DK0925295T3 - Derivater af N-benzensulfonyl-L-prolin som antagonister af receptoren B2 for bradykinin - Google Patents
Derivater af N-benzensulfonyl-L-prolin som antagonister af receptoren B2 for bradykininInfo
- Publication number
- DK0925295T3 DK0925295T3 DK97935612T DK97935612T DK0925295T3 DK 0925295 T3 DK0925295 T3 DK 0925295T3 DK 97935612 T DK97935612 T DK 97935612T DK 97935612 T DK97935612 T DK 97935612T DK 0925295 T3 DK0925295 T3 DK 0925295T3
- Authority
- DK
- Denmark
- Prior art keywords
- group
- pct
- bradykinin
- benzenesulfonyl
- proline
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Engineering & Computer Science (AREA)
- Neurosurgery (AREA)
- Diabetes (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Endocrinology (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pyrrole Compounds (AREA)
- Peptides Or Proteins (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9609327A FR2751650B1 (fr) | 1996-07-24 | 1996-07-24 | Nouveaux composes de n-benzenesulfonyl-l-proline, procede de preparation et utilisation en therapeutique |
| PCT/FR1997/001377 WO1998003503A1 (fr) | 1996-07-24 | 1997-07-23 | Derives de n-benzenesulfonyl-l-proline en tant qu'agonistes de la bradykinine b2 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0925295T3 true DK0925295T3 (da) | 2002-01-28 |
Family
ID=9494439
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK97935612T DK0925295T3 (da) | 1996-07-24 | 1997-07-23 | Derivater af N-benzensulfonyl-L-prolin som antagonister af receptoren B2 for bradykinin |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US6071917A (xx) |
| EP (1) | EP0925295B1 (xx) |
| JP (1) | JP2000514818A (xx) |
| AT (1) | ATE206419T1 (xx) |
| AU (1) | AU3853697A (xx) |
| CA (1) | CA2261743A1 (xx) |
| DE (1) | DE69707141T2 (xx) |
| DK (1) | DK0925295T3 (xx) |
| ES (1) | ES2167768T3 (xx) |
| FR (1) | FR2751650B1 (xx) |
| PL (1) | PL186396B1 (xx) |
| PT (1) | PT925295E (xx) |
| TR (1) | TR199900096T2 (xx) |
| WO (1) | WO1998003503A1 (xx) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2765222B1 (fr) * | 1997-06-27 | 1999-12-31 | Fournier Ind & Sante | Nouveaux composes de n-benzenesulfonyl-l-proline, procede de preparation et utilisation en therapeutique |
| KR100579792B1 (ko) * | 1998-05-13 | 2006-05-12 | 동화약품공업주식회사 | 신규 2,5-피리딘디카복실산 유도체 |
| FR2790260B1 (fr) * | 1999-02-26 | 2001-05-04 | Fournier Ind & Sante | Nouveaux composes de n-(benzenesulfonamide), procede de preparation et utilisation en therapeutique |
| CA2364178C (en) * | 2000-12-05 | 2006-01-10 | Yasuhiro Katsu | N-benzenesulfonyl l-proline compounds as bradykinin antagonists |
| FR2819254B1 (fr) * | 2001-01-08 | 2003-04-18 | Fournier Lab Sa | Nouveaux composes de la n-(phenylsulfonyl) glycine, leur procede de preparation et leur utilisation pour obtenir des compostions pharmaceutiques |
| EP1914236A1 (en) | 2002-04-10 | 2008-04-23 | Ortho-McNeil Pharmaceutical, Inc. | Novel heteroaryl alkylamide derivatives useful as bradykinin receptor modulators |
| ITMI20021247A1 (it) | 2002-06-07 | 2003-12-09 | Menarini Ricerche Spa | Antagonisti basici non peptidici della bradichinina e loro impiego informulazioni farmaceutiche |
| FR2840897B1 (fr) * | 2002-06-14 | 2004-09-10 | Fournier Lab Sa | Nouveaux derives d'arylsulfonamides et leur utilisation en therapeutique |
| DE10304994A1 (de) * | 2003-02-07 | 2004-09-02 | Aventis Pharma Deutschland Gmbh | Die Verwendung von Antagonisten des Bradykinin-B2 Rezeptors zur Behandlung von Osteoarthrose |
| EA008921B1 (ru) | 2003-03-25 | 2007-08-31 | Лаборатуар Фурнье С.А. | Производные бензолсульфонамидов, способ их получения и их применение для лечения боли |
| DE102005013967A1 (de) * | 2004-11-05 | 2006-10-05 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue Bradykinin-B1-Antagonisten, Verfahren zu deren Herstellung sowie deren Verwendung als Arzneimittel |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3617183A1 (de) * | 1985-11-16 | 1987-05-27 | Bayer Ag | Substituierte benzylether |
| DE3632329A1 (de) * | 1986-09-24 | 1988-03-31 | Bayer Ag | Substituierte phenylsulfonamide |
| AU686115B2 (en) * | 1992-11-02 | 1998-02-05 | Fujisawa Pharmaceutical Co., Ltd. | Imidazo (I,2-a) pyridine derivatives as bradykinin antagonists, pharmaceuticals and processes for their preparation |
| AU680870B2 (en) * | 1993-04-28 | 1997-08-14 | Astellas Pharma Inc. | New heterocyclic compounds |
| CN1168667A (zh) * | 1994-10-27 | 1997-12-24 | 藤沢药品工业株式会社 | 用作缓激肽拮抗剂的吡啶并嘧啶酮，喹啉和稠合的n-杂环化合物 |
| FR2735128B1 (fr) * | 1995-06-07 | 1997-07-25 | Fournier Ind & Sante | Nouveaux composes de benzenesulfonamide, leur procede de preparation et utilisation en therapeutique. |
| FR2737892B1 (fr) * | 1995-08-17 | 1997-10-24 | Fournier Ind & Sante | Nouveaux composes de benzenesulfonamide, procede de preparation et utilisation en therapeutique |
| FR2743073B1 (fr) * | 1995-12-29 | 1998-02-20 | Fournier Ind & Sante | Nouveaux composes de 1-benzenesulfonylpyrrolidine, procede de preparation et utilisation en therapeutique |
-
1996
- 1996-07-24 FR FR9609327A patent/FR2751650B1/fr not_active Expired - Fee Related
-
1997
- 1997-07-23 JP JP10506663A patent/JP2000514818A/ja active Pending
- 1997-07-23 AT AT97935612T patent/ATE206419T1/de not_active IP Right Cessation
- 1997-07-23 EP EP97935612A patent/EP0925295B1/fr not_active Expired - Lifetime
- 1997-07-23 ES ES97935612T patent/ES2167768T3/es not_active Expired - Lifetime
- 1997-07-23 DE DE69707141T patent/DE69707141T2/de not_active Expired - Fee Related
- 1997-07-23 PL PL97331347A patent/PL186396B1/pl not_active IP Right Cessation
- 1997-07-23 US US09/230,334 patent/US6071917A/en not_active Expired - Fee Related
- 1997-07-23 AU AU38536/97A patent/AU3853697A/en not_active Abandoned
- 1997-07-23 PT PT97935612T patent/PT925295E/pt unknown
- 1997-07-23 CA CA002261743A patent/CA2261743A1/en not_active Abandoned
- 1997-07-23 TR TR1999/00096T patent/TR199900096T2/xx unknown
- 1997-07-23 DK DK97935612T patent/DK0925295T3/da active
- 1997-07-23 WO PCT/FR1997/001377 patent/WO1998003503A1/fr active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| PL186396B1 (pl) | 2004-01-30 |
| ATE206419T1 (de) | 2001-10-15 |
| PT925295E (pt) | 2002-03-28 |
| EP0925295A1 (fr) | 1999-06-30 |
| FR2751650A1 (fr) | 1998-01-30 |
| PL331347A1 (en) | 1999-07-05 |
| DE69707141D1 (de) | 2001-11-08 |
| WO1998003503A1 (fr) | 1998-01-29 |
| DE69707141T2 (de) | 2002-06-27 |
| TR199900096T2 (xx) | 1999-03-22 |
| FR2751650B1 (fr) | 1998-10-09 |
| ES2167768T3 (es) | 2002-05-16 |
| JP2000514818A (ja) | 2000-11-07 |
| CA2261743A1 (en) | 1998-01-29 |
| AU3853697A (en) | 1998-02-10 |
| US6071917A (en) | 2000-06-06 |
| EP0925295B1 (fr) | 2001-10-04 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MY133223A (en) | Neuropeptide y5 receptor antagonists | |
| DK1173433T3 (da) | Cyanopyrroler som progesteronreceptoragonister | |
| DK0794949T3 (da) | Hidtil ukendte 3,5-dioxo-(2H,4H)-1,2,4-triazinderivater, fremstilling heraf og deres anvendelse som lægemidler | |
| MY146532A (en) | Thiazole derivative | |
| HUP0002461A2 (hu) | Triciklusos benzotiepin- vagy benzoxepinszármazékok és ezeket tartalmazó gyógyszerkészítmények | |
| DK0925295T3 (da) | Derivater af N-benzensulfonyl-L-prolin som antagonister af receptoren B2 for bradykinin | |
| SE9603283D0 (sv) | New compounds | |
| NO20001514L (no) | Vitronectin-reseptor-antagonist | |
| DK1059283T3 (da) | Fremgangsmåde til fremstilling af neuraminidase-inhibitor ro-64-0796 | |
| DK0813411T3 (da) | Anvendelse af vincopetinderivater til hæmning af dannelse eller afsondring af amyloid -protein | |
| PT944618E (pt) | Novos compostos de n-benzenossulfonilo-1-prolina processo de preparacao e utilizacao em terapia | |
| DK0885004T3 (da) | Anvendelse af 4-phenyl-3,6-dihydro-2H-pyridyl-derivater som NMDA-receptor-undertypeblokkere | |
| DE69624459T2 (de) | Kondensierte indan-derivate und ihre salze | |
| RS50790B (sr) | Korišćenje derivata piridoindolona za spravljanje lekova | |
| DK0687257T3 (da) | 4-amino-2-(hetero)aryl-butanamider anvendelige som 5HT1A-antagonister | |
| DK1140919T3 (da) | 1,4-Disubstituerede cyclohexanderivater til behandling af depression | |
| ATE200673T1 (de) | 1,9-diazabicyclo(4.3.0)nona-3,8-dienderivate | |
| DE60239324D1 (de) | Phenyl- und pyridyl-piperidine mit tnf-wirkung | |
| EP0313311A3 (en) | Herbicidal sulfonamides | |
| ATE262522T1 (de) | Benzimidazolverbindungen | |
| DK0651747T3 (da) | Carbostyrilderivater | |
| ES2056025A1 (es) | Nuevos derivados de indol. |