh) 2006-03-22 2013-03-06 星药股份有限公司 避孕组合物
DE102006036326A1 (de) * 2006-08-03 2008-02-07 Charité - Universitätsmedizin Berlin Dendritische Polyglycerolsulfate und -sulfonate und deren Verwendung bei entzündlichen Erkrankungen
US20080311177A1 (en) 2007-06-14 2008-12-18 Massachusetts Institute Of Technology Self Assembled Films for Protein and Drug Delivery Applications
US8658148B2 (en) 2007-06-22 2014-02-25 Genzyme Corporation Chemically modified dendrimers
US10106565B2 (en) 2008-08-01 2018-10-23 Centre National De La Recherche Scientifique Phosphorylated dendrimers as antiinflammatory drugs
WO2010013086A1 (en) * 2008-08-01 2010-02-04 Centre National De La Recherche Scientifique Phosphorylated dendrimers as antiinflammatory drugs
WO2010021973A2 (en) 2008-08-17 2010-02-25 Massachusetts Institute Of Technology Controlled delivery of bioactive agents from decomposable films
CN107669698A (zh) * 2011-05-16 2018-02-09 星法马私人有限公司 治疗或预防细菌性阴道病的方法
WO2013163234A1 (en) 2012-04-23 2013-10-31 Massachusetts Institute Of Technology Stable layer-by-layer coated particles
WO2014134029A1 (en) 2013-02-26 2014-09-04 Massachusetts Institute Of Technology Nucleic acid particles, methods and use thereof
WO2014150074A1 (en) 2013-03-15 2014-09-25 Massachusetts Institute Of Technology Compositions and methods for nucleic acid delivery
US20160222173A1 (en) * 2015-01-26 2016-08-04 National Chiao Tung University Dendrimer, dendrimer having functional group and antibody
DE102017002810A1 (de) 2017-03-22 2018-09-27 Reinhard Brossmer Sialinsäurederivate mit C-C Dreifachbindung und deren Herstellung
WO2019089567A1 (en) 2017-10-30 2019-05-09 Massachusetts Institute Of Technology Layer-by-layer nanoparticles for cytokine therapy in cancer treatment
WO2021002984A1 (en) 2019-05-30 2021-01-07 Massachusetts Institute Of Technology Peptide nucleic acid functionalized hydrogel microneedles for sampling and detection of interstitial fluid nucleic acids

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2182667B1 (enExample) * 1972-05-03 1978-03-03 Rhone Poulenc Ind
US4289872A (en) * 1979-04-06 1981-09-15 Allied Corporation Macromolecular highly branched homogeneous compound based on lysine units
US4410688A (en) 1981-04-29 1983-10-18 Allied Corporation Macromolecular highly branched homogeneous compound
HU187669B (en) * 1982-03-31 1986-02-28 Richter Gedeon Vegyeszet Process for producing new copolymeres and salts
US4507466A (en) 1983-01-07 1985-03-26 The Dow Chemical Corporation Dense star polymers having core, core branches, terminal groups
US4558120A (en) 1983-01-07 1985-12-10 The Dow Chemical Company Dense star polymer
US4568737A (en) 1983-01-07 1986-02-04 The Dow Chemical Company Dense star polymers and dendrimers
US4587329A (en) 1984-08-17 1986-05-06 The Dow Chemical Company Dense star polymers having two dimensional molecular diameter
NL8900442A (nl) * 1989-02-22 1990-09-17 Stichting Rega V Z W Gesulfateerde vinylpolymeren in geneesmiddelen voor het behandelen van retrovirus-infecties.
JP2909500B2 (ja) * 1989-03-23 1999-06-23 ベルレックス、ラボラトリーズ、レンコーポレイテッド 水溶性抗高脂質血症剤として有用な官能化側鎖を有するポリアミド
FR2669535A1 (fr) * 1990-11-26 1992-05-29 Medgenix Group Sa Utilisation a titre de medicament de macromolecules polysulfonees.
GB2260134A (en) * 1991-10-04 1993-04-07 Erba Carlo Spa Derivatives of poly-5-amino-3-carboxy-1-methyl compounds
KR0179675B1 (ko) * 1992-01-14 1999-03-20 나까토미 히로타카 콜레스테롤저하제
HUT72993A (en) * 1992-08-19 1996-06-28 Merrell Dow Pharma Process to prepare phatmaceutical compns. contg antiangiogenic oligomers
US5460807A (en) * 1992-08-19 1995-10-24 Merrell Dow Pharmaceuticals Inc. Antiproliferative oligomers
IL108951A0 (en) * 1994-03-13 1994-06-24 Hadasit Med Res Service Pharmaceutical compositions containing polysulfated polysaccharides
JPH07267879A (ja) 1994-03-30 1995-10-17 Unitika Ltd 血管新生阻害剤
AUPM623994A0 (en) * 1994-06-15 1994-07-07 Biomolecular Research Institute Limited Antiviral dendrimers

Also Published As

Publication number Publication date
EP0927217B1 (en) 2006-05-03
AU3330297A (en) 1998-02-10
CN1161128C (zh) 2004-08-11
KR100564714B1 (ko) 2006-03-28
ES2260796T3 (es) 2006-11-01
DE69735810T2 (de) 2006-12-21
NZ333488A (en) 2000-07-28
US6426067B1 (en) 2002-07-30
BR9710375A (pt) 1999-08-17
AUPO104496A0 (en) 1996-08-08
WO1998003573A1 (en) 1998-01-29
CN1225654A (zh) 1999-08-11
AU715761B2 (en) 2000-02-10
CA2262862A1 (en) 1998-01-29
EP0927217A1 (en) 1999-07-07
PT927217E (pt) 2006-08-31
EP0927217A4 (en) 2003-04-23
ATE325154T1 (de) 2006-06-15
CA2262862C (en) 2005-10-04
JP2000516211A (ja) 2000-12-05
KR20000067876A (ko) 2000-11-25
DE69735810D1 (de) 2006-06-08

Similar Documents

Publication Publication Date Title
DK0927217T3 (da) Antiangiogene forbindelser
DK0765357T3 (da) Antivirale dendrimerer
ATE268806T1 (de) Lichtemittierende dendrimere
NO901935D0 (no) Stroemfordeler for elektriske installasjoner.
NZ333541A (en) Antiviral polyionic linear polymers for treatment of HIV, RSV, influenza, hepatitis and other enveloped viruses
IT1295933B1 (it) 2-(2'-idrossifenil)benzotriazoli e procedimento per la loro preparazione
IT8821185A0 (it) Turbopompa molecolare.
DE68903092D1 (de) Laktamimide in der behandlung arzneiresistenter protozoeninjektionen.
ATE231131T1 (de) Verbindungen mit wachtumshormon freisetzenden eigenschaften
NO980643L (no) Propylendopeptidase inhibitorer
FR2643906B1 (fr) Copolymere a blocs polyester-silicone degradable par hydrolyse
DE60007851D1 (de) Zusammensetzungen und verfahren für die kontrolle von klebenden verunreinigungen
DE3791053T1 (de) Vakuum-molekularpumpe
NO924361L (no) Formazan parasittiske midler
ES2038665T3 (es) Procedimiento de sintesis de penems.
EA199900174A1 (ru) Способ лечения биполярного расстройства
ATE22293T1 (de) Substituierte tetrahydropyridazino(1,6a)benzimidazole.
ES2097274T3 (es) Composiciones polimericas autoextinguibles.
MX9801792A (es) Inhibidores cicloantihelminticos.
TR199801858T2 (xx) Kristalize edilebilir polialkilennaftalat'tan mamul amorf plaka.
FI943797A0 (fi) Virusvastaiset tiatsolit
ES2160969T3 (es) Derivados anticonvulsivos utiles en el tratamiento de la psoriasis.
BR9901387A (pt) Composições para a cura de polìmero.
DE3887585D1 (de) (Aryl oder heteroaromatische methyl)-2,2'-Bi-1H-Imidazole.
RO86650B1 (ro) Preparat farmaceutic pentru tratarea dermatozelor